Onglyza combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hypersensitivity Other Serious 1/1/2010 54 Female 2/26/2010 Physician United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 1/20/2010 51 Female 2/26/2010 Physician United States
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 72 Female 130 lb 3/16/2010 Physician Germany
Primary
Secondary
Concomitant
Haematochezia Other Serious 74 Male 187 lb 3/23/2010 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 62 Female 3/30/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 62 Female 3/26/2010 Physician United States
Primary
Secondary
Concomitant
Haematochezia Other Serious 74 Male 187 lb 4/4/2010 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred 62 Female 5/27/2010 Physician United States
Primary
Secondary
Concomitant
Impaired Driving Ability 2/15/2010 44 Male 5/27/2010 Physician United States
Primary
Concomitant
Rash Pruritic 51 Male 5/27/2010 Physician United States
Primary
Concomitant
Vulvovaginal Pain 77 Female 161 lb 5/27/2010 Consumer United States
Primary
Concomitant
Headache Other Serious 6/2/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Myalgia Other Serious 2/26/2010 70 Male 181 lb 6/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Angioedema Other Serious 2/23/2010 49 Male 7/21/2010 Other Health Professional United States
Primary
Concomitant
Visual Impairment Other Serious 3/1/2010 76 Male 209 lb 7/22/2010 Physician Germany
Primary
Concomitant
Angioedema Other Serious 7/19/2010 61 Female 209 lb 7/29/2010 Physician United States
Primary
Concomitant
Angioedema Other Serious 6/29/2010 49 Male 284 lb 7/29/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 6/29/2010 51 Female 196 lb 8/24/2010 Physician Germany
Primary
Concomitant
Vision Blurred 1/1/2010 62 Female 8/25/2010 Physician United States
Primary
Secondary
Concomitant
Arthralgia 5/17/2010 70 Female 179 lb 8/25/2010 Physician United States
Primary
Concomitant
Pruritus 7/12/2010 44 Male 8/25/2010 Consumer United States
Primary
Concomitant
Feeling Hot 12/14/2009 65 Male 8/28/2010 Consumer United States
Primary
Concomitant
Pneumonia Other Serious 67 Female 9/6/2010 Physician Brazil
Primary
Secondary
Concomitant
Vomiting Other Serious 6/26/2010 51 Female 196 lb 9/15/2010 Physician Germany
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 10/12/2010 74 Female 10/24/2010 Physician Austria
Primary
Concomitant
Transaminases Increased Hospitalization 9/20/2010 59 Male 245 lb 10/28/2010 Physician Germany
Primary
Secondary
Transaminases Increased Hospitalization 9/20/2010 59 Male 245 lb 11/1/2010 Physician Germany
Primary
Secondary
Transaminases Increased Hospitalization 9/20/2010 59 Male 245 lb 11/1/2010 Physician Germany
Primary
Secondary
Transaminases Increased Other Serious 9/20/2010 59 Male 11/2/2010 Physician Germany
Primary
Secondary
Pancreatic Carcinoma Other Serious 10/12/2010 74 Female 11/14/2010 Physician Austria
Primary
Concomitant
Pancreatic Carcinoma Other Serious 10/12/2010 74 Female 11/16/2010 Physician Austria
Primary
Concomitant
Pulmonary Embolism Death 7/2/2010 69 Female 176 lb 11/22/2010 Physician Germany
Primary
Concomitant
Blood Creatinine Increased 8/25/2010 39 Male 11/23/2010 Other Health Professional United States
Primary
Concomitant
Hepatic Enzyme Increased 67 Female 11/23/2010 Physician United States
Primary
Concomitant
Sudden Death Death 7/2/2010 69 Female 176 lb 12/16/2010 Physician Germany
Primary
Concomitant
Transaminases Increased Hospitalization 9/20/2010 59 Male 245 lb 12/22/2010 Physician Germany
Primary
Secondary
Transaminases Increased Hospitalization 9/20/2010 59 Male 245 lb 12/30/2010 Physician Germany
Primary
Secondary
Gamma-glutamyltransferase Increased Hospitalization 9/20/2010 59 Male 245 lb 1/3/2011 Consumer Germany
Primary
Secondary
Abdominal Pain Hospitalization 8/1/2010 Female 1/11/2011 Consumer United States
Primary
Concomitant
Pancreatitis Acute Other Serious 11/1/2010 71 Female 187 lb 1/12/2011 Consumer Greece
Primary
Concomitant
Back Disorder Hospitalization 62 Male 276 lb 2/8/2011 Consumer United States
Primary
Concomitant
Transaminases Increased Hospitalization 9/20/2010 59 Male 245 lb 3/1/2011 Consumer Germany
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 9/20/2010 59 Male 245 lb 3/3/2011 Physician Germany
Primary
Secondary
Concomitant
Ascites Hospitalization 9/20/2010 59 Male 3/7/2011 Physician Germany
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 9/20/2010 59 Male 245 lb 3/9/2011 Consumer Germany
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 9/20/2010 59 Male 245 lb 3/14/2011 Physician Germany
Primary
Secondary
Concomitant
Escherichia Infection Other Serious 9/20/2010 59 Male 3/14/2011 Physician Germany
Primary
Secondary
Concomitant
Sensitivity Of Teeth Disability 12/6/2010 80 Male 150 lb 3/16/2011 Consumer United Kingdom
Primary
Concomitant
Portal Hypertension Hospitalization 9/20/2010 59 Male 231 lb 3/15/2011 Physician Germany
Primary
Secondary
Concomitant
Hearing Impaired Other Serious 61 Female 4/6/2011 Consumer Finland
Primary
Concomitant
Urinary Tract Infection Hospitalization 9/20/2010 59 Male 231 lb 3/24/2011 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 51 Female 195 lb 4/13/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 51 Female 194 lb 4/21/2011 Consumer United States
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2009 68 Female 5/11/2011 Consumer United States
Primary
Concomitant
Poor Peripheral Circulation Other Serious 1/1/2009 68 Female 5/13/2011 Physician United States
Primary
Concomitant
Localised Oedema Other Serious 70 Male 5/19/2011 Physician United States
Primary
Secondary
Concomitant
Cystitis 1/11/2011 59 Female 5/24/2011 Consumer United States
Primary
Concomitant
Insomnia Other Serious 5/1/2011 63 Male 172 lb 6/2/2011 Consumer United States
Primary
Concomitant
Dysstasia 4/1/2011 76 Male 6/7/2011 Consumer United States
Primary
Concomitant
Labyrinthitis Other Serious 5/23/2011 46 Female 234 lb 6/23/2011 Consumer Brazil
Primary
Concomitant
Weight Decreased Hospitalization 51 Female 195 lb 5/17/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Arthralgia 4/1/2011 76 Male 6/30/2011 Consumer United States
Primary
Concomitant
Blindness Disability 1/1/2011 77 Female 7/20/2011 Other Health Professional United States
Primary
Concomitant
Hyperkalaemia Life Threatening 5/30/2011 71 Female 7/22/2011 Physician France
Primary
Secondary
Concomitant
Blood Amylase Increased Other Serious 62 Male 7/25/2011 Consumer France
Primary
Secondary
Diarrhoea Hospitalization 8/1/2010 43 Female 281 lb 7/28/2011 Consumer United States
Primary
Concomitant
Chest Pain 5/1/2011 68 Male 8/1/2011 Consumer United States
Primary
Concomitant
Abdominal Pain Hospitalization 8/1/2010 43 Female 281 lb 8/3/2011 Physician United States
Primary
Concomitant
Tachyphrenia 5/26/2010 60 Male 230 lb 8/5/2011 Consumer United States
Primary
Concomitant
Pruritus 7/25/2010 70 Male 300 lb 8/5/2011 Consumer United States
Primary
Concomitant
Pruritus Other Serious 11/24/2010 68 Female 179 lb 8/12/2011 Physician Denmark
Primary
Concomitant
Diarrhoea Life Threatening 5/25/2011 71 Female 8/11/2011 France
Primary
Secondary
Concomitant
Chest Pain Hospitalization 7/18/2011 73 Male 154 lb 9/7/2011 Consumer United Kingdom
Primary
Concomitant
Angioedema Life Threatening 11/24/2010 68 Female 179 lb 9/12/2011 Physician Denmark
Primary
Concomitant
Hyperhidrosis 8/19/2011 70 Male 11/23/2011 Consumer United States
Primary
Concomitant
Mood Swings 3/24/2011 65 Female 132 lb 11/23/2011 Consumer United States
Primary
Secondary
Nausea 59 Female 201 lb 11/23/2011 Consumer United States
Primary
Concomitant
Lip Oedema 10/18/2010 71 Male 11/23/2011 Physician United States
Primary
Concomitant
Nervousness 9/1/2011 68 Female 11/23/2011 Consumer United States
Primary
Concomitant
Abdominal Pain Upper Hospitalization 9/26/2011 57 176 lb 11/28/2011 Physician Germany
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 9/26/2011 57 176 lb 12/1/2011 Consumer Germany
Primary
Secondary
Concomitant
Diabetes Mellitus Hospitalization 11/1/2011 63 Female 280 lb 12/9/2011 Consumer United States
Primary
Secondary
Concomitant
Diarrhoea 8/1/2010 61 Male 12/20/2011 Consumer United States
Primary
Concomitant
Visual Impairment Other Serious 10/1/2011 58 Male 291 lb 12/23/2011 Consumer Austria
Primary
Concomitant
Anger Other Serious 10/25/2011 63 Male 220 lb 12/28/2011 Consumer United Kingdom
Primary
Concomitant
Blood Glucose Increased Other Serious 1/1/2011 59 Female 165 lb 1/11/2012 Consumer Brazil
Primary
Secondary
Concomitant
Aggression Other Serious 10/1/2011 53 Male 220 lb 1/24/2012 Other Health Professional United Kingdom
Primary
Concomitant
Influenza 5/1/2010 62 Female 152 lb 1/27/2012 Consumer United States
Primary
Concomitant
Decreased Appetite 6/9/2011 64 Female 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Pain 11/7/2011 63 Female 1/29/2012 Consumer United States
Primary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 9/20/2010 59 Male 245 lb 2/2/2012 Physician Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 6/26/2010 51 Female 196 lb 2/9/2012 Consumer Germany
Primary
Concomitant
Diarrhoea Other Serious 1/28/2012 47 Female 2/26/2012 Pharmacist United Kingdom
Primary
Concomitant
Hyperhidrosis 8/19/2011 70 Male 2/28/2012 Physician United States
Primary
Concomitant
Laboratory Test Abnormal 75 Female 187 lb 2/28/2012 Consumer United States
Primary
Concomitant
Nephritis Other Serious 74 Female 3/6/2012 Other Health Professional United Kingdom
Primary
Concomitant
Decreased Appetite Other Serious 69 Female 132 lb 4/9/2012 Consumer Brazil
Primary
Secondary
Concomitant
Metastases To Prostate Other Serious Male 4/19/2012 Consumer United States
Primary
Concomitant
Off Label Use Other Serious 11/1/2011 63 Female 280 lb 4/26/2012 Physician United States
Primary
Secondary
Concomitant
Metastases To Liver Hospitalization 72 Female 5/2/2012 Physician Germany
Primary
Secondary
Metastases To Liver Hospitalization 63 Female 5/8/2012 Consumer Germany
Primary
Secondary
Musculoskeletal Disorder Other Serious 11/1/2011 63 Female 280 lb 5/9/2012 Consumer United States
Primary
Secondary
Concomitant
Pancreatic Carcinoma Life Threatening 72 Female 5/11/2012 Consumer Germany
Primary
Secondary
Concomitant
Hypoglycaemic Unconsciousness Other Serious Male 240 lb 5/17/2012 Consumer United States
Primary
Concomitant
Nausea Other Serious 1/1/2011 59 Female 165 lb 5/17/2012 Physician Brazil
Primary
Secondary
Concomitant
Asthenia Hospitalization 1/1/2006 47 Female 415 lb 5/25/2012 Consumer United States
Primary
Concomitant
Migraine Hospitalization 4/30/2012 62 Male 249 lb 5/29/2012 Consumer United Kingdom
Primary
Concomitant
Suicidal Ideation Hospitalization 4/28/2012 40 Male 254 lb 6/11/2012 Physician United States
Primary
Concomitant
Myocardial Infarction Death Male 6/21/2012 Physician United States
Primary
Concomitant
Diarrhoea Hospitalization 7/4/2012 67 Female 146 lb 7/10/2012 Physician United States
Primary
Secondary
Concomitant
Decreased Immune Responsiveness Hospitalization 8/1/2008 61 Male 264 lb 8/2/2012 Consumer United States
Primary
Secondary
Concomitant
Flushing Female 8/3/2012 Consumer United States
Primary
Concomitant
Low Density Lipoprotein Increased 3/1/2010 66 176 lb 8/3/2012 Consumer United States
Primary
Concomitant
Gait Disturbance Hospitalization 1/1/2009 57 Male 238 lb 8/8/2012 Physician United States
Primary
Concomitant
Memory Impairment Hospitalization Female 8/8/2012 Consumer Brazil
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 5/8/2012 51 Male 8/15/2012 Consumer United States
Primary
Concomitant
Burning Sensation 84 Male 8/15/2012 Consumer United States
Primary
Concomitant
Gallbladder Disorder Hospitalization 7/1/2012 60 Female 179 lb 8/21/2012 Consumer Brazil
Primary
Concomitant
Weight Increased Hospitalization 2009 Male 238 lb 11/8/2012 Physician Us
Primary
Concomitant
Poor Peripheral Circulation Other Serious 11/2011 64 Female 280 lb 3/7/2013 Consumer Us
Primary
Secondary
Concomitant
Vitamin D Deficiency Other Serious 2006 Male 250 lb 8/28/2012 Consumer Us
Primary
Secondary
Concomitant
Spinal Osteoarthritis Hospitalization 8/2008 Male 264 lb 11/15/2012 Consumer Us
Primary
Secondary
Concomitant
Spinal Osteoarthritis Other Serious 8/2008 62 Male 264 lb 7/9/2013 Consumer Us
Primary
Secondary
Concomitant
Hepatocellular Injury Other Serious 3/23/2012 56 Female 10/1/2012 Other Health Professional Fr
Primary
Secondary
Concomitant
Ocular Hyperaemia Other Serious 8/1/2012 69 Female 140 lb 10/31/2012 Consumer Us
Primary
Concomitant
Non-alcoholic Steatohepatitis Hospitalization 11/27/2012 66 Male 12/17/2012 Physician At
Primary
Secondary
Concomitant
Hypertension 78 Female 170 lb 1/8/2013 Consumer Us
Primary
Secondary
Concomitant
Insomnia 10/27/2012 64 Male 1/31/2013 Consumer Country Not Specified
Primary
Concomitant
Pain In Extremity 75 Female 1/31/2013 Consumer Country Not Specified
Primary
Concomitant
Urosepsis Other Serious 2010 75 Female 1/30/2013 Physician Country Not Specified
Primary
Secondary
Concomitant
Pneumonia Other Serious Female 4/18/2013 Consumer Br
Primary
Secondary
Concomitant
Injury Death 82 NotSpecified 3/6/2013 Pharmacist Us
Primary
Concomitant
Malignant Melanoma Other Serious 9/2012 Male 160 lb 3/1/2013 Other Health Professional Us
Primary
Concomitant
Ileus Other Serious 3/2013 57 Male 165 lb 5/22/2013 Physician Us
Primary
Concomitant
Myocardial Infarction Death 75 Male 5/3/2013 Consumer Us
Primary
Concomitant
Sinus Disorder Other Serious 68 Male 234 lb 4/19/2013 Consumer Us
Primary
Secondary
Concomitant
Visual Impairment Life Threatening Female 183 lb 4/19/2013 Consumer Br
Primary
Concomitant
Epistaxis 4/24/2012 84 Male 133 lb 9/13/2013 Consumer Us
Primary
Concomitant
Thyroid Neoplasm Other Serious 2009 68 Female 137 lb 5/24/2013 Consumer Us
Primary
Secondary
Concomitant
Weight Increased Hospitalization 2004 64 Male 260 lb 7/8/2013 Consumer Us
Primary
Concomitant
Anosmia Other Serious 68 Male 234 lb 4/19/2013 Consumer Us
Primary
Secondary
Concomitant
Pruritus Male 180 lb 7/30/2013 Consumer Country Not Specified
Primary
Concomitant
Diarrhoea 8/2012 66 Male 249 lb 7/30/2013 Consumer Country Not Specified
Primary
Concomitant
Dermatitis Psoriasiform Hospitalization 6/15/2013 86 Female 8/15/2013 Physician Us
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 8/22/2013 86 Male 300 lb 10/21/2013 Physician Us
Primary
Concomitant
Neuropathy Peripheral Hospitalization Female 188 lb 9/19/2013 Physician Us
Primary
Concomitant
Fall Hospitalization 8/27/2013 62 Male 203 lb 9/20/2013 Physician Us
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 2012 61 Female 219 lb 9/30/2013 Physician Us
Primary
Concomitant
Therapeutic Response Decreased Male 186 lb 10/1/2013 Physician Us
Primary
Concomitant
Multi-organ Failure Death 9/24/2013 NotSpecified 10/3/2013 Other Health Professional De
Primary
Concomitant

Drug Data