Simvastatin combined with Venlafaxine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Leukopenia Death 63 Male 1/29/2009 Consumer New Zealand
Primary
Secondary
Hemiparesis Other Serious 11/1/2008 57 Female 5/28/2009 Physician New Zealand
Primary
Concomitant
Rash Generalised Other Serious 9/1/2009 35 Female 9/22/2009 Physician United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 8/17/2009 Female 9/23/2009 United Kingdom
Primary
Concomitant
Vertigo Other Serious 72 Female 9/25/2009 Physician Germany
Primary
Secondary
Vertigo Other Serious 72 Female 9/25/2009 Physician Germany
Primary
Secondary
Urine Odour Abnormal Other Serious Male 9/29/2009 Canada
Primary
Concomitant
Urticaria Other Serious 5/1/2009 Female 346 lb 10/13/2009 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 10/19/2009 Pharmacist United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 2/1/2008 45 Female 256 lb 10/14/2009 United States
Primary
Concomitant
Mental Status Changes Required Intervention 8/29/2009 53 Female 115 lb 8/31/2009 Pharmacist United States
Primary
Secondary
Concomitant
Wheezing Other Serious 5/1/2009 Female 346 lb 11/3/2009 Physician United Kingdom
Primary
Concomitant
Wheezing Hospitalization 1/1/2009 Female 346 lb 11/30/2009 Physician United Kingdom
Primary
Concomitant
Orthostatic Hypotension Hospitalization 10/1/2009 Female 12/14/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 10/1/2009 57 Female 12/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Muscle Spasms 11/27/2009 64 Male 154 lb 12/31/2009 Consumer United States
Primary
Concomitant
Tongue Coated Other Serious 12/8/2009 48 Female 110 lb 1/7/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Oedema Life Threatening 1/20/2006 48 Female 298 lb 1/18/2010 Consumer United Kingdom
Primary
Concomitant
Thrombocytopenia Life Threatening 68 Male 198 lb 1/21/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intentional Overdose Life Threatening 68 Male 198 lb 1/22/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Intentional Overdose Other Serious 68 Male 198 lb 1/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Feeling Abnormal Other Serious 8/15/2009 63 Male 217 lb 1/21/2010 Physician Netherlands
Primary
Secondary
Concomitant
Platelet Count Decreased Life Threatening 68 Male 1/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
Troponin Increased 4/13/2009 72 Male 160 lb 4/21/2009 Pharmacist United States
Primary
Concomitant
Tachycardia Other Serious 42 Female 2/22/2010 Physician Netherlands
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 11/30/2005 Male 238 lb 3/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Tachycardia Other Serious 42 Female 3/15/2010 Other Health Professional Netherlands
Primary
Concomitant
Urinary Incontinence Hospitalization 1/11/2010 71 Male 3/11/2010 United States
Primary
Concomitant
Psoriasis Other Serious 1/1/2009 65 Male 265 lb 4/9/2010 Consumer United States
Primary
Concomitant
Surgical Procedure Repeated Hospitalization 4/2/2010 43 Male 256 lb 4/9/2010 Other Health Professional United States
Primary
Concomitant
Suicide Attempt Life Threatening 3/1/2010 48 Male 179 lb 4/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
Suicidal Ideation Hospitalization Male 5/6/2010 Physician United Kingdom
Primary
Concomitant
Spondylitis Other Serious 1/1/2009 65 Male 265 lb 5/7/2010 Consumer United States
Primary
Concomitant
Suicide Attempt Life Threatening 48 Male 5/3/2010 United Kingdom
Primary
Concomitant
Death Death 4/5/2010 40 Male 5/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Overdose Hospitalization 5/5/2010 Male 5/13/2010 Pharmacist United States
Primary
Concomitant
Syncope Other Serious 5/1/2010 67 Female 122 lb 5/20/2010 Consumer United States
Primary
Concomitant
Diarrhoea Hospitalization 1/1/2009 6/8/2010 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 8/15/2002 54 Male 205 lb 6/18/2010 United States
Primary
Concomitant
Spondylitis Other Serious 1/1/2009 65 Male 265 lb 6/22/2010 Consumer United States
Primary
Concomitant
Blood Potassium Increased Hospitalization 6/24/2010 Pharmacist United States
Primary
Concomitant
Diarrhoea Hospitalization 1/1/2009 7/5/2010 Physician United States
Primary
Concomitant
Spondylitis Other Serious 1/1/2009 65 Male 265 lb 7/8/2010 Consumer United States
Primary
Concomitant
Respiratory Tract Infection Life Threatening 4/8/2009 63 Male 7/8/2010
Primary
Secondary
Concomitant
Sleep Disorder 7/14/2007 56 Female 160 lb 7/14/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 55 Male 193 lb 7/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 7/12/2008 76 Male 7/21/2010 Lawyer United States
Primary
Concomitant
Myocardial Ischaemia Death 4/7/2010 40 Male 8/5/2010 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Other Serious 5/1/2010 67 Female 122 lb 8/11/2010 Consumer United States
Primary
Concomitant
Respiratory Tract Infection Life Threatening 4/8/2009 63 Male 8/12/2010
Primary
Secondary
Concomitant
Intracardiac Thrombus Hospitalization 57 Male 209 lb 8/17/2010 Pharmacist United States
Primary
Concomitant
Generalised Erythema Female 158 lb 8/29/2010 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/5/2001 58 Male 234 lb 9/1/2010 United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/1998 65 Female 104 lb 9/7/2010 Consumer United States
Primary
Secondary
Concomitant
Pruritus Other Serious 8/13/2010 60 Male 225 lb 9/9/2010 Physician United States
Primary
Secondary
Concomitant
Schizophrenia Hospitalization 7/27/2010 65 Female 9/10/2010 Consumer United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 7/12/2008 76 Male 9/15/2010 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus 1/29/2009 51 Female 250 lb 9/17/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 43 Female 178 lb 9/20/2010 United States
Primary
Concomitant
Nausea Other Serious 11/24/2004 71 Female 9/22/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Diabetes Mellitus Hospitalization 1/1/2008 36 Female 230 lb 9/14/2010 Consumer United States
Primary
Concomitant
Respiratory Tract Infection Life Threatening 4/8/2009 63 Male 11/1/2010
Primary
Secondary
Concomitant
Neutrophil Count Increased Other Serious 7/26/2010 43 Male 11/2/2010 Other Health Professional United Kingdom
Primary
Concomitant
Abdominal Pain Upper Female 11/12/2010 Consumer United States
Primary
Concomitant
Oropharyngeal Pain Other Serious 58 Female 12/9/2010 Other Health Professional United Kingdom
Primary
Concomitant
Prostatic Operation Other Serious 9/20/2010 75 Male 230 lb 12/14/2010 Consumer United States
Primary
Concomitant
Thrombotic Stroke Other Serious 1/1/2008 36 Female 230 lb 12/13/2010 Consumer United States
Primary
Concomitant
Toxicity To Various Agents Death 56 Female 1/5/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 77 Female 1/5/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 62 Male 1/5/2011 Other Health Professional United States
Primary
Secondary
Toxicity To Various Agents Death 77 Female 1/7/2011 Other Health Professional
Primary
Secondary
Cardio-respiratory Arrest Death 77 Female 1/7/2011 Physician United States
Primary
Secondary
Tuberculosis Other Serious 1/12/2011 Consumer Israel
Primary
Concomitant
Toxicity To Various Agents Death 56 Female 1/14/2011 Physician United States
Primary
Secondary
Death Death 56 Female 1/14/2011
Primary
Secondary
Death Death 62 Male 1/18/2011 Physician United States
Primary
Secondary
Injection Site Reaction 4/11/2010 55 Female 1/19/2011 United States
Primary
Concomitant
Fatigue 7/1/2010 67 Female 1/19/2011 Consumer
Primary
Secondary
Concomitant
General Physical Condition Abnormal Other Serious 7/26/2010 43 Male 1/20/2011 Physician United Kingdom
Primary
Concomitant
Cardio-respiratory Arrest Death 77 Female 1/21/2011 Physician United States
Primary
Secondary
Pubis Fracture Hospitalization 12/23/2010 77 Female 1/28/2011 Consumer Netherlands
Primary
Concomitant
Furuncle 9/18/2010 49 Male 1/30/2011 Consumer United States
Primary
Concomitant
Faecal Incontinence Other Serious 55 Male 193 lb 1/20/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Sluggishness Hospitalization 1/1/2011 42 Male 250 lb 2/2/2011 Consumer United States
Primary
Concomitant
Cardiac Arrest Death 77 Female 1/27/2011 Other Health Professional United States
Primary
Secondary
Poisoning Death 1/1/2009 62 Male 1/27/2011 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death Female 1/26/2011 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2009 77 Female 1/27/2011 Physician United States
Primary
Secondary
C-reactive Protein Increased Hospitalization 11/6/2010 78 Male 218 lb 2/10/2011 Physician Sweden
Primary
Secondary
Concomitant
Faeces Hard 9/1/2010 80 Male 2/10/2011 Consumer United States
Primary
Concomitant
Death Death 1/1/2009 56 Female 1/27/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 1/1/2009 56 Female 1/24/2011 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2009 77 Female 1/26/2011 Physician United States
Primary
Secondary
Joint Sprain Hospitalization 1/1/2011 42 Male 250 lb 2/14/2011 Consumer United States
Primary
Concomitant
Death Other Serious Female 254 lb 2/23/2011 Other Health Professional United States
Primary
Concomitant
Dehydration Other Serious 5/1/2010 67 Female 122 lb 2/24/2011 Consumer United States
Primary
Concomitant
Spinal Compression Fracture Other Serious 12/23/2010 77 Female 3/1/2011 Consumer Netherlands
Primary
Concomitant
Treatment Noncompliance Other Serious 2/22/2011 68 Female 3/2/2011 Consumer United States
Primary
Concomitant
Death Death Female 3/4/2011 Physician United States
Primary
Secondary
Pruritus Hospitalization 8/13/2010 60 Male 225 lb 3/4/2011 Physician United States
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 62 Male 3/6/2011 Other Health Professional United States
Primary
Secondary
Cardio-respiratory Arrest Death 77 Female 3/6/2011 Physician United States
Primary
Secondary
Multiple Drug Overdose Intentional Death 56 Female 3/7/2011 Physician United States
Primary
Secondary
Death Hospitalization 62 Male 2/24/2011 Physician United States
Primary
Concomitant
Multiple Drug Overdose Intentional Death 56 Female 3/8/2011 Physician United States
Primary
Secondary
Diarrhoea Other Serious 5/1/2010 67 Female 122 lb 3/9/2011 Consumer United States
Primary
Concomitant
Cardio-respiratory Arrest Death 62 3/11/2011 Physician United States
Primary
Secondary
Rash Other Serious 11/25/2010 63 Female 2/7/2011 Consumer United States
Primary
Concomitant
Drug Interaction Hospitalization 1/1/2009 81 Male 3/23/2011 Physician United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 56 Female 3/24/2011 Physician United States
Primary
Secondary
Respiratory Arrest Death 62 Male 3/24/2011 Physician United States
Primary
Secondary
Drug Ineffective 9/1/2010 80 Male 3/28/2011 Consumer United States
Primary
Concomitant
Restless Legs Syndrome 7/1/2010 67 Female 3/28/2011 Consumer United States
Primary
Secondary
Concomitant
Joint Swelling 1/11/2011 61 Female 3/28/2011 Consumer United States
Primary
Concomitant
Lethargy Other Serious Female 3/29/2011 Physician United Kingdom
Primary
Concomitant
Intentional Drug Misuse Death 56 Female 3/30/2011 Physician United States
Primary
Secondary
Fatigue Life Threatening 5/1/2010 46 Male 284 lb 4/9/2011 Consumer United States
Primary
Secondary
Concomitant
No Adverse Event 3/30/2011 55 Female 247 lb 4/12/2011 Consumer United States
Primary
Concomitant
Agranulocytosis Hospitalization 6/22/2010 60 Male 5/5/2011 Physician Spain
Primary
Concomitant
Urinary Incontinence Other Serious 5/11/2010 63 Female 148 lb 5/9/2011 Physician Belgium
Primary
Concomitant
Neck Pain Other Serious 5/11/2010 63 Female 148 lb 5/10/2011 Physician Belgium
Primary
Concomitant
Renal Mass Hospitalization 2/22/2011 72 Male 5/25/2011 Physician United Kingdom
Primary
Concomitant
Eye Swelling Other Serious 3/15/2011 52 Female 198 lb 5/27/2011 Physician United States
Primary
Concomitant
Periorbital Oedema Other Serious 3/15/2011 52 Female 198 lb 5/30/2011 Physician United States
Primary
Concomitant
Skin Ulcer Other Serious 1/13/2011 52 Female 141 lb 6/1/2011 Consumer United Kingdom
Primary
Concomitant
Constipation Hospitalization 2/22/2011 72 Male 6/8/2011 Other Health Professional United Kingdom
Primary
Concomitant
Fall Other Serious 1/7/2011 86 Male 134 lb 6/10/2011 Other Health Professional United Kingdom
Primary
Concomitant
Convulsion Life Threatening Female 6/13/2011 Pharmacist United Kingdom
Primary
Concomitant
Pubis Fracture Other Serious 12/23/2010 77 Female 6/9/2011 Physician Netherlands
Primary
Concomitant
Ligament Disorder Other Serious 64 Male 6/2/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Death Death 71 Female 154 lb 6/15/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Cyanosis Other Serious Female 6/17/2011 Physician United Kingdom
Primary
Concomitant
Ventricular Extrasystoles Other Serious 4/1/2011 51 Male 6/20/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Malaise Other Serious 6/14/2011 55 Male 6/21/2011 United States
Primary
Concomitant
Renal Failure Acute Disability 4/19/2011 42 Female 138 lb 6/21/2011 Physician United States
Primary
Secondary
Concomitant
Polycystic Ovaries Other Serious 1/1/2008 36 Female 240 lb 6/8/2011 Consumer United States
Primary
Concomitant
Rhinorrhoea Hospitalization 6/12/2011 55 Female 6/22/2011 Consumer United States
Primary
Concomitant
Renal Failure Acute Disability 4/19/2011 42 Female 138 lb 6/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Diabetes Mellitus Life Threatening Female 6/29/2011 Pharmacist United Kingdom
Primary
Concomitant
Personality Disorder Other Serious Female 6/30/2011 Physician United Kingdom
Primary
Concomitant
Skin Induration Death 1/1/2004 39 Female 117 lb 6/30/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Back Pain Other Serious 6/1/2008 53 Male 7/5/2011 Lawyer United States
Primary
Concomitant
Antipsychotic Drug Level Below Therapeutic Hospitalization 6/16/2011 37 Male 7/13/2011 Physician Australia
Primary
Concomitant
Blood Glucose Abnormal Hospitalization 6/12/2011 55 Female 7/13/2011 Consumer United States
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 7/26/2010 43 Male 8/2/2011 Other Health Professional United Kingdom
Primary
Concomitant
Drug Ineffective Other Serious 55 Female 237 lb 7/25/2011 Consumer United States
Primary
Concomitant
Pruritus Female 8/6/2011 Consumer United States
Primary
Concomitant
Anaphylactic Reaction Hospitalization 6/14/2011 55 Male 8/9/2011 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 7/1/2008 58 Female 165 lb 8/9/2011 Consumer Netherlands
Primary
Concomitant
Drug Eruption Disability 4/19/2011 42 Female 138 lb 8/9/2011 United States
Primary
Secondary
Concomitant

Drug Data