Keppra combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Speech Disorder Life Threatening 2/28/2006 Male 162 lb 3/2/2006 Other Health Professional United States
Primary
Concomitant
Thirst Life Threatening 2/28/2006 Male 162 lb 4/7/2006 Other Health Professional United States
Primary
Concomitant
Acute Febrile Neutrophilic Dermatosis Hospitalization 9/18/2006 50 Female 10/23/2006 Physician Belgium
Primary
Secondary
Concomitant
Acute Febrile Neutrophilic Dermatosis Hospitalization 9/14/2006 Female 10/31/2006 Physician Belgium
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 11/17/2006 64 Female 293 lb 11/27/2006 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 7/11/2006 68 Male 154 lb 12/19/2006 Germany
Primary
Concomitant
Rhabdomyolysis Other Serious 57 Male 2/28/2007 Physician United States
Primary
Secondary
Concomitant
Thyroid Cancer Other Serious 1/1/2004 Female 240 lb 4/11/2007 Consumer United States
Primary
Concomitant
Urethral Polyp Hospitalization 60 Female 8/6/2007 Physician United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 10/2/2007 Male 170 lb 10/3/2007 United States
Primary
Secondary
Concomitant
Thrombosis Life Threatening 10/2/2007 65 Male 170 lb 10/4/2007 United States
Primary
Secondary
Concomitant
Urethral Polyp Hospitalization 7/10/2007 60 Female 10/22/2007 Physician United States
Primary
Concomitant
Thrombosis Hospitalization 7/10/2007 60 Female 11/13/2007 Physician United States
Primary
Concomitant
Ventricular Tachycardia Death 10/14/2007 37 Female 146 lb 11/14/2007 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 25 Male 1/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 2/1/2008 Female 160 lb 3/6/2008 Consumer United States
Primary
Concomitant
Somnolence Hospitalization 1/12/2008 Male 4/2/2008 Physician Switzerland
Primary
Concomitant
Interacting
Weight Decreased Other Serious 25 Male 4/5/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2007 25 Male 4/26/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 2/13/2008 67 Female 4/29/2008 United States
Primary
Concomitant
Urinary Bladder Haemorrhage Hospitalization 7/10/2007 60 Female 5/19/2008 Physician United States
Primary
Concomitant
Syncope Hospitalization 4/12/2008 71 Female 6/11/2008 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Required Intervention 10/15/2007 60 Male 153 lb 7/24/2008 United States
Primary
Concomitant
Swollen Tongue Hospitalization 11/24/2007 Female 170 lb 7/30/2008 Consumer United States
Primary
Concomitant
Hallucination, Visual Hospitalization 7/1/2008 70 Female 143 lb 8/25/2008 Physician Germany
Primary
Concomitant
Dystonia Hospitalization 2/5/2008 Male 9/9/2008 Physician Denmark
Primary
Concomitant
Pancytopenia Other Serious 9/5/2008 73 Female 9/19/2008 Physician France
Primary
Concomitant
Pancytopenia Other Serious 9/5/2008 73 Female 10/2/2008 Physician France
Primary
Concomitant
Renal Impairment 8/1/2008 67 Male 11/14/2008 United States
Primary
Concomitant
Somnolence Hospitalization 7/1/2008 70 Female 143 lb 12/2/2008 Physician Germany
Primary
Concomitant
Sudden Cardiac Death Death 11/29/2008 Male 12/19/2008 Consumer United States
Primary
Concomitant
Syncope Hospitalization 6/12/2008 84 Female 156 lb 1/21/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Syncope Hospitalization 6/12/2008 84 Female 1/22/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Syncope Hospitalization 6/12/2008 1/26/2009 Physician Germany
Primary
Concomitant
Interacting
Syncope Hospitalization 6/12/2008 84 Female 1/22/2009 Physician Germany
Primary
Secondary
Concomitant
Syncope Hospitalization 6/12/2008 84 Female 156 lb 1/28/2009 Other Health Professional Germany
Primary
Concomitant
Interacting
Wrong Technique In Drug Usage Process Hospitalization 3/1/2009 Female 290 lb 4/2/2009 Pharmacist United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 3/1/2009 Female 290 lb 4/3/2009 Pharmacist United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 4/2/2009 87 Female 158 lb 4/9/2009 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 6/8/2007 5/1/2009 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/8/2007 5/1/2009 Other Health Professional United States
Primary
Concomitant
Pancreatitis Required Intervention 2/1/2009 57 Female 163 lb 3/2/2009 Pharmacist United States
Primary
Concomitant
Suicidal Ideation Life Threatening 2/1/2009 56 Female 170 lb 5/11/2009 Physician Germany
Primary
Concomitant
Syncope Hospitalization 6/12/2008 84 5/19/2009 Physician Germany
Primary
Concomitant
Interacting
Metastatic Malignant Melanoma Hospitalization 11/1/2005 69 Male 220 lb 5/15/2009 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/8/2007 Female 5/22/2009 Other Health Professional United States
Primary
Concomitant
Fatigue Hospitalization 62 Male 188 lb 5/22/2009 Pharmacist United States
Primary
Concomitant
Cardiac Pacemaker Insertion Other Serious 1/1/2008 53 Male 6/3/2009 Physician United States
Primary
Concomitant
Tongue Injury Hospitalization 4/15/2009 53 Male 163 lb 6/4/2009 Physician United States
Primary
Concomitant
Neutropenia Hospitalization 1/20/2009 65 Female 6/5/2009 France
Primary
Secondary
Concomitant
Epstein-barr Virus Associated Lymphoproliferative Disorder Other Serious 4/27/2009 69 Female 6/19/2009 Physician Germany
Primary
Concomitant
Epstein-barr Virus Infection Other Serious 4/27/2009 69 Female 6/24/2009 Physician Germany
Primary
Concomitant
Myalgia Other Serious 10/1/2008 76 Female 7/6/2009 Consumer United States
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 7/6/2009 Male 209 lb 7/17/2009 Physician United States
Primary
Concomitant
Epstein-barr Virus Infection Other Serious 4/27/2009 69 Female 7/14/2009 Physician Germany
Primary
Concomitant
Pyrexia Other Serious 4/27/2009 69 Female 8/7/2009 Physician Germany
Primary
Concomitant
Myocardial Infarction Other Serious 4/27/2009 69 Female 8/10/2009 Physician Germany
Primary
Concomitant
Septic Embolus Other Serious 4/27/2009 69 Female 9/2/2009 Physician Germany
Primary
Concomitant
Weight Increased Other Serious 12/1/2008 Male 9/23/2009 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 12/1/2008 Male 9/28/2009 Consumer United States
Primary
Concomitant
Psychotic Disorder Other Serious 9/11/2008 62 Male 174 lb 10/6/2009 Consumer United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 74 Female 165 lb 10/8/2009 Physician Germany
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 8/1/2009 59 Male 183 lb 10/20/2009 Consumer Germany
Primary
Secondary
Syncope Hospitalization 6/12/2008 84 Female 11/3/2009 Physician Germany
Primary
Secondary
Concomitant
Interacting
Delirium Other Serious Female 78 lb 11/6/2009 Physician Norway
Primary
Secondary
Concomitant
Syncope Hospitalization 6/12/2008 84 Female 156 lb 11/6/2009 Other Health Professional Germany
Primary
Concomitant
Interacting
Syncope Other Serious 6/12/2008 84 Female 156 lb 11/9/2009 Physician Germany
Primary
Concomitant
Interacting
Syncope Other Serious 6/12/2008 84 Female 11/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 71 Female 78 lb 11/9/2009 Norway
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 8/13/2008 Female 11/19/2009 Physician United States
Primary
Concomitant
Status Epilepticus Other Serious 9/14/2009 72 Female 11/25/2009 Physician Germany
Primary
Concomitant
Grand Mal Convulsion Other Serious 67 Female 185 lb 1/22/2010 United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 11/23/2008 Male 1/25/2010 Physician Switzerland
Primary
Secondary
Concomitant
Postictal State Other Serious 12/7/2008 Male 1/22/2010 Physician United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Life Threatening 11/21/2008 Male 1/29/2010 Other Health Professional France
Primary
Secondary
Concomitant
Thrombosis Other Serious 1/1/2008 68 Male 2/4/2010 Lawyer United States
Primary
Concomitant
Drug Ineffective 8/15/2009 65 Male 2/4/2010 Pharmacist United States
Primary
Concomitant
Grand Mal Convulsion Other Serious 67 Female 185 lb 2/15/2010 United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Life Threatening 11/10/2008 Male 1/28/2010 Other Health Professional France
Primary
Secondary
Concomitant
Taciturnity Hospitalization 10/1/2009 Female 2/9/2010 Sweden
Primary
Concomitant
Postictal State Other Serious 12/7/2008 Male 2/5/2010 Physician United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 1/1/2003 Female 2/25/2010 Consumer United States
Primary
Concomitant
Epilepsy Other Serious 2/23/2010 88 Male 3/25/2010 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 1/1/2005 Male 3/19/2010 Other Health Professional United Kingdom
Primary
Concomitant
Epilepsy Other Serious 2/23/2010 88 Male 3/26/2010 Other Health Professional United Kingdom
Primary
Concomitant
Underdose Other Serious 68 Female 4/8/2010 Consumer United States
Primary
Concomitant
Hemiparesis Hospitalization 4/1/2010 74 Male 220 lb 4/9/2010 Physician Spain
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2010 74 Male 220 lb 4/12/2010 Physician Spain
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 1/1/2008 68 Male 5/3/2010 Physician United States
Primary
Concomitant
Vomiting Hospitalization 12/13/2008 66 Female 220 lb 4/27/2010 Lawyer United States
Primary
Concomitant
Renal Failure Chronic Other Serious Male 159 lb 5/6/2010 Physician United States
Primary
Concomitant
Urinary Tract Infection Staphylococcal Hospitalization 4/1/2010 74 Male 220 lb 5/12/2010 Physician Spain
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/13/2008 66 Female 220 lb 5/20/2010 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 12/13/2008 66 Female 220 lb 5/28/2010 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 12/13/2008 66 Female 220 lb 6/8/2010 Lawyer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 9/1/2009 66 Female 6/9/2010 United Kingdom
Primary
Concomitant
Temperature Intolerance 2/2/2007 23 Female 240 lb 6/23/2010 Consumer United States
Primary
Concomitant
Death Death 64 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Underdose Other Serious 68 Female 6/25/2010 Consumer United States
Primary
Concomitant
Off Label Use Other Serious 12/1/2008 56 Male 7/1/2010 Physician Switzerland
Primary
Secondary
Concomitant
Overdose Other Serious Male 6/25/2010 Physician United States
Primary
Secondary
Concomitant
Nystagmus Other Serious 1/1/2009 66 7/9/2010 Consumer Sweden
Primary
Secondary
Concomitant
Nystagmus Other Serious 11/1/2009 67 Female 7/7/2010 Sweden
Primary
Secondary
Concomitant
Off Label Use Other Serious 12/1/2008 56 Male 8/6/2010 Physician United States
Primary
Secondary
Concomitant
Respiratory Distress Male 193 lb 8/9/2010 United States
Primary
Concomitant
Weight Decreased Hospitalization 6/1/2010 46 Female 160 lb 8/13/2010 United States
Primary
Concomitant
Overdose Other Serious Male 8/16/2010 Physician United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 6/26/2010 86 Female 8/25/2010 Spain
Primary
Concomitant
Hyponatraemia Hospitalization 3/20/2009 56 Female 192 lb 8/26/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Paraparesis Hospitalization 11/4/2009 54 Female 110 lb 9/7/2010 Physician Germany
Primary
Concomitant
Urinary Retention Other Serious 85 Female 9/9/2010 Sweden
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 3/20/2009 56 Female 192 lb 9/9/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 3/20/2009 56 Female 192 lb 9/9/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Urinary Retention Other Serious 85 Female 9/15/2010 Sweden
Primary
Secondary
Concomitant
Somnolence Other Serious 7/9/2010 57 Male 193 lb 9/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Paraparesis Hospitalization 11/4/2009 54 Female 110 lb 9/17/2010 Physician Germany
Primary
Concomitant
Hallucination, Visual Other Serious 56 Male 9/20/2010 Consumer United States
Primary
Concomitant
Somnolence Other Serious 7/9/2010 57 Male 193 lb 10/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 1/1/2008 68 Male 10/12/2010 Physician United States
Primary
Secondary
Concomitant
Lethargy Hospitalization 8/1/2010 95 Female 10/13/2010 Pharmacist United States
Primary
Concomitant
Somnolence Other Serious 7/9/2010 57 Male 193 lb 10/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 6/1/2010 46 Female 160 lb 10/13/2010 United States
Primary
Concomitant
Visual Field Defect Other Serious 1/1/2009 74 Female 10/25/2010 Consumer United States
Primary
Concomitant
Secretion Discharge 78 Male 10/13/2010 Consumer United States
Primary
Concomitant
Convulsion Other Serious 10/1/2010 Female 11/11/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 7/13/2010 52 Female 207 lb 11/12/2010 Consumer United States
Primary
Concomitant
Diarrhoea 1/1/2008 55 Female 11/18/2010 Consumer United States
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 8/11/2010 42 Female 150 lb 11/22/2010 Pharmacist United States
Primary
Concomitant
Osteomyelitis Disability 9/27/2010 71 Male 123 lb 12/3/2010 Physician Switzerland
Primary
Secondary
Concomitant
Drug Effect Decreased Other Serious 8/1/2009 56 Male 185 lb 10/28/2010 Physician United States
Primary
Concomitant
Osteomyelitis Disability 9/27/2010 12/6/2010 Physician Switzerland
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Disability 9/27/2010 71 Male 12/8/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Walking Aid User Other Serious 8/30/2010 43 Female 12/15/2010 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/1/2010 57 Male 210 lb 12/27/2010 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 10/29/2009 61 Female 12/31/2010 Physician United States
Primary
Concomitant
Cardiac Arrest Other Serious 12/3/2007 59 Female 1/4/2011 Lawyer United States
Primary
Concomitant
Chest Pain Other Serious Male 222 lb 1/11/2011 Consumer United States
Primary
Secondary
Concomitant
Joint Instability Hospitalization 11/11/2010 59 Female 157 lb 1/17/2011 Other Health Professional United States
Primary
Concomitant
Retinal Artery Embolism Hospitalization 9/1/2010 1/21/2011 Other Health Professional Germany
Primary
Concomitant
Anticonvulsant Drug Level Below Therapeutic 82 Female 174 lb 1/27/2011 Pharmacist United States
Primary
Concomitant
Joint Range Of Motion Decreased Disability Male 144 lb 1/28/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Circulatory Collapse Hospitalization 12/1/2010 62 Male 1/29/2011 Other Health Professional Sweden
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 11/6/2010 64 Female 182 lb 2/1/2011 Physician United States
Primary
Secondary
Concomitant
Hypertension Hospitalization Female 1/28/2011 Physician United States
Primary
Secondary
Concomitant
Convulsion Other Serious 2/12/2011 66 Male 2/18/2011 Consumer United States
Primary
Concomitant
Pancytopenia Hospitalization 12/29/2010 59 Female 2/8/2011 France
Primary
Concomitant
Hepatosplenomegaly Death 1/27/2011 68 Male 2/15/2011 Other Health Professional United States
Primary
Concomitant
Diarrhoea Hospitalization 8/14/2010 90 Male 160 lb 1/22/2011 Consumer United States
Primary
Concomitant
Respiratory Failure Death 12/3/2007 59 Female 152 lb 3/2/2011 Lawyer United States
Primary
Concomitant
Electroencephalogram Abnormal Hospitalization 4/20/2010 42 Female 2/17/2011 Consumer Belgium
Primary
Concomitant

Drug Data