Losartan Potassium combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Proteinuria Other Serious 7/7/2005 50 Female 1/30/2006 Brazil
Primary
Secondary
Concomitant
Proteinuria Other Serious 7/5/2005 50 Female 1/30/2006 Brazil
Primary
Secondary
Concomitant
Incoherent Hospitalization 6/14/2005 65 Male 3/6/2006 Other Health Professional Spain
Primary
Concomitant
Interacting
Necrosis Hospitalization 2/20/2006 65 Female 152 lb 3/8/2006 Physician Austria
Primary
Secondary
Concomitant
Metabolic Encephalopathy Other Serious 1/1/2005 65 Male 3/6/2006 Physician Germany
Primary
Secondary
Concomitant
Catheter Related Complication Other Serious 5/18/2004 81 Male 185 lb 3/14/2006 Consumer Canada
Primary
Concomitant
Catheter Site Haemorrhage Hospitalization 10/11/2004 65 Male 217 lb 12/21/2005 United States
Primary
Secondary
Concomitant
Spinal Haematoma Hospitalization 6/1/2005 50 Male 164 lb 12/21/2005 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 78 Male 165 lb 12/21/2005 Consumer United States
Primary
Concomitant
Tongue Ulceration Other Serious 12/21/2005 Male 395 lb 3/16/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Other Serious 2/17/2006 75 Male 3/31/2006 Other Health Professional France
Primary
Concomitant
Renal Failure Acute Other Serious 2/17/2006 75 Male 223 lb 4/5/2006 United Kingdom
Primary
Concomitant
Visual Field Defect Other Serious 9/1/2005 75 Female 240 lb 2/9/2006 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 2/17/2006 75 Male 223 lb 5/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 65 Female 152 lb 5/12/2006 Physician Austria
Primary
Secondary
Concomitant
Lethargy Hospitalization 4/23/2006 77 Male 208 lb 5/15/2006 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Required Intervention 3/7/2006 57 Male 320 lb 3/23/2006 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 55 Male 5/26/2006 Consumer United Kingdom
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 5/21/2006 77 Male 211 lb 5/25/2006 Pharmacist United States
Primary
Concomitant
Blood Parathyroid Hormone Increased 8/22/2005 Male 3/13/2006 United States
Primary
Secondary
Concomitant
Blood Parathyroid Hormone Increased 8/22/2005 Male 3/13/2006 United States
Primary
Secondary
Concomitant
Somnolence Other Serious 55 Male 6/1/2006 Consumer United Kingdom
Primary
Concomitant
Somnolence Other Serious 55 Male 6/9/2006 Physician United Kingdom
Primary
Concomitant
Soft Tissue Necrosis Hospitalization 1/1/2005 Male 132 lb 6/9/2006 Physician United States
Primary
Concomitant
Myalgia Other Serious 5/22/2006 64 Male 254 lb 6/28/2006 Pharmacist United States
Primary
Concomitant
Hepatic Lesion Hospitalization 5/25/2006 64 Female 6/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Nasopharyngitis Hospitalization 5/8/2006 73 Female 7/27/2006 Other Health Professional Japan
Primary
Concomitant
Urinary Retention Death 10/14/2006 69 Female 11/27/2006 Other Health Professional Sweden
Primary
Concomitant
Vomiting Other Serious 10/21/2006 85 Female 12/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 11/17/2006 57 Female 211 lb 11/30/2006 Pharmacist United States
Primary
Concomitant
Therapeutic Agent Toxicity Life Threatening 7/13/2006 72 Male 172 lb 10/23/2006 Pharmacist United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 9/7/2006 46 Male 1/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urticaria Other Serious 12/1/2006 57 Female 1/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Angioedema Other Serious 11/14/2006 76 Male 220 lb 11/14/2006 Pharmacist United States
Primary
Concomitant
Cough Other Serious 12/28/2006 75 Male 218 lb 12/28/2006 Pharmacist United States
Primary
Concomitant
Immunodeficiency Other Serious 10/1/2005 70 220 lb 2/6/2007 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/8/2006 54 Male 193 lb 12/20/2006 Pharmacist United States
Primary
Concomitant
Duodenal Ulcer Perforation Hospitalization Female 2/5/2007 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 87 Male 2/7/2007 Physician Spain
Primary
Secondary
Concomitant
Headache Hospitalization 12/11/2006 76 Male 198 lb 2/5/2007 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/28/2006 44 Male 2/21/2007 United States
Primary
Secondary
Concomitant
Oedema Required Intervention 2/15/2007 79 Male 197 lb 2/21/2007 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 12/4/2006 68 Male 220 lb 3/2/2007 United Kingdom
Primary
Concomitant
Somnolence Other Serious 2/2/2007 64 Female 3/2/2007 United Kingdom
Primary
Concomitant
Gastric Ulcer Haemorrhage Hospitalization 2/6/2007 68 Unknown 3/5/2007 United Kingdom
Primary
Concomitant
Somnolence Other Serious 2/2/2006 Male 3/9/2007 Other Health Professional France
Primary
Concomitant
Myositis Other Serious 2/1/2007 64 Female 220 lb 3/14/2007 United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 2/7/2007 71 Male 3/16/2007 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 76 Female 4/9/2007 Consumer Colombia
Primary
Concomitant
Nodal Arrhythmia Hospitalization 58 Male 171 lb 3/1/2007 Pharmacist United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 11/23/2006 69 Male 251 lb 11/30/2006 Pharmacist United States
Primary
Concomitant
Cardiac Valve Disease Other Serious 3/22/2007 Female 5/2/2007 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 4/13/2007 70 Female 5/18/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Drug Ineffective 1/6/2007 71 Male 202 lb 2/28/2007 United States
Primary
Concomitant
Pain In Extremity Other Serious 85 Female 5/22/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/13/2007 70 Female 5/22/2007 United Kingdom
Primary
Secondary
Concomitant
Pain 1/1/2006 Male 2/22/2007 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 4/13/2007 70 Female 5/24/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urticaria Other Serious 1/1/2007 38 Female 4/13/2007 Pharmacist United States
Primary
Concomitant
Death Death 5/20/2007 66 Male 108 lb 6/28/2007 Consumer Brazil
Primary
Concomitant
Wheezing Life Threatening 8/11/2004 Male 7/9/2007 Physician United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 65 Female 152 lb 7/12/2007 Physician Austria
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 Female 152 lb 7/18/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Angina Pectoris Disability 2/1/2007 62 Male 231 lb 8/10/2007 Consumer United Kingdom
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 65 Female 152 lb 8/17/2007 Physician Austria
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 Female 152 lb 8/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 65 Female 152 lb 8/23/2007 Physician Austria
Primary
Secondary
Concomitant
Wound Complication Other Serious 1/1/2006 56 Male 8/28/2007 Physician United States
Primary
Concomitant
Somnolence Other Serious 2/2/2006 Male 8/28/2007 Other Health Professional France
Primary
Concomitant
Wound Complication Other Serious 1/1/2006 56 Male 8/29/2007 Physician United States
Primary
Concomitant
Chest Pain Hospitalization 7/14/2007 65 Female 194 lb 8/30/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Cytomegaloviral Hospitalization 11/22/2004 Female 132 lb 9/21/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypoaesthesia Hospitalization 8/14/2007 69 Male 9/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hypoglycaemia Other Serious 8/29/2007 68 Female 10/9/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 8/29/2007 68 Female 10/9/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Vaginal Haemorrhage Other Serious 8/12/2007 77 Female 132 lb 10/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hypoglycaemia Other Serious 8/29/2007 68 Female 10/5/2007 Philippines
Primary
Secondary
Concomitant
Therapeutic Response Decreased 5/17/2007 60 Female 243 lb 10/24/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 11/29/2005 75 Male 213 lb 10/27/2007 Physician United Kingdom
Primary
Concomitant
Sensory Loss Required Intervention 9/11/2006 83 Female 10/29/2007 Pharmacist United States
Primary
Concomitant
Atrial Fibrillation Other Serious 10/25/2007 Male 11/2/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 44 Male 11/8/2007 Pharmacist Korea, Republic Of
Primary
Concomitant
Hallucination, Auditory Other Serious 6/10/2007 Male 11/12/2007 Physician Switzerland
Primary
Concomitant
Blood Glucose Decreased 8/6/2007 Female 252 lb 11/29/2007 Consumer United States
Primary
Concomitant
Nasopharyngitis 11/23/2007 Male 12/3/2007 Consumer United States
Primary
Concomitant
Nasopharyngitis 11/23/2007 Male 12/5/2007 Consumer United States
Primary
Concomitant
Cardiac Arrest Other Serious 73 Female 12/6/2007 Consumer
Primary
Concomitant
Blood Cholesterol Increased Other Serious 59 Male 187 lb 12/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Coronary Artery Stenosis Hospitalization 72 Male 176 lb 11/14/2007 Israel
Primary
Concomitant
Muscular Weakness Disability 8/24/2007 12/5/2007 United Kingdom
Primary
Secondary
Concomitant
Skin Discolouration 7/1/2007 Female 231 lb 12/14/2007 United States
Primary
Concomitant
Pruritus 8/13/2007 Female 12/14/2007 Physician United States
Primary
Concomitant
Accidental Exposure 9/20/2007 Female 150 lb 12/14/2007 Consumer United States
Primary
Concomitant
Uveitis Other Serious 11/8/2007 Male 12/17/2007 Physician United Kingdom
Primary
Concomitant
Acute Myocardial Infarction Life Threatening 72 Male 176 lb 12/20/2007 Israel
Primary
Concomitant
Inflammation Other Serious 12/3/2007 70 Female 185 lb 12/21/2007 Consumer Brazil
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 52 Female 12/18/2007 Turkey
Primary
Secondary
Concomitant
Acute Myocardial Infarction Life Threatening 72 Male 176 lb 12/31/2007 Israel
Primary
Concomitant
Multiple Myeloma Other Serious 51 Female 309 lb 12/31/2007 Consumer United Kingdom
Primary
Concomitant
Drug Interaction Hospitalization 7/1/2007 77 Female 12/31/2007 Other Health Professional Spain
Primary
Concomitant
Interacting
International Normalised Ratio Increased 10/9/2007 68 Male 11/2/2007 Pharmacist United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 10/14/2007 56 Male 1/10/2008
Primary
Concomitant
Rhabdomyolysis Life Threatening 1/28/2008 68 Male 181 lb 2/4/2008 Physician United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 10/1/2007 59 Female 1/21/2008 Pharmacist United States
Primary
Concomitant
Coronary Artery Occlusion Hospitalization 6/28/2007 80 Male 12/3/2007 Consumer United States
Primary
Concomitant
Nasopharyngitis 11/23/2007 Male 2/12/2008 Consumer United States
Primary
Concomitant
Tremor 2/11/2008 49 Male 218 lb 2/25/2008 United States
Primary
Concomitant
Respiratory Failure Hospitalization 12/19/2007 Female 2/25/2008 Physician Iceland
Primary
Concomitant
Tremor 2/11/2008 49 Male 218 lb 2/27/2008 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 52 Female 2/22/2008 Physician Turkey
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/30/2007 76 Female 103 lb 2/25/2008 France
Primary
Secondary
Concomitant
Productive Cough Other Serious 1/31/2008 71 Male 176 lb 2/29/2008 Physician United Kingdom
Primary
Concomitant
Visual Disturbance Disability 10/1/2007 57 Female 315 lb 3/3/2008 Consumer United Kingdom
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious 1/31/2008 71 Male 176 lb 3/1/2008 United Kingdom
Primary
Concomitant
Rash Pruritic Disability 2/1/2008 71 Female 3/4/2008 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/11/2008 78 Male 3/5/2008 Pharmacist United States
Primary
Concomitant
Orthostatic Hypotension Other Serious 1/31/2008 3/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Tongue Haemorrhage Other Serious 1/14/2008 74 Male 3/6/2008 United Kingdom
Primary
Concomitant
Injection Site Pain 11/25/2007 Male 139 lb 3/15/2008 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 4/13/2007 70 Female 3/13/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Overdose Other Serious 7/24/2007 68 Female 9/7/2007 Physician Philippines
Primary
Secondary
Concomitant
Oral Intake Reduced Other Serious 7/26/2007 68 Female 8/23/2007 Physician Philippines
Primary
Secondary
Concomitant
Tinnitus 76 Male 3/28/2008 Physician United Kingdom
Primary
Concomitant
Multiple Myeloma Other Serious 51 Female 309 lb 4/1/2008 Consumer United Kingdom
Primary
Concomitant
Tremor Other Serious 7/2/2007 79 Male 4/8/2008 Pharmacist United States
Primary
Concomitant
Sudden Death Death 6/10/2007 Male 4/10/2008 Physician New Zealand
Primary
Secondary
Concomitant
Influenza Like Illness Other Serious 3/1/2007 Female 187 lb 4/17/2008 Denmark
Primary
Concomitant
Carpal Tunnel Syndrome Hospitalization 1/8/2007 Female 160 lb 4/18/2008 Physician Hong Kong
Primary
Secondary
Concomitant
Diverticulitis Hospitalization 1/5/2007 Male 210 lb 4/22/2008 Physician United States
Primary
Secondary
Concomitant
Cardiogenic Shock Life Threatening 11/19/2007 64 Male 4/18/2008 Germany
Primary
Concomitant
Blood Glucose Increased Other Serious 51 Male 151 lb 4/29/2008 Other Health Professional United Kingdom
Primary
Concomitant
Diverticulitis Hospitalization 1/5/2007 Male 210 lb 5/2/2008 Physician United States
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 4/28/2008 Female 130 lb 5/6/2008 Consumer Brazil
Primary
Concomitant
Oedema Peripheral Hospitalization 59 5/6/2008 Physician United States
Primary
Concomitant
Skin Reaction Death 1/23/2008 57 Female 5/5/2008 Consumer Japan
Primary
Secondary
Concomitant
Diverticulitis Hospitalization 1/5/2007 Male 210 lb 5/12/2008 Physician United States
Primary
Secondary
Concomitant
Rash Generalised Disability 3/4/2008 72 Male 214 lb 5/8/2008 United Kingdom
Primary
Secondary
Concomitant
Rash Disability 3/4/2008 72 Male 5/9/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rash Generalised Disability 3/4/2008 72 Male 5/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Generalised Disability 3/4/2008 72 Male 5/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Disability 3/4/2008 72 Male 5/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rash Generalised Disability 3/4/2008 72 Male 214 lb 5/20/2008 United Kingdom
Primary
Secondary
Concomitant
Hypertension Other Serious Male 6/2/2008 Consumer Brazil
Primary
Concomitant
Dysphagia Other Serious 3/4/2008 Male 6/3/2008 Physician United Kingdom
Primary
Concomitant
Dysphagia Other Serious 3/4/2008 Male 6/10/2008 Physician United Kingdom
Primary
Concomitant
Oedema Peripheral Hospitalization 59 6/11/2008 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 8/25/2006 59 Male 6/18/2008 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/7/2008 Female 207 lb 6/27/2008 Consumer United Kingdom
Primary
Concomitant
Circulatory Collapse Other Serious 2/21/2008 81 Male 7/9/2008 Consumer Germany
Primary
Concomitant
Nausea Hospitalization 69 Male 139 lb 7/15/2008 Physician Brazil
Primary
Concomitant

Drug Data