Diltiazem combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Syncope Hospitalization 2/7/2005 68 Male 170 lb 10/31/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Disorder Other Serious 79 Male 156 lb 1/20/2006 Physician Canada
Primary
Secondary
Concomitant
Pneumonitis Death 6/1/2005 69 Male 1/30/2006 United Kingdom
Primary
Concomitant
Tachycardia Hospitalization 70 Female 2/6/2006 Physician Australia
Primary
Concomitant
Pneumonitis Death 6/1/2005 69 Male 2/6/2006 United Kingdom
Primary
Concomitant
Overdose Other Serious 75 Male 2/3/2006 Physician France
Primary
Concomitant
Therapy Non-responder Death 46 Female 2/7/2006 Pharmacist United States
Primary
Secondary
Vision Blurred Disability 1/16/2006 65 Female 2/10/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hyperthyroidism Hospitalization 12/1/2005 43 Male 168 lb 2/28/2006 Poland
Primary
Secondary
Concomitant
Catheter Related Complication Life Threatening 9/26/2003 49 Male 181 lb 3/14/2006 Consumer Argentina
Primary
Concomitant
Cerebrovascular Accident Hospitalization 8/10/2005 71 Male 250 lb 12/27/2005 Consumer United States
Primary
Concomitant
Vomiting Other Serious 9/26/2005 71 Female 182 lb 4/13/2006 Pharmacist United States
Primary
Concomitant
Hypotension Hospitalization 2/9/2006 82 Male 3/1/2006 Pharmacist United States
Primary
Secondary
Concomitant
Subdural Haematoma Death 1/28/2006 63 Male 1/31/2006 Pharmacist United States
Primary
Concomitant
Hypernatraemia Other Serious 1/1/2006 69 Male 196 lb 4/19/2006 Physician France
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 69 Female 196 lb 5/1/2006 Physician France
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2003 84 Female 5/9/2006 Australia
Primary
Concomitant
Neutrophil Count Decreased Other Serious 3/14/2006 49 Male 212 lb 5/8/2006 United States
Primary
Concomitant
Tremor Life Threatening 3/9/2006 40 Male 205 lb 3/10/2006 United States
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 1/1/2006 70 Female 5/10/2006 Physician Australia
Primary
Secondary
Concomitant
International Normalised Ratio Increased Disability 3/28/2006 61 Female 5/10/2006 United States
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 1/1/2005 70 Female 5/11/2006 Physician Australia
Primary
Secondary
Concomitant
Lethargy Hospitalization 4/23/2006 77 Male 208 lb 5/15/2006 Pharmacist United States
Primary
Concomitant
Staphylococcal Infection Other Serious 1/1/2006 63 Male 121 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 10/18/2005 59 Male 6/1/2006 Other Health Professional Malaysia
Primary
Concomitant
Wound Infection Hospitalization 62 Male 223 lb 4/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Drug Effect Decreased 1/1/2006 80 Male 150 lb 4/3/2006 Consumer United States
Primary
Concomitant
Renal Failure Acute Required Intervention 2/9/2006 76 Male 150 lb 3/7/2006 Pharmacist United States
Primary
Concomitant
Hepatic Function Abnormal Other Serious 2/21/2005 68 Male 154 lb 5/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Middle Insomnia 12/19/2005 84 Female 4/3/2006 Consumer United States
Primary
Concomitant
Tachycardia Other Serious 3/24/2006 53 Male 5/26/2006 United Kingdom
Primary
Concomitant
Intentional Drug Misuse Other Serious 71 Male 238 lb 4/20/2006 United States
Primary
Concomitant
Thrombocytopenia Life Threatening 5/15/2006 69 Female 6/22/2006 Physician Hong Kong
Primary
Concomitant
Feeling Abnormal 3/2/2006 82 Male 5/19/2006 United States
Primary
Concomitant
Thrombocytopenia Life Threatening 5/15/2006 69 Female 7/14/2006 Physician Hong Kong
Primary
Concomitant
Vomiting Other Serious 53 Male 7/13/2006 United States
Primary
Secondary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Hospitalization 7/5/2006 65 Male 148 lb 7/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Urine Abnormality Hospitalization 72 Female 7/20/2006 Spain
Primary
Secondary
Concomitant
Tenderness Hospitalization 2/1/2000 75 Male 7/21/2006 Other Health Professional Spain
Primary
Secondary
Trigeminal Neuralgia Hospitalization 1/1/2005 52 Female 220 lb 8/11/2006 Physician Germany
Primary
Secondary
Concomitant
Myalgia 5/2/2006 Male 229 lb 8/16/2006 Pharmacist United States
Primary
Concomitant
Pain In Extremity Other Serious 8/3/2006 59 Male 167 lb 8/17/2006 Consumer United States
Primary
Concomitant
Erysipeloid Other Serious 1/1/2006 72 Male 187 lb 8/11/2006 Physician France
Primary
Concomitant
Respiratory Failure Death 6/27/2005 Male 176 lb 9/1/2006 United Kingdom
Primary
Secondary
Concomitant
Culture Urine Positive Hospitalization 9/16/2006 71 Female 10/18/2006 Other Health Professional United Kingdom
Primary
Concomitant
Malaise Other Serious 7/24/2006 72 Female 154 lb 10/30/2006 United Kingdom
Primary
Secondary
Concomitant
Swelling Face Hospitalization 85 Male 11/10/2006 United Kingdom
Primary
Secondary
Concomitant
Skin Lesion Other Serious 7/23/2006 72 Female 11/10/2006 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 80 Female 11/13/2006 Physician New Zealand
Primary
Concomitant
Skin Reaction Other Serious 10/6/2006 62 Female 198 lb 11/27/2006 United Kingdom
Primary
Secondary
Concomitant
Tachycardia Life Threatening 10/2/2006 85 Male 12/18/2006 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/9/2007 80 Male 234 lb 1/12/2007 Pharmacist United States
Primary
Concomitant
Hypertension Other Serious 1/18/2007 Male 1/31/2007 Physician Portugal
Primary
Concomitant
Pneumonia Aspiration Death 2/26/2003 Male 230 lb 2/6/2007 Pharmacist United States
Primary
Concomitant
Interacting
Hypoglycaemia Death 79 Male 231 lb 2/6/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/1/2006 Female 223 lb 2/6/2007 Consumer United States
Primary
Secondary
Concomitant
Feeling Abnormal 3/2/2006 82 Male 11/21/2006 United States
Primary
Concomitant
Subdural Haematoma Life Threatening 1/28/2007 56 Male 2/6/2007 Pharmacist United States
Primary
Secondary
Concomitant
Presyncope Hospitalization 10/16/2006 67 Male 236 lb 1/5/2007 Pharmacist United States
Primary
Secondary
Concomitant
Epistaxis Hospitalization 2/7/2007 74 Male 138 lb 2/12/2007 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 1/30/2007 74 Male 159 lb 2/12/2007 Pharmacist United States
Primary
Concomitant
Polydipsia Psychogenic Hospitalization 10/12/2006 69 Male 2/13/2007 Pharmacist United States
Primary
Secondary
Concomitant
Sinus Tachycardia Death 55 Male 2/13/2007 Physician United States
Primary
Concomitant
Duodenal Ulcer Haemorrhage Life Threatening 11/15/2006 66 Female 2/20/2007 United Kingdom
Primary
Concomitant
Weight Increased Other Serious 4/1/2006 Female 223 lb 3/7/2007 Consumer United States
Primary
Secondary
Concomitant
Lentigo Maligna Stage Unspecified Other Serious 2/16/2007 Male 191 lb 3/14/2007 Physician Australia
Primary
Concomitant
Weight Increased Other Serious 4/1/2006 Female 223 lb 3/16/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 2/22/2007 Female 388 lb 3/23/2007 United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/1/2006 Female 223 lb 3/27/2007 Consumer United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 73 Female 3/20/2007 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 79 Female 3/20/2007 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 2/22/2007 Female 388 lb 3/30/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 2/22/2007 Female 176 lb 4/4/2007 United Kingdom
Primary
Secondary
Concomitant
Dysgeusia 11/4/2006 76 Female 260 lb 1/12/2007 Consumer United States
Primary
Concomitant
Gastrointestinal Carcinoma Required Intervention 4/1/2006 76 Male 4/5/2007 Canada
Primary
Concomitant
Hypersomnia Hospitalization 11/4/2006 61 Male 278 lb 4/12/2007 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 4/1/2006 Female 223 lb 4/20/2007 Consumer United States
Primary
Secondary
Concomitant
Myopathy Required Intervention 72 Female 4/12/2007 Norway
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 4/18/2007 57 Male 194 lb 4/30/2007 Consumer Brazil
Primary
Concomitant
Cough Other Serious 11/21/2006 58 Male 198 lb 11/22/2006 Physician United States
Primary
Concomitant
Toothache 75 Male 185 lb 4/30/2007 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/14/2006 49 Male 212 lb 4/23/2007 United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 69 Male 4/30/2007 Other Health Professional Spain
Primary
Secondary
Concomitant
Respiratory Disorder Other Serious 9/1/2005 79 Male 5/14/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Lymphoid Tissue Hyperplasia Other Serious 1/1/2005 68 Male 5/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Neoplasm Other Serious 3/6/2007 Male 5/11/2007 Brazil
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/14/2006 49 Male 212 lb 5/17/2007 United States
Primary
Concomitant
Sinoatrial Block Other Serious 3/23/2007 47 Male 5/14/2007 Spain
Primary
Secondary
Concomitant
Haematoma Other Serious 5/1/2007 78 Female 5/31/2007 Physician France
Primary
Concomitant
Middle Insomnia 1/1/2006 75 Female 170 lb 4/12/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/14/2006 49 Male 212 lb 5/31/2007 United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2006 6/7/2007 Consumer United States
Primary
Concomitant
Vasospasm Hospitalization 84 Female 6/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Disability 3/21/2007 71 Female 6/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Stomatitis 2/1/2007 59 Female 92 lb 6/22/2007 Consumer United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization Female 7/3/2007 Physician United Kingdom
Primary
Concomitant
Sinus Bradycardia Life Threatening 84 Female 7/6/2007 Germany
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 8/14/2006 67 Male 7/13/2007 United Kingdom
Primary
Concomitant
Pain Hospitalization 7/10/2006 47 Male 154 lb 7/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Haemorrhage Required Intervention 6/27/2007 84 Male 153 lb 7/18/2007 Pharmacist United States
Primary
Concomitant
Sinus Operation 3/1/2006 Male 7/23/2007 Consumer United States
Primary
Concomitant
Dizziness 73 Female 7/23/2007 Consumer United States
Primary
Concomitant
Sinus Bradycardia Life Threatening 84 Female 7/17/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 8/14/2006 67 Male 7/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 7/20/2007 Male 8/2/2007 Consumer United Kingdom
Primary
Concomitant
Troponin T Increased Life Threatening 4/3/2007 48 Female 165 lb 8/10/2007 Physician Philippines
Primary
Concomitant
Sepsis Other Serious 6/13/2007 Male 117 lb 8/21/2007 Other Health Professional Brazil
Primary
Secondary
Concomitant
Cardiac Murmur Hospitalization 7/1/2007 74 Female 176 lb 8/21/2007 United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 2/23/2007 Male 302 lb 8/24/2007 Physician United States
Primary
Concomitant
Staphylococcal Scalded Skin Syndrome Hospitalization 5/8/2007 55 Male 8/23/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 6/13/2007 Male 117 lb 8/31/2007 Other Health Professional Brazil
Primary
Secondary
Concomitant
Hypotension Life Threatening 7/18/2007 47 Female 126 lb 10/5/2007 Physician United States
Primary
Secondary
Concomitant
Rash Maculo-papular Hospitalization 9/13/2007 65 Female 10/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interstitial Lung Disease Other Serious 10/10/2007 Other Health Professional Australia
Primary
Concomitant
Optic Ischaemic Neuropathy Other Serious 76 Male 10/12/2007 Singapore
Primary
Concomitant
Drug Withdrawal Syndrome Other Serious 8/14/2006 67 Male 10/9/2007 United Kingdom
Primary
Concomitant
Interstitial Lung Disease Other Serious 74 Female 10/11/2007 Physician Australia
Primary
Concomitant
Insomnia 1/1/2007 88 Female 122 lb 10/5/2007 Consumer United States
Primary
Concomitant
Insomnia 7/13/2007 89 Female 107 lb 10/5/2007 Consumer United States
Primary
Concomitant
Meningitis Aseptic Hospitalization 62 Male 10/25/2007
Primary
Secondary
Concomitant
Head Banging Hospitalization Male 10/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Extrasystoles Life Threatening 7/18/2007 47 Female 126 lb 10/26/2007 Physician United States
Primary
Secondary
Concomitant
Left Ventricular Failure Other Serious 9/9/2007 Male 11/6/2007 Physician Australia
Primary
Concomitant
Nausea Life Threatening 7/18/2007 47 Female 11/6/2007 United States
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 8/24/2005 70 Male 11/8/2007 Physician France
Primary
Concomitant
Jaundice Other Serious 10/5/2007 56 Female 227 lb 11/15/2007
Primary
Concomitant
Head Banging Hospitalization 10/12/2007 Male 159 lb 11/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatitis Other Serious 10/5/2007 56 Female 227 lb 11/16/2007 United Kingdom
Primary
Concomitant
Tenosynovitis Other Serious 62 Male 11/28/2007 Pharmacist Canada
Primary
Concomitant
Nasopharyngitis 11/23/2007 Male 12/3/2007 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 64 Male 12/5/2007 United States
Primary
Secondary
Concomitant
Nasopharyngitis 11/23/2007 Male 12/5/2007 Consumer United States
Primary
Concomitant
Rectal Cancer Metastatic Hospitalization 6/1/2007 87 Male 143 lb 11/30/2007 Consumer Germany
Primary
Concomitant
Syncope Hospitalization 10/12/2007 Male 159 lb 12/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 1/1/2007 77 Male 12/17/2007 Physician Canada
Primary
Concomitant
Syncope Other Serious 1/1/2007 Male 200 lb 12/19/2007 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 12/10/2007 80 Male 172 lb 12/20/2007 Physician Canada
Primary
Concomitant
Vomiting Hospitalization 6/1/2007 87 Male 143 lb 12/14/2007 Consumer Germany
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/14/2007 85 Female 12/18/2007 Physician United States
Primary
Secondary
Concomitant
Knee Arthroplasty Hospitalization 7/1/2007 Female 1/3/2008 Consumer Brazil
Primary
Concomitant
Rhabdomyolysis Disability 6/12/2007 86 Female 171 lb 1/9/2008 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 64 Male 1/21/2008 Other Health Professional United States
Primary
Secondary
Rhabdomyolysis Hospitalization 64 Male 259 lb 1/25/2008 United States
Primary
Secondary
Concomitant
Hypotension Life Threatening 7/18/2007 47 Female 126 lb 2/6/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/1/2007 58 Female 152 lb 2/7/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 10/1/2007 59 Female 1/21/2008 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 1/1/2005 52 Female 170 lb 2/11/2008 Other Health Professional United States
Primary
Concomitant
Nasopharyngitis 11/23/2007 Male 2/12/2008 Consumer United States
Primary
Concomitant
Respiratory Failure Hospitalization 11/8/2007 77 Female 117 lb 2/14/2008 Pharmacist United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 11/8/2007 78 Female 2/14/2008 Other Health Professional United Kingdom
Primary
Concomitant

Drug Data