Quinine Sulfate combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Other Serious 12/12/2005 78 Male 151 lb 12/30/2005 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 3/1/2005 70 Male 2/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Headache Other Serious 1/31/2006 77 Male 199 lb 1/31/2006 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 3/1/2005 70 Male 2/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Psychotic Disorder 10/19/2005 74 Male 160 lb 11/1/2005 Pharmacist United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Required Intervention 4/18/2006 77 Male 134 lb 4/18/2006 Pharmacist United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 5/19/2006 81 Male 110 lb 7/14/2006 Pharmacist United States
Primary
Concomitant
Rash Hospitalization 5/29/2006 81 Male 243 lb 7/14/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 5/1/2006 69 Female 7/20/2006 Physician
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/1/2006 69 Female 8/1/2006 Physician
Primary
Secondary
Concomitant
Hypertension Other Serious 1/1/2000 73 Male 217 lb 7/19/2006 Consumer United Kingdom
Primary
Concomitant
Spinal Fracture Hospitalization 3/30/2005 Female 190 lb 8/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 7/25/2006 67 Male 8/7/2006 Physician United Kingdom
Primary
Concomitant
Skin Fissures Disability 1/1/2006 49 Female 8/3/2006 Physician United States
Primary
Concomitant
Poor Quality Drug Administered Other Serious 7/9/2006 77 Female 8/2/2006 United States
Primary
Concomitant
Therapeutic Response Decreased 11/1/2005 Male 143 lb 8/9/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 7/25/2006 67 Male 8/18/2006 Physician United Kingdom
Primary
Concomitant
Sepsis Life Threatening 12/26/2005 63 Female 99 lb 8/29/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/10/2005 85 Female 8/25/2006 United Kingdom
Primary
Secondary
Concomitant
Poor Quality Drug Administered Other Serious 7/9/2006 77 Female 8/28/2006 United States
Primary
Concomitant
Sepsis Life Threatening 12/26/2005 63 Female 99 lb 9/5/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/10/2005 85 Female 8/28/2006 United Kingdom
Primary
Secondary
Concomitant
Helicobacter Infection Hospitalization 1/10/2005 85 Female 8/28/2006 United Kingdom
Primary
Secondary
Concomitant
Sepsis Life Threatening 12/26/2005 63 Female 99 lb 8/29/2006 United Kingdom
Primary
Secondary
Concomitant
Pneumonia Staphylococcal Other Serious 63 Female 99 lb 8/31/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Life Threatening 63 Female 8/29/2006 United Kingdom
Primary
Secondary
Concomitant
Oesophageal Ulcer Other Serious 3/2/2006 77 Female 9/5/2006 United Kingdom
Primary
Concomitant
Sepsis Other Serious 63 Female 99 lb 9/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 8/24/2006 Male 185 lb 9/6/2006 Pharmacist United States
Primary
Concomitant
Sepsis Other Serious 63 Female 99 lb 9/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 1/13/2006 Male 9/12/2006 Pharmacist United States
Primary
Concomitant
Abdominal Discomfort Other Serious 7/10/2006 78 Male 180 lb 7/10/2006 Pharmacist United States
Primary
Concomitant
Skin Oedema Hospitalization 76 Male 9/21/2006 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 9/27/2006 Male 10/23/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 5/1/2006 69 Female 10/27/2006 Physician
Primary
Concomitant
Drug Ineffective Hospitalization 82 Male 10/30/2006 Consumer United States
Primary
Concomitant
Lethargy Hospitalization 5/1/2006 69 Female 11/9/2006 Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/29/2006 71 Female 11/30/2006
Primary
Concomitant
Sepsis Syndrome Required Intervention 5/31/2006 70 Female 12/15/2006 Pharmacist United States
Primary
Concomitant
Skin Oedema Hospitalization 76 Male 12/14/2006 Other Health Professional United States
Primary
Concomitant
Sepsis Other Serious 63 Female 99 lb 12/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Waist Circumference Increased Hospitalization 1/22/2007 82 Male 196 lb 2/6/2007 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/21/2007 Male 230 lb 2/9/2007 Consumer United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 1/22/2007 82 Male 196 lb 2/13/2007 Physician United States
Primary
Concomitant
Gynaecomastia Other Serious 1/29/2007 Male 212 lb 2/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Waist Circumference Increased Hospitalization 1/22/2007 82 Male 3/1/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Fatigue 1/1/2005 50 Female 143 lb 1/23/2007 Consumer United States
Primary
Concomitant
Nightmare Other Serious 1/1/1999 68 Male 4/10/2007 Consumer United Kingdom
Primary
Concomitant
Fatigue Other Serious Male 146 lb 5/3/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 5/1/2006 73 Male 5/10/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Death Other Serious 3/5/2007 Male 154 lb 5/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Insomnia Other Serious 3/15/2007 6/7/2007 Consumer United Kingdom
Primary
Concomitant
Blood Bilirubin Increased Other Serious 3/5/2007 79 Male 6/14/2007 United Kingdom
Primary
Secondary
Concomitant
Blood Bilirubin Increased Death 3/5/2007 79 Male 6/13/2007 United Kingdom
Primary
Secondary
Urticaria Other Serious 3/28/2007 74 Male 7/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 6/8/2006 Female 157 lb 7/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vision Blurred Required Intervention 8/15/2007 68 Male 9/7/2007 United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 7/2/2007 82 Female 9/7/2007 United Kingdom
Primary
Concomitant
Urinary Tract Infection Life Threatening 1/1/2007 73 Female 154 lb 9/21/2007 United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Life Threatening 1/1/2007 73 Female 9/21/2007 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 73 Female 9/15/2007 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 73 Female 9/26/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 73 Male 10/22/2007 Consumer United Kingdom
Primary
Concomitant
Sleep Disorder Hospitalization 6/1/2005 62 Male 10/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sleep Disorder Hospitalization 6/1/2005 62 Male 10/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 9/12/2007 67 Female 170 lb 10/30/2007 Consumer United Kingdom
Primary
Concomitant
Head Banging Hospitalization Male 10/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sleep Disorder Hospitalization 6/1/2005 62 Male 11/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Head Banging Hospitalization 10/12/2007 Male 159 lb 11/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 10/12/2007 Male 159 lb 12/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Peritonitis Bacterial 11/23/2007 75 Male 12/19/2007 Canada
Primary
Concomitant
Peritonitis Bacterial 11/23/2007 75 Male 12/27/2007 Canada
Primary
Concomitant
Pulmonary Embolism Death 2/4/2008 Female 2/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
Productive Cough Disability Female 213 lb 3/4/2008 Physician United Kingdom
Primary
Concomitant
Torsade De Pointes Hospitalization 2/8/2008 79 Female 3/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 2/4/2008 Female 4/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Cardio-respiratory Arrest Death 4/10/2008 69 Female 207 lb 4/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 2/4/2008 Female 5/19/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 2/4/2008 Female 8/8/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Paranoia Hospitalization 9/14/2008 70 Female 10/13/2008 Other Health Professional France
Primary
Concomitant
Off Label Use 75 Female 200 lb 11/20/2008 United States
Primary
Concomitant
Confusional State Hospitalization 2/16/2009 Female 178 lb 3/9/2009 Other Health Professional United States
Primary
Concomitant
Tendon Disorder Other Serious 1/1/2005 72 Female 139 lb 3/9/2009 Physician United States
Primary
Concomitant
Tendon Disorder Other Serious 1/1/2005 72 Female 139 lb 3/26/2009 Physician United States
Primary
Concomitant
Tendon Disorder Other Serious 1/1/2005 72 Female 139 lb 3/31/2009 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2008 Female 161 lb 4/2/2009 Other Health Professional United States
Primary
Concomitant
Palpitations Hospitalization 73 Female 5/28/2009 United States
Primary
Concomitant
Vomiting Hospitalization 73 Female 6/30/2009 United States
Primary
Concomitant
Musculoskeletal Stiffness Hospitalization 6/4/2009 78 Female 7/15/2009
Primary
Concomitant
Vomiting Hospitalization 73 Female 7/14/2009 United States
Primary
Concomitant
Palpitations Hospitalization 70 Female 7/19/2009 Lawyer United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 8/10/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/13/2009 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/23/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 70 Female 8/28/2009 United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 70 Female 9/3/2009 United States
Primary
Concomitant
Underdose Hospitalization 6/1/2009 Male 9/10/2009 Consumer United States
Primary
Concomitant
Pancreatitis Other Serious 3/30/2001 48 Male 265 lb 9/23/2009 United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 9/17/2009 United States
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 4/27/2009 70 Female 114 lb 10/14/2009 Other Health Professional United States
Primary
Concomitant
Pancreatitis Hospitalization 9/6/2009 58 Male 11/10/2009
Primary
Concomitant
Pain In Extremity 2/25/2009 Male 12/23/2009 Other Health Professional United States
Primary
Concomitant
Syncope Hospitalization 85 Male 12/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 2/24/2009 Female 1/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Other Serious 2/24/2009 Female 1/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Nightmare Other Serious 8/8/2008 85 Male 1/20/2010 Other Health Professional Italy
Primary
Concomitant
Pain Hospitalization 5/27/2008 Male 316 lb 2/1/2010 Physician United States
Primary
Concomitant
Pain Hospitalization 5/27/2008 Male 316 lb 2/10/2010 Physician United States
Primary
Concomitant
Tooth Infection Other Serious 8/1/2008 Male 311 lb 2/10/2010 United States
Primary
Concomitant
Death Other Serious 3/5/2007 79 Male 2/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Death 76 Male 159 lb 2/17/2010 Pharmacist United Kingdom
Primary
Concomitant
Underdose Hospitalization 6/1/2009 Male 3/2/2010 Physician United States
Primary
Concomitant
Erectile Dysfunction Other Serious 1/1/2010 70 Male 238 lb 3/19/2010 Other Health Professional United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/18/2008 85 Male 3/26/2010 Lawyer United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 89 Female 3/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious Male 222 lb 5/10/2010 Other Health Professional United States
Primary
Concomitant
Bronchopneumonia Hospitalization 4/1/2010 85 5/12/2010 Other Health Professional Switzerland
Primary
Concomitant
Pelvic Fracture Hospitalization 9/11/2009 81 Female 5/18/2010 Physician United Kingdom
Primary
Concomitant
Myocardial Ischaemia Hospitalization 78 Male 222 lb 5/19/2010 Other Health Professional United States
Primary
Concomitant
Myocardial Ischaemia Death 1/13/2010 73 Female 6/11/2010 Other Health Professional United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/18/2008 85 Male 185 lb 6/15/2010 Other Health Professional United States
Primary
Concomitant
Pelvic Fracture Hospitalization 9/11/2009 81 Female 6/29/2010 Physician United Kingdom
Primary
Concomitant
Idiopathic Thrombocytopenic Purpura Hospitalization 10/1/2002 50 Female 355 lb 7/9/2010 United States
Primary
Concomitant
X-ray Abnormal Other Serious 1/1/1998 52 Female 8/5/2010 United States
Primary
Secondary
Concomitant
Myocardial Ischaemia Death 1/13/2010 73 Female 8/6/2010 Other Health Professional United Kingdom
Primary
Concomitant
Tendon Rupture Hospitalization 12/1/2009 70 Male 187 lb 8/17/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Tendon Rupture Disability 5/1/2010 70 Male 187 lb 8/19/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/1/1998 52 Female 8/20/2010 United States
Primary
Secondary
Concomitant
Tendon Rupture Other Serious 5/1/2010 70 Male 187 lb 8/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tendon Rupture Disability 5/1/2010 70 Male 187 lb 8/18/2010
Primary
Secondary
Concomitant
Tendon Rupture Disability 5/1/2010 70 Male 187 lb 8/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tendon Rupture Other Serious 5/1/2010 71 Male 187 lb 8/27/2010 United Kingdom
Primary
Secondary
Concomitant
Nausea Hospitalization 8/8/2010 81 Male 9/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Tendon Rupture Disability 5/1/2010 70 Male 187 lb 9/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nausea Hospitalization 8/8/2010 81 Male 9/3/2010 Other Health Professional United Kingdom
Primary
Concomitant
Nausea Hospitalization 8/8/2010 81 Male 9/6/2010 Other Health Professional United Kingdom
Primary
Concomitant
Cerebrovascular Accident Hospitalization 7/18/2010 61 Male 247 lb 9/22/2010 Other Health Professional Switzerland
Primary
Concomitant
X-ray Abnormal Other Serious 1/1/1998 52 Female 9/29/2010 United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 9/9/2010 63 Female 10/7/2010 Pharmacist United Kingdom
Primary
Concomitant
X-ray Abnormal Other Serious 1/1/1998 52 Female 11/9/2010 United States
Primary
Secondary
Concomitant
Visual Impairment Required Intervention 1/1/2007 67 Female 11/8/2010 Lawyer United States
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 2/13/2008 66 Male 210 lb 11/5/2010 Lawyer United States
Primary
Concomitant
X-ray Abnormal Other Serious 1/25/1998 52 Female 11/29/2010 United States
Primary
Secondary
Concomitant
Rash Generalised Other Serious 1/1/2010 11/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
Tendon Rupture Other Serious 5/1/2010 71 Male 187 lb 12/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2007 36 Female 12/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tendon Rupture Other Serious 5/1/2010 70 Male 187 lb 12/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Paranoia Other Serious 1/1/2010 57 Female 128 lb 12/16/2010 Physician United Kingdom
Primary
Concomitant
X-ray Abnormal Other Serious 1/25/1998 52 Female 12/21/2010 United States
Primary
Secondary
Concomitant
Tendon Rupture Other Serious 5/21/2010 71 Male 187 lb 12/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant

Drug Data