Simvastatin combined with Tegretol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Convulsion Life Threatening 12/17/2005 53 Male 1/13/2006 United Kingdom
Primary
Concomitant
Dysphagia Disability 11/1/2005 86 Male 174 lb 1/23/2006 Pharmacist United Kingdom
Primary
Concomitant
Tetany Other Serious 12/5/2005 66 Female 141 lb 1/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tetany Other Serious 12/5/2005 66 Female 141 lb 1/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Insomnia 10/19/2005 80 Male 3/7/2006 Consumer United States
Primary
Concomitant
Insomnia 10/19/2005 80 Male 3/7/2006 Consumer United States
Primary
Concomitant
Vomiting Other Serious 5/1/2006 65 Female 6/16/2006 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 5/17/2006 65 Female 6/22/2006 United Kingdom
Primary
Secondary
Concomitant
Angioneurotic Oedema Other Serious 74 Male 7/13/2006 United Kingdom
Primary
Secondary
Concomitant
Thinking Abnormal 5/1/2006 64 Male 200 lb 7/12/2006 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 9/1/2004 52 Male 150 lb 8/23/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/26/2006 72 Male 11/28/2006 Pharmacist United Kingdom
Primary
Concomitant
Hypertensive Crisis Hospitalization Female 12/15/2006 Physician Germany
Primary
Secondary
Concomitant
Vision Blurred Other Serious 10/1/2006 47 Male 215 lb 12/22/2006 Physician Germany
Primary
Concomitant
Suicide Attempt Hospitalization Male 1/10/2007 Physician Germany
Primary
Secondary
Spinal Epidural Haemorrhage Other Serious 11/30/2006 Female 1/22/2007 Physician Norway
Primary
Secondary
Concomitant
Interacting
Spinal Epidural Haemorrhage Other Serious 11/30/2006 80 Female 1/22/2007 Norway
Primary
Secondary
No Adverse Effect 6/1/2006 69 Male 1/29/2007 Physician United Kingdom
Primary
Concomitant
Spinal Epidural Haemorrhage Other Serious 11/30/2006 Female 1/30/2007 Physician Norway
Primary
Interacting
Urinary Tract Infection Other Serious 11/30/2006 80 Female 1/30/2007 Norway
Primary
Secondary
Myopathy Other Serious 65 Male 3/24/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Convulsion Other Serious 2/25/2007 65 Female 94 lb 4/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Paraesthesia Other Serious 12/1/2006 68 Female 165 lb 4/11/2007 Other Health Professional United States
Primary
Concomitant
Malaise Hospitalization 2/16/2007 74 Female 187 lb 4/23/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 1/1/2007 Male 187 lb 5/1/2007 Germany
Primary
Concomitant
Tracheostomy Other Serious 43 Male 5/7/2007 Physician Brazil
Primary
Secondary
Concomitant
Infection Hospitalization 3/15/2007 70 Male 7/3/2007 Other Health Professional Sweden
Primary
Concomitant
Infection Hospitalization 3/15/2007 70 Male 7/3/2007 Other Health Professional Sweden
Primary
Concomitant
Pancytopenia Required Intervention 2/20/2007 80 Male 131 lb 6/20/2007 Pharmacist United States
Primary
Concomitant
Wound Infection Other Serious 1/1/2001 66 Male 183 lb 8/16/2007 Consumer Brazil
Primary
Concomitant
Weight Increased 57 Female 172 lb 9/17/2007 Consumer United States
Primary
Concomitant
Trigeminal Neuralgia Hospitalization 6/26/2007 57 Female 9/28/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 8/1/2007 62 Female 139 lb 10/5/2007 Consumer Brazil
Primary
Concomitant
Vomiting Life Threatening 4/30/2007 66 Male 10/2/2007 Other Health Professional Norway
Primary
Concomitant
Vomiting Life Threatening 4/30/2007 66 Male 10/22/2007 Norway
Primary
Concomitant
Epilepsy Other Serious 39 Male 11/21/2007 Other Health Professional Germany
Primary
Concomitant
Epilepsy Other Serious 39 Male 11/19/2007 United Kingdom
Primary
Concomitant
Epilepsy Other Serious 11/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Epilepsy Other Serious 39 Male 229 lb 11/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Epilepsy Other Serious 39 Male 11/26/2007 United Kingdom
Primary
Concomitant
Pyrexia Disability 11/3/2007 67 Male 132 lb 12/7/2007 Physician Japan
Primary
Concomitant
Peripheral Motor Neuropathy Hospitalization 12/1/2007 52 Male 198 lb 12/6/2007 Other Health Professional United States
Primary
Concomitant
Medication Error Hospitalization 8/20/2007 78 Female 12/18/2007
Primary
Concomitant
Pyrexia 11/3/2007 67 Male 132 lb 1/4/2008 Physician Japan
Primary
Concomitant
Nausea Other Serious 1/1/2008 Male 2/9/2008 Physician Germany
Primary
Concomitant
Nausea Other Serious 1/1/2008 83 Male 187 lb 3/5/2008 Physician Germany
Primary
Concomitant
Vomiting Other Serious 4/22/2008 Female 5/27/2008
Primary
Concomitant
Prostate Cancer Other Serious 7/1/2007 Male 5/28/2008 Consumer Brazil
Primary
Concomitant
Visual Acuity Reduced Other Serious 80 Male 163 lb 7/28/2008 Consumer Brazil
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/1/2008 55 Male 8/27/2008 Physician France
Primary
Concomitant
Headache Hospitalization 6/1/2008 Male 176 lb 9/9/2008 Consumer United States
Primary
Concomitant
Myocardial Infarction Death 8/13/2008 Male 320 lb 9/23/2008 Physician
Primary
Concomitant
Wrong Drug Administered Other Serious 11/1/2007 75 Female 148 lb 11/10/2008 Consumer Brazil
Primary
Concomitant
Wound Infection Other Serious 1/1/2001 66 Male 183 lb 11/14/2008 Consumer Brazil
Primary
Concomitant
Wrong Drug Administered Other Serious 11/1/2007 75 Female 148 lb 12/8/2008 Consumer Brazil
Primary
Concomitant
Vomiting Required Intervention 1/1/2008 58 Female 205 lb 12/2/2008 Consumer United States
Primary
Concomitant
Orthostatic Hypotension Other Serious Male 12/19/2008 France
Primary
Secondary
Concomitant
Angina Pectoris Other Serious 9/1/2008 64 Male 1/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Tardive Dyskinesia 52 Male 212 lb 1/13/2009 Consumer United States
Primary
Concomitant
Orthostatic Hypotension Other Serious Male 1/16/2009 France
Primary
Secondary
Concomitant
Vomiting Other Serious 4/22/2008 Female 2/2/2009
Primary
Concomitant
Hallucination Other Serious 1/27/2009 85 Male 2/16/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Angina Pectoris Other Serious 9/1/2008 64 Male 2/19/2009 Other Health Professional United Kingdom
Primary
Concomitant
Road Traffic Accident Other Serious 55 Female 117 lb 2/23/2009 Consumer Brazil
Primary
Concomitant
Vertigo Other Serious 3/16/2007 79 Female 148 lb 2/26/2009 Austria
Primary
Secondary
Concomitant
Scar Other Serious 49 Female 150 lb 3/27/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2002 40 Male 4/3/2009 Denmark
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2002 40 Male 243 lb 4/15/2009 Other Health Professional Denmark
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 2/1/2009 73 Female 4/29/2009 Physician Sweden
Primary
Secondary
Concomitant
Visual Impairment Other Serious 1/1/2006 Male 5/21/2009 Consumer Brazil
Primary
Secondary
Concomitant
Road Traffic Accident Other Serious 55 Female 117 lb 6/3/2009 Consumer Brazil
Primary
Concomitant
Uraemic Encephalopathy Other Serious 52 Male 6/27/2009 Physician Brazil
Primary
Concomitant
Vomiting Other Serious 6/4/2009 Male 161 lb 7/8/2009 Pharmacist United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 9/27/2000 49 Female 200 lb 7/13/2009 United States
Primary
Concomitant
Pain In Extremity Other Serious 4/30/2009 Female 139 lb 7/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pollakiuria Other Serious 3/1/2009 Female 154 lb 8/12/2009 Consumer Brazil
Primary
Secondary
Concomitant
Diabetic Neuropathy Other Serious 5/9/2006 49 Female 210 lb 8/13/2009 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2009 Female 155 lb 8/13/2009 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2002 40 Male 243 lb 9/3/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2006 Female 303 lb 9/18/2009 Consumer United States
Primary
Concomitant
Visual Impairment Other Serious 1/1/2009 53 Female 104 lb 9/24/2009 Consumer Brazil
Primary
Secondary
Concomitant
Sepsis Hospitalization 77 Female 9/23/2009 Consumer Brazil
Primary
Concomitant
Visual Impairment Other Serious 1/1/2008 53 Female 104 lb 10/2/2009 Consumer Brazil
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious 12/29/2006 59 Male 303 lb 10/8/2009 United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 1/1/2008 53 Female 104 lb 10/8/2009 Consumer Brazil
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/1/2009 21 Male 132 lb 2/1/2010 Consumer United States
Primary
Concomitant
Tachycardia Other Serious 7/1/2009 Female 141 lb 2/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Overdose Other Serious 1/12/2010 63 Male 198 lb 2/15/2010 Physician Ireland
Primary
Concomitant
Tachycardia Hospitalization 8/1/2009 64 Female 141 lb 3/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 6/1/2009 Female 141 lb 3/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Hospitalization 2/21/2010 Male 279 lb 3/16/2010 Other Health Professional United States
Primary
Concomitant
Tobacco User Other Serious 7/1/2009 Female 141 lb 3/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 4/30/2009 Female 139 lb 3/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urticaria Life Threatening Male 175 lb Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2010 61 Female 4/15/2010 Other Health Professional Spain
Primary
Concomitant
Tremor Hospitalization 2/21/2010 60 Male 279 lb 4/14/2010 Other Health Professional United States
Primary
Concomitant
Mental Status Changes Hospitalization 4/25/2010 64 Male 204 lb 4/29/2010 Pharmacist United States
Primary
Concomitant
Syncope Other Serious 1/1/2005 48 Female 5/3/2010 Consumer Brazil
Primary
Concomitant
Renal Failure Other Serious 7/19/2007 70 Male 5/19/2010 Physician Germany
Primary
Concomitant
Renal Impairment Other Serious 1/1/2006 66 Male 6/3/2010 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 1/1/2006 66 Male 6/22/2010 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/7/2010 64 Male 130 lb 7/12/2010 Consumer United States
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Other Serious 6/1/2010 77 Male 7/13/2010 Other Health Professional Belgium
Primary
Concomitant
Pyrexia Life Threatening 5/8/2010 74 Female 8/2/2010 Physician Switzerland
Primary
Secondary
Concomitant
Muscle Atrophy Other Serious 1/1/2008 70 Male 154 lb 8/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Muscle Atrophy Other Serious 1/1/2008 Male 154 lb 8/3/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Muscle Atrophy Other Serious 1/1/2008 70 Male 154 lb 7/29/2010 Other Health Professional
Primary
Concomitant
Muscle Atrophy Other Serious 1/1/2008 154 lb 7/29/2010 United Kingdom
Primary
Concomitant
Vision Blurred 1/1/2009 47 Female 150 lb 8/3/2010 Consumer United States
Primary
Concomitant
Muscle Atrophy Other Serious 1/1/2008 Male 154 lb 7/30/2010 Other Health Professional United Kingdom
Primary
Concomitant
Fibromyalgia Other Serious Female 274 lb 8/13/2010 Consumer United States
Primary
Secondary
Fibromyalgia Other Serious Female 274 lb 8/17/2010 Consumer United States
Primary
Secondary
Fibromyalgia Other Serious Female 274 lb 8/20/2010 Consumer United States
Primary
Secondary
Fibromyalgia Other Serious 43 Female 274 lb 8/18/2010 United States
Primary
Secondary
Fibromyalgia Other Serious 43 Female 8/27/2010 Consumer United States
Primary
Secondary
Fibromyalgia Other Serious Female 275 lb 8/24/2010 United States
Primary
Secondary
Fibromyalgia Other Serious Female 274 lb 8/24/2010 Consumer United States
Primary
Secondary
Type 2 Diabetes Mellitus Other Serious 1/1/1997 46 Female 200 lb 8/30/2010 United States
Primary
Concomitant
Fibromyalgia Other Serious 43 Female 273 lb 8/30/2010 Consumer United States
Primary
Concomitant
Fibromyalgia Other Serious 8/6/2010 43 Female 273 lb 8/31/2010 Consumer United States
Primary
Secondary
Fibromyalgia Other Serious 9/1/2010 Consumer United States
Primary
Secondary
Fibromyalgia Other Serious 43 Female 274 lb 9/1/2010 Consumer
Primary
Secondary
Fibromyalgia Other Serious 43 Female 274 lb 8/30/2010 Consumer United States
Primary
Concomitant
Fibromyalgia Other Serious 43 Female 274 lb 9/2/2010 Consumer United States
Primary
Secondary
Fibromyalgia Other Serious 8/1/2010 43 Female 274 lb 9/3/2010 Consumer United States
Primary
Secondary
Fibromyalgia Other Serious 43 Female 274 lb 9/7/2010 Consumer United States
Primary
Secondary
Concomitant
Fibromyalgia Other Serious 1/1/2010 43 Female 274 lb 9/2/2010 United States
Primary
Secondary
Fibromyalgia Other Serious 43 Female 274 lb 9/2/2010 United States
Primary
Secondary
Fibromyalgia Other Serious 43 Female 274 lb 9/9/2010 Consumer United States
Primary
Secondary
Concomitant
Fibromyalgia Other Serious 43 Female 9/10/2010 Consumer United States
Primary
Secondary
Weight Increased Other Serious 1/1/2009 67 Female 155 lb 9/16/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 6/30/2010 87 Male 160 lb 9/17/2010 Physician United States
Primary
Concomitant
Suicide Attempt Other Serious Female 185 lb 9/20/2010 Consumer United States
Primary
Concomitant
Grand Mal Convulsion Other Serious 1/1/2009 57 Female 134 lb 9/24/2010 Physician United States
Primary
Concomitant
Skin Lesion Female 10/1/2010 Consumer United States
Primary
Secondary
Concomitant
Off Label Use Other Serious 9/1/2008 64 Male 10/6/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pain Hospitalization 10/7/2010 47 Female 10/26/2010 Other Health Professional Brazil
Primary
Concomitant
Dysphonia 68 Female 10/13/2010 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 10/1/2010 42 Male 213 lb 11/1/2010 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Death 1/13/2004 43 Male 11/18/2010 Other Health Professional United States
Primary
Concomitant
Weight Loss Poor Other Serious 1/1/2009 49 Male 254 lb 11/18/2010 Physician United States
Primary
Secondary
Concomitant
Insomnia 46 Male 11/19/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2009 67 Female 155 lb 8/13/2009 Consumer United States
Primary
Concomitant
Tremor Disability 12/25/2010 84 Male 198 lb 1/21/2011 Other Health Professional United Kingdom
Primary
Concomitant
Overdose Other Serious 1/1/1999 29 Male 1/31/2011 Consumer Norway
Primary
Concomitant
Headache 1/1/2010 62 Female 2/8/2011 Other Health Professional United States
Primary
Concomitant
Drug Interaction Hospitalization 9/10/2010 74 Female 3/4/2011 Other Health Professional Spain
Primary
Concomitant
Interacting
Headache 1/1/2010 62 Female 3/16/2011 Other Health Professional United States
Primary
Concomitant
Fibromyalgia Other Serious Female 273 lb 3/22/2011 Consumer United States
Primary
Secondary
Convulsion Other Serious Female 273 lb 3/28/2011 Consumer United States
Primary
Secondary

Drug Data