Arava combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Peripheral Embolism Other Serious 12/15/2004 Female 1/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hepatotoxicity Hospitalization 1/30/2006 71 Female 3/10/2006 Pharmacist United Kingdom
Primary
Concomitant
Rash Other Serious 72 Female 3/22/2006 Consumer United Kingdom
Primary
Concomitant
Vomiting Life Threatening 66 Male 6/2/2006
Primary
Concomitant
Psoriasis Hospitalization 7/5/2005 57 Male 12/12/2006 Other Health Professional Denmark
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/1/2007 Female 115 lb 6/29/2007 Physician United States
Primary
Concomitant
Myocardial Infarction Life Threatening 5/31/2007 70 Female 132 lb 7/11/2007
Primary
Concomitant
Vomiting Hospitalization 6/22/2007 Female 243 lb 7/23/2007 Physician United States
Primary
Concomitant
Staphylococcal Scalded Skin Syndrome Hospitalization 5/8/2007 55 Male 8/23/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 2/1/2005 Female 9/13/2007 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 8/1/2006 Female 187 lb 9/25/2007 Physician United States
Primary
Concomitant
Gastroenteritis Norwalk Virus Hospitalization 1/1/2007 Female 161 lb 9/28/2007 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Other Serious Male 12/20/2007 Physician
Primary
Concomitant
Pneumonia Other Serious Male 12/21/2007 Physician
Primary
Concomitant
Urinary Tract Infection Other Serious 8/1/2006 Female 187 lb 12/28/2007 Physician United States
Primary
Concomitant
Hypertension Hospitalization 10/24/2007 Female 154 lb 5/15/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Wheezing Hospitalization 11/13/2002 Male 7/21/2008 Other Health Professional United States
Primary
Concomitant
Osteonecrosis Disability 3/28/2008 83 Female 148 lb 11/26/2008 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 8/1/2006 Female 187 lb 1/20/2009 Physician United States
Primary
Concomitant
Renal Failure Other Serious 3/7/2008 Female 1/21/2009 Physician Germany
Primary
Concomitant
Interacting
Haemorrhagic Transformation Stroke Hospitalization 12/1/2007 Male 1/29/2009 Belgium
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 1/1/2008 78 Male 2/5/2009 Physician Germany
Primary
Secondary
Concomitant
Haemorrhagic Transformation Stroke Hospitalization 12/1/2007 Male 2/9/2009 Belgium
Primary
Concomitant
Skin Laceration Hospitalization 5/11/2008 Male 160 lb 2/12/2009 Consumer United States
Primary
Concomitant
Respiratory Failure Hospitalization 11/17/2008 Male 165 lb 2/18/2009 United States
Primary
Concomitant
Renal Failure Other Serious 3/7/2008 Female 121 lb 2/24/2009 Physician Germany
Primary
Concomitant
Interacting
Weight Increased Other Serious 1/1/2006 Male 2/20/2009 Physician Canada
Primary
Concomitant
Skin Ulcer 8/1/2008 Female 152 lb 3/14/2009 United States
Primary
Concomitant
Skin Exfoliation Other Serious 3/1/2009 Female 4/3/2009 Physician United States
Primary
Concomitant
Skin Exfoliation Other Serious 3/17/2009 Female 191 lb 4/21/2009 Physician United States
Primary
Concomitant
Paternal Drugs Affecting Foetus 24 Female 4/30/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 10/30/2008 Male 5/6/2009 Belgium
Primary
Concomitant
Hemiparesis Other Serious 11/1/2008 57 Female 5/28/2009 Physician New Zealand
Primary
Concomitant
Injection Site Pain Male 170 lb 6/12/2009 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 11/25/2007 Female 6/12/2009 Belgium
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/25/2007 Female 6/26/2009 Belgium
Primary
Secondary
Concomitant
Renal Failure Other Serious 3/7/2008 Female 121 lb 7/30/2009 Physician Germany
Primary
Concomitant
Interacting
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 8/10/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/13/2009 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/23/2009 Lawyer United States
Primary
Concomitant
Sjogren's Syndrome Hospitalization 1/1/2009 57 Female 187 lb 9/4/2009 Physician Netherlands
Primary
Concomitant
Urinary Tract Infection Other Serious 8/1/2006 Female 187 lb 9/22/2009 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 9/17/2009 United States
Primary
Concomitant
Pain Hospitalization 8/1/2009 Female 198 lb 12/3/2009 Brazil
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 Male 12/1/2009 Physician Canada
Primary
Concomitant
Rheumatoid Arthritis Other Serious 11/1/2007 Female 117 lb 12/4/2009 Brazil
Primary
Concomitant
Melaena Hospitalization 10/19/2009 Male 12/11/2009 Belgium
Primary
Concomitant
Thirst Other Serious 7/1/2009 66 Male 12/29/2009 Consumer Brazil
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 10/19/2009 Male 1/26/2010 Belgium
Primary
Concomitant
Nervousness 9/3/2009 Female 185 lb 1/29/2010 United States
Primary
Concomitant
Rash Generalised 9/2/2009 Female 170 lb 1/30/2010
Primary
Secondary
Concomitant
Paraesthesia Other Serious 12/1/2009 Male 150 lb 2/12/2010 United States
Primary
Concomitant
Loss Of Consciousness Other Serious 1/1/2005 Female 165 lb 2/12/2010 Brazil
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/11/2010 Female 2/10/2010 Physician United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 11/1/2009 Female 152 lb 2/23/2010 Physician Germany
Primary
Concomitant
Facial Paresis Hospitalization 9/2/2008 Male 159 lb 2/25/2010 Consumer United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/11/2010 Female 3/8/2010 Consumer United States
Primary
Concomitant
Rash Vesicular Other Serious 9/29/2009 Female 154 lb 3/31/2010 Physician Germany
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 1/5/2010 79 Male 170 lb 4/16/2010 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 11/1/2007 68 Female 117 lb 4/29/2010 Brazil
Primary
Concomitant
Pain Hospitalization 8/1/2009 53 Female 198 lb 5/4/2010 Brazil
Primary
Concomitant
Colitis Ischaemic Hospitalization 4/1/2010 81 Female 127 lb 5/7/2010 Physician United States
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 1/5/2010 79 Male 170 lb 6/7/2010 Physician United States
Primary
Concomitant
Sinus Tachycardia Hospitalization 5/12/2010 79 Female 6/10/2010 Physician United States
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 5/12/2010 79 Female 6/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 1/1/2010 66 Female 6/16/2010 Consumer Australia
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 4/1/2009 71 Female 143 lb 7/7/2010 Consumer United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2009 72 Female 154 lb 7/13/2010 Consumer Brazil
Primary
Concomitant
Liver Function Test Abnormal Other Serious 1/1/2010 66 Female 7/26/2010 Physician Australia
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2009 72 Female 154 lb 7/29/2010 Consumer Brazil
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 4/1/2009 71 Female 143 lb 8/18/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 4/18/2010 60 Female 234 lb 9/3/2010
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2009 72 Female 154 lb 9/4/2010 Consumer Brazil
Primary
Concomitant
Adenocarcinoma Life Threatening 57 Female 132 lb 9/9/2010 Other Health Professional Austria
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2009 52 Female 143 lb 9/10/2010 Consumer Brazil
Primary
Concomitant
Colon Cancer Life Threatening 1/1/2010 57 Female 132 lb 9/10/2010 Consumer Austria
Primary
Secondary
Concomitant
Blood Creatinine Increased 5/1/2010 84 Female 171 lb 9/16/2010 Physician United States
Primary
Concomitant
Gastritis Erosive Other Serious 8/1/2010 62 Male 170 lb 9/29/2010 Physician Germany
Primary
Concomitant
Tooth Disorder Hospitalization 8/19/2010 57 Male 115 lb 9/29/2010 Consumer Brazil
Primary
Concomitant
Rash Vesicular Other Serious 9/29/2009 48 Female 154 lb 10/22/2010 Physician Germany
Primary
Concomitant
Colitis Ischaemic Hospitalization 4/1/2010 81 Female 127 lb 10/28/2010 Physician United States
Primary
Concomitant
Tremor Hospitalization 2/13/2010 62 Female 121 lb 11/11/2010 Physician Belgium
Primary
Concomitant
Staphylococcal Infection Hospitalization 1/1/2010 68 Female 11/12/2010 Physician Finland
Primary
Secondary
Concomitant
Tremor Hospitalization 2/13/2010 62 Female 121 lb 11/15/2010 Physician Belgium
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/11/2010 69 Female 11/5/2010 Other Health Professional United States
Primary
Concomitant
Tremor Hospitalization 2/13/2010 62 Female 121 lb 11/17/2010 Physician Belgium
Primary
Concomitant
Colitis Ischaemic Hospitalization 4/1/2010 81 Female 127 lb 11/29/2010 Physician United States
Primary
Concomitant
Lymphoedema Hospitalization Female 12/7/2010 Physician Belgium
Primary
Concomitant
Lymphoedema Hospitalization Female 12/10/2010 Physician Belgium
Primary
Concomitant
Pseudomembranous Colitis Hospitalization 4/1/2010 81 Female 127 lb 12/13/2010 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 9/1/2009 61 Female 12/14/2010 Physician Belgium
Primary
Concomitant
Red Blood Cell Count Decreased Hospitalization 4/1/2010 81 Female 127 lb 12/17/2010 Physician United States
Primary
Concomitant
Wheezing Other Serious 11/1/2007 68 Female 117 lb 12/22/2010 Consumer Brazil
Primary
Concomitant
Pain In Extremity Other Serious 11/1/2007 68 Female 117 lb 1/4/2011 Consumer Brazil
Primary
Concomitant
Face Oedema Hospitalization 9/7/2010 69 Female 106 lb 1/6/2011 Consumer France
Primary
Concomitant
Angina Pectoris Other Serious 11/1/2007 68 Female 117 lb 1/17/2011 Physician Brazil
Primary
Concomitant
Angioedema Hospitalization 9/7/2010 69 Female 106 lb 1/28/2011 Consumer France
Primary
Secondary
Concomitant
Weight Decreased 1/1/2010 52 Male 400 lb 1/29/2011 Consumer United States
Primary
Secondary
Concomitant
Injection Site Pain Female 1/29/2011 Consumer United States
Primary
Concomitant
Injection Site Pain 9/1/2010 46 Female 188 lb 1/29/2011 Consumer United States
Primary
Concomitant
Injection Site Haemorrhage 11/15/2010 54 Female 1/30/2011 Consumer United States
Primary
Concomitant
Vomiting Female 190 lb 1/30/2011 Consumer United States
Primary
Concomitant
Oedema Hospitalization 9/1/2009 61 Female 2/4/2011 Physician Belgium
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 9/1/2009 61 Female 2/7/2011 Physician Belgium
Primary
Concomitant
Lymphoedema Hospitalization 9/1/2009 61 Female 2/8/2011 Physician Belgium
Primary
Concomitant
Arrhythmia Hospitalization 2/24/2010 60 Female 236 lb 2/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 12/11/2010 71 Female 148 lb 2/1/2011 Other Health Professional Germany
Primary
Concomitant
Renal Failure Chronic Hospitalization 12/1/2010 71 Female 148 lb 2/15/2011 Other Health Professional Germany
Primary
Concomitant
Lesion Excision Other Serious 1/25/2011 68 Female 3/1/2011 Consumer Australia
Primary
Concomitant
Malignant Melanoma Other Serious 1/25/2011 68 Female 3/9/2011 Consumer Australia
Primary
Concomitant
Altered State Of Consciousness Hospitalization 1/26/2011 72 Female 115 lb 3/14/2011 Consumer France
Primary
Concomitant
Pruritus Hospitalization 9/7/2010 69 Female 106 lb 3/16/2011 Consumer France
Primary
Concomitant
Syncope Other Serious 11/1/2010 77 Male 3/18/2011 Physician Germany
Primary
Concomitant
Altered State Of Consciousness Hospitalization 1/26/2011 72 Female 115 lb 3/18/2011 Consumer France
Primary
Concomitant
Diarrhoea Hospitalization 10/11/2010 70 Female 3/18/2011 Other Health Professional United States
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 2/18/2010 53 Female 182 lb 4/1/2011 Physician United States
Primary
Secondary
Concomitant
Emphysema Other Serious 10/1/2008 67 Female 164 lb 4/7/2011 Physician Germany
Primary
Secondary
Concomitant
Diarrhoea Other Serious 1/1/2010 69 4/15/2011 Physician Germany
Primary
Concomitant
Product Quality Issue Other Serious 3/1/2011 80 Female 5/3/2011 Other Health Professional Australia
Primary
Concomitant
Urinary Incontinence Other Serious 5/11/2010 63 Female 148 lb 5/9/2011 Physician Belgium
Primary
Concomitant
Neck Pain Other Serious 5/11/2010 63 Female 148 lb 5/10/2011 Physician Belgium
Primary
Concomitant
Product Quality Issue Other Serious 3/1/2011 80 Female 5/16/2011 Other Health Professional Australia
Primary
Concomitant
Cardiac Failure Other Serious 12/1/2010 71 Female 148 lb 5/26/2011 Physician Germany
Primary
Concomitant
Carcinoembryonic Antigen Increased Other Serious 4/13/2010 67 Female 117 lb 5/26/2011 Physician Canada
Primary
Secondary
Concomitant
Palatitis Hospitalization Female 5/31/2011 Physician Japan
Primary
Concomitant
Infusion Related Reaction Other Serious 6/1/2010 62 Female 170 lb 6/1/2011 Consumer United States
Primary
Concomitant
Influenza Like Illness Other Serious 5/21/2011 61 Female 6/7/2011 Pharmacist Germany
Primary
Concomitant
Ventricular Fibrillation Hospitalization 12/1/2010 71 Female 148 lb 6/10/2011 Physician Germany
Primary
Concomitant
Hypotonia Other Serious 5/21/2011 61 Female 6/16/2011 Pharmacist Germany
Primary
Concomitant
Infusion Related Reaction Other Serious 6/1/2010 62 Female 170 lb 6/24/2011 Consumer United States
Primary
Concomitant
Epiglottitis Life Threatening 2/19/2011 71 Female 110 lb 7/8/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Death Death Male 9/20/2011 Physician Germany
Primary
Concomitant
Mass Other Serious 4/1/2011 66 Female 10/14/2011 Physician United States
Primary
Concomitant
Drug Effect Decreased Other Serious 37 Female 10/17/2011 Physician Netherlands
Primary
Concomitant
Bronchitis 12/14/2010 60 Female 175 lb 10/28/2011 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 9/8/2011 68 Female 11/10/2011 Other Health Professional Spain
Primary
Concomitant
Headache 12/31/2010 44 Female 222 lb 11/17/2011 Pharmacist United States
Primary
Concomitant
Drug Interaction Hospitalization 4/1/2011 Male 216 lb 11/28/2011 Physician Germany
Primary
Concomitant
Interacting
Cerebrovascular Accident Other Serious Male 11/28/2011 Physician Germany
Primary
Concomitant
Fibromyalgia 37 Female 11/29/2011 Consumer United States
Primary
Secondary
Concomitant
Keratitis Other Serious 6/11/2011 Female 12/2/2011 Physician Germany
Primary
Concomitant
Weight Increased Hospitalization Female 12/5/2011 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 9/8/2011 68 Female 12/6/2011 Other Health Professional Spain
Primary
Concomitant
Hypoaesthesia Oral Other Serious 6/11/2011 Female 12/7/2011 Physician Germany
Primary
Concomitant
Drug Ineffective Hospitalization 1/1/2011 70 Female 235 lb 1/27/2012 Consumer United States
Primary
Concomitant
Rash 2/20/2011 63 Female 165 lb 1/27/2012 Other Health Professional United States
Primary
Concomitant
Oral Herpes 1/19/2011 74 Female 1/27/2012 Consumer United States
Primary
Concomitant
Sinusitis 2/1/2011 50 Male 250 lb 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Erythema 1/1/2011 61 Female 134 lb 1/28/2012 Consumer United States
Primary
Concomitant
Injury 5/1/2011 64 Female 1/28/2012 Consumer United States
Primary
Concomitant

Drug Data