Simvastatin combined with Thalidomide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sepsis Hospitalization 12/2/2003 Male 3/14/2006 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 12/2/2003 Male 3/28/2006 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 12/2/2003 Male 4/7/2006 Physician United States
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 62 Male 10/20/2006 Physician France
Primary
Secondary
Concomitant
Drug Eruption Other Serious 5/14/2006 82 Male 224 lb 5/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/22/2007 59 Male 146 lb 1/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/21/2007 Male 140 lb 2/16/2007 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 7/1/2007 67 Male 8/8/2007 Physician United Kingdom
Primary
Concomitant
Sinus Bradycardia Hospitalization 10/2/2007 68 Female 10/4/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sick Sinus Syndrome Life Threatening 10/2/2007 68 Female 10/11/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sarcoidosis Life Threatening 7/1/2007 67 Male 10/19/2007 Physician United Kingdom
Primary
Concomitant
Pain Other Serious 6/19/2007 68 Male 154 lb 11/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sinus Bradycardia Life Threatening 10/2/2007 68 Female 11/28/2007 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Hepatitis Fulminant Hospitalization 7/1/2007 85 Male 154 lb 12/22/2007 Physician
Primary
Concomitant
Upper Respiratory Tract Infection Death 2/3/2008 69 Male 2/4/2008 Other Health Professional United States
Primary
Concomitant
Upper Respiratory Tract Infection Death 2/3/2008 69 Male 2/21/2008 Other Health Professional United States
Primary
Concomitant
Chest Pain 2/27/2008 60 Male 3/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 66 Male 4/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 6/26/2006 59 Female 240 lb 4/15/2008 Physician United States
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 6/26/2006 59 Female 240 lb 4/25/2008 Physician United States
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 6/26/2006 59 Female 240 lb 5/13/2008 Physician United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 5/14/2008 63 Male 160 lb 5/19/2008 Other Health Professional United States
Primary
Concomitant
Ventricular Fibrillation Hospitalization 6/19/2008 58 Male 126 lb 6/23/2008 Physician Portugal
Primary
Secondary
Concomitant
Pneumonia Hospitalization 5/14/2008 63 Male 160 lb 5/19/2008 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 9/6/2008 Male 10/28/2008 Australia
Primary
Secondary
Concomitant
Pneumonia Hospitalization 9/30/2008 Male 163 lb 11/24/2008 Australia
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 71 Male 12/30/2008 Other Health Professional France
Primary
Concomitant
Pneumonitis Hospitalization Male 1/5/2009 Physician France
Primary
Concomitant
Pulmonary Toxicity Hospitalization 71 Male 1/9/2009 Other Health Professional France
Primary
Concomitant
Ventricular Fibrillation Death 6/19/2008 58 Male 3/25/2009 Portugal
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 6/19/2008 58 Male 126 lb 3/27/2009 Physician Portugal
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 6/19/2008 58 Male 126 lb 4/9/2009 Physician Portugal
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 6/19/2008 58 Male 126 lb 4/27/2009 Physician Portugal
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 Female 7/28/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 Female 10/1/2009 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 12/4/2004 Male 11/24/2009 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 12/4/2004 Male 12/14/2009 Physician United States
Primary
Concomitant
Sudden Cardiac Death Death Female 12/29/2009 Physician Thailand
Primary
Secondary
Concomitant
Pain Other Serious 6/19/2007 60 Male 12/22/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pain Other Serious 6/19/2007 60 Male 1/12/2010 Other Health Professional United Kingdom
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2004 Male 1/18/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 Female 1/20/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 Female 1/29/2010 Physician United States
Primary
Secondary
Concomitant
Sudden Cardiac Death Death 10/2/2009 Female 2/4/2010 Physician Germany
Primary
Secondary
Concomitant
Wound Drainage Other Serious 10/11/2004 Female 195 lb 2/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sudden Cardiac Death Death 10/2/2009 Female 2/11/2010 Physician Germany
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 2/23/2004 Male 224 lb 2/12/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 Female 2/13/2010 Physician United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 4/1/2003 Male 224 lb 3/1/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 Female 3/2/2010 Physician United States
Primary
Concomitant
Wound Drainage Other Serious 10/11/2004 Female 195 lb 3/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 5/1/2003 Male 3/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 4/1/2003 Male 224 lb 3/11/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 Female 3/12/2010 Physician United States
Primary
Concomitant
Sudden Cardiac Death Death 10/2/2009 Female 3/12/2010 Physician Germany
Primary
Secondary
Concomitant
Sudden Cardiac Death Death 10/2/2009 Female 3/15/2010 Physician Germany
Primary
Secondary
Concomitant
Walking Aid User Other Serious 5/1/2007 Male 219 lb 3/19/2010 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2004 Female 195 lb 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 4/1/2003 Male 3/19/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 Female 3/26/2010 Physician United States
Primary
Concomitant
X-ray Abnormal Other Serious 4/1/2003 Male 224 lb 3/26/2010 Other Health Professional United States
Primary
Concomitant
Walking Aid User Other Serious 5/1/2007 Male 219 lb 3/31/2010 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2004 Male 3/31/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 58 Female 4/8/2010 Physician United States
Primary
Concomitant
Wound Drainage Other Serious 1/1/2004 64 Female 195 lb 4/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/2006 54 Male 4/14/2010 United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 5/1/2007 68 Male 219 lb 4/15/2010 United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 4/1/2003 64 Male 224 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Wound Treatment Other Serious 1/1/2004 47 Male 4/16/2010 Physician United States
Primary
Concomitant
Vertebroplasty Other Serious 4/19/2001 81 Male 165 lb 4/19/2010 United States
Primary
Concomitant
Vertebroplasty Other Serious 4/19/2001 81 Male 165 lb 4/21/2010 United States
Primary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 10/29/2009 77 Female 122 lb 4/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 58 Female 4/27/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 58 Female 5/3/2010 Physician United States
Primary
Concomitant
Vascular Insufficiency Other Serious 1/1/1995 57 Male 5/11/2010 United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 4/1/2003 64 Male 224 lb 6/1/2010 United States
Primary
Concomitant
Wheezing Other Serious Male 6/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 4/1/2003 64 Male 224 lb 6/4/2010 United States
Primary
Concomitant
Wound Drainage Other Serious 1/1/2004 64 Female 195 lb 6/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/2004 47 Male 6/9/2010 Physician United States
Primary
Concomitant
X-ray Abnormal Other Serious 4/1/2003 64 Male 224 lb 6/10/2010 United States
Primary
Concomitant
Wheezing Other Serious Male 6/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vitamin B12 Deficiency Other Serious 1/16/2004 59 Male 6/11/2010 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 6/15/2010 United States
Primary
Secondary
Concomitant
Ulcer Other Serious 1/1/2002 81 Male 6/15/2010 United States
Primary
Concomitant
X-ray Abnormal Other Serious 4/1/2003 64 Male 224 lb 6/16/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2006 54 Male 6/21/2010 United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 4/1/2003 64 Male 224 lb 6/21/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 58 Female 6/24/2010 Physician United States
Primary
Concomitant
X-ray Abnormal Other Serious 4/1/2003 64 Male 224 lb 6/24/2010 United States
Primary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 10/29/2009 77 Female 122 lb 6/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vertebroplasty Other Serious 4/19/2001 81 Male 165 lb 7/7/2010 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 7/7/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious Male 7/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vitamin B12 Deficiency Other Serious 1/16/2004 59 Male 7/14/2010 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 7/19/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious Male 7/22/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/2006 54 Male 7/29/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious Male 7/28/2010 United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 4/27/2009 8/5/2010 Physician France
Primary
Concomitant
Vertebroplasty Other Serious 4/19/2001 81 Male 165 lb 8/5/2010 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 8/6/2010 United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 4/1/2003 64 Male 224 lb 8/17/2010 United States
Primary
Concomitant
Wheezing Other Serious Male 8/20/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/2006 54 Male 8/23/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/2006 54 Male 8/26/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious Male 8/27/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 58 Female 8/30/2010 Physician United States
Primary
Concomitant
Rales Hospitalization 7/28/2010 69 Male 9/2/2010 Physician France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 58 Female 9/9/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 9/17/2010 United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 6/30/2010 74 Female 9/23/2010 Physician France
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Life Threatening 6/30/2010 74 Female 9/24/2010 Consumer France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 58 Female 9/24/2010 Physician United States
Primary
Concomitant
Wheezing Other Serious Male 9/28/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 1/1/2002 59 Male 10/4/2010 United States
Primary
Secondary
Concomitant
Ulcer Other Serious 1/1/2002 81 Male 10/7/2010 United States
Primary
Concomitant
Ulcer Other Serious 1/1/2002 81 Male 10/7/2010 United States
Primary
Concomitant
Wound Infection Other Serious 5/1/2007 68 Male 219 lb 10/11/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 58 Female 10/15/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 58 Female 10/20/2010 Physician United States
Primary
Concomitant
Wheezing Other Serious 1/1/2002 59 Male 11/3/2010 United States
Primary
Secondary
Concomitant
Vertebroplasty Other Serious 4/19/2001 81 Male 165 lb 11/5/2010 United States
Primary
Concomitant
Pneumonia Hospitalization 10/21/2010 71 Female 165 lb 11/15/2010 Physician Germany
Primary
Secondary
Concomitant
Atrioventricular Block Other Serious 11/1/2010 74 Male 127 lb 11/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wheezing Other Serious 4/1/2003 79 Male 11/25/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 58 Female 12/1/2010 Physician United States
Primary
Concomitant
Vascular Graft Other Serious 5/1/1994 60 Male 12/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 4/1/2003 64 Male 224 lb 12/14/2010 United States
Primary
Concomitant
Vomiting Hospitalization 11/25/2010 72 Female 12/16/2010 Physician Germany
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/2004 47 Male 12/22/2010 Physician United States
Primary
Concomitant
Proctalgia Disability 8/28/2010 Male 12/23/2010 Physician Australia
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 58 Female 12/23/2010 Physician United States
Primary
Concomitant
Wheezing Other Serious 4/1/2003 79 Male 12/23/2010 United States
Primary
Secondary
Concomitant
Oedema Hospitalization 7/18/2010 86 Male 163 lb 12/29/2010 Pharmacist Germany
Primary
Concomitant
Lethargy Other Serious 5/1/1994 60 Male 1/10/2011 United States
Primary
Secondary
Concomitant
Atrioventricular Block Hospitalization 11/1/2010 74 Male 127 lb 1/19/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Proctalgia Disability 8/28/2010 70 Male 2/3/2011 Physician Australia
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2002 59 Male 2/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Hypoalbuminaemia Other Serious 5/1/1994 60 Male 2/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Proctalgia Disability 8/28/2010 70 Male 2/23/2011 Physician Australia
Primary
Concomitant
Pulmonary Oedema Hospitalization 1/1/2002 59 Male 3/4/2011 Lawyer United States
Primary
Secondary
Concomitant
Laceration Other Serious 1/1/1999 58 Female 3/18/2011 United States
Primary
Concomitant
Pneumonia Hospitalization 2/9/2011 74 Male 168 lb 3/21/2011 Physician France
Primary
Secondary
Concomitant
Hypomagnesaemia Other Serious 1/1/1995 57 Male 3/28/2011 Lawyer United States
Primary
Secondary
Concomitant
Bronchopneumonia Hospitalization 1/31/2011 76 Female 117 lb 3/30/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Congestive Cardiomyopathy Other Serious 4/1/2003 79 Male 4/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Back Pain Hospitalization 1/1/2002 59 Male 4/6/2011 United States
Primary
Secondary
Concomitant
Tooth Abscess Other Serious Male 4/6/2011 Other Health Professional United States
Primary
Concomitant
Bone Lesion Other Serious 12/16/2005 61 Male 136 lb 5/19/2011 Other Health Professional United States
Primary
Concomitant

Drug Data