Latanoprost combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Life Threatening 9/2/2003 Male 1/4/2006 Finland
Primary
Concomitant
Tachycardia Other Serious 1/1/2004 64 Male 203 lb 2/10/2006 Physician Switzerland
Primary
Secondary
Concomitant
Scleral Discolouration Other Serious 9/12/2005 Male 221 lb 3/31/2006 Pharmacist United States
Primary
Concomitant
Platelet Count Increased Hospitalization 7/10/2006 76 Male 181 lb 7/21/2006 Physician Australia
Primary
Secondary
Concomitant
Platelet Count Increased Other Serious 7/10/2006 76 Male 181 lb 7/21/2006 Australia
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 7/10/2006 76 Male 181 lb 8/15/2006 Switzerland
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 7/10/2006 76 Male 181 lb 8/18/2006 Physician Australia
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/10/2005 85 Female 8/25/2006 United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/10/2005 85 Female 8/28/2006 United Kingdom
Primary
Secondary
Concomitant
Helicobacter Infection Hospitalization 1/10/2005 85 Female 8/28/2006 United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 5/9/2006 68 Male 9/13/2006 United Kingdom
Primary
Concomitant
Haemorrhagic Stroke Hospitalization 7/4/2006 80 Female 10/11/2006 United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 9/1/2006 Female 11/7/2006 United States
Primary
Concomitant
Mental Disorder Other Serious 9/15/2006 80 Male 11/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Infection 7/10/2006 76 Male 181 lb 11/30/2006 Switzerland
Primary
Secondary
Concomitant
Palpitations Other Serious 9/28/2006 67 Female 154 lb 1/31/2007 Other Health Professional United Kingdom
Primary
Concomitant
Poor Quality Drug Administered 12/14/2006 62 Female 139 lb 2/12/2007 Pharmacist United States
Primary
Concomitant
External Ear Disorder Other Serious 6/1/2006 84 Male 176 lb 4/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
External Ear Disorder Other Serious 6/1/2006 84 Male 176 lb 4/2/2007 United Kingdom
Primary
Concomitant
Pulmonary Embolism Life Threatening 4/10/2007 55 Male 229 lb 4/17/2007 Pharmacist United States
Primary
Concomitant
Alopecia Other Serious 3/7/2007 9/18/2007 Consumer United Kingdom
Primary
Concomitant
Confusional State Hospitalization 9/1/2007 83 Female 10/3/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Retinal Detachment Hospitalization 10/1/2007 63 Female 10/24/2007 Pharmacist Netherlands
Primary
Secondary
Concomitant
Yellow Skin Hospitalization Male 11/19/2007 Physician Australia
Primary
Concomitant
Joint Stiffness 8/1/2007 59 Female 150 lb 12/14/2007 Consumer United States
Primary
Secondary
Concomitant
Syncope Vasovagal Other Serious 64 Male 12/7/2007 Canada
Primary
Secondary
Concomitant
Erythema Hospitalization 1/1/2007 87 Female 126 lb 1/2/2008 Other Health Professional Finland
Primary
Concomitant
Serotonin Syndrome Other Serious 7/23/2007 Female 183 lb 1/24/2008 Consumer United States
Primary
Concomitant
Retinal Detachment Hospitalization 10/1/2007 Female 2/5/2008 Pharmacist Netherlands
Primary
Secondary
Concomitant
Procedural Complication Life Threatening 10/1/2007 64 Male 2/22/2008 Physician Canada
Primary
Secondary
Concomitant
Wheezing Disability 9/1/2007 68 Male 3/6/2008 Other Health Professional United Kingdom
Primary
Concomitant
Wound Infection Hospitalization 10/8/2007 Female 179 lb 5/30/2008 United Kingdom
Primary
Concomitant
Total Lung Capacity Decreased Other Serious 2/21/2008 Male 161 lb 6/30/2008 Physician Israel
Primary
Secondary
Concomitant
Syncope Other Serious 7/11/2007 65 Female 175 lb 6/9/2008 Consumer United States
Primary
Concomitant
Joint Swelling Other Serious 5/23/2008 69 Female 176 lb 7/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Total Lung Capacity Decreased Other Serious 2/21/2008 Male 161 lb 7/24/2008 Physician Israel
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 7/8/2006 91 Female 7/22/2008 Physician United States
Primary
Concomitant
Pneumonia Aspiration Hospitalization 7/8/2006 91 Female 8/19/2008 Physician United States
Primary
Concomitant
Malaise 5/16/2008 Male 180 lb 8/27/2008 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 8/4/2008 80 Female 110 lb 10/6/2008 Pharmacist United States
Primary
Concomitant
Syncope Other Serious 7/11/2007 65 Female 175 lb 9/12/2008 United States
Primary
Concomitant
Total Lung Capacity Decreased Other Serious 2/21/2008 Male 161 lb 11/5/2008 Physician Israel
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 82 Female 12/9/2008 Other Health Professional Japan
Primary
Concomitant
Injection Site Irritation 7/1/2008 Male 12/12/2008 Physician United States
Primary
Concomitant
Troponin Increased Other Serious 1/1/2003 78 Male 140 lb 1/8/2009 United States
Primary
Concomitant
Postoperative Wound Infection Hospitalization 10/8/2007 Female 179 lb 2/3/2009 United Kingdom
Primary
Concomitant
Postoperative Wound Infection Hospitalization 10/8/2007 Female 179 lb 2/5/2009 United Kingdom
Primary
Concomitant
Bone Pain Other Serious 1/8/2009 Male 185 lb 3/20/2009 Germany
Primary
Secondary
Concomitant
Rash Pustular Other Serious 2/18/2009 Female 209 lb 3/18/2009 United Kingdom
Primary
Concomitant
Bone Pain Other Serious 1/8/2009 Male 187 lb 4/1/2009 Germany
Primary
Secondary
Concomitant
Bone Pain Other Serious 1/8/2009 Male 187 lb 4/3/2009 Germany
Primary
Secondary
Concomitant
Troponin Increased Other Serious 1/1/2003 78 Male 140 lb 4/14/2009 United States
Primary
Concomitant
Surgery Other Serious 1/8/2009 Male 185 lb 4/14/2009 Germany
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 3/20/2009 Male 181 lb 4/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Drug Ineffective Other Serious 3/20/2009 Male 181 lb 4/22/2009 Consumer United Kingdom
Primary
Concomitant
Blood Pressure Increased Other Serious 3/20/2009 Male 4/22/2009 Other Health Professional United Kingdom
Primary
Concomitant
Prosthesis Implantation Other Serious 1/8/2009 Male 161 lb 5/28/2009 Germany
Primary
Secondary
Concomitant
Bone Pain Other Serious 1/8/2009 Male 161 lb 6/10/2009 Germany
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 6/1/2008 77 Male 190 lb 7/22/2009 Consumer Germany
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 6/1/2008 77 Male 190 lb 7/22/2009 Consumer Germany
Primary
Secondary
Concomitant
Lip Neoplasm Malignant Stage Unspecified Other Serious 12/7/2007 Female 137 lb 7/31/2009 Other Health Professional United Kingdom
Primary
Concomitant
Basal Cell Carcinoma Other Serious 7/12/2007 Female 137 lb 8/31/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 12/22/2008 84 Female 128 lb 9/8/2009 Consumer United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 8/23/2009 72 Female 137 lb 9/5/2009 Pharmacist United States
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 12/7/2007 Female 137 lb 9/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Ill-defined Disorder 1/24/2009 69 Male 9/16/2009 Consumer United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 12/7/2007 Female 137 lb 10/1/2009 Other Health Professional United Kingdom
Primary
Concomitant
Drug Ineffective Other Serious 3/20/2009 Male 9/30/2009 United Kingdom
Primary
Concomitant
External Ear Disorder Other Serious 6/1/2006 84 Male 11/10/2009 United Kingdom
Primary
Concomitant
Serotonin Syndrome Other Serious 7/23/2007 Female 183 lb 11/30/2009 Consumer United States
Primary
Concomitant
Acute Generalised Exanthematous Pustulosis Other Serious 2/18/2009 82 Female 209 lb 12/28/2009 United Kingdom
Primary
Concomitant
Wound Infection Hospitalization 73 Male 1/22/2010 United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 1/29/2010 Israel
Primary
Concomitant
Vomiting Hospitalization 12/14/2009 86 Female 115 lb 2/9/2010 Pharmacist United States
Primary
Secondary
Concomitant
Stress Urinary Incontinence Other Serious Female 3/2/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Urinary Retention Other Serious 12/23/2009 Female 3/5/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Myocardial Ischaemia Hospitalization 48 Male 190 lb 3/30/2010 Pharmacist United States
Primary
Concomitant
Urinary Retention Other Serious 12/23/2009 59 Female 4/27/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 70 Female 6/18/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 6/22/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 70 Female 6/23/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 6/29/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Cardiac Failure Congestive Life Threatening 4/10/2007 55 Male 229 lb 6/28/2010 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 6/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 7/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization Female 7/7/2010 Other Health Professional Israel
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 7/9/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/12/2010 Physician Israel
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 7/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Required Intervention 70 Female 7/2/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 7/13/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization Female 7/13/2010 Other Health Professional Israel
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 7/6/2010 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 7/8/2010 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 7/18/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/20/2010 Physician Israel
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 70 Female 7/13/2010 Israel
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 7/14/2010 Other Health Professional Denmark
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 7/21/2010 Other Health Professional Israel
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 7/21/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Device Issue Male 160 lb 9/20/2010 Consumer United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Hospitalization 4/17/2009 Female 9/24/2010 Consumer Switzerland
Primary
Concomitant
Sleep Disorder Other Serious 1/1/2010 62 Male 9/28/2010 Consumer United States
Primary
Secondary
Concomitant
Headache Other Serious 6/21/2010 Male 2/1/2011 Physician Switzerland
Primary
Concomitant
Myocardial Infarction Hospitalization 48 Male 190 lb 2/10/2011 Pharmacist United States
Primary
Concomitant
Alcohol Abuse Other Serious 7/1/2004 43 Male 282 lb 3/22/2011 Lawyer United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 1/13/2011 58 Male 204 lb 4/13/2011 Physician United Kingdom
Primary
Concomitant
Haemoglobin Decreased Life Threatening 1/13/2011 58 Male 204 lb 4/21/2011 Other Health Professional United Kingdom
Primary
Concomitant
Flushing 78 Female 147 lb 6/30/2011 Physician United States
Primary
Concomitant
Abdominal Pain Upper Hospitalization 4/1/2011 73 Female 7/5/2011 Consumer United States
Primary
Concomitant
Myopathy Hospitalization 6/4/2011 83 Male 7/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 6/4/2011 83 Male 7/5/2011 Other Health Professional
Primary
Secondary
Concomitant
Colitis Hospitalization 6/2/2011 85 Female 147 lb 8/2/2011 Physician United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 8/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haematuria Disability 7/10/2011 83 Male 192 lb 8/4/2011 Physician Australia
Primary
Secondary
Concomitant
Colon Adenoma Disability 6/2/2011 85 Female 147 lb 8/15/2011 Physician United States
Primary
Concomitant
Osteoarthritis Other Serious Male 8/30/2011 Other Health Professional United States
Primary
Concomitant
Asthenia 6/1/2011 Female 9/6/2011 Physician United States
Primary
Concomitant
Hypotension Hospitalization 6/26/2011 71 Male 185 lb 8/15/2011 Pharmacist United States
Primary
Concomitant
Aortic Valve Sclerosis Other Serious Male 9/7/2011 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Disability 6/2/2011 85 Female 147 lb 9/12/2011 Physician United States
Primary
Concomitant
Colitis Disability 6/2/2011 85 Female 147 lb 9/26/2011 Physician United States
Primary
Concomitant
Dyspnoea Other Serious 71 Female 9/28/2011 United States
Primary
Secondary
Diarrhoea Other Serious 71 Female 10/18/2011 Consumer United States
Primary
Interacting
Visual Impairment Other Serious 71 Female 10/19/2011 Consumer United States
Primary
Interacting
Nasal Disorder Other Serious 71 Female 10/20/2011 Consumer United States
Primary
Interacting
Diarrhoea Other Serious 71 Female 10/20/2011 Other Health Professional United States
Primary
Secondary
Intraocular Pressure Increased Other Serious 9/13/2011 71 Female 10/27/2011 Consumer United States
Primary
Secondary
Concomitant
Aortic Valve Incompetence Other Serious Male 10/28/2011 Lawyer United States
Primary
Concomitant
Eye Oedema Other Serious 71 Female 10/21/2011 Consumer United States
Primary
Secondary
Mental Impairment Other Serious 71 Female 11/2/2011 Consumer United States
Primary
Secondary
Colon Cancer Hospitalization 7/25/2011 82 Male 161 lb 11/8/2011 Physician New Zealand
Primary
Concomitant
Hair Growth Abnormal 9/1/2011 79 Male 170 lb 11/17/2011 Physician United States
Primary
Secondary
Concomitant
Intraocular Pressure Increased Other Serious 9/13/2011 71 Female 11/20/2011 Consumer United States
Primary
Secondary
Concomitant
Blood Electrolytes Abnormal Other Serious 71 Female 11/17/2011 Consumer United States
Primary
Secondary
Concomitant
Intraocular Pressure Increased Other Serious 11/1/2011 70 Male 12/2/2011 Pharmacist United States
Primary
Concomitant
Hypophagia Hospitalization 82 Female 121 lb 12/27/2011 Other Health Professional United Kingdom
Primary
Concomitant
Blood Chloride Increased Hospitalization 12/1/2011 74 Female 972 lb 12/28/2011 United States
Primary
Secondary
Concomitant
Confusional State Hospitalization 82 Female 121 lb 12/22/2011 Other Health Professional
Primary
Concomitant
Confusional State Hospitalization 82 Female 121 lb 12/30/2011 Other Health Professional United Kingdom
Primary
Concomitant
Hyponatraemia Hospitalization 82 Female 121 lb 1/3/2012 Other Health Professional United Kingdom
Primary
Concomitant
Hyponatraemia Hospitalization 82 Female 12/27/2011 Other Health Professional Denmark
Primary
Concomitant
Hypophagia Hospitalization 82 Female 12/29/2011 United Kingdom
Primary
Concomitant
Intraocular Pressure Increased Other Serious 1/1/2011 69 Male 1/18/2012 Pharmacist United States
Primary
Concomitant
Blood Sodium Increased Other Serious 1/1/2011 83 Male 1/26/2012 Other Health Professional United Kingdom
Primary
Concomitant
Crohn's Disease 45 Male 1/29/2012 Consumer United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization Male 2/6/2012 Lawyer United States
Primary
Concomitant
Intraocular Pressure Increased Other Serious 1/1/2011 69 Male 2/20/2012 Physician United States
Primary
Concomitant
Haemorrhage Intracranial Death 70 Female 3/22/2012 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 3/22/2012 59 Male 4/2/2012 Other Health Professional United States
Primary
Concomitant

Drug Data