Rosiglitazone combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cardiac Failure Congestive Required Intervention 1/25/2006 60 Male 281 lb 1/25/2006 Pharmacist United States
Primary
Concomitant
Arrhythmia Required Intervention 10/31/2005 58 Male 269 lb 10/31/2005 Pharmacist United States
Primary
Concomitant
Oedema Hospitalization 11/8/2005 62 292 lb 11/8/2005 Pharmacist United States
Primary
Concomitant
Scar Other Serious 1/1/2003 69 Female 150 lb 2/9/2006 Consumer United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 10/24/2005 58 Male 203 lb 12/1/2005 Pharmacist United States
Primary
Concomitant
Hypoglycaemia Other Serious 89 Male 2/21/2006 Physician United States
Primary
Concomitant
Flatulence 12/1/2005 65 Male 2/27/2006 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 1/20/2006 48 Female 77 lb 3/14/2006 Consumer United Kingdom
Primary
Concomitant
Cerebrovascular Accident Hospitalization 8/10/2005 71 Male 250 lb 12/27/2005 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 70 Male 3/13/2006 Physician United States
Primary
Secondary
Concomitant
Amenorrhoea Other Serious 37 Female 139 lb 3/22/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Blood Glucose Increased 9/29/2005 63 Male 198 lb 1/20/2006 Consumer United States
Primary
Concomitant
Pancreatitis Hospitalization 3/22/2006 88 Male 193 lb 4/6/2006 Pharmacist United States
Primary
Concomitant
Chest Pain Hospitalization 3/30/2006 5/3/2006 Physician United States
Primary
Concomitant
Syncope Life Threatening 4/2/2006 Female 331 lb 5/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Fluid Overload Hospitalization 11/19/2005 Male 5/16/2006 Pharmacist United States
Primary
Concomitant
Loss Of Consciousness Life Threatening 4/6/2006 61 Male 213 lb 5/19/2006 Other Health Professional Puerto Rico
Primary
Secondary
Concomitant
Confusional State Hospitalization 2/2/2006 64 Male 174 lb 4/18/2006 Pharmacist United States
Primary
Concomitant
Lethargy Other Serious 4/24/2006 72 Male 6/1/2006 Consumer United Kingdom
Primary
Concomitant
Hypoglycaemic Coma Life Threatening 4/6/2006 61 Male 213 lb 6/2/2006 Other Health Professional Puerto Rico
Primary
Secondary
Concomitant
Urticaria Hospitalization 2/8/2006 44 Male 247 lb 2/8/2006 Other Health Professional United States
Primary
Concomitant
Oral Intake Reduced Hospitalization 5/23/2006 60 Male 148 lb 5/25/2006 Pharmacist United States
Primary
Secondary
Concomitant
Rash Pruritic 4/10/2006 67 Male 238 lb 8/1/2006 Pharmacist United States
Primary
Concomitant
Urinary Hesitation Hospitalization 7/29/2006 72 Male 219 lb 8/2/2006 Pharmacist United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 2/17/2006 57 Female 231 lb 8/17/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/19/2006 77 Male 8/23/2006 Other Health Professional France
Primary
Concomitant
Retching Hospitalization 5/14/2006 74 Male 243 lb 6/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Ulcer Life Threatening 4/2/2006 Female 331 lb 8/24/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Lactic Acidosis Hospitalization 77 Male 8/22/2006 United Kingdom
Primary
Concomitant
Lactic Acidosis Hospitalization 77 Male 8/23/2006 United Kingdom
Primary
Concomitant
Syncope Life Threatening 4/2/2006 Female 331 lb 9/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 8/24/2006 69 Male 241 lb 8/30/2006 Pharmacist United States
Primary
Concomitant
Nervousness Other Serious 5/20/2006 71 Female 215 lb 9/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Lethargy Other Serious 8/3/2006 72 Male 172 lb 9/28/2006 Consumer United Kingdom
Primary
Concomitant
Neutropenia Other Serious 74 Female 175 lb 10/10/2006 Physician
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/26/2006 69 Male 221 lb 10/5/2006 Pharmacist United States
Primary
Concomitant
Neutropenia Other Serious 74 Female 175 lb 10/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 7/18/2006 58 Male 419 lb 7/24/2006 Pharmacist United States
Primary
Concomitant
Loss Of Consciousness Other Serious 8/27/2006 66 Male 219 lb 9/29/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/23/2006 59 Male 10/26/2006 United States
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 8/14/2006 67 Male 11/1/2006 Physician United Kingdom
Primary
Concomitant
Psychotic Disorder Required Intervention 35 Male 11/7/2006 United States
Primary
Concomitant
Psychotic Disorder Other Serious 8/14/2006 67 Male 11/13/2006 United Kingdom
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 8/14/2006 67 Male 11/8/2006 United Kingdom
Primary
Secondary
Concomitant
Oedema Required Intervention 11/29/2006 61 Male 222 lb 11/29/2006 Pharmacist United States
Primary
Concomitant
Occult Blood Positive Hospitalization 12/4/2006 72 Male 291 lb 1/10/2007 Pharmacist United States
Primary
Secondary
Concomitant
Waist Circumference Increased Hospitalization 1/22/2007 82 Male 196 lb 2/6/2007 Physician United States
Primary
Secondary
Concomitant
Occult Blood Positive Hospitalization 11/22/2006 Male 180 lb 12/22/2006 Pharmacist United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 1/22/2007 82 Male 196 lb 2/13/2007 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 10/20/2006 59 Male 313 lb 10/23/2006 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Other Serious 10/30/2006 72 Male 217 lb 12/13/2006 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 3/15/2007 74 Male 272 lb 3/27/2007 Pharmacist United States
Primary
Concomitant
Osteomyelitis Hospitalization 9/27/2006 58 Male 11/15/2006 Physician United States
Primary
Concomitant
Orthopnoea Other Serious 5/1/2006 70 Male 179 lb 4/10/2007 Consumer United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2006 74 Male 217 lb 4/11/2007 Consumer United States
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious 1/25/2007 58 Male 247 lb 4/12/2007 United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Other Serious 3/9/2007 58 Male 219 lb 3/21/2007 Pharmacist United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 3/17/2007 58 Male 219 lb 3/21/2007 Pharmacist United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 11/21/2006 73 Male 180 lb 11/21/2006 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2006 74 Male 216 lb 4/30/2007 Consumer United States
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 12/5/2006 Female 269 lb 5/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Bone Marrow Failure Hospitalization 3/29/2007 60 Male 5/8/2007 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 6/1/2006 71 Male 229 lb 5/21/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Disability 1/1/2005 84 Male 225 lb 12/13/2006 Consumer United States
Primary
Concomitant
Pulmonary Oedema Other Serious 9/1/2006 71 Male 5/18/2007 United Kingdom
Primary
Secondary
Pulmonary Oedema Life Threatening 6/1/2006 71 Male 229 lb 5/22/2007 United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 6/1/2006 71 Male 229 lb 5/24/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 61 Female 5/31/2007 Other Health Professional Germany
Primary
Concomitant
Renal Failure Hospitalization 70 Male 6/14/2007
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 6/8/2007 65 Male 205 lb 6/18/2007 Physician Sweden
Primary
Concomitant
Vomiting Other Serious 6/1/2006 71 Male 229 lb 6/18/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2006 74 Male 216 lb 6/12/2007 Consumer United States
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 12/5/2005 Female 269 lb 6/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Alkalosis Hospitalization 2/20/2007 Male 193 lb 6/15/2007 Pharmacist United States
Primary
Concomitant
Pulmonary Oedema Life Threatening 6/1/2006 71 Male 229 lb 6/15/2007 United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 9/1/2006 71 Male 6/14/2007 United Kingdom
Primary
Secondary
Mania Other Serious 6/1/2007 73 Male 6/29/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pleural Effusion Other Serious 6/1/2006 7/11/2007 Consumer United Kingdom
Primary
Concomitant
Pulmonary Oedema Life Threatening 6/1/2006 71 Male 229 lb 7/6/2007 United Kingdom
Primary
Secondary
Concomitant
Rib Fracture Hospitalization 1/1/2005 64 Male 200 lb 7/13/2007 Consumer United States
Primary
Concomitant
Psychotic Disorder Other Serious 8/14/2006 67 Male 7/17/2007
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 8/14/2006 67 Male 7/13/2007 United Kingdom
Primary
Concomitant
Pneumonia Death 49 Female 235 lb 7/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 8/14/2006 67 Male 7/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 8/1/2006 67 Male 7/23/2007 Physician United Kingdom
Primary
Concomitant
Pneumonia Death 49 Female 7/24/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Death 12/25/2006 49 Female 235 lb 7/26/2007
Primary
Secondary
Concomitant
Pneumonia Death 49 Female 7/26/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Musculoskeletal Chest Pain Hospitalization 11/15/2006 Female 269 lb 7/27/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Musculoskeletal Chest Pain Hospitalization 12/5/2006 Female 269 lb 7/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Psychotic Disorder Other Serious 8/14/2006 67 Male 7/21/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 8/14/2006 67 Male 7/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
Angina Pectoris Disability 2/1/2007 62 Male 231 lb 8/10/2007 Consumer United Kingdom
Primary
Concomitant
Tremor Hospitalization 8/1/2006 55 Female 8/18/2007 Pharmacist United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 7/14/2007 65 Female 194 lb 8/30/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Hallucination, Visual Other Serious 12/12/2006 51 Male 279 lb 9/6/2007 Consumer United States
Primary
Concomitant
Vision Blurred Disability 6/1/2007 76 Female 154 lb 9/10/2007 Consumer United Kingdom
Primary
Concomitant
Oedema Peripheral Other Serious 5/1/2007 81 Male 239 lb 9/12/2007 Consumer United Kingdom
Primary
Concomitant
Lower Limb Fracture Hospitalization 6/2/2007 64 Male 200 lb 9/20/2007 Consumer United States
Primary
Concomitant
Hypertension Other Serious 8/13/2007 59 Male 205 lb 9/25/2007 Consumer United Kingdom
Primary
Concomitant
Drug Withdrawal Syndrome Other Serious 8/14/2006 67 Male 10/9/2007 United Kingdom
Primary
Concomitant
Psychotic Disorder Other Serious 8/14/2006 67 Male 10/9/2007 United Kingdom
Primary
Concomitant
Vitamin B12 Deficiency Other Serious 3/1/2006 Male 10/23/2007 Other Health Professional Germany
Primary
Concomitant
Interacting
Tachycardia Hospitalization 7/15/2007 63 Male 234 lb 10/26/2007 Physician Sweden
Primary
Concomitant
Vitamin B12 Deficiency Disability 3/1/2006 Male 10/24/2007 United Kingdom
Primary
Concomitant
Vitamin B12 Deficiency Disability 3/1/2006 Male 10/24/2007 United Kingdom
Primary
Secondary
Concomitant
Vitamin B12 Deficiency Other Serious 3/1/2006 Male 216 lb 10/29/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Vitamin B12 Deficiency Other Serious 3/1/2006 Male 216 lb 10/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Angioedema Life Threatening 8/3/2007 60 Female 11/5/2007 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 3/15/2005 Male 183 lb 11/7/2007 Physician Canada
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 9/17/2007 55 Female 11/9/2007 Consumer United Kingdom
Primary
Concomitant
Chest Pain Other Serious 7/1/2007 44 Male 182 lb 11/19/2007 Consumer United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 53 Female 11/21/2007 Pharmacist United Kingdom
Primary
Concomitant
Epilepsy Other Serious 39 Male 11/21/2007 Other Health Professional Germany
Primary
Concomitant
Angioedema Life Threatening 8/3/2007 60 Female 11/26/2007 Physician United Kingdom
Primary
Concomitant
Epilepsy Other Serious 39 Male 11/19/2007 United Kingdom
Primary
Concomitant
Epilepsy Other Serious 11/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Suicidal Ideation Other Serious 45 Female 255 lb 11/29/2007 Consumer United Kingdom
Primary
Concomitant
Epilepsy Other Serious 39 Male 229 lb 11/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Epilepsy Other Serious 39 Male 11/26/2007 United Kingdom
Primary
Concomitant
Pancreatitis Acute Hospitalization 8/28/2005 62 Male 278 lb 12/3/2007 Physician United States
Primary
Secondary
Concomitant
Acute Myocardial Infarction Life Threatening 11/2/2007 68 Male 176 lb 1/8/2008 Consumer United Kingdom
Primary
Concomitant
Renal Failure Life Threatening 1/1/2006 68 Male 198 lb 1/11/2008 Consumer United Kingdom
Primary
Concomitant
Renal Failure Life Threatening 1/1/2006 68 Male 198 lb 1/24/2008 Consumer United Kingdom
Primary
Concomitant
Peripheral Vascular Disorder Disability 8/1/2007 81 Female 119 lb 1/29/2008 Consumer United Kingdom
Primary
Concomitant
Pancreatitis Acute Hospitalization 1/1/2005 62 Male 126 lb 2/11/2008 Physician United States
Primary
Concomitant
Wound Necrosis Life Threatening 4/2/2006 Female 331 lb 2/21/2008 United Kingdom
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 2/21/2008 46 Female 255 lb 3/3/2008 Consumer United Kingdom
Primary
Concomitant
Pain In Jaw Life Threatening 12/5/2007 75 Male 3/3/2008 Pharmacist Saudi Arabia
Primary
Concomitant
Visual Disturbance Disability 10/1/2007 57 Female 315 lb 3/3/2008 Consumer United Kingdom
Primary
Concomitant
Pancreatitis Acute Hospitalization 8/28/2005 62 Male 126 lb 2/28/2008 Physician United States
Primary
Concomitant
Glomerulonephritis Hospitalization 2/15/2008 40 Female 210 lb 3/20/2008 Consumer United Kingdom
Primary
Concomitant
Milk-alkali Syndrome Other Serious 70 Male 3/20/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Constipation Hospitalization 3/23/2008 70 Male 4/2/2008 Physician Sweden
Primary
Concomitant
Skin Necrosis Life Threatening 4/2/2006 Female 331 lb 3/28/2008 Consumer
Primary
Secondary
Concomitant
Constipation Hospitalization 3/23/2008 70 Male 4/10/2008 Physician Sweden
Primary
Concomitant
Constipation Hospitalization 3/23/2008 70 Male 4/18/2008 Physician Sweden
Primary
Concomitant
Psychotic Disorder Other Serious 8/14/2006 67 Male 8/9/2007 United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 3/23/2008 70 Male 5/20/2008 Physician Sweden
Primary
Concomitant
Constipation Hospitalization 3/23/2008 70 Male 5/23/2008 Physician Sweden
Primary
Concomitant
Depression Hospitalization 1/1/2007 44 Male 280 lb 5/20/2008 United Kingdom
Primary
Concomitant
Peripheral Vascular Disorder Disability 8/1/2007 81 Female 119 lb 5/29/2008 Consumer United Kingdom
Primary
Concomitant
Depression Hospitalization 1/1/2007 44 Male 280 lb 6/9/2008
Primary
Concomitant
Syncope Life Threatening 4/2/2006 Female 7/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Constipation Hospitalization 3/1/2008 70 Male 7/21/2008 Physician Sweden
Primary
Concomitant
Chest Pain 76 Male 7/24/2008 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 9/13/2007 Male 8/18/2008 Physician
Primary
Concomitant
Skin Burning Sensation 6/25/2008 Male 8/29/2008 United States
Primary
Concomitant
Dyspepsia Hospitalization 3/8/2008 48 Male 215 lb 9/4/2008 Physician Brazil
Primary
Concomitant
Night Sweats Other Serious 7/1/2008 Male 9/8/2008 Other Health Professional United Kingdom
Primary
Concomitant

Drug Data