Glyceryl Trinitrate combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Skin Ulcer Hospitalization 2/13/2002 Female 1/4/2006 France
Primary
Concomitant
Renal Failure Life Threatening 9/2/2003 Male 1/4/2006 Finland
Primary
Concomitant
Coronary Ostial Stenosis Hospitalization 11/21/2005 71 Male 192 lb 1/4/2006 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/13/2005 56 Male 176 lb 1/4/2006 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/13/2005 56 Male 176 lb 1/12/2006 Netherlands
Primary
Secondary
Concomitant
Stent Occlusion Hospitalization 7/25/2005 64 Male 183 lb 1/12/2006 Poland
Primary
Secondary
Concomitant
Retroperitoneal Haematoma Life Threatening 2/16/2004 66 Male 1/19/2006 Consumer Poland
Primary
Concomitant
Somnolence Hospitalization 6/28/2005 62 Male 141 lb 1/24/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Rash Vesicular Other Serious 43 Male 2/2/2006 United Kingdom
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Subcutaneous Haematoma Hospitalization 6/15/2005 66 Male 198 lb 2/9/2006 Poland
Primary
Concomitant
Interacting
Coma Death 3/15/2004 77 Male 2/15/2006 United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/23/2006 United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 12/13/2005 56 Male 181 lb 2/24/2006 Netherlands
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/13/2005 56 Male 181 lb 3/8/2006 Netherlands
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Hospitalization 11/6/2005 53 Male 12/27/2005 Consumer United States
Primary
Concomitant
Vitreous Haemorrhage Hospitalization 7/18/2002 49 Male 12/29/2005 United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 7/1/2004 80 Male 190 lb 12/21/2005 Physician United States
Primary
Concomitant
Hypoglycaemia Hospitalization 3/17/2006 46 Female 4/13/2006 Other Health Professional Netherlands
Primary
Concomitant
Hypoglycaemia Hospitalization 3/17/2006 46 Female 4/17/2006 Other Health Professional Netherlands
Primary
Concomitant
Thrombocytopenia Other Serious 4/2/2004 66 Female 5/5/2006 Poland
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 2/21/2005 68 Male 154 lb 5/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Total Lung Capacity Decreased Other Serious 9/1/2005 79 Female 6/29/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urticaria Other Serious 8/26/2005 76 Male 176 lb 7/17/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Syncope Hospitalization 11/7/2005 77 Male 7/14/2006 United Kingdom
Primary
Concomitant
Granulocytopenia Required Intervention 4/19/2006 62 Male 180 lb 6/21/2006 United States
Primary
Concomitant
Hypertension Other Serious 1/1/2000 73 Male 217 lb 7/19/2006 Consumer United Kingdom
Primary
Concomitant
Unevaluable Event Hospitalization Male 148 lb 8/21/2006 Physician Germany
Primary
Concomitant
Retroperitoneal Haemorrhage Other Serious 9/17/2004 74 Female 141 lb 8/28/2006 Australia
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization Male 148 lb 8/30/2006 Physician Germany
Primary
Concomitant
Myalgia Other Serious 5/9/2006 79 Male 182 lb 9/19/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Panic Attack Hospitalization 9/3/2006 63 Male 258 lb 10/5/2006 Germany
Primary
Concomitant
High Density Lipoprotein Decreased Other Serious 72 Male 174 lb 10/16/2006 Other Health Professional France
Primary
Secondary
Concomitant
Myositis Life Threatening 7/30/2006 79 Female 110 lb 10/25/2006 United Kingdom
Primary
Concomitant
Pneumonia Other Serious 10/8/2006 Male 123 lb 11/2/2006 Physician Spain
Primary
Concomitant
Myocardial Infarction Other Serious 7/1/2006 69 Female 10/31/2006 Physician United Kingdom
Primary
Concomitant
Tremor Hospitalization 9/15/2006 61 Male 11/20/2006 Consumer United Kingdom
Primary
Concomitant
Urticaria Other Serious 8/26/2005 76 Male 176 lb 11/15/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization Male 12/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Skin Oedema Hospitalization 76 Male 12/14/2006 Other Health Professional United States
Primary
Concomitant
Shock Hospitalization Male 148 lb 12/30/2006 Physician Germany
Primary
Concomitant
High Density Lipoprotein Decreased Other Serious 1/1/2005 72 Male 174 lb 1/5/2007 Other Health Professional France
Primary
Secondary
Concomitant
Malaise Hospitalization 12/1/2006 60 Male 194 lb 3/12/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Rash Generalised Hospitalization 11/24/2006 89 Male 4/6/2007 United Kingdom
Primary
Secondary
Concomitant
Swelling Hospitalization 11/24/2006 89 Male 187 lb 4/3/2007 United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 11/24/2006 89 Male 3/29/2007 United Kingdom
Primary
Concomitant
Syncope Hospitalization 12/1/2006 60 Male 4/11/2007 Other Health Professional France
Primary
Secondary
Concomitant
Pain Disability Male 4/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Malaise Other Serious 3/28/2007 44 Male 185 lb 4/24/2007 Consumer United Kingdom
Primary
Concomitant
Pain Disability 2/14/2007 Male 5/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 67 Male 196 lb 12/13/2006 Consumer United States
Primary
Concomitant
Toxic Induced Encephalopathy Hospitalization 2/28/2007 Female 167 lb 6/9/2007 United States
Primary
Concomitant
Rash Generalised Other Serious 4/18/2007 Female 161 lb 6/18/2007 Consumer United Kingdom
Primary
Concomitant
Erythema Multiforme Hospitalization 5/27/2007 68 Male 6/20/2007 Consumer Italy
Primary
Concomitant
Rash Generalised Other Serious 4/18/2007 Female 161 lb 6/22/2007 Consumer United Kingdom
Primary
Concomitant
Malaise Other Serious 3/28/2007 44 Male 185 lb 7/12/2007 Consumer United Kingdom
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Male 7/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 8/5/2007 35 Female 294 lb 8/17/2007 Consumer United Kingdom
Primary
Concomitant
Paraesthesia Disability 67 Female 9/5/2007 Physician
Primary
Concomitant
Mouth Ulceration Disability 5/8/2007 89 Female 9/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Visual Disturbance Disability 2/19/2007 67 Female 181 lb 9/12/2007 Physician
Primary
Concomitant
Vomiting Hospitalization 8/11/2007 89 Female 9/14/2007 Other Health Professional France
Primary
Concomitant
Fall Hospitalization 7/18/2007 76 Female 238 lb 9/18/2007 Physician United Kingdom
Primary
Concomitant
Hypotension Life Threatening 7/18/2007 47 Female 126 lb 10/5/2007 Physician United States
Primary
Secondary
Concomitant
Rhinitis Other Serious 7/5/2007 10/10/2007 Consumer United Kingdom
Primary
Concomitant
Pleurisy Hospitalization 5/9/2007 Male 214 lb 10/11/2007 United Kingdom
Primary
Concomitant
Fall Hospitalization 7/18/2007 76 Female 238 lb 10/12/2007 Physician United Kingdom
Primary
Concomitant
Head Banging Hospitalization Male 10/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Cerebrovascular Accident Life Threatening 7/5/2007 72 Male 273 lb 10/31/2007 Consumer United Kingdom
Primary
Concomitant
Myocardial Infarction Other Serious 6/13/2006 11/5/2007 Consumer United Kingdom
Primary
Concomitant
Angina Pectoris Other Serious 11/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 6/13/2006 Female 11/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Sleep Disorder Hospitalization 6/1/2005 62 Male 11/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Fibrillation Life Threatening 11/20/2006 85 Female 11/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Head Banging Hospitalization 10/12/2007 Male 159 lb 11/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 11/20/2006 85 Female 11/22/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 10/12/2007 Male 159 lb 12/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Joint Swelling 8/19/2007 Male 165 lb 12/14/2007 United States
Primary
Concomitant
Syncope Other Serious 11/30/2007 76 Female 154 lb 12/28/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypotension Life Threatening 7/18/2007 47 Female 126 lb 2/6/2008 Physician United States
Primary
Secondary
Concomitant
Retinopathy Hospitalization 1/1/2006 58 Male 11/29/2007 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 9/1/2007 Male 114 lb 12/5/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 12/19/2007 71 Female 220 lb 2/19/2008 Consumer United Kingdom
Primary
Concomitant
Memory Impairment Disability 3/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Thinking Abnormal Other Serious 11/1/2007 Male 190 lb 3/25/2008 Consumer United States
Primary
Concomitant
Interacting
Skin Ulcer 78 Male 132 lb 8/30/2007 Physician United States
Primary
Concomitant
Irritability Other Serious 11/11/2007 54 Male 165 lb 3/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 3/12/2008 4/11/2008 Other Health Professional United Kingdom
Primary
Concomitant
Thinking Abnormal Other Serious 11/1/2007 Male 190 lb 4/16/2008 Consumer United States
Primary
Concomitant
Interacting
Influenza Like Illness Other Serious 3/1/2007 Female 187 lb 4/17/2008 Denmark
Primary
Concomitant
Rash Generalised Other Serious 4/18/2007 Female 161 lb 4/18/2008 Consumer United Kingdom
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/18/2008 United States
Primary
Concomitant
Tachycardia Hospitalization 2/20/2008 57 Male 4/21/2008 Sweden
Primary
Concomitant
Myocardial Ischaemia Life Threatening 8/30/2005 Male 139 lb 4/22/2008 United States
Primary
Concomitant
Cardio-respiratory Arrest Death 4/10/2008 69 Female 207 lb 4/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Blood Glucose Increased Other Serious 51 Male 151 lb 4/29/2008 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/30/2008 United States
Primary
Concomitant
Thinking Abnormal Other Serious 11/1/2007 Male 190 lb 4/30/2008 Consumer United States
Primary
Concomitant
Interacting
Disease Progression Death 69 Female 208 lb 5/2/2008 Consumer United Kingdom
Primary
Concomitant
Suicidal Ideation Male 190 lb 5/7/2008 Consumer United States
Primary
Concomitant
Interacting
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 5/9/2008 United States
Primary
Concomitant
Chest Pain Other Serious 3/1/2008 Female 194 lb 5/9/2008 Other Health Professional United Kingdom
Primary
Concomitant
Skin Ulcer 78 Male 132 lb 5/14/2008 Physician United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 5/15/2008 United States
Primary
Concomitant
Tongue Ulceration Hospitalization 1/10/2008 67 Female 5/13/2008 United Kingdom
Primary
Concomitant
Violence-related Symptom Other Serious 11/1/2007 Male 190 lb 5/30/2008 Consumer United States
Primary
Concomitant
Interacting
Syncope Hospitalization 10/12/2007 6/6/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Angina Unstable Hospitalization 7/5/2001 Male 194 lb 1/9/2009 Physician United States
Primary
Concomitant
Angina Unstable Hospitalization 7/5/2001 Male 194 lb 1/21/2009 Physician United States
Primary
Concomitant
Balance Disorder Hospitalization 1/16/2009 2/2/2009 Physician Sweden
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 4/1/2008 3/27/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/7/2009 4/23/2009 Physician Sweden
Primary
Secondary
Concomitant
Syncope Death 79 Female 5/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Hospitalization 7/21/2007 63 5/27/2009 Other Health Professional Singapore
Primary
Secondary
Concomitant
Presyncope Hospitalization 1/27/2009 51 Female 243 lb 5/20/2009 Australia
Primary
Concomitant
Pancreatitis Other Serious 55 Male 304 lb 6/2/2009 Physician United Kingdom
Primary
Concomitant
Muscle Necrosis Life Threatening 4/30/2009 77 Male 168 lb 6/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Myopathy Life Threatening 4/30/2009 77 Male 168 lb 6/22/2009
Primary
Concomitant
Renal Failure Acute Life Threatening 4/6/2009 85 Male 326 lb 7/1/2009 Other Health Professional United States
Primary
Concomitant
Left Ventricular Failure Other Serious 6/5/2009 67 7/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Obstructive Airways Disorder Other Serious 70 Male 7/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 91 Female 8/3/2009 Consumer United Kingdom
Primary
Concomitant
Left Ventricular Failure Other Serious 6/23/2009 67 8/3/2009 Other Health Professional United Kingdom
Primary
Concomitant
Left Ventricular Failure Other Serious 6/23/2009 67 8/7/2009 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Death 91 Female 8/6/2009 United Kingdom
Primary
Concomitant
Pulmonary Oedema Life Threatening 6/14/2009 72 Male 8/12/2009 Other Health Professional United States
Primary
Concomitant
Urosepsis Death 91 Female 8/19/2009 Consumer United Kingdom
Primary
Concomitant
Flushing 6/1/2008 Male 223 lb 8/21/2009 United States
Primary
Concomitant
Flushing Male 8/21/2009 United States
Primary
Concomitant
Urosepsis Death 91 Female 8/20/2009 United Kingdom
Primary
Concomitant
Cerebellar Infarction Death 73 8/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Lymphocyte Count Decreased Disability 1/4/2009 63 Male 154 lb 9/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Oedema Life Threatening 6/14/2009 72 Male 9/2/2009 Other Health Professional United States
Primary
Concomitant
Urosepsis Death 91 Female 9/4/2009 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 80 Male 9/15/2009 Physician United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 11/25/2005 57 Male 207 lb 9/23/2009 United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Disability 1/1/2008 64 Male 9/16/2009 Denmark
Primary
Secondary
Concomitant
Rhinitis Other Serious 7/5/2007 67 Male 9/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Disability 1/1/2008 64 Male 174 lb 10/13/2009 Denmark
Primary
Secondary
Concomitant
Presyncope Other Serious 9/15/2009 81 Female 10/22/2009 Other Health Professional United States
Primary
Concomitant
Nausea Hospitalization 86 Male 10/17/2009 Other Health Professional United States
Primary
Secondary
Memory Impairment Disability 79 Female 10/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Angina Pectoris Other Serious 78 Male 10/23/2009 United Kingdom
Primary
Concomitant
Syncope Death 1/6/2009 79 Female 10/23/2009 United Kingdom
Primary
Concomitant
Polyp Other Serious 2/4/2004 77 Female 11/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Polyp Other Serious 2/4/2004 77 Female 11/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Peritonitis Disability 1/1/2008 64 Male 174 lb 11/12/2009 Denmark
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 6/1/2009 78 Male 12/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Muscle Necrosis Life Threatening 4/30/2009 77 Male 168 lb 12/9/2009 Other Health Professional United Kingdom
Primary
Concomitant

Drug Data