Simvastatin combined with Tylenol-500

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Peritoneal Cloudy Effluent Other Serious 4/1/2009 69 Female 11/3/2009 Other Health Professional United States
Primary
Concomitant
Syncope Hospitalization 76 Male 1/13/2010 United States
Primary
Concomitant
Blood Pressure Increased Hospitalization Female 1/28/2010 Pharmacist United States
Primary
Concomitant
Sepsis Hospitalization 76 Male 1/19/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 Female 1/29/2010 Physician United States
Primary
Secondary
Concomitant
Prostatic Specific Antigen Increased Other Serious 3/1/2009 Male 119 lb 1/29/2010 Other Health Professional United States
Primary
Concomitant
Thrombosis Other Serious 1/1/2008 68 Male 2/4/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 2/1/2008 81 Female 2/4/2010 Lawyer United States
Primary
Concomitant
Vertigo Hospitalization 62 Male 187 lb 1/22/2010 United States
Primary
Concomitant
Breast Cancer In Situ Other Serious 12/22/2009 Female 117 lb 2/5/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2008 Female 232 lb 2/11/2010 Consumer United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization Female 2/11/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 Female 2/13/2010 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 2/2/2010 Male 159 lb 2/15/2010 Physician United States
Primary
Secondary
Concomitant
Pain Other Serious 5/6/2005 Female 2/17/2010 Other Health Professional Canada
Primary
Concomitant
Syncope Hospitalization Female 220 lb 2/19/2010 Consumer United States
Primary
Concomitant
Dehydration Hospitalization 5/20/2009 Male 180 lb 2/19/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Coronary Artery Occlusion Other Serious 1/1/2008 78 Female 135 lb 2/22/2010 Consumer United States
Primary
Concomitant
Vertigo Hospitalization 62 Male 187 lb 2/5/2010 United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2008 Female 232 lb 2/24/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 Female 3/2/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 2/10/2009 Female 3/2/2010 Physician
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 12/17/2009 91 Female 161 lb 2/2/2010 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cells Urine Positive Hospitalization 89 Female 2/19/2010 United States
Primary
Concomitant
Death Death 2/17/2010 Female 3/3/2010 Consumer United States
Primary
Concomitant
Syncope Hospitalization Female 220 lb 3/4/2010 Physician United States
Primary
Concomitant
Vascular Insufficiency Other Serious 10/1/2007 77 Female 3/4/2010 Lawyer United States
Primary
Concomitant
Sedation Other Serious 12/22/2009 Female 177 lb 3/4/2010 United States
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 2/1/2010 74 Female 3/8/2010 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 10/1/2009 69 Female 3/11/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 Female 3/12/2010 Physician United States
Primary
Concomitant
Splenomegaly Other Serious 1/11/2008 Male 3/12/2010 Physician United States
Primary
Concomitant
Pain Other Serious 5/6/2005 Female 3/14/2010 Other Health Professional Canada
Primary
Concomitant
Osteomyelitis Hospitalization 6/23/2009 78 Male 168 lb 3/16/2010 United States
Primary
Secondary
Concomitant
Hypercholesterolaemia Other Serious 10/14/2007 59 Female 3/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Colon Cancer Metastatic Death Female 3/17/2010 Physician United States
Primary
Concomitant
Walking Aid User Other Serious 5/1/2007 Male 219 lb 3/19/2010 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2004 Female 195 lb 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Duodenal Ulcer Haemorrhage Hospitalization 1/7/2010 76 Female 177 lb 1/10/2010 Pharmacist United States
Primary
Concomitant
Urinary Retention Other Serious 1/1/2009 81 Male 3/22/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 12/17/2007 73 Female 3/24/2010 Other Health Professional United States
Primary
Concomitant
Skin Disorder Other Serious 11/26/2007 Male 3/25/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 Female 3/26/2010 Physician United States
Primary
Concomitant
Pneumonia Other Serious 5/6/2005 Female 3/26/2010 Other Health Professional Canada
Primary
Concomitant
Walking Aid User Other Serious 5/1/2007 Male 219 lb 3/31/2010 United States
Primary
Secondary
Concomitant
Vasogenic Cerebral Oedema Other Serious 3/23/2010 59 Male 220 lb 4/2/2010 Physician United States
Primary
Concomitant
Lung Neoplasm Other Serious 6/1/2009 66 Female 255 lb 4/6/2010 Physician United States
Primary
Concomitant
Skin Ulcer Hospitalization 6/23/2009 78 Male 168 lb 4/6/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 58 Female 4/8/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/23/2007 45 Male 4/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urosepsis Hospitalization 3/24/2010 66 Male 154 lb 4/9/2010 Physician United States
Primary
Concomitant
Brain Oedema Other Serious 3/23/2010 59 Male 220 lb 4/13/2010 Physician United States
Primary
Concomitant
Wound Drainage Other Serious 1/1/2004 64 Female 195 lb 4/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 10/1/2007 84 Female 4/13/2010 Lawyer United States
Primary
Concomitant
Death Death 4/8/2010 69 Female 117 lb 4/14/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2008 64 Male 4/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 5/1/2007 68 Male 219 lb 4/15/2010 United States
Primary
Secondary
Concomitant
Tremor Hospitalization 2/21/2010 60 Male 279 lb 4/14/2010 Other Health Professional United States
Primary
Concomitant
Conjunctival Haemorrhage Other Serious 1/25/2010 63 Male 4/23/2010 Other Health Professional United States
Primary
Concomitant
Conjunctival Haemorrhage Other Serious 1/25/2010 63 Male 4/26/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 58 Female 4/27/2010 Physician United States
Primary
Concomitant
Urosepsis Hospitalization 3/24/2010 66 Male 154 lb 4/28/2010 Physician United States
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 2/1/2010 74 Female 4/29/2010 Pharmacist United States
Primary
Concomitant
Lung Neoplasm Other Serious 6/1/2009 66 Female 255 lb 4/30/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 58 Female 5/3/2010 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 1/1/2008 68 Male 5/3/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 5/2/2010 73 Female 5/3/2010 Pharmacist United States
Primary
Concomitant
Nausea Other Serious 81 Female 5/6/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 81 Female 5/7/2010 Other Health Professional United States
Primary
Concomitant
Respiratory Rate Increased Other Serious 8/20/2009 72 Female 176 lb 5/12/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Other Serious 5/6/2005 61 Female 5/13/2010 Other Health Professional Canada
Primary
Concomitant
Sepsis Other Serious 3/1/2010 70 Male 5/13/2010 Physician United States
Primary
Concomitant
Hip Fracture Hospitalization Female 240 lb 5/13/2010 Physician United States
Primary
Concomitant
Pneumonia Staphylococcal Death 64 Male 5/14/2010 Lawyer United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 6/22/2010 83 Female 7/27/2010 Physician United States
Primary
Concomitant
Tracheobronchitis Viral Other Serious Female 8/4/2010 Physician United States
Primary
Secondary
Concomitant
Medication Error Hospitalization 7/28/2010 71 Female 140 lb 8/4/2010 Physician United States
Primary
Concomitant
Tracheobronchitis Viral Other Serious Female 8/4/2010 Physician United States
Primary
Secondary
Concomitant
Myalgia 8/9/2009 77 Female 165 lb 8/27/2010 Consumer United States
Primary
Concomitant
Nausea 8/1/2009 80 Male 165 lb 8/27/2010 Consumer United States
Primary
Secondary
Concomitant
Flushing 1/1/2008 69 Male 215 lb 8/28/2010 United States
Primary
Concomitant
Speech Disorder Male 166 lb 8/28/2010 United States
Primary
Concomitant
Pruritus 4/19/2010 Male 176 lb 8/29/2010 United States
Primary
Concomitant
Pruritus Male 215 lb 8/29/2010 Consumer United States
Primary
Concomitant
Nausea 7/3/2010 56 Female 125 lb 8/29/2010 Consumer United States
Primary
Concomitant
Pruritus 7/14/2010 73 Female 160 lb 8/29/2010 Consumer United States
Primary
Concomitant
Pollakiuria 7/20/2010 65 Male 195 lb 8/29/2010 Consumer United States
Primary
Concomitant
Encephalopathy Hospitalization 7/7/2008 76 Female 286 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/10/2008 63 Male 205 lb 8/31/2010 Lawyer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/11/2006 69 Male 202 lb 8/28/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 58 Female 8/30/2010 Physician United States
Primary
Concomitant
Thrombosis Other Serious 10/1/2007 75 Male 9/2/2010 Lawyer United States
Primary
Concomitant
Syncope Other Serious 4/18/2010 60 Female 234 lb 9/3/2010
Primary
Secondary
Concomitant
Dysphagia Hospitalization 6/28/2010 78 Male 179 lb 10/18/2010 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 1/1/2008 86 Male 10/22/2010 Lawyer United States
Primary
Concomitant
Viral Infection Other Serious 7/31/2010 59 Male 195 lb 10/29/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 10/3/2006 52 Male 161 lb 12/2/2010 Other Health Professional United States
Primary
Concomitant
Vascular Graft Other Serious 5/1/1994 60 Male 12/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Decalcification Other Serious 7/1/2010 53 Female 146 lb 1/7/2011 Consumer Brazil
Primary
Secondary
Concomitant
Thyroid Neoplasm Hospitalization 6/24/2010 57 Female 187 lb 1/10/2011 Consumer United States
Primary
Concomitant
Paraesthesia Disability 1/26/2001 74 Male 186 lb 1/13/2011 United States
Primary
Concomitant
Bradycardia Disability Male 121 lb 1/18/2011 Physician United States
Primary
Concomitant
Ventricular Extrasystoles Death 86 Female 1/11/2011 United States
Primary
Concomitant
Multiple Sclerosis Relapse Other Serious 5/1/2010 64 Female 1/26/2011 Consumer United States
Primary
Concomitant
Hypotension Hospitalization 11/1/2010 62 Male 1/27/2011 Consumer United States
Primary
Concomitant
Nausea 8/26/2010 56 Male 1/29/2011 Consumer United States
Primary
Concomitant
Malaise 9/5/2010 62 Female 1/30/2011 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/21/2011 66 Female 2/2/2011
Primary
Concomitant
Depression Other Serious 3/23/2010 64 Female 2/4/2011 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/21/2011 66 Female 2/10/2011 Physician
Primary
Secondary
Concomitant
Sepsis Hospitalization 2/17/2011 65 Female 170 lb 2/25/2011 Other Health Professional United States
Primary
Concomitant
Heart Rate Irregular Other Serious 9/7/2006 81 Male 3/18/2011 Other Health Professional United States
Primary
Concomitant
Vertigo Other Serious 1/1/2007 76 Female 166 lb 3/18/2011 Other Health Professional United States
Primary
Concomitant
Breast Mass Hospitalization 5/6/2005 61 Female 3/18/2011 Physician Canada
Primary
Concomitant
Dyspnoea Disability 1/21/2011 66 Female 3/18/2011 Physician United States
Primary
Secondary
Concomitant
Asthenia Hospitalization 2/1/2011 58 Female 130 lb 5/2/2011 Consumer United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 4/16/2011 76 Male 163 lb 6/2/2011 Other Health Professional United States
Primary
Concomitant
Cardiomegaly Other Serious 1/1/2007 76 Female 166 lb 6/6/2011 United States
Primary
Concomitant
Device Related Infection Hospitalization 5/20/2011 72 Male 194 lb 6/7/2011 Physician United States
Primary
Concomitant
Bowel Movement Irregularity Other Serious Female 5/24/2011 Pharmacist Canada
Primary
Concomitant
Vomiting Other Serious 2/7/2011 6/16/2011 Physician United States
Primary
Concomitant
Anaemia Other Serious 1/1/2007 76 Female 166 lb 6/16/2011 United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 77 Female 243 lb 6/17/2011 Pharmacist United States
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2007 76 Female 166 lb 6/20/2011 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 12/25/2009 63 Female 6/22/2011 Consumer United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Life Threatening 77 Female 88 lb United States
Primary
Concomitant
Surgical Failure Other Serious 1/1/1999 58 Female 6/22/2011 Physician United States
Primary
Concomitant
Leukopenia Other Serious 2/8/2011 61 Female 6/22/2011 Pharmacist United States
Primary
Concomitant
Oedema Peripheral Other Serious 6/15/2011 Consumer United States
Primary
Concomitant
Rectal Polyp Hospitalization Female 155 lb 6/24/2011 Lawyer United States
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 10/2/2002 47 Female 128 lb 6/24/2011 Lawyer United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 2/20/2011 63 Male 192 lb 6/27/2011 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Infection Other Serious Male 6/27/2011 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 79 Female 6/20/2011 Lawyer United States
Primary
Concomitant
Haemorrhoids Hospitalization Female 155 lb 6/30/2011 Lawyer United States
Primary
Secondary
Concomitant
Fall Hospitalization 4/7/2011 87 Female 110 lb 7/1/2011 Other Health Professional United States
Primary
Concomitant
Laceration Other Serious 1/1/1999 58 Female 7/8/2011 Lawyer United States
Primary
Concomitant
Brain Oedema Other Serious 3/23/2010 59 Male 220 lb 7/11/2011 Physician United States
Primary
Concomitant
Death Death 1/1/2011 63 Male 7/13/2011 Physician United States
Primary
Concomitant
Cerebral Atrophy Hospitalization 1/15/2011 75 Female 140 lb 7/18/2011 Pharmacist United States
Primary
Concomitant
Abdominal Pain Upper Other Serious 7/15/2011 78 Female 7/19/2011 Consumer United States
Primary
Concomitant
Anaemia Hospitalization 5/20/2011 72 Male 194 lb 7/25/2011 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2010 71 Female 7/25/2011 Consumer United States
Primary
Concomitant
Mitral Valve Incompetence Other Serious 5/1/2007 68 Male 219 lb 7/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Myopia Other Serious 10/2/2002 47 Female 128 lb 7/25/2011 United States
Primary
Secondary
Concomitant
Dysmorphism Other Serious 1/1/2007 72 Male 7/26/2011 Consumer United States
Primary
Concomitant
Anaemia Hospitalization Female 7/29/2011 Lawyer United States
Primary
Secondary
Concomitant
Headache Other Serious 5/6/2005 61 Female 7/29/2011 Physician Canada
Primary
Concomitant
Blood Creatinine Increased Hospitalization 11/24/2000 71 Female 153 lb 7/29/2011 Consumer United States
Primary
Concomitant
Toxicity To Various Agents Death 7/15/2011 96 Male 163 lb 7/28/2011 Pharmacist United States
Primary
Concomitant

Drug Data