Simvastatin combined with Tizanidine Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Dry Mouth Other Serious 4/3/2006 62 Male 207 lb 4/7/2006 Pharmacist United States
Primary
Concomitant
Cardiac Arrest Required Intervention 6/15/2006 63 Male 223 lb 6/15/2006 Pharmacist United States
Primary
Concomitant
Ileus Paralytic Life Threatening 4/1/2006 85 Female 8/29/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ileus Paralytic Life Threatening 4/1/2006 85 Female 9/6/2006 United Kingdom
Primary
Secondary
Concomitant
Ileus Paralytic Other Serious 4/1/2006 85 Female 9/7/2006 Denmark
Primary
Concomitant
Pruritus Required Intervention 9/21/2006 64 Male 171 lb 9/21/2006 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 10/10/2006 50 Male 159 lb 11/29/2006 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious 42 Male 11/13/2006 Physician United States
Primary
Concomitant
Toxic Induced Encephalopathy Hospitalization 2/28/2007 Female 167 lb 6/9/2007 United States
Primary
Concomitant
Yawning Life Threatening 3/28/2007 Female 162 lb 6/30/2007 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 1/1/2007 79 Male 10/12/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/11/2003 47 Female 261 lb 1/18/2008 Physician United States
Primary
Concomitant
Retching 12/26/2007 49 Female 2/16/2008 United States
Primary
Concomitant
Retching 12/26/2007 49 Female 2/27/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 50 Female 3/3/2008 United States
Primary
Concomitant
Interacting
Renal Impairment Other Serious 50 Female 3/21/2008 Physician United States
Primary
Concomitant
Interacting
White Blood Cell Count Increased Required Intervention 50 Female 3/19/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 50 Female 4/23/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 50 Female 5/2/2008 Other Health Professional Germany
Primary
Concomitant
Interacting
Renal Injury Other Serious 50 Female 4/25/2008 United States
Primary
Secondary
Renal Impairment Hospitalization 1/1/2008 50 Female 5/28/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased 12/1/2007 60 Male 295 lb 4/10/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 50 Female 6/27/2008 Physician United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 50 Female 7/28/2008 Physician United States
Primary
Concomitant
Renal Injury Hospitalization 50 Female 9/12/2008 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 50 Female 10/7/2008 Physician United States
Primary
Secondary
Concomitant
Ileus Paralytic Other Serious 4/1/2006 85 Female 10/22/2008 Denmark
Primary
Concomitant
Weight Decreased Other Serious 9/11/2003 47 Female 260 lb 11/10/2008 United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 50 Female 12/30/2008 Physician United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 1/25/2009 36 Male 3/3/2009 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Death 12/19/2008 80 Male 149 lb 3/4/2009 Physician Japan
Primary
Secondary
Concomitant
Movement Disorder Other Serious 10/1/2006 38 Female 180 lb 4/1/2009 United States
Primary
Concomitant
Pneumonia Other Serious 4/23/2009 44 Female 271 lb 5/5/2009 United States
Primary
Concomitant
Cardiac Pacemaker Insertion Other Serious 1/1/2008 53 Male 6/3/2009 Physician United States
Primary
Concomitant
Tongue Injury Hospitalization 4/15/2009 53 Male 163 lb 6/4/2009 Physician United States
Primary
Concomitant
Traumatic Brain Injury Other Serious 1/1/2003 40 Male 209 lb 7/23/2009 United States
Primary
Concomitant
Weight Decreased Death 73 Female 8/28/2009 United States
Primary
Concomitant
Injury Death 64 Female 9/10/2009 Lawyer United States
Primary
Concomitant
Vomiting 3/1/2004 42 Female 200 lb 9/23/2009 United States
Primary
Concomitant
Ileus Paralytic Life Threatening 4/1/2006 85 Female 9/16/2009 United Kingdom
Primary
Concomitant
Swelling Other Serious 12/1/2008 Male 275 lb 10/14/2009 Consumer United States
Primary
Concomitant
Weight Decreased Death 73 Female 11/5/2009 United States
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 8/1/2009 73 Female 11/19/2009 Physician United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 50 Female 12/7/2009 Physician United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 1/25/2009 36 Male 2/4/2010 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 1/1/2003 Female 2/25/2010 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 4/8/2010 78 Female 150 lb 4/23/2010 Consumer United States
Primary
Concomitant
Memory Impairment 38 Female 218 lb 4/30/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 12/18/2008 80 Male 149 lb 6/23/2010 Physician Japan
Primary
Secondary
Concomitant
Somnolence Other Serious 1/1/2010 41 Female 7/16/2010 Other Health Professional Netherlands
Primary
Concomitant
Vomiting 10/1/2007 Female 133 lb 7/17/2010 Consumer United States
Primary
Concomitant
Restlessness Other Serious 1/1/2008 60 Female 187 lb 7/29/2010 Consumer United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 1/1/2010 41 Female 8/11/2010 Other Health Professional Netherlands
Primary
Concomitant
Skin Warm 6/1/2010 60 Female 175 lb 8/29/2010 Consumer United States
Primary
Concomitant
Sudden Onset Of Sleep 10/1/2009 63 Female 188 lb 9/7/2010 Other Health Professional
Primary
Concomitant
Pharyngeal Oedema Other Serious 3/1/2010 52 Female 9/17/2010 Physician United States
Primary
Concomitant
Vomiting Hospitalization 8/1/2010 49 Female 359 lb 9/24/2010 Physician United States
Primary
Concomitant
Hypotension Other Serious 9/3/2010 56 Female 200 lb 10/4/2010 Consumer United States
Primary
Concomitant
Hypotension Other Serious 9/3/2010 56 Female 209 lb 10/22/2010 Physician United States
Primary
Concomitant
Sinus Bradycardia Hospitalization 85 Male 10/15/2010 United States
Primary
Secondary
Concomitant
Pharyngeal Oedema Other Serious 3/1/2010 52 Female 10/22/2010 Physician United States
Primary
Concomitant
Oedema Peripheral 10/29/2010 51 Male 11/1/2010 Pharmacist United States
Primary
Concomitant
Condition Aggravated Hospitalization 8/1/2010 42 Female 1/11/2011 Other Health Professional Netherlands
Primary
Concomitant
Joint Instability Hospitalization 11/11/2010 59 Female 157 lb 1/17/2011 Other Health Professional United States
Primary
Concomitant
Drug Interaction Hospitalization 85 Male 3/17/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Road Traffic Accident Other Serious 12/1/2010 63 Male 270 lb 4/6/2011 Consumer United States
Primary
Concomitant
Sepsis Other Serious 1/1/2010 42 Female 4/1/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 82 Female 5/2/2011 Physician United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 2/1/2011 59 Female 5/27/2011 Physician United States
Primary
Concomitant
Vitamin D Abnormal Other Serious 1/1/2008 47 Female 6/7/2011 Consumer Brazil
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 2/1/2011 59 Female 6/15/2011 Other Health Professional United States
Primary
Concomitant
Joint Instability Hospitalization 11/11/2010 59 Female 157 lb 6/20/2011 Consumer United States
Primary
Concomitant
Subcutaneous Haematoma Death 2/1/2011 59 Female 6/23/2011 Physician United States
Primary
Concomitant
Chest Discomfort Female 7/1/2011 Pharmacist United States
Primary
Concomitant
Drug Interaction Other Serious 1/1/2010 47 Female 206 lb 7/5/2011 Consumer United States
Primary
Concomitant
Interacting
Joint Instability Hospitalization 11/11/2010 59 Female 157 lb 7/7/2011 Other Health Professional United States
Primary
Concomitant
Viral Infection Hospitalization 5/1/2011 52 Female 7/11/2011 Physician United States
Primary
Concomitant
Posture Abnormal Hospitalization 11/12/2010 71 Male 7/13/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Multiple Sclerosis Relapse 11/1/2010 50 Female 7/15/2011 Physician United States
Primary
Concomitant
Herpes Zoster 11/1/2010 50 Female 7/19/2011 Consumer United States
Primary
Concomitant
Hostility Other Serious 48 Female 206 lb 7/22/2011 Consumer United States
Primary
Concomitant
Interacting
Pancreatitis Acute Other Serious Male 7/25/2011 Consumer United States
Primary
Concomitant
Initial Insomnia Other Serious 1/1/2009 39 Female 232 lb 7/13/2011 Consumer United States
Primary
Concomitant
Petechiae Female 189 lb 8/6/2011 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 6/24/2011 58 Female 8/10/2011 Physician United States
Primary
Secondary
Concomitant
Vertigo Other Serious 12/20/2010 53 Female 8/23/2011 Consumer United States
Primary
Concomitant
Pain 6/1/2011 Female 144 lb 9/6/2011 Other Health Professional United States
Primary
Concomitant
Blood Potassium Increased Hospitalization 85 Male 8/31/2011 Other Health Professional United States
Primary
Concomitant
Subcutaneous Haematoma Hospitalization 2/1/2011 59 Female 9/9/2011 Physician United States
Primary
Concomitant
Multiple Sclerosis Relapse Hospitalization 5/1/2011 52 Female 9/12/2011 Consumer United States
Primary
Concomitant
Anxiety 10/1/2009 63 Female 188 lb 9/19/2011 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Hospitalization 6/24/2011 58 Female 9/20/2011 Physician United States
Primary
Secondary
Concomitant
Diarrhoea Infectious Other Serious 6/24/2011 58 Female 9/27/2011 Physician United States
Primary
Secondary
Concomitant
Injection Site Necrosis Hospitalization 8/1/2011 51 Male 174 lb 10/3/2011 Pharmacist United States
Primary
Concomitant
Cholecystectomy Hospitalization 6/1/2010 27 Female 205 lb 10/4/2011 Lawyer United States
Primary
Secondary
Concomitant
Multiple Sclerosis Relapse Hospitalization 5/1/2011 52 Female 10/5/2011 Physician United States
Primary
Concomitant
Off Label Use Female 245 lb 10/7/2011 Consumer United States
Primary
Concomitant
Hypotension Other Serious 6/24/2011 58 Female 10/14/2011 Physician United States
Primary
Secondary
Concomitant
Injection Site Pain Hospitalization 8/1/2011 51 Male 174 lb 10/19/2011 Pharmacist United States
Primary
Concomitant
Expired Drug Administered Other Serious 1/1/2009 56 Male 250 lb 10/25/2011 Consumer United States
Primary
Concomitant
Cervical Vertebral Fracture Life Threatening 6/24/2011 58 Female 10/27/2011 Physician United States
Primary
Secondary
Concomitant
Bronchitis 12/14/2010 60 Female 175 lb 10/28/2011 Consumer United States
Primary
Concomitant
Homicidal Ideation Other Serious 1/1/2010 47 Female 206 lb 10/31/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Multiple Sclerosis 8/1/2011 62 Female 141 lb 11/3/2011 Other Health Professional United States
Primary
Concomitant
Cholecystectomy Other Serious 6/1/2010 28 Female 205 lb 11/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Fatigue Other Serious Female 11/10/2011 Physician United States
Primary
Concomitant
Pneumonia Other Serious 11/1/2011 75 Male 149 lb 11/15/2011 United States
Primary
Concomitant
Multiple Sclerosis Hospitalization 1/1/2011 62 Female 141 lb 11/17/2011 Other Health Professional United States
Primary
Concomitant
Blood Pressure Fluctuation Other Serious 1/1/2008 57 Male 183 lb 11/18/2011 Consumer United States
Primary
Concomitant
Gastrointestinal Candidiasis Disability 6/24/2011 58 Female 11/21/2011 Physician United States
Primary
Secondary
Concomitant
Multiple Sclerosis Hospitalization 1/1/2011 62 Female 141 lb 11/23/2011 United States
Primary
Concomitant
Dyspepsia 42 Male 11/22/2011 Consumer United States
Primary
Concomitant
Cholecystitis Chronic Hospitalization 6/1/2010 28 Female 205 lb 11/28/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Other Serious 8/16/2011 53 Female 9/8/2011 Other Health Professional United States
Primary
Concomitant
Syncope Hospitalization 6/24/2011 58 Female 12/7/2011 Physician United States
Primary
Secondary
Concomitant
Medication Error 3/31/2011 51 Female 200 lb 9/8/2011 Consumer United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 1/1/2011 62 Female 141 lb 12/12/2011 United States
Primary
Concomitant
Immune Reconstitution Syndrome Other Serious 1/1/2011 62 Female 141 lb 12/21/2011 Physician United States
Primary
Concomitant
Immune Reconstitution Syndrome Other Serious 1/1/2011 62 Female 141 lb 12/21/2011 Other Health Professional United States
Primary
Concomitant
Dyspnoea 9/11/2011 59 Male 265 lb 12/20/2011 Consumer United States
Primary
Concomitant
Atelectasis Other Serious 71 Male 12/14/2011 Lawyer United States
Primary
Concomitant
Multiple Sclerosis Hospitalization 1/1/2011 37 Female 91 lb 12/28/2011 Physician Japan
Primary
Concomitant
Pancreatitis Acute Other Serious Male 11/17/2011 Lawyer United States
Primary
Concomitant
Lymphoma Other Serious 1/1/2011 37 Female 91 lb 1/9/2012 Physician Japan
Primary
Concomitant
Asthenia Other Serious 53 Female 150 lb 1/10/2012 Consumer United States
Primary
Concomitant
Multiple Sclerosis Other Serious 1/1/2011 37 Female 91 lb 1/17/2012 Physician Japan
Primary
Concomitant
Lymphoma Other Serious 10/27/2011 38 Female 91 lb 1/17/2012 Physician Japan
Primary
Concomitant
Fatigue Other Serious 53 Female 150 lb 1/18/2012 Consumer United States
Primary
Concomitant
Cervical Vertebral Fracture Hospitalization 6/24/2011 58 Female 165 lb 1/23/2012 Physician United States
Primary
Secondary
Concomitant
Sinus Bradycardia Hospitalization 85 Male 1/13/2012 Pharmacist United States
Primary
Secondary
Concomitant
Breath Sounds Abnormal Other Serious 11/1/2011 75 Male 149 lb 1/24/2012 Physician United States
Primary
Concomitant
Multiple Sclerosis Other Serious 10/27/2011 38 Female 91 lb 1/24/2012 Physician Japan
Primary
Concomitant
Rash Erythematous 6/1/2011 Female 144 lb 1/24/2012 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 53 Female 150 lb 1/27/2012 Physician United States
Primary
Concomitant
Skin Lesion 1/1/2008 52 Female 150 lb 1/27/2012 Consumer United States
Primary
Secondary
Concomitant
Skin Infection 8/1/2010 63 Female 130 lb 1/27/2012 Consumer United States
Primary
Concomitant
Arthralgia 2/1/2011 63 Female 175 lb 1/28/2012 Consumer United States
Primary
Concomitant
Family Stress Disability Male 1/20/2012 Lawyer United States
Primary
Secondary
Concomitant
Wound Secretion 3/1/2011 57 Male 220 lb 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Urticaria 53 Female 1/28/2012 Consumer United States
Primary
Concomitant
Cystitis 10/1/2011 50 Female 1/28/2012 Consumer United States
Primary
Concomitant
Blood Calcium Increased Other Serious 6/1/2011 75 Female 2/6/2012 Consumer United States
Primary
Concomitant
Feeling Abnormal Other Serious 11/21/2011 66 Male 2/6/2012 Pharmacist United States
Primary
Concomitant
Multiple Sclerosis Other Serious 10/27/2011 38 Female 91 lb 2/13/2012 Physician Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2001 66 Male 2/14/2012 Physician United States
Primary
Concomitant
Diffuse Large B-cell Lymphoma Other Serious 10/27/2011 38 Female 91 lb 2/21/2012 Physician Japan
Primary
Concomitant
Hallucination 59 Female 2/22/2012 Consumer United States
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Other Serious 11/1/2011 38 Female 91 lb 2/22/2012 Physician Japan
Primary
Concomitant
Dyspepsia 42 Male 2/29/2012 Consumer United States
Primary
Secondary
Nausea Other Serious 53 Female 150 lb 3/9/2012 Consumer United States
Primary
Concomitant

Drug Data