Simvastatin combined with Sinemet

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tricuspid Valve Sclerosis Other Serious 1/1/2004 58 Male 4/25/2006 Denmark
Primary
Concomitant
Vitamin B12 Deficiency Hospitalization 2/12/2006 Female 12/1/2006 Physician Australia
Primary
Concomitant
Oedema 53 Male 159 lb 1/11/2007 Physician United Kingdom
Primary
Concomitant
Subdural Haematoma Life Threatening 2/19/2007 85 Female 2/26/2007 Pharmacist United States
Primary
Secondary
Concomitant
Sensory Disturbance Hospitalization 11/1/2006 53 Male 159 lb 3/30/2007 Physician United Kingdom
Primary
Concomitant
Anaemia Hospitalization 1/11/2007 68 Male 5/10/2007 Pharmacist United States
Primary
Secondary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 12/1/2002 75 Male 201 lb 5/25/2007 Physician United States
Primary
Concomitant
Infection Other Serious 75 Female 5/31/2007 Consumer Brazil
Primary
Concomitant
Osteoporosis Other Serious 1/1/2006 75 Female 93 lb 6/12/2007 Consumer Brazil
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 12/1/2002 75 Male 201 lb 10/8/2007 Physician United States
Primary
Concomitant
Infection Other Serious 9/17/2007 Female 159 lb 10/17/2007 Czech Republic
Primary
Concomitant
Parkinson's Disease Other Serious 10/1/2006 Female 159 lb 12/13/2007 Czech Republic
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 86 Male 11/7/2007 United States
Primary
Secondary
Concomitant
Sudden Death Death 1/1/2003 Male 2/22/2008 Physician Norway
Primary
Concomitant
Diarrhoea Hospitalization 79 Male 3/13/2008 Other Health Professional Finland
Primary
Concomitant
Colitis Hospitalization 79 Male 3/5/2008 Sweden
Primary
Concomitant
Sudden Death Death 1/1/2003 Male 4/3/2008 Physician Norway
Primary
Concomitant
No Adverse Event Death 12/21/2006 Male 4/8/2008 Physician Norway
Primary
Concomitant
Wrong Technique In Drug Usage Process 3/1/2008 84 Male 4/24/2008 United States
Primary
Concomitant
Vitreous Floaters Male 210 lb 5/15/2008 Physician United States
Primary
Concomitant
Somnolence Other Serious 6/19/2008 76 Male 7/17/2008 Other Health Professional United Kingdom
Primary
Concomitant
Somnolence Other Serious 6/19/2008 76 Male 8/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gastrostomy Tube Insertion Hospitalization Male 10/2/2008 Physician Finland
Primary
Concomitant
Diarrhoea Hospitalization 78 Male 10/10/2008 United Kingdom
Primary
Concomitant
Gastrostomy Tube Insertion Hospitalization 1/1/2006 Male 10/21/2008 Physician Finland
Primary
Concomitant
Unresponsive To Stimuli Other Serious 7/15/2008 Male 10/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Onset Of Sleep Other Serious 7/15/2008 83 Male 10/17/2008 United Kingdom
Primary
Concomitant
Confusional State Death 80 Male 123 lb 10/29/2008 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Onset Of Sleep Other Serious 7/15/2008 83 Male 10/30/2008 United Kingdom
Primary
Concomitant
Sudden Onset Of Sleep Other Serious 7/15/2008 Male 11/6/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rash Erythematous Hospitalization 11/27/2008 70 Male 194 lb 1/9/2009 Consumer United States
Primary
Concomitant
Mental Status Changes Other Serious 11/18/2008 Male 143 lb 1/22/2009 Physician United States
Primary
Concomitant
Pallor Hospitalization 1/18/2009 81 Male 2/20/2009 New Zealand
Primary
Concomitant
Parkinson's Disease 10/1/2005 3/12/2009 Other Health Professional United States
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 2/6/2009 Male 132 lb 3/19/2009 Physician United Kingdom
Primary
Concomitant
Tremor Other Serious 3/9/2009 86 Female 132 lb 3/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Verbal Abuse Other Serious 3/14/2009 66 Male 205 lb 4/12/2009 Consumer United States
Primary
Concomitant
Joint Swelling Other Serious 12/1/2008 85 127 lb 4/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Joint Swelling Other Serious 12/1/2008 85 127 lb 4/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vitamin B12 Increased Hospitalization 1/18/2009 81 Male 4/28/2009 New Zealand
Primary
Concomitant
Pyrexia Other Serious 4/24/2009 53 Male 5/18/2009 Other Health Professional Italy
Primary
Concomitant
Fatigue Hospitalization 62 Male 188 lb 5/22/2009 Pharmacist United States
Primary
Concomitant
Pyrexia Other Serious 4/24/2009 Male 6/4/2009 Other Health Professional Italy
Primary
Concomitant
Oral Candidiasis Other Serious 2/6/2009 Male 132 lb 7/13/2009 Physician United Kingdom
Primary
Concomitant
Rib Fracture Disability 6/1/2009 74 Male 7/23/2009 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 4/24/2009 Male 7/30/2009 Other Health Professional Italy
Primary
Concomitant
Pseudomembranous Colitis Hospitalization 11/7/2008 Male 129 lb 8/6/2009 Physician Belgium
Primary
Concomitant
Weight Increased Other Serious Female 8/28/2009 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 8/19/2009 Male 181 lb 9/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/19/2009 Male 181 lb 9/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Parkinson's Disease Disability Male 10/5/2009 Consumer United States
Primary
Concomitant
Pseudomembranous Colitis Hospitalization 11/7/2008 Male 129 lb 10/23/2009 Physician Belgium
Primary
Concomitant
Pseudomembranous Colitis Other Serious 11/7/2008 Male 129 lb 11/12/2009 Physician Belgium
Primary
Concomitant
Pseudomembranous Colitis Other Serious 11/7/2008 Male 129 lb 12/3/2009 Physician Belgium
Primary
Concomitant
Pseudomembranous Colitis Other Serious 11/7/2008 Male 129 lb 12/10/2009 Physician Belgium
Primary
Concomitant
Pruritus Other Serious 10/1/2009 60 Male 265 lb 12/12/2009 Other Health Professional
Primary
Concomitant
Sinus Tachycardia Other Serious 10/1/2009 80 Male 12/8/2009 Physician Spain
Primary
Concomitant
Renal Failure Acute Hospitalization 8/19/2009 Male 167 lb 12/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/19/2009 Male 167 lb 12/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sinus Tachycardia 10/27/2009 80 Male 12/24/2009 Spain
Primary
Concomitant
Parkinson's Disease Other Serious 2/1/2010 80 Female 182 lb 2/8/2010 Physician United States
Primary
Concomitant
Pruritus Other Serious 10/1/2009 60 Male 265 lb 2/25/2010 Other Health Professional
Primary
Concomitant
Gambling 60 Male 261 lb 3/5/2010 Pharmacist United States
Primary
Secondary
Concomitant
Sleep Attacks Other Serious 58 Female 3/16/2010 Consumer United States
Primary
Secondary
Concomitant
Parkinson's Disease Other Serious 1/1/2010 78 Male 7/1/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 5/1/2010 62 Male 331 lb 7/6/2010 Pharmacist United States
Primary
Concomitant
Alopecia 1/1/2009 72 Female 90 lb 2/4/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 5/1/2010 62 Male 331 lb 7/8/2010 Pharmacist United States
Primary
Concomitant
Dysgeusia 1/1/2007 55 Male 200 lb 7/17/2010 Other Health Professional United States
Primary
Concomitant
Somnolence Hospitalization Male 8/2/2010 Physician United Kingdom
Primary
Concomitant
Treatment Noncompliance 8/16/2010 57 Male 290 lb 8/27/2010 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization Female 280 lb 9/3/2010 Consumer United States
Primary
Concomitant
Vomiting 67 Female 9/1/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 5/1/2010 62 Male 331 lb 9/7/2010 Pharmacist United States
Primary
Concomitant
Hypotension Hospitalization 7/13/2010 75 Male 9/13/2010 Physician Hong Kong
Primary
Secondary
Concomitant
Death Death Male 187 lb 9/15/2010 Consumer Brazil
Primary
Concomitant
Somnolence Hospitalization 7/14/2010 76 Male 9/28/2010 Physician United Kingdom
Primary
Concomitant
Pain Hospitalization 8/6/2010 60 Female 170 lb 9/24/2010 Physician United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 8/6/2010 60 Female 170 lb 10/8/2010 Other Health Professional United States
Primary
Concomitant
Vascular Dementia Hospitalization 6/28/2010 72 Male 200 lb 10/15/2010 United States
Primary
Secondary
Concomitant
Cardiac Failure Death 3/5/2010 10/28/2010 Physician United States
Primary
Concomitant
Weight Increased Hospitalization Female 280 lb 11/8/2010 Physician United States
Primary
Concomitant
Right Ventricular Hypertrophy Hospitalization 7/1/2010 11/22/2010 Other Health Professional United States
Primary
Concomitant
Oral Candidiasis Other Serious 2/6/2009 76 Male 132 lb 11/29/2010 Physician United Kingdom
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 11/21/2010 56 Male 12/9/2010 Physician United States
Primary
Secondary
Concomitant
Death Death Male 187 lb 2/22/2011 Consumer Brazil
Primary
Concomitant
Suicide Attempt Hospitalization 1/13/2011 68 Male 3/16/2011 Sweden
Primary
Concomitant
Blood Glucose Decreased Hospitalization 4/6/2010 84 Female 3/22/2011 Pharmacist United States
Primary
Concomitant
Dysphagia Hospitalization 1/1/2008 60 Female 4/5/2011 Physician Norway
Primary
Concomitant
Nervous System Disorder Hospitalization 1/1/2008 60 Female 4/11/2011 Physician Norway
Primary
Concomitant
Wrong Drug Administered Hospitalization 1/1/2011 66 Male 4/15/2011 Other Health Professional Spain
Primary
Concomitant
Pneumonia Hospitalization 7/1/2010 4/18/2011 Other Health Professional United States
Primary
Concomitant
Dizziness Hospitalization 4/17/2011 61 Male 4/28/2011 Consumer United States
Primary
Concomitant
Completed Suicide Death Female 5/4/2011 Physician New Zealand
Primary
Concomitant
Fatigue Hospitalization 4/1/2011 82 Female 161 lb 5/16/2011 Other Health Professional United States
Primary
Concomitant
Drug Administration Error Hospitalization 79 Female 5/24/2011 Physician Finland
Primary
Secondary
Concomitant
Drug Administration Error Hospitalization 79 Female 5/31/2011 Finland
Primary
Secondary
Concomitant
Pulmonary Thrombosis Hospitalization Female 6/13/2011 United States
Primary
Concomitant
Kidney Infection Hospitalization Female 6/21/2011 Consumer United States
Primary
Concomitant
Squamous Cell Carcinoma 6/1/2011 69 Male 140 lb 7/6/2011 Physician United States
Primary
Concomitant
Acute Myocardial Infarction Life Threatening 7/5/2011 85 Female 111 lb 7/7/2011 Physician United States
Primary
Concomitant
Ventricular Hypokinesia Other Serious 6/30/2011 73 Female 8/12/2011 Consumer Spain
Primary
Concomitant
Ejection Fraction Decreased Other Serious 6/30/2011 73 Female 8/21/2011 Consumer Spain
Primary
Concomitant
Blood Glucose Increased Other Serious 7/1/2010 72 Female 111 lb 8/31/2011 Lawyer United States
Primary
Concomitant
Gastritis Haemorrhagic Hospitalization 7/10/2011 74 9/13/2011 Physician Sweden
Primary
Concomitant
Gastritis Haemorrhagic Hospitalization 7/10/2011 74 9/21/2011 Physician Sweden
Primary
Concomitant
Off Label Use 5/2/2006 71 Male 9/23/2011 Physician Canada
Primary
Secondary
Concomitant
Impulse-control Disorder Other Serious 6/1/2011 72 Male 10/14/2011 Other Health Professional France
Primary
Secondary
Concomitant
Gait Disturbance Other Serious Male 10/17/2011 Other Health Professional France
Primary
Concomitant
Impulse-control Disorder Other Serious 6/1/2011 72 Male 10/18/2011 Other Health Professional France
Primary
Secondary
Concomitant
Subdural Haematoma Other Serious 73 Male 198 lb 10/20/2011 Consumer United States
Primary
Secondary
Concomitant
Anaemia Hospitalization 9/9/2011 73 Male 198 lb 10/24/2011 Consumer United States
Primary
Secondary
Concomitant
Anaemia Other Serious 9/9/2011 73 Male 198 lb 10/25/2011 Consumer United States
Primary
Secondary
Concomitant
Immobile Disability 10/1/2011 70 11/10/2011 Pharmacist Australia
Primary
Concomitant
Gait Disturbance 11/1/2011 76 Male 11/21/2011 Consumer United States
Primary
Concomitant
Malignant Melanoma Other Serious 11/1/2011 80 Female 202 lb 12/12/2011 Physician United States
Primary
Concomitant
Wrist Fracture Hospitalization 1/1/2011 65 Female 127 lb 12/13/2011 Physician United States
Primary
Concomitant
Speech Disorder Disability 10/1/2011 70 12/21/2011 Pharmacist Australia
Primary
Concomitant
Lethargy 11/1/2011 76 Male 1/10/2012 Consumer United States
Primary
Concomitant
Exfoliative Rash Other Serious 1/1/2012 57 Female 118 lb 2/3/2012 Consumer United States
Primary
Secondary
Concomitant
Headache 2/1/2012 70 Male 3/1/2012 Consumer United States
Primary
Concomitant
Off Label Use Other Serious 68 Female 3/15/2012 Consumer United Kingdom
Primary
Concomitant
Tremor Hospitalization Female 198 lb 3/26/2012 Lawyer United States
Primary
Concomitant
Dizziness 2/1/2012 70 Male 4/4/2012 Physician United States
Primary
Concomitant
Nausea Other Serious 1/1/2009 75 Female 4/16/2012 Consumer United States
Primary
Concomitant
Malignant Melanoma Other Serious 11/10/2011 80 Female 202 lb 5/2/2012 Physician United States
Primary
Concomitant
Hallucination Other Serious 76 Male 2/10/2010 Consumer United States
Primary
Concomitant
Feeling Abnormal Other Serious 12/21/2009 76 Male 5/5/2010 Physician United States
Primary
Concomitant
Middle Insomnia Other Serious Male 5/5/2010 Consumer United States
Primary
Secondary
Concomitant
Blood Pressure Increased Other Serious 2/1/2011 69 Female 2/7/2012 Physician United States
Primary
Concomitant
Application Site Erythema Other Serious 2/1/2011 69 Female 2/7/2012 Physician United States
Primary
Concomitant
Rash 5/20/2012 69 Male 150 lb 5/30/2012 Consumer United States
Primary
Concomitant
Incorrect Dose Administered Other Serious 68 Female 5/31/2012 Consumer United Kingdom
Primary
Concomitant
Hyperproteinaemia Other Serious 3/20/2011 87 Male 3/24/2011 Physician United States
Primary
Concomitant
Vomiting Disability 60 Female 6/14/2012 Physician United States
Primary
Secondary
Concomitant
Dermatitis Exfoliative Other Serious 5/21/2012 69 Male 150 lb 6/18/2012 Physician United States
Primary
Concomitant
Affective Disorder Other Serious 8/25/2010 72 Female 170 lb 6/14/2012 Lawyer United States
Primary
Concomitant
Cardiac Failure Congestive Death 1/8/2012 80 Male 6/28/2012 Pharmacist United States
Primary
Concomitant
Clavicle Fracture Other Serious 1/1/2011 65 Female 127 lb 7/25/2012 Physician United States
Primary
Concomitant
Feeling Abnormal Other Serious 76 Male 2/10/2010 Consumer United States
Primary
Concomitant
Somnolence Other Serious 1/1/2007 7/31/2012 Consumer United States
Primary
Secondary
Concomitant
Blood Creatinine Increased Hospitalization 4/9/2012 78 Male 125 lb 8/13/2012 Pharmacist United States
Primary
Concomitant
Respiratory Failure Hospitalization 7/2010 65 Male 1/11/2013 Other Health Professional Us
Primary
Concomitant
Progressive Supranuclear Palsy Other Serious 2008 60 Female 10/24/2012 Physician No
Primary
Concomitant
Wrist Fracture Other Serious 2011 Female 127 lb 1/23/2013 Other Health Professional Us
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 7/21/2012 70 Female 8/14/2012 Other Health Professional Us
Primary
Concomitant
Troponin Increased Other Serious 5/2012 Male 8/30/2012 Physician Nz
Primary
Concomitant
Presyncope Other Serious 8/10/2012 81 Male 176 lb 9/13/2012 Other Health Professional Gb
Primary
Concomitant
Pulmonary Congestion Hospitalization 5/2012 85 Female 9/21/2012 Physician Us
Primary
Concomitant
Coronary Artery Disease Other Serious 55 Male 9/19/2012 Physician Us
Primary
Concomitant

Drug Data