Nplate combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Therapeutic Response Decreased Hospitalization 10/22/2008 Female 1/12/2009 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious Male 2/10/2009 Consumer United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 73 Male 2/20/2009 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2009 Male 3/10/2009 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral Hospitalization 9/29/2008 Male 3/26/2009 Physician United States
Primary
Concomitant
Oedema Peripheral Hospitalization 9/29/2008 Male 4/1/2009 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious Male 210 lb 4/3/2009 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 10/22/2008 Female 4/14/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 10/20/2008 Male 205 lb 6/5/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 10/20/2008 Male 205 lb 6/9/2009 Physician United States
Primary
Concomitant
Thrombosis Other Serious 5/8/2009 Male 210 lb 6/18/2009 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/20/2008 Male 205 lb 6/19/2009 Physician United States
Primary
Concomitant
Thrombosis Other Serious 5/8/2009 Male 210 lb 7/21/2009 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 10/22/2008 Female 142 lb 9/22/2009 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious 7/21/2009 Female 225 lb 9/29/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 5/1/2009 Female 191 lb 10/5/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 5/1/2009 Female 191 lb 10/14/2009 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 10/20/2008 Male 205 lb 10/27/2009 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2009 Male 210 lb 11/5/2009 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2009 Male 210 lb 12/17/2009 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2009 Male 210 lb 2/17/2010 Physician United States
Primary
Concomitant
Fall Hospitalization 12/27/2009 79 Female 201 lb 2/19/2010 Physician Sweden
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2009 Male 210 lb 2/23/2010 Physician United States
Primary
Concomitant
Von Willebrand's Factor Antigen Increased Other Serious 12/23/2009 Female 119 lb 2/26/2010 Physician Hungary
Primary
Concomitant
Von Willebrand's Factor Antigen Increased Other Serious 12/23/2009 Female 119 lb 3/10/2010 Physician Hungary
Primary
Concomitant
Idiopathic Thrombocytopenic Purpura Hospitalization Female 151 lb 3/11/2010 Physician United States
Primary
Concomitant
Von Willebrand's Factor Antigen Increased Other Serious 12/23/2009 Female 119 lb 3/31/2010 Physician Hungary
Primary
Concomitant
Therapeutic Response Decreased Other Serious 11/27/2009 71 Female 4/9/2010 Physician United States
Primary
Concomitant
Von Willebrand's Factor Antigen Increased Other Serious 12/23/2009 56 Female 119 lb 4/27/2010 Physician Hungary
Primary
Concomitant
Thrombosis Other Serious 5/8/2009 74 Male 210 lb 4/29/2010 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 2/9/2009 70 Female 149 lb 5/6/2010 Physician United States
Primary
Concomitant
Von Willebrand's Factor Antigen Increased Other Serious 10/1/2009 56 Female 119 lb 5/19/2010 Physician Hungary
Primary
Concomitant
Platelet Count Decreased Other Serious 9/9/2009 76 Male 163 lb 5/25/2010 Physician Germany
Primary
Concomitant
Thrombocytopenia Other Serious 5/1/2009 50 Male 170 lb 6/2/2010 Other Health Professional United States
Primary
Concomitant
Platelet Count Decreased Other Serious 9/9/2009 76 Male 163 lb 6/3/2010 Physician Germany
Primary
Concomitant
Platelet Count Increased Other Serious 5/11/2010 63 Male 228 lb 6/4/2010 Other Health Professional United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/26/2009 43 Female 220 lb 6/8/2010 Physician United States
Primary
Concomitant
Telangiectasia Other Serious 3/23/2010 72 Male 157 lb 7/12/2010 Physician United States
Primary
Concomitant
Arterial Thrombosis Limb Other Serious 6/4/2010 83 Male 151 lb 8/4/2010 Physician United States
Primary
Concomitant
Thrombosis Other Serious 1/1/2009 64 Male 8/26/2010 Physician United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/26/2009 43 Female 220 lb 8/27/2010 Physician United States
Primary
Concomitant
Hypoaesthesia Male 179 lb 8/30/2010 Other Health Professional United States
Primary
Concomitant
Thrombosis Other Serious 7/2/2009 64 Male 9/2/2010 Physician
Primary
Concomitant
Thrombocytopenia Other Serious 9/1/2009 67 Male 145 lb 9/28/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/1/2010 10/18/2010 Physician United States
Primary
Concomitant
Death Death 10/25/2010 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 9/1/2010 10/25/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/25/2010 11/3/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Chronic Other Serious 1/1/2010 11/3/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Chronic Other Serious 1/1/2010 11/15/2010 Other Health Professional United States
Primary
Concomitant
Procedural Pain Other Serious 7/22/2009 11/18/2010 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 9/1/2010 11/19/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2010 11/23/2010 Physician United States
Primary
Concomitant
Traumatic Haematoma Other Serious 5/1/2010 11/28/2010 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 6/25/2010 11/29/2010 Other Health Professional United States
Primary
Concomitant
Drug Ineffective Other Serious 6/16/2010 11/30/2010 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/3/2010 12/7/2010 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 9/1/2010 12/7/2010 Other Health Professional United States
Primary
Concomitant
Platelet Count Increased Other Serious 12/9/2010 Physician Belgium
Primary
Concomitant
Pulmonary Embolism Other Serious 1/1/2009 12/14/2010 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/3/2010 12/15/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 7/13/2010 12/16/2010 Physician United States
Primary
Concomitant
Diabetes Mellitus Other Serious 9/23/2009 12/17/2010 Other Health Professional United States
Primary
Concomitant
Death Death 12/20/2010 Physician United States
Primary
Concomitant
Visual Field Defect Other Serious 7/3/2010 12/29/2010 Physician United States
Primary
Concomitant
Angiogram Other Serious 5/1/2010 1/13/2011 Other Health Professional United States
Primary
Concomitant
Haematuria Hospitalization 5/1/2009 1/21/2011 Physician United States
Primary
Concomitant
Seroma Other Serious 81 Male 167 lb 1/25/2011 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 6/16/2010 86 Female 209 lb 1/28/2011 Other Health Professional United States
Primary
Concomitant
Myalgia Other Serious 1/1/2010 74 Male 247 lb 1/28/2011 Physician United States
Primary
Concomitant
Anti-hbc Igg Antibody Positive Other Serious 5/1/2009 50 Male 170 lb 1/28/2011 Other Health Professional United States
Primary
Concomitant
Drug Ineffective Other Serious 6/16/2010 86 Female 209 lb 1/31/2011 Other Health Professional United States
Primary
Concomitant
Mitral Valve Incompetence Hospitalization 1/26/2009 43 Female 220 lb 2/3/2011 Physician United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 1/26/2009 43 Female 220 lb 2/8/2011 Physician United States
Primary
Concomitant
Diabetes Mellitus Other Serious 9/23/2009 72 Male 194 lb 2/16/2011 Other Health Professional United States
Primary
Concomitant
Idiopathic Thrombocytopenic Purpura Death 6/16/2010 86 Female 209 lb 2/18/2011 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/26/2009 43 Female 220 lb 2/21/2011 Physician United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 9/1/2010 69 Male 187 lb 2/24/2011 Other Health Professional United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 9/1/2010 69 Male 187 lb 3/4/2011 Physician United States
Primary
Concomitant
Diarrhoea Death 3/1/2010 94 Male 3/11/2011 Physician United States
Primary
Concomitant
Fluid Overload Hospitalization 1/26/2009 43 Female 220 lb 3/11/2011 Physician United States
Primary
Concomitant
Sepsis Death 2/24/2011 81 Female 171 lb 3/12/2011 Consumer United States
Primary
Concomitant
Platelet Count Increased Other Serious Female 165 lb 3/15/2011 Pharmacist United States
Primary
Concomitant
Hypokalaemia Death 3/1/2010 94 Male 3/21/2011 Physician United States
Primary
Concomitant
Post Procedural Complication Hospitalization 2/24/2011 81 Female 171 lb 3/22/2011 Consumer United States
Primary
Concomitant
Appendicitis Perforated Hospitalization 1/28/2011 49 Male 3/23/2011 Physician United States
Primary
Concomitant
Chest Pain Hospitalization 2/13/2011 80 Male 195 lb 3/28/2011 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 2/13/2011 80 Male 195 lb 4/1/2011 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral Other Serious 6/16/2010 68 Male 214 lb 4/7/2011 Physician United States
Primary
Concomitant
Hypersomnia Other Serious 12/1/2010 45 Male 211 lb 4/27/2011 Other Health Professional United States
Primary
Concomitant
Urticaria Other Serious 12/1/2010 45 Male 211 lb 5/4/2011 Other Health Professional United States
Primary
Concomitant
Embolism Other Serious 7/13/2010 62 Male 179 lb 5/5/2011 Physician United States
Primary
Concomitant
Abdominal Pain Other Serious 1/10/2011 76 Female 5/6/2011 Physician United States
Primary
Concomitant
Sudden Cardiac Death Other Serious 1/1/2009 56 Male 331 lb 5/9/2011 Pharmacist United States
Primary
Concomitant
Venous Thrombosis Limb Death 1/1/2009 56 Male 331 lb 5/10/2011 Pharmacist United States
Primary
Concomitant
Mental Status Changes Hospitalization 12/1/2010 45 Male 211 lb 5/18/2011 Other Health Professional United States
Primary
Concomitant
Death Death 6/4/2010 83 Male 151 lb 5/18/2011 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious 3/1/2011 72 Female 5/19/2011 Physician United States
Primary
Concomitant
Arterial Occlusive Disease Death 6/4/2010 83 Male 151 lb 5/27/2011 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious 3/1/2011 72 Female 6/3/2011 Other Health Professional United States
Primary
Concomitant
Abdominal Pain Other Serious 1/10/2011 76 Female 6/7/2011 Physician United States
Primary
Concomitant
Venous Thrombosis Limb Other Serious 1/1/2009 56 Male 331 lb 6/7/2011 Physician United States
Primary
Concomitant
Myeloproliferative Disorder Other Serious 12/16/2010 66 Male 198 lb 6/10/2011 Physician Sweden
Primary
Concomitant
Oedema Peripheral Other Serious Male 187 lb 6/14/2011 Physician United States
Primary
Concomitant
Sudden Cardiac Death Death 1/1/2009 56 Male 331 lb 6/15/2011 Pharmacist United States
Primary
Concomitant
Platelet Count Decreased Other Serious 4/20/2011 71 Male 234 lb 6/17/2011 Consumer United States
Primary
Concomitant
Myalgia Other Serious 1/1/2010 74 Male 247 lb 7/20/2011 Physician United States
Primary
Concomitant
Thrombosis Other Serious 6/25/2010 69 Female 7/26/2011 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious 7/25/2011 73 Male 7/28/2011 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 6/16/2010 86 Female 209 lb 8/1/2011 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 6/16/2010 86 Female 209 lb 8/3/2011 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious 7/25/2011 73 Male 198 lb 8/4/2011 Physician United States
Primary
Concomitant
Aphasia Other Serious 6/24/2011 84 Male 152 lb 8/12/2011 Physician United Kingdom
Primary
Concomitant
Atherectomy Death 5/1/2010 81 Male 9/6/2011 Other Health Professional United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 6/24/2011 84 Male 152 lb 9/8/2011 Physician United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 5/1/2010 81 Male 9/9/2011 Other Health Professional United States
Primary
Concomitant
Death Other Serious 5/1/2010 81 Male 9/13/2011 Physician United States
Primary
Concomitant
Weight Decreased Disability Male 260 lb 9/14/2011 Physician United States
Primary
Concomitant
Confusional State Other Serious Male 110 lb 9/20/2011 Physician United States
Primary
Concomitant
Petechiae Other Serious 1/1/2011 87 Male 238 lb 9/20/2011 Physician United States
Primary
Concomitant
Renal Failure Chronic Disability Male 110 lb 9/26/2011 Physician United States
Primary
Concomitant
Suture Related Complication Other Serious 5/1/2010 74 Male 9/29/2011 Physician United States
Primary
Concomitant
Drug Ineffective Hospitalization 5/1/2010 75 Male 148 lb 9/30/2011 Physician United States
Primary
Concomitant
Hepatic Encephalopathy Other Serious 12/30/2009 77 Female 184 lb 10/6/2011 Physician United States
Primary
Concomitant
Hepatic Encephalopathy Death 12/30/2009 77 Female 184 lb 10/6/2011 Pharmacist United States
Primary
Concomitant
Skin Haemorrhage Other Serious 5/1/2010 74 Male 10/6/2011 Physician United States
Primary
Concomitant
Death Other Serious 12/30/2009 77 Female 184 lb 10/7/2011 Physician United States
Primary
Concomitant
Oedema Peripheral Death 3/23/2010 72 Male 157 lb 10/11/2011 Physician United States
Primary
Concomitant
Haemorrhage Hospitalization 8/22/2011 83 Male 172 lb 10/17/2011 Pharmacist United States
Primary
Concomitant
Contusion Other Serious Male 10/25/2011 Physician United States
Primary
Concomitant
Nausea Other Serious 1/10/2011 76 Female 10/26/2011 Physician United States
Primary
Concomitant
Right Ventricular Dysfunction Death 8/22/2011 83 Male 172 lb 10/31/2011 Physician United States
Primary
Concomitant
Aortic Valve Disease Other Serious 10/31/2011 72 Male 11/7/2011 Consumer United States
Primary
Concomitant
Stasis Dermatitis Other Serious 1/1/2011 88 Male 238 lb 11/8/2011 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious 11/1/2011 69 Male 205 lb 11/18/2011 Consumer United States
Primary
Concomitant
Haemorrhage Death 8/22/2011 83 Male 172 lb 11/18/2011 Pharmacist United States
Primary
Concomitant
Petechiae Other Serious 1/1/2011 88 Male 238 lb 11/21/2011 Physician United States
Primary
Concomitant
Decreased Appetite Hospitalization 9/1/2011 68 Female 195 lb 11/23/2011 Physician United States
Primary
Concomitant
In-stent Coronary Artery Restenosis Hospitalization 8/10/2011 52 Male 226 lb 12/20/2011 Physician United States
Primary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 1/3/2012 Female 3/2/2012 Physician United States
Primary
Concomitant
Tinnitus 11/1/2011 72 Male 3/2/2012 Consumer United States
Primary
Concomitant
Leukocytosis 10/13/2010 52 Female 190 lb 3/2/2012 Other Health Professional United States
Primary
Concomitant
Platelet Count Decreased Other Serious Male 214 lb 3/19/2012 Consumer United States
Primary
Concomitant
Dizziness Other Serious Male 214 lb 3/21/2012 Other Health Professional United States
Primary
Concomitant
Dizziness Other Serious 3/1/2012 78 Male 216 lb 4/11/2012 Other Health Professional United States
Primary
Concomitant
Diverticulitis Other Serious Male 4/25/2012 Physician United States
Primary
Concomitant
Contusion Other Serious 3/1/2011 81 Male 5/3/2012 Physician United States
Primary
Concomitant
Intestinal Ischaemia Death 1/3/2012 73 Female 181 lb 5/14/2012 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/1/2012 78 Male 214 lb 5/18/2012 Physician United States
Primary
Concomitant
Fall Other Serious 11/1/2011 55 Male 5/23/2012 Physician United States
Primary
Concomitant

Drug Data