Paracetamol combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Brain Oedema Life Threatening 11/18/2005 63 Male 198 lb 1/3/2006 Physician Germany
Primary
Concomitant
Aortic Aneurysm Rupture Death 11/21/2003 Male 1/4/2006 France
Primary
Concomitant
Ventricular Fibrillation Life Threatening 12/13/2005 56 Male 176 lb 1/4/2006 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/13/2005 56 Male 176 lb 1/12/2006 Netherlands
Primary
Secondary
Concomitant
Abdominal Abscess Hospitalization 11/8/2004 Female 148 lb 1/25/2006 Netherlands
Primary
Concomitant
Rales Life Threatening 11/11/2005 85 Female 1/23/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Peripheral Embolism Other Serious 12/15/2004 Female 1/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Brain Oedema Life Threatening 11/18/2005 63 Male 198 lb 1/30/2006 Physician Germany
Primary
Concomitant
Neutropenia Hospitalization 11/20/2005 70 Female 1/25/2006 Switzerland
Primary
Secondary
Concomitant
Retroperitoneal Haematoma Required Intervention 12/1/2005 81 Male 190 lb 1/18/2006 Physician United States
Primary
Secondary
Concomitant
Aortic Dissection Death 4/5/2005 Male 2/1/2006 Consumer United Kingdom
Primary
Secondary
Aortic Dissection Death 4/5/2005 Male 2/1/2006 Consumer United Kingdom
Primary
Secondary
Restlessness Hospitalization 1/10/2006 78 Male 198 lb 2/8/2006
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 11/1/2004 61 Female 12/21/2005 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious Female 154 lb 3/16/2006 Physician Ireland
Primary
Concomitant
Interacting
Pulmonary Embolism Life Threatening 2/21/2006 74 Female 168 lb 4/12/2006 Physician Israel
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 50 Male 176 lb 4/5/2006 Physician Spain
Primary
Concomitant
Nervous System Disorder Hospitalization 3/14/2006 77 Female 4/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pleurisy Hospitalization 3/12/2006 68 Male 187 lb 5/5/2006 United Kingdom
Primary
Secondary
Concomitant
Skin Disorder Death 3/1/2006 42 Male 4/27/2006 Physician United Kingdom
Primary
Concomitant
Cardiac Failure Hospitalization 5/15/2006 Female 5/18/2006 Physician Australia
Primary
Concomitant
Oesophagitis Hospitalization 3/1/2006 61 Male 5/19/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 5/15/2006 Female 5/22/2006 Physician Australia
Primary
Concomitant
Pleurisy Hospitalization 3/12/2006 68 Male 187 lb 5/17/2006 United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 55 Male 5/26/2006 Consumer United Kingdom
Primary
Concomitant
Somnolence Other Serious 55 Male 6/1/2006 Consumer United Kingdom
Primary
Concomitant
Hepatic Function Abnormal Other Serious 2/21/2005 68 Male 154 lb 5/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Somnolence Other Serious 55 Male 6/9/2006 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 10/30/2004 55 Male 254 lb 6/12/2006 Physician United Kingdom
Primary
Concomitant
Urinary Retention Hospitalization 11/19/2005 78 Male 196 lb 6/13/2006 United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 55 Male 6/21/2006 Physician United Kingdom
Primary
Concomitant
Cardiac Failure Hospitalization 5/15/2006 Female 7/5/2006 Physician Australia
Primary
Concomitant
Coronary Artery Thrombosis Death 4/4/2006 Male 185 lb 7/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Granulocytopenia Required Intervention 4/19/2006 62 Male 180 lb 6/21/2006 United States
Primary
Concomitant
Convulsion Other Serious 7/3/2006 77 Male 8/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/10/2005 85 Female 8/28/2006 United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/25/2006 79 Female 8/29/2006 Denmark
Primary
Secondary
Concomitant
Vasculitis Other Serious 11/15/2005 Female 111 lb 9/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 9/8/2006 Other Health Professional Sweden
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 9/8/2006 Other Health Professional Sweden
Primary
Concomitant
Cellulitis Hospitalization 8/21/2006 76 Female 209 lb 9/6/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/13/2006 59 Male 157 lb 9/13/2006 Netherlands
Primary
Concomitant
Cellulitis Hospitalization 8/21/2006 76 Female 209 lb 9/14/2006
Primary
Secondary
Concomitant
Obstruction Other Serious 6/28/2006 Female 205 lb 9/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Coronary Artery Thrombosis Hospitalization 8/21/2006 57 Male 176 lb 9/20/2006 United States
Primary
Secondary
Concomitant
Delirium Hospitalization 66 Male 9/26/2006 Physician Switzerland
Primary
Concomitant
Urinary Tract Infection Other Serious 6/28/2006 64 Female 143 lb 9/27/2006 Physician Germany
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Cerebrovascular Accident Hospitalization 38 Male 1/4/2007 United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/13/2006 59 Male 157 lb 1/16/2007 Netherlands
Primary
Concomitant
Respiratory Disorder Other Serious 79 Male 1/16/2007 Physician Canada
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Malaise Hospitalization 1/10/2006 63 Female 192 lb 1/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Mouth Injury Other Serious 11/22/2006 Male 143 lb 1/19/2007 Physician United Kingdom
Primary
Concomitant
Coronary Artery Thrombosis Death 4/4/2006 Male 185 lb 1/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Immobile Hospitalization 10/26/2006 77 Female 1/18/2007 Other Health Professional United Kingdom
Primary
Concomitant
Fatigue Hospitalization 10/17/2006 47 Female 1/25/2007 Physician Sweden
Primary
Secondary
Concomitant
Hypotension Hospitalization 1/26/2007 81 Female 2/7/2007
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 7/5/2006 152 lb 2/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tachycardia Other Serious 7/11/2006 80 Female 2/19/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Hypotension Hospitalization 1/26/2007 81 Female 2/20/2007
Primary
Concomitant
Dystonia Hospitalization 1/3/2007 68 Female 4/3/2007 United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 12/1/2006 60 Male 4/11/2007 Other Health Professional France
Primary
Secondary
Concomitant
Femoral Neck Fracture Hospitalization 2/4/2007 76 Male 4/12/2007 Other Health Professional Sweden
Primary
Concomitant
Dystonia Hospitalization 1/3/2007 68 Female 4/5/2007 United Kingdom
Primary
Secondary
Concomitant
Skin Test Positive Hospitalization 12/8/2006 83 Female 4/6/2007 France
Primary
Concomitant
Dyspnoea Hospitalization 3/7/2007 51 Female 265 lb 4/18/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Fall Other Serious 11/22/2006 Male 143 lb 4/19/2007 Physician United Kingdom
Primary
Concomitant
Malaise Hospitalization 2/16/2007 74 Female 187 lb 4/23/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Haemorrhagic Stroke Hospitalization 3/27/2007 74 4/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Wound Secretion Hospitalization 10/25/2006 67 Female 4/30/2007 Other Health Professional Australia
Primary
Concomitant
Rash Hospitalization 4/9/2004 65 Female 5/3/2007 Consumer United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 5/4/2007 Other Health Professional Sweden
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 12/5/2006 Female 269 lb 5/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Chronic Other Serious 5/1/2006 73 Male 5/10/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 12/22/2005 72 Female 99 lb 5/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Disorder Other Serious 9/1/2005 79 Male 5/14/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 45 Male 201 lb 5/14/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 4/1/2006 59 Male 157 lb 6/4/2007 Netherlands
Primary
Concomitant
Rhabdomyolysis Hospitalization 81 Male 6/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 81 Male 6/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Musculoskeletal Chest Pain Hospitalization 12/5/2005 Female 269 lb 6/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 81 Male 6/19/2007 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/1/2006 59 Male 157 lb 6/29/2007 Netherlands
Primary
Concomitant
Overdose Disability 80 Female 6/29/2007 Physician United Kingdom
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 5/21/2007 Female 7/9/2007 United Kingdom
Primary
Concomitant
Cellulitis Hospitalization 8/21/2006 76 Female 209 lb 7/11/2007
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2007 Male 7/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hospitalisation Hospitalization Female 7/13/2007 Canada
Primary
Concomitant
Pyrexia Hospitalization 7/16/2006 Male 293 lb 7/16/2007 United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 6/8/2006 Female 157 lb 7/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Gastrointestinal Stromal Tumour Hospitalization 62 Female 7/31/2007 Physician Finland
Primary
Secondary
Concomitant
Vasculitic Rash Other Serious 6/24/2007 64 Female 149 lb 7/31/2007 United Kingdom
Primary
Concomitant
Suicidal Ideation Hospitalization 11/15/2005 Female 106 lb 8/10/2007 Physician United Kingdom
Primary
Concomitant
Peripheral Arterial Occlusive Disease Life Threatening 5/13/2007 71 Male 8/15/2007 Physician Germany
Primary
Concomitant
Dyspnoea Hospitalization 8/5/2007 35 Female 294 lb 8/17/2007 Consumer United Kingdom
Primary
Concomitant
Peripheral Arterial Occlusive Disease Life Threatening 5/13/2007 71 Male 8/20/2007 Physician Germany
Primary
Concomitant
Pancreatitis Hospitalization 11/21/2006 Male 8/21/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Ileus Hospitalization Female 8/22/2007 Pharmacist United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 4/18/2007 Female 168 lb 8/24/2007 Physician Germany
Primary
Concomitant
Urinary Tract Infection Enterococcal Hospitalization 4/19/2007 Female 154 lb 8/24/2007 Physician Germany
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 8/27/2007 Other Health Professional Sweden
Primary
Concomitant
Chest Pain Hospitalization 7/7/2007 Female 155 lb 8/29/2007 Canada
Primary
Concomitant
Rib Fracture Hospitalization 7/18/2007 76 Female 238 lb 8/31/2007 Consumer United Kingdom
Primary
Concomitant
Fall Hospitalization 7/18/2007 76 Female 238 lb 9/6/2007 Consumer United Kingdom
Primary
Concomitant
Gait Disturbance Other Serious 7/27/2007 83 128 lb 9/6/2007 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Life Threatening 8/9/2007 76 Female 152 lb 9/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Malaise Other Serious 6/12/2007 40 Male 9/10/2007 United Kingdom
Primary
Secondary
Concomitant
Neutropenic Colitis Death 8/15/2007 65 Male 9/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Malaise Other Serious 1/1/2007 40 Male 9/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Other Serious 1/1/2007 73 Female 9/18/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Fall Hospitalization 7/18/2007 76 Female 238 lb 9/18/2007 Physician United Kingdom
Primary
Concomitant
Malaise Other Serious 1/1/2007 40 Male 9/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nightmare Other Serious 1/1/2007 77 Male 9/19/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Life Threatening 1/1/2007 73 Female 9/24/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Life Threatening 1/1/2007 73 Female 9/19/2007 United Kingdom
Primary
Concomitant
Neutropenic Colitis Death 8/15/2007 65 Male 194 lb 9/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 7/3/2007 67 Female 377 lb 10/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Ileus Hospitalization Female 10/3/2007 Pharmacist United Kingdom
Primary
Concomitant
Interacting
Malaise Other Serious 1/1/2007 40 Male 10/4/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vaginal Haemorrhage Other Serious 57 Female 148 lb 10/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Coronary Artery Disease Hospitalization 5/31/2007 65 Male 9/27/2007 Other Health Professional Netherlands
Primary
Concomitant
Hypotension Life Threatening 7/18/2007 47 Female 126 lb 10/5/2007 Physician United States
Primary
Secondary
Concomitant
Urticaria Other Serious 9/14/2007 68 Male 10/10/2007 Consumer United Kingdom
Primary
Concomitant
Fall Hospitalization 7/18/2007 76 Female 238 lb 10/12/2007 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/15/2007 65 Male 194 lb 10/16/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 8/17/2007 75 Female 194 lb 10/16/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/15/2007 Male 132 lb 10/17/2007 Physician United Kingdom
Primary
Concomitant
Haemoglobin Decreased Life Threatening 12/1/2005 58 Male 10/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Septic Shock Hospitalization 8/15/2007 65 Male 194 lb 10/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Life Threatening 7/18/2007 47 Female 126 lb 10/26/2007 Physician United States
Primary
Secondary
Concomitant
Nausea Life Threatening 7/18/2007 47 Female 11/6/2007 United States
Primary
Secondary
Concomitant
Tremor Other Serious 9/14/2007 75 Male 146 lb 11/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Palpitations Other Serious 2/4/2006 64 Female 11/8/2007 Physician United Kingdom
Primary
Concomitant
Hepatitis Other Serious 8/3/2007 64 Male 11/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Life Threatening 9/14/2007 75 Male 146 lb 11/15/2007 Pharmacist United Kingdom
Primary
Concomitant
Interacting
Atrial Fibrillation Hospitalization 8/17/2007 75 Female 194 lb 11/16/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 11/20/2006 85 Female 11/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Renal Failure Acute Other Serious 8/9/2007 Male 165 lb 11/20/2007 Physician Australia
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 5/19/2006 73 Male 280 lb 11/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 10/2/2007 Female 115 lb 11/21/2007 Other Health Professional United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 11/20/2006 85 Female 11/22/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 10/14/2007 84 Female 11/20/2007 United Kingdom
Primary
Concomitant
Tremor Life Threatening 9/14/2007 75 Male 11/16/2007 United Kingdom
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Other Serious 5/6/2007 Male 154 lb 12/3/2007 Other Health Professional United Kingdom
Primary
Concomitant

Drug Data