Simvastatin combined with Velcade

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Mucosal Inflammation Hospitalization 12/5/2005 61 Female 4/3/2006 Physician Netherlands
Primary
Secondary
Concomitant
Dysarthria Other Serious 4/1/2005 70 Male 245 lb 5/18/2006 Physician United States
Primary
Concomitant
Urticaria Other Serious 1/27/2006 59 Female 181 lb 5/22/2006 Physician United Kingdom
Primary
Concomitant
Oral Intake Reduced Hospitalization 12/5/2005 61 Female 6/16/2006 Physician Netherlands
Primary
Secondary
Concomitant
Orthostatic Hypotension 6/1/2003 75 Male 5/24/2006 Consumer United States
Primary
Concomitant
Viral Infection Other Serious 6/16/2006 66 Male 7/12/2006 Physician Australia
Primary
Secondary
Concomitant
Syncope Other Serious 11/24/2005 64 Male 159 lb 7/5/2006 Physician Poland
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/16/2006 66 Male 7/19/2006 Physician Australia
Primary
Secondary
Concomitant
Pancreatitis Other Serious 5/29/2006 69 Male 195 lb 8/29/2006 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 5/29/2006 69 Male 195 lb 10/5/2006 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 5/29/2006 69 Male 195 lb 10/20/2006 Physician United States
Primary
Secondary
Concomitant
Spinal Osteoarthritis Other Serious 4/1/2005 70 Male 245 lb 11/6/2006 Physician United States
Primary
Concomitant
Polyneuropathy Hospitalization 67 Male 168 lb 11/7/2006 Physician France
Primary
Concomitant
Oesophagitis Hospitalization 10/30/2006 Male 11/17/2006 Physician Belgium
Primary
Concomitant
Oesophagitis Hospitalization 10/1/2006 68 Male 150 lb 11/28/2006 Physician Belgium
Primary
Concomitant
Pyrexia Life Threatening 11/10/2006 60 Female 212 lb 11/28/2006 Physician Australia
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 11/10/2006 60 Female 212 lb 1/3/2007 Physician Australia
Primary
Secondary
Concomitant
Hepatic Cancer Metastatic Other Serious 3/7/2007 66 Male 3/29/2007 Physician Australia
Primary
Concomitant
Metastases To Liver Other Serious 3/7/2007 66 Male 4/19/2007 Physician Australia
Primary
Concomitant
Hepatic Cancer Metastatic Other Serious 3/7/2007 66 Male 5/22/2007 Physician Australia
Primary
Concomitant
Thrombocytopenia Hospitalization 11/10/2006 60 Female 212 lb 5/24/2007 Physician Australia
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 2/19/2007 69 Female 6/15/2007 Physician Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 2/19/2007 69 Female 104 lb 7/9/2007 Physician Japan
Primary
Concomitant
Colon Cancer Other Serious 3/13/2007 66 Male 7/12/2007 Physician Australia
Primary
Concomitant
Metastases To Liver Other Serious 3/13/2007 66 Male 8/16/2007 Physician Australia
Primary
Concomitant
Respiratory Failure Other Serious 6/16/2006 66 Male 9/25/2007 Physician Australia
Primary
Secondary
Concomitant
Tachycardia Other Serious 6/16/2006 66 Male 10/8/2007 Physician Australia
Primary
Secondary
Concomitant
Viral Myocarditis Death 10/22/2007 63 Male 203 lb 10/26/2007 Physician Netherlands
Primary
Secondary
Concomitant
Stomach Discomfort Hospitalization 7/30/2007 55 Male 181 lb 11/5/2007 Physician Japan
Primary
Secondary
Concomitant
Metastases To Liver Other Serious 3/13/2007 66 Male 11/8/2007 Physician Australia
Primary
Concomitant
Immunosuppression Hospitalization 7/30/2007 55 Male 181 lb 11/23/2007 Physician Japan
Primary
Secondary
Concomitant
Viral Myocarditis Death 10/22/2007 63 Male 203 lb 12/14/2007 Physician Netherlands
Primary
Secondary
Concomitant
Metastases To Liver Other Serious 3/13/2007 66 Male 12/27/2007 Physician Australia
Primary
Concomitant
Immune System Disorder Hospitalization 7/30/2007 55 Male 181 lb 1/4/2008 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/30/2007 55 Male 181 lb 2/27/2008 Physician Japan
Primary
Secondary
Concomitant
Cold Sweat Hospitalization 4/2/2008 64 Male 171 lb 4/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 6/26/2006 59 Female 240 lb 4/15/2008 Physician United States
Primary
Secondary
Concomitant
Drug Ineffective Death 12/1/2007 65 Male 101 lb 4/18/2008 Pharmacist United Kingdom
Primary
Concomitant
Hypotension Hospitalization 4/1/2008 57 Female 4/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 6/26/2006 59 Female 240 lb 4/25/2008 Physician United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 4/1/2008 57 Female 4/30/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 6/26/2006 59 Female 240 lb 5/13/2008 Physician United States
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 1/7/2008 51 Male 258 lb 6/12/2008 Pharmacist United Kingdom
Primary
Concomitant
Ventricular Fibrillation Hospitalization 6/19/2008 58 Male 126 lb 6/23/2008 Physician Portugal
Primary
Secondary
Concomitant
Tinnitus Other Serious 4/4/2008 47 Male 165 lb 6/26/2008 Physician Germany
Primary
Secondary
Concomitant
Hypotension Hospitalization 4/1/2008 57 Female 7/14/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 2/5/2007 69 Female 104 lb 7/18/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/18/2008 67 Female 109 lb 7/31/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Tinnitus Other Serious 4/4/2008 47 Male 165 lb 8/11/2008 Physician Germany
Primary
Secondary
Concomitant
Coronary Artery Disease Life Threatening 4/2/2008 64 Male 171 lb 8/12/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/13/2008 75 Male 155 lb 8/28/2008 Physician United States
Primary
Secondary
Concomitant
Radiation Pneumonitis Other Serious 7/1/2008 67 Male 215 lb 9/10/2008 Physician United States
Primary
Secondary
Concomitant
Radiation Pneumonitis Hospitalization 8/9/2008 Male 215 lb 9/17/2008 Physician United States
Primary
Secondary
Concomitant
Dysphagia Other Serious 9/19/2008 63 Female 110 lb 9/19/2008 Physician United States
Primary
Secondary
Concomitant
Nausea Other Serious 9/19/2008 63 Female 110 lb 9/23/2008 Physician United States
Primary
Secondary
Concomitant
Coronary Artery Disease Life Threatening 4/2/2008 64 Male 171 lb 9/22/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Radiation Pneumonitis Other Serious 8/9/2008 Male 215 lb 10/20/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/1/2008 67 Male 215 lb 10/15/2008 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 10/14/2008 63 Female 104 lb 10/27/2008 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 10/14/2008 63 Female 104 lb 10/22/2008 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 5/8/2008 Male 184 lb 11/12/2008 Physician United States
Primary
Secondary
Concomitant
Death Death Unknown 11/7/2008 Physician Brazil
Primary
Concomitant
Troponin Increased Life Threatening 6/11/2008 59 Male 174 lb 11/10/2008 Physician Germany
Primary
Secondary
Concomitant
Polyneuropathy Hospitalization 7/9/2007 72 Male 214 lb 11/14/2008 Physician Netherlands
Primary
Concomitant
Otitis Media Hospitalization 4/28/2007 71 Male 11/17/2008 Physician Netherlands
Primary
Concomitant
Death Death 10/2/2008 11/26/2008 Physician Brazil
Primary
Concomitant
Thrombocytopenia Life Threatening 6/11/2008 59 Male 174 lb 11/21/2008 Physician Germany
Primary
Secondary
Concomitant
Colonoscopy Death 10/2/2008 12/5/2008 Physician Brazil
Primary
Concomitant
Radiation Pneumonitis Other Serious 8/9/2008 Male 215 lb 12/23/2008 Physician United States
Primary
Secondary
Concomitant
Radiation Pneumonitis Other Serious 7/1/2008 67 Male 215 lb 12/22/2008 Physician United States
Primary
Secondary
Concomitant
Septic Shock Death 10/2/2008 12/23/2008 Physician Brazil
Primary
Concomitant
Radiation Pneumonitis Other Serious 7/1/2008 67 Male 215 lb 12/23/2008 Physician United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 12/10/2008 62 Male 116 lb 1/22/2009 Physician United States
Primary
Secondary
Concomitant
Urticaria Hospitalization Male 2/5/2009 Physician Germany
Primary
Concomitant
Oesophagitis Hospitalization 1/8/2009 63 Male 187 lb 2/26/2009 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 8/19/2008 52 Female 165 lb 2/27/2009 Physician United States
Primary
Secondary
Concomitant
Urinary Incontinence Life Threatening 2/19/2007 69 Female 104 lb 3/2/2009 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/28/2008 52 Female 165 lb 3/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tachyarrhythmia Life Threatening 10/11/2008 60 Male 176 lb 3/12/2009 Physician France
Primary
Concomitant
Unresponsive To Stimuli Other Serious 2/9/2009 88 Male 181 lb 3/17/2009 Physician United States
Primary
Secondary
Concomitant
Tachyarrhythmia Life Threatening 10/11/2008 60 Male 176 lb 3/16/2009 Physician France
Primary
Concomitant
Ventricular Fibrillation Death 6/19/2008 58 Male 3/25/2009 Portugal
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 1/8/2009 63 Male 187 lb 3/26/2009 Physician France
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 6/19/2008 58 Male 126 lb 3/27/2009 Physician Portugal
Primary
Secondary
Concomitant
Respiratory Arrest Death 4/2/2009 62 Male 282 lb 4/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 6/19/2008 58 Male 126 lb 4/9/2009 Physician Portugal
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 3/27/2009 Male 174 lb 4/24/2009 Physician United States
Primary
Secondary
Concomitant
Cardiac Arrest Death 4/2/2009 62 Male 282 lb 4/24/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 7/1/2008 67 Male 215 lb 4/24/2009 Physician United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 6/19/2008 58 Male 126 lb 4/27/2009 Physician Portugal
Primary
Secondary
Concomitant
Tinnitus Other Serious 4/4/2008 47 Male 165 lb 5/8/2009 Physician Germany
Primary
Secondary
Concomitant
Vision Blurred Other Serious 5/8/2008 Male 184 lb 6/10/2009 Physician United States
Primary
Secondary
Concomitant
Wheezing Other Serious 3/6/2009 57 Male 132 lb 6/19/2009 United Kingdom
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 5/19/2009 Male 7/9/2009 United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 5/26/2009 71 Male 231 lb 7/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Diabetes Mellitus Hospitalization 1/16/2009 60 Male 161 lb 7/17/2009 Physician France
Primary
Secondary
Concomitant
Acute Myocardial Infarction Death 4/2/2009 62 Male 282 lb 7/30/2009 Physician United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 5/19/2009 Male 8/4/2009 United States
Primary
Secondary
Concomitant
Diabetes Mellitus Hospitalization 1/16/2009 60 Male 161 lb 8/4/2009 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/10/2009 80 Female 148 lb 8/4/2009 Physician United States
Primary
Secondary
Concomitant
Weight Bearing Difficulty Hospitalization 8/3/2009 79 Male 151 lb 8/11/2009 Physician United States
Primary
Secondary
Concomitant
Sinusitis Hospitalization 4/28/2007 71 Male 8/26/2009 Physician Netherlands
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 1/1/2009 87 Female 133 lb 9/23/2009 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 8/20/2009 77 Male 165 lb 9/28/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/1/2009 68 Male 9/30/2009 Physician United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 1/8/2009 63 Male 187 lb 10/6/2009 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 2/1/2009 68 Male 10/14/2009 Physician United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 9/27/2009 58 Male 237 lb 11/11/2009 Physician United Kingdom
Primary
Concomitant
Vomiting Life Threatening 11/24/2008 56 Female 11/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 9/27/2009 58 Male 237 lb 11/24/2009 Physician United Kingdom
Primary
Concomitant
Aortic Stenosis Death 11/13/2009 1/19/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 11/24/2008 56 Female 1/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/20/2009 77 Male 165 lb 2/11/2010 Physician United States
Primary
Secondary
Concomitant
Tumour Pain Hospitalization 5/22/2009 74 Female 187 lb 3/1/2010 Physician Spain
Primary
Secondary
Concomitant
Renal Failure Hospitalization 4/27/2009 3/3/2010 Physician France
Primary
Concomitant
Tachyarrhythmia Hospitalization 10/11/2008 60 Male 176 lb 2/22/2010 Physician France
Primary
Concomitant
Tachyarrhythmia Hospitalization 10/11/2008 60 Male 176 lb 3/5/2010 Physician France
Primary
Concomitant
Walking Aid User Other Serious 5/1/2007 Male 219 lb 3/19/2010 United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 5/1/2007 Male 219 lb 3/31/2010 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 7/26/2009 63 Female 3/31/2010 Pharmacist United States
Primary
Concomitant
Pharyngeal Operation Other Serious 12/21/2009 79 Male 190 lb 4/2/2010 Other Health Professional United States
Primary
Concomitant
Sinus Tachycardia Hospitalization 3/18/2010 56 Male 4/7/2010 Physician United States
Primary
Secondary
Concomitant
Tachyarrhythmia Hospitalization 10/11/2008 60 Male 176 lb 4/8/2010 Physician France
Primary
Concomitant
Wound Infection Other Serious 5/1/2007 68 Male 219 lb 4/15/2010 United States
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 10/29/2009 77 Female 122 lb 4/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/10/2009 80 Female 148 lb 5/3/2010 Physician United States
Primary
Secondary
Concomitant
Vascular Insufficiency Other Serious 1/1/1995 57 Male 5/11/2010 United States
Primary
Secondary
Concomitant
Failure To Thrive Hospitalization 4/10/2010 73 Male 5/14/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/24/2009 69 Female 152 lb 5/21/2010 Pharmacist United States
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 8/1/2001 63 Male 6/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 6/15/2010 United States
Primary
Secondary
Concomitant
Ulcer Other Serious 1/1/2002 81 Male 6/15/2010 United States
Primary
Concomitant
Vaginal Ulceration Other Serious 2/1/2010 69 Female 6/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 8/1/2001 63 Male 6/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 10/29/2009 77 Female 122 lb 6/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 10/16/2009 67 Male 168 lb 7/6/2010 Physician Canada
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 7/7/2010 United States
Primary
Secondary
Concomitant
Acute Febrile Neutrophilic Dermatosis Hospitalization 6/17/2009 7/16/2010 Physician Australia
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 7/19/2010 United States
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 1/26/2010 48 Male 150 lb 7/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 6/1/2010 79 Female 125 lb 7/21/2010 Physician United States
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 7/7/2010 7/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Orthostatic Hypotension Hospitalization 7/1/2010 79 Female 125 lb 7/28/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/4/2010 7/29/2010 Physician Netherlands
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 1/26/2010 48 Male 150 lb 7/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 4/27/2009 8/5/2010 Physician France
Primary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 8/6/2010 United States
Primary
Secondary
Concomitant
Tachyarrhythmia Other Serious 10/11/2008 60 Male 176 lb 8/11/2010 Physician France
Primary
Concomitant
Pneumonia Bacterial Hospitalization 5/23/2010 77 Male 8/24/2010 Other Health Professional United States
Primary
Concomitant
Tachyarrhythmia Life Threatening 10/11/2008 60 Male 176 lb 8/19/2010 Physician France
Primary
Concomitant

Drug Data