Amitriptyline combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Schizophrenia Life Threatening 8/3/2005 Male 222 lb 3/31/2006 Physician United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Hospitalization 8/1/2007 Male 220 lb 11/13/2007 Consumer United States
Primary
Concomitant
Infected Skin Ulcer Hospitalization 8/8/2008 12/14/2008 Physician Brazil
Primary
Secondary
Concomitant
Renal Failure Hospitalization 4/30/2008 71 Female 200 lb 12/12/2008 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 12/24/2008 Consumer Brazil
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 9/11/2008 Male 223 lb 12/24/2008 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 2/9/2009 Consumer Brazil
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 1/1/2008 75 Male 213 lb 2/12/2009 Physician United Kingdom
Primary
Concomitant
Skin Burning Sensation Other Serious 66 Male 2/17/2009 Pharmacist United States
Primary
Concomitant
Skin Necrosis Other Serious 66 Male 2/18/2009 Pharmacist United States
Primary
Concomitant
Ototoxicity Hospitalization 10/10/2007 74 Female 146 lb 2/20/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Ototoxicity Hospitalization 10/10/2007 74 Female 146 lb 2/27/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/20/2009 64 Female 3/3/2009 Consumer United States
Primary
Concomitant
Tachycardia Hospitalization 2/2/2009 80 Female 3/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
Lower Limb Fracture Other Serious 6/1/2006 38 Female 3/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/1/2008 74 Male 154 lb 3/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Urinary Tract Infection 7/1/2008 Female 154 lb 3/14/2009 United States
Primary
Concomitant
Red Blood Cell Count Decreased Hospitalization 11/1/2008 74 Male 154 lb 3/10/2009 Physician Germany
Primary
Secondary
Concomitant
Liver Injury Hospitalization 9/12/2008 63 Female 3/18/2009 Other Health Professional France
Primary
Secondary
Concomitant
Gait Disturbance Hospitalization 11/14/2008 3/17/2009 Germany
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/1/2008 74 Male 154 lb 3/24/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Productive Cough Hospitalization 1/6/2009 Female 117 lb 3/24/2009 United Kingdom
Primary
Concomitant
Pitting Oedema Other Serious 1/1/2008 75 Male 3/30/2009 Other Health Professional United States
Primary
Concomitant
Confusional State Life Threatening 2/26/2009 49 Male 3/31/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Life Threatening 2/26/2009 49 Male 3/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Obesity Hospitalization 3/10/2009 Female 229 lb 5/27/2009 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2007 Male 174 lb 6/17/2009 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 4/6/2009 78 Female 6/19/2009 United Kingdom
Primary
Concomitant
Transaminases Increased Hospitalization 4/8/2009 Male 220 lb 6/30/2009 Other Health Professional Germany
Primary
Concomitant
Pancytopenia Hospitalization 9/1/2008 77 6/30/2009 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 6/3/2009 Female 7/8/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Life Threatening 6/8/2009 Female 7/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vertigo Hospitalization 2/14/2009 Male 185 lb 7/21/2009
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/9/2008 65 7/28/2009 Physician Germany
Primary
Secondary
Concomitant
Interacting
Unevaluable Event Hospitalization 71 Female 7/22/2009 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/9/2008 65 Female 7/31/2009 Physician Germany
Primary
Secondary
Concomitant
Skin Burning Sensation Other Serious 66 Male 8/7/2009 Pharmacist United States
Primary
Concomitant
Renal Failure Death 4/13/2009 Female 146 lb 8/11/2009 United Kingdom
Primary
Concomitant
Diabetic Neuropathy Other Serious 5/9/2006 49 Female 210 lb 8/13/2009 United States
Primary
Concomitant
Wheezing Hospitalization 9/28/2005 71 Female 8/11/2009 United States
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 10/3/2006 65 Male 213 lb 8/20/2009 Other Health Professional United States
Primary
Concomitant
Pulmonary Fibrosis Disability 4/15/2008 Male 201 lb 8/20/2009 United Kingdom
Primary
Concomitant
Paraesthesia 10/29/2008 Female 8/22/2009 United States
Primary
Concomitant
Pruritus 6/18/2009 Female 130 lb 8/22/2009 United States
Primary
Concomitant
Skin Burning Sensation 6/26/2009 Male 235 lb 8/23/2009 United States
Primary
Concomitant
Pruritus Generalised 7/1/2009 Male 232 lb 8/23/2009 United States
Primary
Concomitant
Hypoglycaemia Life Threatening 3/6/2006 81 Female 8/20/2009 United Kingdom
Primary
Concomitant
Flushing 6/1/2009 Female 8/29/2009 United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 7/12/2007 Female 137 lb 8/31/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 1/1/2007 54 Male 381 lb 9/3/2009 Lawyer United States
Primary
Concomitant
Renal Impairment Hospitalization 12/22/2008 84 Female 128 lb 9/8/2009 Consumer United Kingdom
Primary
Concomitant
Wheezing Hospitalization 9/28/2005 71 Female 9/8/2009 United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 12/7/2007 Female 137 lb 9/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Retention Hospitalization 9/10/2009 Male 250 lb 9/22/2009 Physician United Kingdom
Primary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 6/24/2002 46 Female 180 lb 9/23/2009 United States
Primary
Concomitant
Hyponatraemia Life Threatening 2/26/2009 49 Male 9/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pancytopenia Hospitalization 9/1/2008 77 10/1/2009 United Kingdom
Primary
Secondary
Concomitant
Vertigo Other Serious 2/19/2009 Male 185 lb 10/1/2009
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 12/7/2007 Female 137 lb 10/1/2009 Other Health Professional United Kingdom
Primary
Concomitant
Presyncope Other Serious 61 Female 230 lb 10/2/2009 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 4/1/2008 63 Female 165 lb 10/2/2009 Physician United States
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 10/3/2006 65 Male 213 lb 10/2/2009 Other Health Professional United States
Primary
Concomitant
Painful Defaecation Other Serious 8/18/2008 Female 176 lb 10/5/2009 Consumer Brazil
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/20/2004 46 Male 234 lb 10/5/2009 United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 10/3/2006 65 Male 213 lb 10/7/2009 Other Health Professional United States
Primary
Concomitant
Loss Of Consciousness Other Serious 7/1/2008 55 Female 174 lb 10/9/2009 Consumer United States
Primary
Concomitant
Loss Of Consciousness Other Serious 7/1/2008 55 Female 174 lb 10/14/2009 Consumer United States
Primary
Concomitant
Spinal Fracture Hospitalization 11/1/2008 Female 10/14/2009 United Kingdom
Primary
Concomitant
Vertigo Other Serious 2/19/2009 Male 185 lb 10/16/2009
Primary
Secondary
Concomitant
Staphylococcal Sepsis Death 6/1/2008 Male 205 lb 10/16/2009 United Kingdom
Primary
Concomitant
Ulcer Haemorrhage Other Serious 11/8/2008 75 Male 161 lb 10/19/2009 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 2/1/2009 61 Male 10/19/2009 Pharmacist Germany
Primary
Concomitant
Renal Impairment Other Serious 5/21/2009 59 Female 183 lb 10/27/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Acute Myocardial Infarction Death 6/2/2007 80 Female 10/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Skin Ulcer Life Threatening 2/4/2006 Female 10/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Arteriosclerosis Hospitalization 78 Female 10/23/2009 United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 12/8/2008 70 Male 10/23/2009 United Kingdom
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 8/25/2009 51 Male 225 lb 10/30/2009 Pharmacist United States
Primary
Secondary
Concomitant
Investigation Hospitalization 7/22/2009 75 Female 11/10/2009 Consumer Canada
Primary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 9/1/2009 62 Female 265 lb 11/13/2009 United Kingdom
Primary
Concomitant
Wound Infection Hospitalization 56 Male 325 lb 11/17/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 9/28/2005 70 Female 11/18/2009 United States
Primary
Concomitant
Hypotension Hospitalization 12/4/2008 Male 12/2/2009 Physician Netherlands
Primary
Secondary
Concomitant
Pain Other Serious Female 128 lb 12/3/2009 Brazil
Primary
Concomitant
Poor Peripheral Circulation Hospitalization 5/9/2007 Female 12/1/2009 Physician United States
Primary
Concomitant
Serotonin Syndrome Hospitalization 1/1/2006 71 Male 12/1/2009 Physician United Kingdom
Primary
Concomitant
Urinary Incontinence Hospitalization 1/1/2007 54 Female 12/4/2009 Consumer Brazil
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2007 Male 174 lb 12/1/2009 Consumer United States
Primary
Concomitant
Thrombocytopenia Life Threatening 9/18/2009 Female 154 lb 12/8/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/13/2007 61 Male 214 lb 12/9/2009 Lawyer United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 62 Female 12/9/2009 Lawyer United States
Primary
Secondary
Concomitant
Death Death 12/10/2009 Female 139 lb 12/15/2009 Other Health Professional United States
Primary
Concomitant
Pulmonary Hypertension Death Female 139 lb 12/18/2009 Physician United States
Primary
Concomitant
Neutropenic Sepsis Life Threatening 3/9/2009 66 Female 115 lb 12/16/2009 Austria
Primary
Secondary
Concomitant
Wrist Fracture Hospitalization 1/1/2008 51 Female 12/29/2009 Other Health Professional United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 11/16/2009 74 Female 163 lb 12/30/2009 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 70 Female 12/23/2009 Physician Israel
Primary
Concomitant
Aortic Stenosis Death 11/13/2009 1/19/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Life Threatening 5/12/2008 71 Female 1/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Skin Ulcer Other Serious 9/1/2006 79 Male 152 lb 1/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pruritus Other Serious 1/20/2010 Female 114 lb 2/17/2010 Physician United States
Primary
Concomitant
Pruritus Other Serious 1/20/2010 Female 114 lb 3/8/2010 Physician United States
Primary
Concomitant
Death Death 11/5/2009 60 Female 4/1/2010 Pharmacist United States
Primary
Concomitant
Dizziness Life Threatening 79 Female 126 lb 4/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Rash Hospitalization 1/1/2010 Female 4/21/2010 Consumer United Kingdom
Primary
Concomitant
Death Death Female 252 lb 4/22/2010 Other Health Professional United States
Primary
Concomitant
Rheumatoid Arthritis Death 1/1/2007 67 Female 4/26/2010 United Kingdom
Primary
Concomitant
Vision Blurred Other Serious 4/19/2010 41 Female 4/28/2010 Other Health Professional Netherlands
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 1/1/2009 51 Male 5/16/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 71 Female 79 lb 5/26/2010 Consumer United States
Primary
Concomitant
Stress Other Serious 4/27/2010 83 Female 108 lb 6/4/2010 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 29 Female 143 lb 6/4/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vascular Insufficiency Other Serious 10/1/2007 77 Female 6/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 6/7/2010 Other Health Professional Israel
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization Female 6/10/2010 Other Health Professional Israel
Primary
Secondary
Toxic Epidermal Necrolysis Hospitalization Female 6/16/2010 Physician France
Primary
Secondary
Skin Ulcer Hospitalization Male 209 lb 6/17/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 70 Female 6/18/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization Female 6/21/2010 Physician France
Primary
Secondary
Toxic Epidermal Necrolysis Hospitalization 70 Female 6/22/2010 Other Health Professional France
Primary
Secondary
Concomitant
Haemorrhage Intracranial Hospitalization 48 Male 6/22/2010 Physician United States
Primary
Concomitant
Paraesthesia Other Serious 6/11/2010 41 Female 6/23/2010 Other Health Professional Netherlands
Primary
Concomitant
Thrombocytopenia Hospitalization 70 Female 6/23/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Viral Infection Hospitalization 6/1/2010 67 Female 6/25/2010 Other Health Professional United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 6/29/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Vision Blurred Other Serious 4/19/2010 41 Female 6/29/2010 Other Health Professional Netherlands
Primary
Concomitant
Drug Ineffective 11/1/2007 81 Male 195 lb 6/29/2010 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 6/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 7/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 65 Male 7/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Skin Ulcer Other Serious 9/1/2006 79 Male 152 lb 7/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 1/18/2010 69 Female 7/5/2010 United States
Primary
Concomitant
Pyrexia Hospitalization 6/1/2010 67 Female 7/6/2010 Other Health Professional United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization Female 7/7/2010 Other Health Professional Israel
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 7/9/2010 Physician United Kingdom
Primary
Secondary
Renal Impairment Other Serious 65 Male 7/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Hypertension Other Serious 11/1/2009 40 Female 252 lb 7/19/2010 Other Health Professional United States
Primary
Concomitant
Pain 5/1/2009 78 Female 145 lb 7/31/2010 Consumer United States
Primary
Secondary
Concomitant
Atrioventricular Block Second Degree Life Threatening 7/30/2010 67 8/26/2010 Other Health Professional United Kingdom
Primary
Concomitant
Suicidal Ideation Other Serious 7/1/2010 Female 8/25/2010 Consumer United States
Primary
Concomitant
Flushing 1/1/2004 52 Male 215 lb 9/14/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2009 49 Female 234 lb 9/14/2010 Consumer United States
Primary
Concomitant
Headache 12/1/2009 57 Female 203 lb 9/14/2010 Consumer United States
Primary
Concomitant
Renal Impairment Other Serious 65 Male 9/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 60 Female 150 lb 9/20/2010 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 48 Male 9/29/2010 Consumer United States
Primary
Concomitant
Syncope Hospitalization 78 Male 209 lb 9/30/2010 Pharmacist United States
Primary
Concomitant
Suicidal Ideation Disability 8/11/2010 52 Male 252 lb 10/1/2010 Physician New Zealand
Primary
Secondary
Concomitant
Chills Other Serious 71 Female 10/5/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 1/1/2007 54 Male 381 lb 10/7/2010 Lawyer United States
Primary
Concomitant

Drug Data