Ibuprofen combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Electrocardiogram St Segment Elevation Other Serious 10/5/2005 59 Male 181 lb 1/17/2006 Consumer United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 6/28/2005 Male 197 lb 2/1/2006 United States
Primary
Secondary
Concomitant
Bradycardia Life Threatening 10/6/2005 59 Male 202 lb 12/29/2005 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 11/30/2005 Male 153 lb 1/3/2006 Other Health Professional United States
Primary
Concomitant
Neuropathy Peripheral Required Intervention 1/15/2006 Male 400 lb 2/3/2006 Consumer United States
Primary
Concomitant
Faeces Discoloured Hospitalization 10/24/2005 72 Male 296 lb 10/25/2005 Pharmacist United States
Primary
Concomitant
Paraesthesia Hospitalization 12/22/2005 72 Female 99 lb 2/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Cushing's Syndrome Other Serious 54 Male 3/29/2006 Consumer United States
Primary
Concomitant
Pneumonitis Hospitalization 3/27/2006 72 Male 75 lb 4/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Hospitalization 3/27/2006 72 Male 75 lb 4/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Disorder Hospitalization 3/27/2006 72 Male 75 lb 4/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Melaena Hospitalization 2/10/2006 89 Female 4/20/2006 Physician
Primary
Secondary
Concomitant
Myalgia Other Serious 3/7/2006 70 Male 252 lb 3/8/2006 Pharmacist United States
Primary
Concomitant
Weight Increased Disability 2/1/2006 59 Female 154 lb 4/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Skin Disorder Hospitalization 3/27/2006 72 Male 75 lb 5/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 3/17/2006 70 Male 5/10/2006 United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 3/1/2006 61 Male 5/19/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 2/1/2006 64 Male 214 lb 5/26/2006 Physician Germany
Primary
Concomitant
Dry Mouth Other Serious 4/3/2006 62 Male 207 lb 4/7/2006 Pharmacist United States
Primary
Concomitant
Stem Cell Transplant Death 2/1/2004 50 Male 5/25/2006 Consumer United States
Primary
Concomitant
Personality Change Hospitalization 6/3/2006 59 Male 217 lb 6/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pollakiuria 73 Female 6/19/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/3/2005 42 Male 1/25/2006 United States
Primary
Concomitant
Pneumonia 1/1/2006 54 Female 166 lb 7/12/2006 Consumer United States
Primary
Concomitant
Oesophagitis Other Serious 61 Male 8/14/2006 Denmark
Primary
Secondary
Concomitant
Small Intestinal Haemorrhage Hospitalization 6/12/2006 64 Male 198 lb 7/14/2006 Pharmacist United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 5/13/2006 49 Male 250 lb 6/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 8/24/2006 Male 185 lb 9/6/2006 Pharmacist United States
Primary
Concomitant
Drug Interaction Potentiation Death 2/24/2006 85 Female 9/14/2006 Physician United States
Primary
Concomitant
Interacting
Stomach Discomfort Other Serious 1/1/2004 62 Male 250 lb 9/11/2006 United States
Primary
Secondary
Concomitant
Myalgia Other Serious 8/8/2006 60 Male 201 lb 9/15/2006 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 9/13/2006 45 Male 268 lb 9/20/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 3/23/2005 53 Male 11/6/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 11/1/2005 50 Male 209 lb 11/13/2006 United States
Primary
Concomitant
Sinus Disorder Hospitalization 12/1/2002 57 Male 11/16/2006 Physician United States
Primary
Concomitant
Skin Disorder Hospitalization 3/27/2006 72 Male 75 lb 12/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Synovial Fluid Analysis Hospitalization 8/26/2006 Male 12/22/2006 Other Health Professional Belgium
Primary
Concomitant
Death Death 3/13/2006 70 Female 12/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 3/13/2006 70 Female 12/20/2006 United Kingdom
Primary
Concomitant
Death Other Serious 3/13/2006 70 Female 12/28/2006 United Kingdom
Primary
Concomitant
Death Death 3/13/2006 70 Female 1/2/2007 United Kingdom
Primary
Concomitant
Gastric Ulcer Haemorrhage Other Serious 12/14/2006 56 Male 1/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 12/14/2006 56 Male 1/5/2007 United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 12/14/2006 56 Male 1/9/2007 United Kingdom
Primary
Concomitant
Oligodendroglioma Hospitalization 3/18/2005 66 Female 181 lb 1/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 12/14/2006 56 Male 1/16/2007 United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 12/14/2006 56 Male 1/16/2007 United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 12/14/2006 56 Male 1/16/2007 United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 12/14/2006 56 Male 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stent Placement Life Threatening 6/18/2006 60 Male 202 lb 1/19/2007 Physician United States
Primary
Concomitant
Appendicitis Hospitalization 8/12/2006 37 Male 1/25/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Speech Disorder Other Serious 11/1/2006 43 Female 182 lb 1/27/2007 Physician United Kingdom
Primary
Concomitant
Spontaneous Penile Erection Other Serious 1/1/2004 72 Male 179 lb 11/14/2006 United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 10/18/2006 66 Male 251 lb 1/30/2007 Pharmacist United States
Primary
Concomitant
Femoral Neck Fracture Hospitalization 3/1/2004 Female 2/2/2007 Other Health Professional Germany
Primary
Concomitant
Polydipsia Psychogenic Hospitalization 10/12/2006 69 Male 2/13/2007 Pharmacist United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 2/9/2007 61 Male 283 lb 2/16/2007 Pharmacist United States
Primary
Secondary
Concomitant
Anal Cancer Life Threatening 65 Female 139 lb 2/22/2007 Physician United Kingdom
Primary
Concomitant
Coronary Artery Disease Hospitalization 12/7/2006 Male 181 lb 2/22/2007 Physician Germany
Primary
Concomitant
Speech Disorder Hospitalization 11/1/2006 43 Female 181 lb 3/8/2007 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious 42 Male 11/13/2006 Physician United States
Primary
Concomitant
Renal Artery Stenosis Other Serious 3/3/2006 75 Male 198 lb 4/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Umbilical Hernia Hospitalization 8/12/2006 37 Male 4/5/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Speech Disorder Hospitalization 11/1/2006 43 Female 179 lb 4/9/2007 Physician United Kingdom
Primary
Concomitant
Skin Ulcer Other Serious 2/13/2007 62 Male 2/27/2007 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 241 lb 4/11/2007 Consumer United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 2/20/2007 63 Male 150 lb 4/9/2007 United States
Primary
Concomitant
Hypotension Hospitalization 1/4/2007 77 Male 3/1/2007 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 3/20/2007 52 Male 4/9/2007 Denmark
Primary
Concomitant
Vomiting Hospitalization 1/22/2007 Female 170 lb 3/30/2007 Pharmacist United States
Primary
Concomitant
Joint Swelling Other Serious 3/10/2007 75 Female 134 lb 4/12/2007 United Kingdom
Primary
Concomitant
Renal Artery Stenosis Other Serious 3/3/2006 75 Male 198 lb 4/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Joint Swelling Other Serious 3/10/2007 75 Female 134 lb 4/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Myalgia Other Serious 4/9/2007 62 Male 203 lb 4/10/2007 Pharmacist United States
Primary
Concomitant
Drug Ineffective Other Serious 4/1/2007 Female 230 lb 5/3/2007 Consumer United States
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 12/22/2005 72 Female 99 lb 5/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Melaena Hospitalization 3/26/2007 77 Male 5/8/2007 Pharmacist United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Life Threatening 3/24/2007 Male 151 lb 5/10/2007 Pharmacist United States
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased Hospitalization 5/9/2007 46 Male 280 lb 5/23/2007 Consumer United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 4/27/2007 67 Male 5/25/2007 Other Health Professional United States
Primary
Concomitant
Leukocytosis 5/23/2007 60 Male 169 lb 5/31/2007 Pharmacist United States
Primary
Concomitant
Lacunar Infarction Hospitalization 5/9/2007 Male 280 lb 6/11/2007 Physician United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 39 Male 6/25/2007 Consumer Italy
Primary
Secondary
Stress Other Serious 4/1/2007 53 Female 128 lb 7/3/2007 Consumer United States
Primary
Secondary
Concomitant
Wound Dehiscence Hospitalization 3/8/2007 Female 143 lb 7/9/2007 Physician United Kingdom
Primary
Concomitant
Pleural Effusion Other Serious 6/1/2006 7/11/2007 Consumer United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 39 Male 7/11/2007
Primary
Secondary
Myalgia Disability 60 Female 154 lb 7/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 7/16/2006 Male 293 lb 7/16/2007 United Kingdom
Primary
Concomitant
Haemorrhage Required Intervention 6/27/2007 84 Male 153 lb 7/18/2007 Pharmacist United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 12/7/2006 Male 181 lb 8/7/2007 Physician Germany
Primary
Concomitant
Drug Effect Decreased 6/1/2007 85 Male 165 lb 7/10/2007 Consumer United States
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization 11/15/2005 Female 106 lb 8/10/2007 Physician United Kingdom
Primary
Concomitant
Metabolic Acidosis Other Serious 1/1/2007 73 Female 9/18/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Metabolic Acidosis Life Threatening 1/1/2007 73 Female 9/24/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Life Threatening 1/1/2007 73 Female 9/19/2007 United Kingdom
Primary
Concomitant
Urinary Tract Infection Life Threatening 1/1/2007 73 Female 154 lb 9/21/2007 United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Life Threatening 1/1/2007 73 Female 9/21/2007 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 73 Female 9/15/2007 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 73 Female 154 lb 9/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 1/1/2004 80 Female 10/1/2007 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 73 Female 9/26/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Ileus Hospitalization Female 10/3/2007 Pharmacist United Kingdom
Primary
Concomitant
Interacting
Faeces Discoloured Other Serious Male 10/4/2007 Pharmacist United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 251 lb 10/5/2007 Physician United States
Primary
Concomitant
Appendicitis Hospitalization 8/12/2006 37 Male 285 lb 10/8/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Viral Infection Hospitalization 2/22/2005 35 Male 10/8/2007 Other Health Professional United States
Primary
Concomitant
Psychotic Disorder Death 6/1/2007 Male 195 lb 10/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 9/12/2007 67 Female 170 lb 10/30/2007 Consumer United Kingdom
Primary
Concomitant
Cerebrovascular Accident Life Threatening 7/5/2007 72 Male 273 lb 10/31/2007 Consumer United Kingdom
Primary
Concomitant
Nodal Marginal Zone B-cell Lymphoma Other Serious 10/15/2007 Female 152 lb 11/7/2007 United States
Primary
Concomitant
Liver Transplant Hospitalization 11/12/2007 Other Health Professional Sweden
Primary
Secondary
Drug Ineffective Hospitalization 10/14/2007 84 Female 11/20/2007 United Kingdom
Primary
Concomitant
Tachycardia Other Serious 74 Male 11/30/2007 Physician Germany
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 5/6/2007 Male 154 lb 12/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Death Other Serious Male 121 lb 12/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia 8/1/2007 Female 200 lb 12/14/2007 United States
Primary
Concomitant
Accidental Exposure 9/20/2007 Female 140 lb 12/14/2007 Consumer United States
Primary
Concomitant
Skin Irritation 8/1/2007 Male 12/14/2007 United States
Primary
Secondary
Concomitant
Injection Site Bruising 11/7/2007 Female 230 lb 12/14/2007 United States
Primary
Concomitant
Overdose Hospitalization 10/14/2007 84 Female 12/14/2007 Pharmacist Denmark
Primary
Concomitant
Gastric Haemorrhage Other Serious 4/27/2007 67 Male 12/17/2007 United Kingdom
Primary
Concomitant
Overdose Hospitalization 10/14/2007 84 Female 12/20/2007 United Kingdom
Primary
Concomitant
Tremor Other Serious 1/1/2007 Female 148 lb 1/28/2008 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 7/16/2006 Male 293 lb 2/6/2008 United Kingdom
Primary
Concomitant
General Physical Health Deterioration Hospitalization 10/15/2007 Female 132 lb 2/7/2008 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Life Threatening 10/1/2007 61 Female 2/12/2008 Other Health Professional Spain
Primary
Concomitant
Interacting
Hypothermia Other Serious 10/16/2007 Male 121 lb 2/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rash Hospitalization 7/17/2006 Male 293 lb 2/26/2008 United Kingdom
Primary
Concomitant
Bradycardia Other Serious 1/24/2008 Male 174 lb 2/28/2008 Pharmacist United States
Primary
Concomitant
Hypertension Other Serious 2/27/2008 82 3/12/2008 Consumer United States
Primary
Concomitant
Hypertension Other Serious 2/27/2008 82 3/13/2008 Consumer United States
Primary
Concomitant
Tongue Haemorrhage Other Serious 1/14/2008 74 Male 3/6/2008 United Kingdom
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 151 lb 3/14/2008 United States
Primary
Concomitant
Rash 12/1/2007 Female 180 lb 3/14/2008 United States
Primary
Concomitant
Blood Potassium Increased Required Intervention 1/13/2008 41 Male 331 lb 2/20/2008 United States
Primary
Concomitant
Knee Arthroplasty Other Serious 4/27/2007 67 Male 3/24/2008 Consumer United Kingdom
Primary
Concomitant
Suicidal Ideation Other Serious 3/13/2008 66 Male 3/27/2008 Physician Germany
Primary
Secondary
Weight Increased Other Serious 1/1/2008 Female 151 lb 4/4/2008 United States
Primary
Concomitant
Hypoglycaemia Other Serious 77 Female 172 lb 4/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Hypoglycaemia Other Serious 77 Female 172 lb 4/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Oesophagitis Hospitalization 7/5/2002 60 Male 4/21/2008 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Other Serious 6/1/2007 Male 282 lb 4/16/2008 Consumer United States
Primary
Concomitant
General Physical Health Deterioration Hospitalization 10/15/2007 Female 132 lb 4/29/2008 Physician United Kingdom
Primary
Concomitant
Hypertension Other Serious 2/27/2008 82 5/26/2008 Consumer United States
Primary
Concomitant
Multiple Sclerosis Relapse Hospitalization 1/1/2006 58 Male 178 lb 5/23/2008 United States
Primary
Concomitant
Pruritus Generalised 1/1/2007 69 Male 365 lb 4/10/2008 Consumer United States
Primary
Concomitant
Skin Discolouration Life Threatening 3/1/2008 62 Male 6/16/2008 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 4/8/2008 Male 321 lb 7/2/2008 Physician United States
Primary
Concomitant
Syncope Other Serious 7/11/2007 65 Female 175 lb 6/9/2008 Consumer United States
Primary
Concomitant

Drug Data