Cyclosporine combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Impairment Other Serious 7/25/2005 30 Female 1/3/2006 Brazil
Primary
Concomitant
Urosepsis Hospitalization 10/10/2004 65 Female 159 lb 1/27/2006 Physician Israel
Primary
Secondary
Concomitant
Proteinuria Other Serious 7/7/2005 50 Female 1/30/2006 Brazil
Primary
Secondary
Concomitant
Proteinuria Other Serious 7/5/2005 50 Female 1/30/2006 Brazil
Primary
Secondary
Concomitant
Urosepsis Hospitalization 10/10/2004 65 Female 159 lb 2/13/2006 Physician Israel
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 4/8/2005 62 Male 3/9/2006 Consumer Australia
Primary
Secondary
Refusal Of Treatment By Patient Hospitalization 1/10/2006 39 Male 3/7/2006 Brazil
Primary
Concomitant
Rhabdomyolysis Life Threatening 1/19/2006 57 Female 245 lb 1/20/2006 United States
Primary
Secondary
Upper Respiratory Tract Infection Life Threatening 5/12/2005 Male 4/27/2006 Pharmacist United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Life Threatening 5/12/2005 Male 4/27/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 3/13/2006 57 Male 4/24/2006 Brazil
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/10/2006 39 Male 4/24/2006 Brazil
Primary
Concomitant
Rhabdomyolysis Death 64 Female 4/20/2006 Other Health Professional Germany
Primary
Secondary
Post Procedural Complication Hospitalization 3/29/2006 66 Male 5/5/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Hospitalization 3/29/2006 66 Male 5/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 3/13/2006 57 Male 5/22/2006 Other Health Professional Brazil
Primary
Concomitant
Urinary Retention Hospitalization 9/26/2005 60 Male 5/24/2006 Brazil
Primary
Secondary
Concomitant
Kidney Transplant Rejection Other Serious 10/13/2005 43 Male 6/2/2006 Other Health Professional Brazil
Primary
Concomitant
Rhabdomyolysis Other Serious 74 Female 6/26/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Death 64 Female 6/28/2006 Other Health Professional Germany
Primary
Secondary
Urinary Tract Infection Enterococcal Other Serious 9/26/2005 23 Male 7/11/2006 Brazil
Primary
Secondary
Concomitant
Sepsis Required Intervention 8/13/2005 58 Male 194 lb 7/8/2006 Pharmacist United States
Primary
Concomitant
Splenic Infarction Hospitalization 45 Male 7/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 4/1/2000 53 Male 7/21/2006 Other Health Professional Greece
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 4/17/2006 55 Male 261 lb 5/10/2006 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 69 Male 10/3/2006 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/25/2002 80 Male 10/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Death 64 Female 10/16/2006 Germany
Primary
Secondary
Urosepsis Hospitalization 10/10/2004 65 Male 159 lb 10/23/2006 Physician Israel
Primary
Secondary
Concomitant
Rhabdomyolysis Death 64 Female 10/24/2006 Germany
Primary
Secondary
Hemiparesis Other Serious 3/18/2006 72 Female 183 lb 10/31/2006 Pharmacist United States
Primary
Concomitant
Convulsion Other Serious 7/9/2006 72 Female 11/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Kidney Transplant Rejection Other Serious 10/10/2005 61 Female 11/30/2006 Brazil
Primary
Concomitant
Rhabdomyolysis Hospitalization 72 Male 12/28/2006 Other Health Professional Italy
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/20/2006 74 Male 198 lb 1/11/2007 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/1/2006 Male 1/22/2007 Physician Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 12/20/2006 74 Male 198 lb 1/18/2007 Physician United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Hospitalization 9/6/2005 Male 1/30/2007 Physician United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/1/2006 74 Male 2/14/2007 United States
Primary
Secondary
Concomitant
Interacting
Sinus Tachycardia Death 55 Male 2/13/2007 Physician United States
Primary
Concomitant
Rhabdomyolysis Other Serious 9/14/2006 51 Male 272 lb 3/6/2007 Pharmacist United States
Primary
Secondary
Concomitant
Lentigo Maligna Stage Unspecified Other Serious 2/16/2007 Male 191 lb 3/14/2007 Physician Australia
Primary
Concomitant
Nephritis Interstitial Other Serious 4/29/2005 Female 208 lb 3/23/2007 Physician Brazil
Primary
Concomitant
Rhabdomyolysis Hospitalization Male 4/6/2007 Italy
Primary
Secondary
White Blood Cell Count Increased Hospitalization 70 Male 4/24/2007 Italy
Primary
Secondary
White Blood Cell Count Increased Hospitalization 70 Male 4/24/2007 Italy
Primary
Secondary
Sepsis Death 66 Male 5/2/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 69 Male 4/30/2007 Other Health Professional Spain
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 5/1/2006 73 Male 5/10/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 66 Male 5/30/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 66 Male 6/1/2007 Other Health Professional United States
Primary
Secondary
Rhabdomyolysis Hospitalization Male 7/12/2007 Physician Belgium
Primary
Concomitant
Rhabdomyolysis Life Threatening 6/15/2007 Male 148 lb 7/27/2007 Physician Belgium
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 66 Male 7/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 4/26/2007 79 Male 8/9/2007 Pharmacist United States
Primary
Secondary
Weight Decreased Hospitalization 66 Male 8/9/2007 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Scalded Skin Syndrome Hospitalization 5/8/2007 55 Male 8/23/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonitis Life Threatening 7/20/2006 Male 9/5/2007 Other Health Professional Australia
Primary
Concomitant
Rhabdomyolysis 8/7/2007 46 Male 8/22/2007 United States
Primary
Secondary
Kaposi's Sarcoma Other Serious 8/12/1998 45 Female 10/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Required Intervention 10/6/2007 78 Male 10/15/2007 Pharmacist United States
Primary
Secondary
Weight Decreased Other Serious 66 Male 11/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 64 Male 12/5/2007 United States
Primary
Secondary
Concomitant
Rhabdomyolysis Required Intervention 9/8/2007 27 Male 12/3/2007 Pharmacist United States
Primary
Secondary
Myopathy Toxic Death 66 Male 12/18/2007 United States
Primary
Secondary
Concomitant
Septic Shock Death 66 Male 12/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 52 Female 12/18/2007 Turkey
Primary
Secondary
Concomitant
Weight Decreased Death 66 Male 12/21/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Death 66 Male 12/21/2007 Physician United States
Primary
Secondary
Concomitant
Myopathy Toxic Other Serious 66 Male 12/31/2007 United States
Primary
Secondary
Rhabdomyolysis Hospitalization 66 Male 1/7/2008 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 66 Male 1/8/2008 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 64 Male 1/14/2008 United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 64 Male 259 lb 1/22/2008 Physician United States
Primary
Secondary
Concomitant
Lentigo Maligna Stage Unspecified Other Serious 2/16/2007 Male 191 lb 1/30/2008 Physician Australia
Primary
Concomitant
Weight Increased Hospitalization 64 Male 1/21/2008 Other Health Professional United States
Primary
Secondary
Rhabdomyolysis Hospitalization 64 Male 259 lb 1/25/2008 United States
Primary
Secondary
Concomitant
Uterine Polyp Other Serious 1/1/2008 Female 2/20/2008 Physician United States
Primary
Concomitant
Transplant Rejection Hospitalization 1/1/2006 64 Male 260 lb 2/21/2008
Primary
Secondary
Weight Decreased Other Serious 66 Male 2/19/2008 United States
Primary
Concomitant
Rhabdomyolysis Death 66 Male 2/26/2008 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 52 Female 2/22/2008 Physician Turkey
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious Female 3/3/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sinusitis 1/1/2008 Female 175 lb 3/15/2008 Consumer United States
Primary
Concomitant
Sepsis Death 66 Male 3/12/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Death 1/1/2008 66 Male 3/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Reticulocyte Count Increased Hospitalization 33 Male 3/26/2008 United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 66 Male 4/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Lentigo Maligna Stage Unspecified Other Serious 2/16/2007 Male 191 lb 4/21/2008 Physician Australia
Primary
Concomitant
Rhabdomyolysis Hospitalization 70 Female 5/1/2008 Physician Switzerland
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 66 Male 5/19/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 62 Male 6/13/2008 Physician Switzerland
Primary
Secondary
Concomitant
Weight Decreased Other Serious 66 Male 6/23/2008 Physician United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Life Threatening 8/1/2007 78 Male 214 lb 7/1/2008 Physician Germany
Primary
Secondary
Concomitant
Respiratory Tract Infection Other Serious 4/11/2004 Female 7/15/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Life Threatening 8/1/2007 78 Male 214 lb 7/21/2008 Physician Germany
Primary
Secondary
Concomitant
Myopathy Other Serious 62 Male 7/24/2008 Switzerland
Primary
Concomitant
Interacting
Weight Decreased Other Serious 62 Male 7/28/2008 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 4/27/2008 87 Male 329 lb 7/29/2008 Pharmacist United States
Primary
Secondary
Rhodococcus Infection Hospitalization 62 Male 7/31/2008 Switzerland
Primary
Secondary
Interacting
Wound Infection 73 Male 203 lb 7/29/2008 Consumer United States
Primary
Concomitant
Rhodococcus Infection Hospitalization 8/12/2008 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 7/9/2008 8/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 69 Male 8/11/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 7/9/2008 41 NotSpecified 8/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 7/9/2008 41 8/19/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Type 2 Diabetes Mellitus Life Threatening 8/1/2007 78 Male 214 lb 8/21/2008 Physician Germany
Primary
Secondary
Concomitant
Accidental Exposure Other Serious 11/1/2007 Female 94 lb 9/12/2008 Consumer United States
Primary
Concomitant
Polycythaemia Hospitalization 4/9/2008 32 Female 9/15/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Cholelithiasis Hospitalization 5/23/2008 Male 10/1/2008 Physician United States
Primary
Concomitant
Systemic Inflammatory Response Syndrome Life Threatening Male 10/13/2008 Physician Germany
Primary
Concomitant
Rhabdomyolysis Hospitalization 45 Male 10/21/2008 Other Health Professional United States
Primary
Secondary
Interacting
Subcutaneous Emphysema Other Serious 62 Male 11/19/2008
Primary
Secondary
Concomitant
Nausea Required Intervention 6/9/2008 39 Male 163 lb 7/8/2008 United States
Primary
Concomitant
Sputum Discoloured Hospitalization 1/1/2004 170 lb 11/25/2008 United States
Primary
Concomitant
Carpal Tunnel Syndrome Female 160 lb 12/12/2008 Physician United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 58 Female 12/26/2008 Canada
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/7/2009 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/9/2009 Other Health Professional United States
Primary
Interacting
Rhabdomyolysis Other Serious 56 Male 1/8/2009 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 56 Male 1/13/2009 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 56 Male 1/20/2009 Other Health Professional United States
Primary
Concomitant
Interacting
Rhabdomyolysis Other Serious 54 Male 1/30/2009 Other Health Professional Spain
Primary
Concomitant
Interacting
Ubiquinone Decreased Hospitalization 61 Female 2/3/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 56 Male 1/27/2009 Physician United States
Primary
Secondary
Concomitant
Product Quality Issue 7/1/2008 54 Male 180 lb 1/13/2009 Pharmacist United States
Primary
Concomitant
Ubiquinone Decreased Hospitalization 61 Female 2/5/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 56 Male 2/4/2009 United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 64 Male 259 lb 2/5/2009 Physician United States
Primary
Secondary
Concomitant
Ubiquinone Decreased Hospitalization 61 Female 2/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 56 Male 3/9/2009 Consumer United Kingdom
Primary
Secondary
Rhabdomyolysis Other Serious 3/9/2009 Spain
Primary
Interacting
Rhabdomyolysis Other Serious 56 Male 3/10/2009 Physician United States
Primary
Secondary
Concomitant
Ubiquinone Decreased Hospitalization 61 Female 3/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 3/17/2009 Spain
Primary
Interacting
Rhabdomyolysis Hospitalization 56 Male 3/23/2009 United States
Primary
Concomitant
Aplasia Pure Red Cell Hospitalization 3/29/2006 Male 3/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/1/2008 Male 3/30/2009 Other Health Professional United States
Primary
Secondary
Rhabdomyolysis Hospitalization 56 Male 4/2/2009 Other Health Professional United States
Primary
Secondary
Urinary Tract Infection Other Serious 8/5/2003 Female 123 lb 4/3/2009 Physician Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious Male 3/24/2009 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 56 Male 4/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 56 Male 4/3/2009 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/1/2008 56 Male 4/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Hospitalization 3/29/2006 Male 4/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Paralysis Other Serious 58 Male 4/14/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Paralysis Other Serious 12/1/2008 58 Male 4/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 56 Male 4/16/2009
Primary
Secondary
Ubiquinone Decreased Hospitalization 61 Female 4/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Paralysis Other Serious 12/1/2008 58 Male 4/20/2009 United Kingdom
Primary
Secondary
Concomitant

Drug Data