Fluorouracil combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hypophosphataemia Life Threatening 8/31/2005 61 Female 4/20/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypophosphataemia Life Threatening 8/31/2005 61 Female 5/1/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/28/2005 45 Female 139 lb 2/24/2006 United States
Primary
Concomitant
Leukocytoclastic Vasculitis Hospitalization 4/20/2006 Male 205 lb 5/23/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/3/2005 39 Female 128 lb 5/24/2006 Physician United Kingdom
Primary
Concomitant
Leukocytoclastic Vasculitis Hospitalization 4/20/2006 Male 205 lb 5/26/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/4/2006 72 Male 176 lb 6/7/2006 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/4/2006 72 Male 176 lb 6/7/2006 Physician Germany
Primary
Secondary
Concomitant
White Blood Cells Urine Positive Hospitalization 5/2/2006 71 Female 185 lb 6/12/2006 Physician Spain
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Hospitalization 4/20/2006 63 Male 6/16/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 4/4/2006 74 Female 7/12/2006 United Kingdom
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 4/4/2006 74 Female 7/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lung Infiltration Hospitalization 5/14/2006 78 Male 7/31/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/9/2006 73 Male 187 lb 8/31/2006 Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/24/2006 73 Male 187 lb 9/19/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Yersinia Infection Hospitalization 7/24/2006 73 Male 187 lb 9/30/2006 Germany
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Hospitalization 52 Female 11/13/2006 Other Health Professional Israel
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/7/2006 57 Male 158 lb 11/17/2006 Pharmacist United States
Primary
Concomitant
Raynaud's Phenomenon Other Serious 57 Male 176 lb 12/7/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/3/2005 39 Female 128 lb 12/12/2006 Physician United Kingdom
Primary
Concomitant
Stridor Life Threatening 11/27/2006 67 Male 234 lb 1/24/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Confusional State Hospitalization 3/1/2007 Male 214 lb 3/8/2007 Other Health Professional Poland
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 12/5/2006 70 Male 183 lb 3/15/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Hypophosphataemia Life Threatening 8/31/2005 61 Female 3/16/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Night Sweats Hospitalization 12/3/2006 70 Male 3/19/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/28/2007 79 Male 3/29/2007 Physician United States
Primary
Secondary
Concomitant
Night Sweats Hospitalization 12/3/2006 70 Male 4/6/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 12/5/2006 70 Male 183 lb 4/10/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Hospitalization 4/20/2006 Male 205 lb 4/11/2007 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Night Sweats Hospitalization 12/3/2006 70 Male 4/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Confusional State Hospitalization 3/1/2007 Male 214 lb 4/24/2007 Other Health Professional Poland
Primary
Secondary
Concomitant
Dermatitis Infected Hospitalization 8/23/2006 Male 5/4/2007 Physician Australia
Primary
Concomitant
Chest Pain Hospitalization 3/15/2007 Male 5/8/2007 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/3/2005 39 Female 128 lb 5/12/2007 Physician United Kingdom
Primary
Concomitant
Influenza Serology Positive Hospitalization 3/23/2007 52 Male 5/8/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/28/2007 79 Male 5/17/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/28/2007 79 Male 5/17/2007 Physician United States
Primary
Secondary
Concomitant
Death Death 5/24/2006 Male 159 lb 6/14/2007 Other Health Professional France
Primary
Secondary
Concomitant
Presyncope Other Serious 6/19/2007 Male 175 lb 6/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Hypophosphataemia Life Threatening 8/31/2005 61 Female 6/27/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 3/1/2007 Male 214 lb 7/18/2007 Other Health Professional Poland
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 3/1/2007 Male 214 lb 7/23/2007 Other Health Professional Poland
Primary
Secondary
Concomitant
Cerebral Ischaemia Hospitalization 7/1/2007 71 Male 8/16/2007 Physician United States
Primary
Secondary
Concomitant
Haematoma Other Serious 67 Male 10/9/2007 Physician Germany
Primary
Secondary
Concomitant
Haematoma Other Serious 67 Male 10/30/2007 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/22/2007 66 Female 12/3/2007 Belgium
Primary
Secondary
Concomitant
Sudden Death Death 12/15/2007 Male 152 lb 1/2/2008 Other Health Professional Belgium
Primary
Secondary
Concomitant
Sudden Death Death 12/15/2007 Male 152 lb 1/18/2008 Other Health Professional Belgium
Primary
Secondary
Concomitant
Sudden Death Death 12/15/2007 Male 152 lb 1/23/2008 Other Health Professional Belgium
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 4/6/2007 Male 1/29/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 1/28/2008 Female 151 lb 2/4/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 12/10/2007 72 Male 2/20/2008 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 12/10/2007 72 Male 2/25/2008 Physician Germany
Primary
Secondary
Concomitant
Hypophosphataemia Life Threatening 8/31/2005 61 Female 3/18/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Other Serious 4/30/2006 Male 205 lb 3/27/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Carotid Artery Occlusion Hospitalization 3/27/2008 60 4/9/2008 Other Health Professional
Primary
Secondary
Concomitant
Carotid Artery Occlusion Hospitalization 3/27/2008 60 Male 4/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vitamin B12 Deficiency Hospitalization 3/27/2008 60 Male 4/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 1/28/2008 Female 151 lb 5/13/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 1/28/2008 Female 151 lb 6/4/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/22/2008 69 Female 108 lb 6/13/2008 Consumer United States
Primary
Secondary
Concomitant
Dysphagia Hospitalization 5/15/2008 82 Male 5/24/2008 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 11/22/2007 Female 165 lb 7/14/2008 Physician Belgium
Primary
Secondary
Concomitant
Anaphylactic Shock Life Threatening 1/18/2008 Male 7/22/2008 Physician Japan
Primary
Secondary
Concomitant
Prinzmetal Angina Other Serious 12/9/2007 Male 7/23/2008 Physician Japan
Primary
Secondary
Concomitant
Oropharyngeal Pain Hospitalization 5/31/2008 Male 7/28/2008 Physician Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 8/17/2008 75 Female 176 lb 9/9/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 9/2/2008 81 Male 183 lb 9/17/2008 Consumer United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 9/2/2008 81 Male 183 lb 9/24/2008 Consumer United States
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 7/31/2008 68 Male 123 lb 9/29/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Ileus Life Threatening 1/18/2008 Male 220 lb 10/9/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 66 Male 10/21/2008 Other Health Professional Japan
Primary
Concomitant
Pyrexia Hospitalization 10/6/2008 Male 207 lb 10/23/2008 Physician Belgium
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 10/14/2008 Male 10/23/2008 Singapore
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/6/2008 79 Male 207 lb 10/31/2008 Physician Belgium
Primary
Secondary
Concomitant
Lung Abscess Hospitalization 10/14/2008 Male 11/3/2008 Singapore
Primary
Secondary
Concomitant
Lung Abscess Hospitalization 10/14/2008 Male 11/7/2008 Physician Singapore
Primary
Secondary
Concomitant
Cardiomyopathy Hospitalization 4/1/2008 68 Female 11/17/2008 Physician Switzerland
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/6/2008 79 Male 207 lb 11/24/2008 Physician Belgium
Primary
Secondary
Concomitant
Cardiomyopathy Hospitalization 4/18/2008 67 Female 11/25/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiomyopathy Hospitalization 4/1/2008 68 Female 11/25/2008 Physician Switzerland
Primary
Secondary
Concomitant
Cardiomyopathy Hospitalization 4/1/2008 Female 11/25/2008 Physician Switzerland
Primary
Secondary
Concomitant
Hypercreatinaemia Hospitalization 12/5/2008 79 Male 207 lb 12/12/2008 Physician Belgium
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/25/2008 Male 185 lb 12/19/2008 Physician Denmark
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/6/2008 79 Male 207 lb 12/23/2008 Physician Belgium
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/7/2007 Male 144 lb 12/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hypercreatinaemia Hospitalization 12/5/2008 79 Male 207 lb 12/29/2008 Physician Belgium
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 11/6/2008 Male 12/30/2008 Physician United Kingdom
Primary
Concomitant
Gastroenteritis Hospitalization 12/3/2005 Male 159 lb 2/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypercreatinaemia Hospitalization 12/5/2008 79 Male 207 lb 2/5/2009 Physician Belgium
Primary
Secondary
Concomitant
Glossodynia Hospitalization 5/31/2008 Male 2/26/2009 Physician Germany
Primary
Concomitant
Mucosal Inflammation Hospitalization 5/26/2008 Male 3/23/2009 Physician Germany
Primary
Concomitant
Oropharyngeal Pain Hospitalization 3/25/2009 59 Male 241 lb 4/3/2009 United States
Primary
Secondary
Concomitant
Oropharyngeal Pain Hospitalization 3/25/2009 59 Male 242 lb 4/17/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Death 2/5/2009 Male 192 lb 4/22/2009 Other Health Professional Poland
Primary
Secondary
Concomitant
Lung Abscess Hospitalization 10/14/2008 4/30/2009 Physician Singapore
Primary
Secondary
Concomitant
Oropharyngeal Pain Hospitalization 3/25/2009 59 Male 242 lb 5/5/2009 Physician United States
Primary
Secondary
Concomitant
Lung Abscess Hospitalization 10/14/2008 Male 5/8/2009 Physician Singapore
Primary
Secondary
Concomitant
Oropharyngeal Pain Hospitalization 3/25/2009 59 Male 242 lb 5/8/2009 Physician United States
Primary
Secondary
Concomitant
Lung Abscess Hospitalization 10/14/2008 62 5/13/2009 Physician Singapore
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 4/30/2009 67 Female 6/1/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 4/30/2009 67 6/8/2009 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/15/2009 Female 6/8/2009 Physician United States
Primary
Concomitant
Hypoaesthesia Hospitalization 11/5/2008 Female 6/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 4/30/2009 67 Female 6/18/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 6/28/2008 Female 130 lb 6/29/2009 Other Health Professional Portugal
Primary
Secondary
Concomitant
Cellulitis Hospitalization 6/23/2009 78 Male 172 lb 7/7/2009 United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 4/30/2009 67 7/20/2009 Physician Japan
Primary
Secondary
Concomitant
Lung Abscess Hospitalization 10/14/2008 62 7/20/2009 Physician Singapore
Primary
Secondary
Concomitant
Cellulitis Hospitalization 6/23/2009 78 Male 172 lb 8/20/2009 Physician United States
Primary
Secondary
Concomitant
Cellulitis Hospitalization 6/23/2009 78 Male 172 lb 8/28/2009 Physician United States
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 6/23/2009 78 Male 168 lb 9/8/2009 Physician United States
Primary
Secondary
Concomitant
Road Traffic Accident Hospitalization 2/23/2001 59 Male 190 lb 9/23/2009 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/22/2006 Female 10/12/2009 Consumer Canada
Primary
Concomitant
Respiratory Failure Life Threatening 12/4/2008 Male 10/27/2009 Physician United States
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 6/23/2009 78 Male 168 lb 10/28/2009 United States
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 11/27/2006 Male 234 lb 11/10/2009 Consumer France
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 11/27/2006 67 Male 11/10/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 12/3/2009 73 Male 163 lb 2/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 6/23/2009 78 Male 168 lb 3/16/2010 United States
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 6/23/2009 78 Male 168 lb 4/6/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/3/2010 50 Female 136 lb 4/15/2010 Physician United States
Primary
Secondary
Concomitant
Lung Abscess Hospitalization 10/14/2008 62 Male 137 lb 4/23/2010 Physician Singapore
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/6/2010 74 Female 4/30/2010 Physician Germany
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 10/28/2009 68 Male 5/6/2010 Physician United States
Primary
Secondary
Concomitant
Lung Abscess Hospitalization 10/14/2008 62 Male 5/11/2010 Physician Singapore
Primary
Secondary
Concomitant
Pyrexia Life Threatening 1/6/2010 69 Female 203 lb 5/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 1/6/2010 69 Female 6/7/2010 Physician United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 5/7/2010 68 Male 168 lb 8/3/2010 Physician Germany
Primary
Secondary
Concomitant
Drug Hypersensitivity Other Serious 3/22/2010 52 Female 8/10/2010 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 9/7/2010 74 Female 9/29/2010 Physician Germany
Primary
Secondary
Concomitant
Rash Other Serious 8/19/2010 79 Male 269 lb 10/7/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/22/2006 64 Female 10/8/2010 Consumer Canada
Primary
Concomitant
Bacterial Sepsis Hospitalization 10/30/2010 74 Male 190 lb 11/10/2010 United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 1/1/2010 63 Female 11/25/2010 Other Health Professional France
Primary
Secondary
Concomitant
Dermatitis Acneiform Hospitalization 9/9/2010 11/26/2010 Physician Japan
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 1/1/2010 62 Female 12/2/2010 Consumer France
Primary
Secondary
Concomitant
Skin Disorder Other Serious 9/23/2010 12/7/2010 Japan
Primary
Secondary
Concomitant
Infection Hospitalization 12/6/2010 75 Male 139 lb 12/27/2010 Physician United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Hospitalization 7/24/2010 62 Male 252 lb 1/3/2011 Physician United States
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 6/23/2009 78 Male 167 lb 1/27/2011 Consumer United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 11/13/2010 73 1/28/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 12/10/2010 Male 170 lb 2/16/2011 Physician United States
Primary
Secondary
Concomitant
Cough Hospitalization 12/15/2010 65 Female 147 lb 3/8/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 11/13/2010 73 3/11/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Catheter Site Infection Hospitalization 2/16/2011 67 Male 251 lb 3/16/2011 Physician Germany
Primary
Secondary
Concomitant
Infection Hospitalization 3/2/2011 63 Male 3/21/2011 Physician France
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 6/23/2009 78 Male 167 lb 3/22/2011 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Exertional Hospitalization 5/22/2006 64 Female 3/24/2011 Consumer Canada
Primary
Concomitant
Acute Myeloid Leukaemia Hospitalization 7/24/2010 62 Male 252 lb 3/28/2011 Physician United States
Primary
Secondary
Concomitant

Drug Data