Hydroxychloroquine Sulfate combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Therapeutic Agent Toxicity Hospitalization 12/1/2005 Male 2/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 11/1/2005 Male 4/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 54 Female 11/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Drug Level Increased Other Serious 12/1/2006 65 Male 1/19/2007 United Kingdom
Primary
Secondary
Concomitant
Subcutaneous Emphysema Hospitalization 10/1/2003 66 Male 1/27/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Femoral Neck Fracture Hospitalization 3/1/2004 Female 2/2/2007 Other Health Professional Germany
Primary
Concomitant
Refractory Anaemia With An Excess Of Blasts Other Serious 76 Male 2/12/2007 United States
Primary
Concomitant
Refractory Anaemia With An Excess Of Blasts Other Serious 76 Male 3/20/2007 Other Health Professional United States
Primary
Concomitant
Staphylococcal Infection Death 2/15/2007 Male 132 lb 6/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Other Serious 1/1/2007 68 Female 152 lb 6/22/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Death 2/15/2007 Male 132 lb 7/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Other Serious 5/21/2007 68 Female 152 lb 6/29/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Refractory Anaemia Other Serious 1/1/2005 76 Male 9/19/2007 Other Health Professional United States
Primary
Concomitant
Pleurisy Hospitalization 5/9/2007 Male 214 lb 10/11/2007 United Kingdom
Primary
Concomitant
Rectal Cancer Life Threatening 8/1/2007 Female 187 lb 12/6/2007 United Kingdom
Primary
Concomitant
Rectal Cancer Other Serious 3/14/2007 Female 198 lb 12/18/2007 United Kingdom
Primary
Concomitant
Productive Cough Other Serious 1/31/2008 71 Male 176 lb 2/29/2008 Physician United Kingdom
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious 1/31/2008 71 Male 176 lb 3/1/2008 United Kingdom
Primary
Concomitant
Breast Cancer Hospitalization 1/1/2008 Female 245 lb 5/22/2008 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 3/1/2008 Female 5/23/2008 Physician Brazil
Primary
Concomitant
Thrombosis Hospitalization 6/1/2008 63 Male 6/4/2008 Consumer Canada
Primary
Concomitant
Throat Irritation 4/12/2008 Female 204 lb 6/12/2008 United States
Primary
Concomitant
Neutropenic Sepsis Death 71 Female 7/4/2008 Other Health Professional United Kingdom
Primary
Concomitant
Metastases To Liver Other Serious 3/28/2008 Female 123 lb 8/7/2008 Physician United Kingdom
Primary
Concomitant
Sinus Bradycardia Other Serious 7/7/2008 77 Female 131 lb 8/13/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 11/17/2008 Male 179 lb 11/17/2008 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 65 Female 12/1/2008 United States
Primary
Secondary
Concomitant
Procedural Complication 8/30/2008 Male 300 lb 12/12/2008 Consumer United States
Primary
Concomitant
Staphylococcal Skin Infection 7/1/2008 Female 220 lb 12/12/2008 Consumer United States
Primary
Concomitant
Sputum Discoloured 10/17/2008 Female 190 lb 12/12/2008 United States
Primary
Concomitant
Supraventricular Tachycardia Other Serious 10/21/2007 Female 176 lb 12/15/2008 Czech Republic
Primary
Concomitant
Wheezing Hospitalization 10/1/2008 56 Female 12/23/2008 Consumer United Kingdom
Primary
Secondary
Productive Cough Other Serious 1/6/2009 Female 117 lb 4/17/2009 United Kingdom
Primary
Concomitant
Productive Cough Hospitalization 1/6/2009 Female 117 lb 4/17/2009 United Kingdom
Primary
Concomitant
Thrombosis Other Serious 6/1/2008 63 Male 4/20/2009 Consumer Canada
Primary
Concomitant
Neutropenia Other Serious 3/1/2009 55 Female 130 lb 5/18/2009 Consumer United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 8/1/2009 Female 96 lb 8/11/2009 Physician Brazil
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 8/10/2009 United States
Primary
Concomitant
Sepsis Death 2/21/2009 Female 231 lb 8/17/2009 United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/13/2009 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/23/2009 Lawyer United States
Primary
Concomitant
Incorrect Dose Administered 8/30/2007 Female 196 lb 9/12/2009 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 1/1/2005 50 Female 10/8/2009 Other Health Professional United Kingdom
Primary
Concomitant
Cerebrovascular Accident Other Serious 50 Female 10/5/2009 Other Health Professional United Kingdom
Primary
Concomitant
Cerebrovascular Accident Other Serious 1/1/2005 50 Female 10/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 1/1/2005 50 Female 10/12/2009
Primary
Concomitant
Lipase Increased Required Intervention 9/15/2009 53 Female 143 lb 10/1/2009 Pharmacist United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 8/1/2009 Female 96 lb 11/2/2009 Physician Brazil
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 1/1/2005 50 Female 10/27/2009 United Kingdom
Primary
Concomitant
Cerebrovascular Accident Other Serious 1/1/2005 50 Female 11/3/2009 Other Health Professional United Kingdom
Primary
Concomitant
Inappropriate Schedule Of Drug Administration Hospitalization 10/26/2009 89 Female 11/20/2009 Pharmacist Canada
Primary
Concomitant
Thrombosis Other Serious 6/1/2008 63 Male 12/1/2009 Consumer Canada
Primary
Concomitant
Inappropriate Schedule Of Drug Administration Hospitalization 10/26/2009 89 Female 12/21/2009 Pharmacist Canada
Primary
Concomitant
Sepsis Life Threatening 5/12/2008 71 Female 1/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Swelling Hospitalization 7/1/2009 63 Female 278 lb 2/3/2010 Physician United States
Primary
Concomitant
Swelling Hospitalization 7/1/2009 63 Female 278 lb 2/12/2010 Physician United States
Primary
Concomitant
Facial Paresis Hospitalization 9/2/2008 Male 159 lb 2/25/2010 Consumer United Kingdom
Primary
Concomitant
Pain Other Serious 8/1/2008 Female 3/19/2010 Other Health Professional United Kingdom
Primary
Concomitant
Weight Bearing Difficulty Other Serious 1/1/2009 Female 3/24/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 6/23/2009 61 Female 170 lb 4/14/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 6/23/2009 61 Female 170 lb 4/15/2010 Consumer United States
Primary
Concomitant
Panic Attack Other Serious 1/1/2009 Female 4/19/2010 Consumer United Kingdom
Primary
Concomitant
Rash Hospitalization 1/1/2010 Female 4/21/2010 Consumer United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 11/20/2009 55 Female 152 lb 4/28/2010 Physician Philippines
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/20/2009 55 Female 152 lb 5/3/2010 Physician Philippines
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 7/1/2009 63 Female 278 lb 9/8/2010 Physician United States
Primary
Concomitant
Urticaria Other Serious 9/1/2008 10/21/2010 Physician United States
Primary
Concomitant
Respiratory Tract Haemorrhage Other Serious 9/24/2010 76 Female 12/1/2010 Italy
Primary
Secondary
Concomitant
Sinusitis 12/19/2010 Consumer United States
Primary
Concomitant
Sinusitis 4/5/2010 12/21/2010 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 4/21/2010 12/21/2010 Physician United States
Primary
Concomitant
Respiratory Tract Haemorrhage Other Serious 9/24/2010 76 Female 12/7/2010 Italy
Primary
Secondary
Concomitant
Muscle Spasms 4/13/2010 12/22/2010 Consumer United States
Primary
Concomitant
Sinus Headache 6/4/2010 12/22/2010 Consumer United States
Primary
Concomitant
Tooth Disorder 1/1/2006 56 Male 1/29/2011 Consumer United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 2/24/2011 73 Female 146 lb 3/29/2011 Physician Greece
Primary
Secondary
Concomitant
Chromaturia 12/1/2010 60 Male 168 lb 4/13/2011 Physician United Kingdom
Primary
Concomitant
Hypoxia Hospitalization 47 Male 5/6/2011 Physician United States
Primary
Concomitant
Injection Site Pain 9/2/2010 59 Female 5/10/2011 Pharmacist United States
Primary
Concomitant
Cardiac Arrest Hospitalization 47 Male 5/17/2011 Physician United States
Primary
Concomitant
Breath Sounds Abnormal Hospitalization 47 Male 5/23/2011 Other Health Professional United States
Primary
Concomitant
Intestinal Dilatation Other Serious 47 Male 6/3/2011 Physician United States
Primary
Secondary
Granulocytopenia Other Serious 4/4/2011 53 Female 184 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Muscle Contracture Other Serious Female 7/2/2011 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Death Female 7/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypoaesthesia Hospitalization 5/10/2010 56 Female 157 lb 7/11/2011 Consumer Brazil
Primary
Concomitant
Febrile Neutropenia Hospitalization 8/1/2009 33 Female 96 lb 7/18/2011 Physician Brazil
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious Female 272 lb 7/19/2011 United States
Primary
Concomitant
Haematoma Other Serious 6/1/2011 68 Female 7/25/2011 Other Health Professional United States
Primary
Concomitant
Bowel Movement Irregularity Hospitalization 9/14/2011 67 Male 243 lb 9/20/2011 Consumer Brazil
Primary
Concomitant
Somnolence Hospitalization 9/14/2011 67 Male 243 lb 9/22/2011 Consumer Brazil
Primary
Concomitant
Somnolence Hospitalization 9/14/2011 67 Male 243 lb 9/30/2011 Consumer Brazil
Primary
Concomitant
Injection Site Reaction 11/2/2010 59 Female 10/28/2011 Consumer United States
Primary
Concomitant
Myocardial Infarction Death 10/10/2011 58 Male 10/31/2011 Physician United States
Primary
Concomitant
Muscular Weakness Other Serious 1/1/2011 Female 11/14/2011 Consumer Germany
Primary
Concomitant
Impaired Healing Hospitalization 10/6/2010 66 Male 220 lb 11/23/2011 Germany
Primary
Secondary
Concomitant
Wound Infection Hospitalization 7/21/2010 65 Male 234 lb 11/24/2011 Physician Germany
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 10/25/2011 77 Female 121 lb 11/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Death 10/10/2011 58 Male 12/19/2011 Physician United States
Primary
Concomitant
Neutropenia Hospitalization 10/25/2011 77 Female 121 lb 12/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nausea Other Serious 1/1/2009 61 Male 265 lb 1/6/2012 Consumer United States
Primary
Concomitant
Contusion Other Serious 12/31/2010 56 Female 155 lb 1/13/2012 Consumer United States
Primary
Concomitant
Haemoglobin Decreased Death 10/25/2011 77 Female 121 lb 1/9/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Joint Swelling Other Serious 12/24/2010 56 Female 154 lb 1/27/2012 Physician United States
Primary
Secondary
Concomitant
Weight Increased 9/1/2010 67 Female 1/27/2012 Consumer United States
Primary
Concomitant
Injection Site Erythema Female 1/28/2012 Consumer United States
Primary
Concomitant
Dizziness 4/1/2011 84 Female 150 lb 1/28/2012 Consumer United States
Primary
Concomitant
Impaired Healing 4/15/2011 67 Female 1/28/2012 Consumer United States
Primary
Concomitant
Abdominal Pain 5/1/2011 74 Female 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Pain 9/30/2011 58 Female 1/28/2012 Consumer United States
Primary
Concomitant
Angioedema Other Serious 12/30/2011 64 Female 164 lb 1/19/2012 Pharmacist United States
Primary
Concomitant
Memory Impairment Other Serious 12/24/2010 56 Female 154 lb 2/9/2012 Physician United States
Primary
Secondary
Concomitant
Blood Uric Acid Increased 55 Female 2/10/2012 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 1/6/2012 72 Male 223 lb 2/10/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 1/6/2012 72 Male 2/15/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2012 67 Female 2/17/2012 Consumer United States
Primary
Concomitant
Diarrhoea Other Serious 1/1/2009 61 Male 265 lb 2/20/2012 Consumer United States
Primary
Concomitant
Gait Disturbance Other Serious 1/1/2011 73 Female 123 lb 2/27/2012 Consumer Germany
Primary
Concomitant
Pneumonia Hospitalization 10/25/2011 77 Female 55 lb 2/21/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Flank Pain 7/25/2011 74 Female 160 lb 12/20/2011 Consumer United States
Primary
Concomitant
Sinusitis Other Serious 12/25/2011 55 Male 236 lb 3/1/2012 Consumer United States
Primary
Concomitant
Death Death 70 Male 2/27/2012 Consumer United States
Primary
Concomitant
Extranodal Marginal Zone B-cell Lymphoma (Malt Type) Hospitalization 1/1/2010 68 Female 3/6/2012 Other Health Professional United States
Primary
Concomitant
Visual Impairment Other Serious Male 131 lb 3/25/2012 Consumer United States
Primary
Concomitant
Abdominal Pain Upper Other Serious 1/1/2007 50 Female 3/27/2012 Consumer Brazil
Primary
Concomitant
Depression Other Serious 1/1/2007 50 Female 3/27/2012 Other Health Professional Brazil
Primary
Concomitant
Lipoma Other Serious 2/7/2012 69 Male 4/2/2012 Other Health Professional United Kingdom
Primary
Concomitant
Hypertension 72 Female 4/9/2012 Consumer Brazil
Primary
Concomitant
C-reactive Protein Increased Death 1/1/2012 63 Male 226 lb 4/16/2012 Physician United States
Primary
Concomitant
Meningioma Other Serious 1/1/2010 68 Female 4/20/2012 Physician United States
Primary
Concomitant
Demyelinating Polyneuropathy Disability 9/1/2011 58 Female 4/24/2012 Physician United Kingdom
Primary
Concomitant
Rash Generalised Hospitalization 4/3/2012 83 Female 143 lb 5/3/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Disability 9/1/2011 58 Female 5/18/2012 Consumer United Kingdom
Primary
Concomitant
Menopause Other Serious 1/1/2007 50 Female 6/1/2012 Consumer Brazil
Primary
Concomitant
Cardiac Disorder Other Serious Male 6/1/2012 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2011 75 Female 157 lb 6/15/2012 Consumer United States
Primary
Concomitant
Breath Sounds Abnormal Disability Female 226 lb 6/8/2012 Lawyer United States
Primary
Concomitant
Breast Cancer Other Serious 1/1/2012 64 Female 6/20/2012 Other Health Professional United States
Primary
Concomitant
Demyelinating Polyneuropathy Disability 9/1/2011 58 Female 6/26/2012 Consumer United Kingdom
Primary
Concomitant
Weight Increased Other Serious 1/1/2010 55 Female 174 lb 6/27/2012 Consumer Brazil
Primary
Concomitant
Stomatitis Other Serious 1/1/2010 53 Female 7/9/2012 Consumer United States
Primary
Concomitant
Blood Creatine Phosphokinase Increased Other Serious 6/1/2012 66 Male 403 lb 7/26/2012 Physician Germany
Primary
Concomitant
Drug Dose Omission Female 260 lb 7/27/2012 Consumer United States
Primary
Concomitant
Skin Necrosis Hospitalization 6/24/2012 76 Female 7/31/2012 Pharmacist United Kingdom
Primary
Concomitant
Bone Pain Male 185 lb 8/3/2012 Consumer United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 7/16/2012 59 Female 184 lb 8/10/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 10/11/2011 81 Male 154 lb 8/13/2012 Physician United Kingdom
Primary
Concomitant
Drug Interaction Hospitalization 7/16/2012 59 Female 8/16/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 7/16/2012 59 Female 184 lb 8/20/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 7/16/2012 59 Female 184 lb 8/20/2012 Physician United Kingdom
Primary
Secondary
Concomitant

Drug Data