Simvastatin combined with Synthroid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Dizziness Hospitalization 6/24/2004 57 Male 1/3/2006 Pharmacist United States
Primary
Secondary
Concomitant
Dizziness Hospitalization 6/24/2004 57 Male 1/4/2006 Pharmacist United States
Primary
Secondary
Concomitant
Palpitations Other Serious 11/18/2005 63 Female 149 lb 1/9/2006 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 8/5/2005 75 Male 1/19/2006 United States
Primary
Concomitant
Haemorrhagic Stroke Hospitalization 11/23/2005 81 Male 172 lb 11/23/2005 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/1/2005 82 Male 172 lb 11/1/2005 Pharmacist United States
Primary
Concomitant
Balance Disorder Other Serious 10/1/2005 84 Female 130 lb 1/20/2006 United States
Primary
Concomitant
Renal Failure Other Serious 1/13/2004 Female 157 lb 3/17/2006 Canada
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/27/2005 76 Female 3/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Cough Other Serious 1/31/2006 74 Male 256 lb 2/10/2006 Pharmacist United States
Primary
Concomitant
Scleral Discolouration Other Serious 9/12/2005 Male 221 lb 3/31/2006 Pharmacist United States
Primary
Concomitant
Tachycardia Hospitalization 4/13/2006 43 Male 192 lb 4/13/2006 Pharmacist United States
Primary
Concomitant
Wound Drainage Hospitalization 4/17/2006 70 Male 178 lb 4/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pallor Hospitalization 1/1/1999 67 Male 247 lb 4/21/2006 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 3/1/2006 74 Male 263 lb 3/23/2006 Pharmacist United States
Primary
Concomitant
Haemorrhage Hospitalization 1/5/2006 67 Male 191 lb 5/8/2006 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/1999 67 Male 247 lb 5/15/2006 Lawyer United States
Primary
Concomitant
Renal Failure Other Serious 1/13/2004 Female 157 lb 5/12/2006 Canada
Primary
Secondary
Concomitant
Oedema Other Serious 3/13/2006 80 Male 162 lb 5/17/2006 Physician Canada
Primary
Concomitant
Respiratory Failure Death Female 138 lb 5/19/2006 Physician United States
Primary
Concomitant
Initial Insomnia 1/4/2006 71 Female 140 lb 4/3/2006 Consumer United States
Primary
Concomitant
Renal Failure Required Intervention 1/11/2006 76 Male 118 lb 5/24/2006 Pharmacist United States
Primary
Concomitant
Middle Insomnia 12/19/2005 84 Female 4/3/2006 Consumer United States
Primary
Concomitant
Blood Creatine Phosphokinase Increased Required Intervention 6/6/2006 82 Male 204 lb 6/7/2006 Pharmacist United States
Primary
Concomitant
Balance Disorder Other Serious 10/1/2005 84 Female 130 lb 4/20/2006 Physician United States
Primary
Concomitant
Muscle Spasms 3/31/2006 Male 212 lb 6/29/2006 Pharmacist United States
Primary
Concomitant
Muscle Spasms 3/28/2006 Male 272 lb 6/28/2006 Pharmacist United States
Primary
Concomitant
Rash Hospitalization 5/29/2006 81 Male 243 lb 7/14/2006 Pharmacist United States
Primary
Concomitant
Pain In Extremity Hospitalization 12/7/2005 75 Male 190 lb 5/8/2006 United States
Primary
Concomitant
Pollakiuria 73 Female 6/19/2006 Consumer United States
Primary
Concomitant
Heart Rate Irregular Hospitalization 5/21/2006 64 Male 224 lb 5/23/2006 Pharmacist United States
Primary
Concomitant
Insomnia 4/1/2006 67 Female 230 lb 7/12/2006 Consumer United States
Primary
Concomitant
Pneumonia 1/1/2006 54 Female 166 lb 7/12/2006 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 75 Male 128 lb 8/1/2006 Consumer United States
Primary
Concomitant
Arthralgia 3/1/2006 77 Male 180 lb 7/12/2006 Consumer United States
Primary
Secondary
Concomitant
Middle Insomnia 3/1/2006 78 Female 200 lb 7/12/2006 Consumer United States
Primary
Concomitant
Petit Mal Epilepsy Hospitalization 8/19/2006 54 Male 8/29/2006 Consumer United States
Primary
Concomitant
Hyperhidrosis 5/31/2006 62 Male 284 lb 7/19/2006 Consumer United States
Primary
Concomitant
Drug Interaction Potentiation Death 2/24/2006 85 Female 9/14/2006 Physician United States
Primary
Concomitant
Interacting
Dizziness Male 408 lb 9/20/2006 Pharmacist United States
Primary
Concomitant
Oedema Peripheral Hospitalization 8/1/2006 56 Male 9/25/2006 Consumer United States
Primary
Concomitant
Hypersensitivity Hospitalization 67 Male 7/10/2006 United States
Primary
Concomitant
Rash Other Serious 1/1/2002 Female 140 lb 10/13/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Required Intervention 8/7/2006 88 Male 169 lb 9/20/2006 Pharmacist United States
Primary
Concomitant
Oedema Peripheral Hospitalization 8/1/2006 56 Male 134 lb 10/25/2006 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 1/13/2004 Female 157 lb 11/1/2006 Canada
Primary
Secondary
Concomitant
Muscular Weakness 79 Female United States
Primary
Concomitant
Pharmaceutical Product Complaint Hospitalization 10/5/2006 82 Male 11/24/2006 Consumer United States
Primary
Concomitant
Thyroid Cancer Hospitalization 12/14/2006 82 Male 177 lb 1/4/2007 Physician United States
Primary
Concomitant
Insomnia 1/1/2006 37 Female 250 lb 10/11/2006 Consumer United States
Primary
Concomitant
Dysgeusia 6/1/2006 82 Female 118 lb 10/11/2006 Consumer United States
Primary
Concomitant
Mental Status Changes Required Intervention 1/8/2007 57 Male 153 lb 1/8/2007 Pharmacist United States
Primary
Concomitant
Pharyngolaryngeal Pain Other Serious 7/1/2006 70 Female 1/9/2007 Consumer United States
Primary
Concomitant
Blood Creatine Increased Hospitalization 1/16/2007 74 Male 1/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Cough Other Serious 1/5/2007 79 Male 165 lb 1/5/2007 Pharmacist United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 11/15/2006 60 Male 335 lb 12/19/2006 Pharmacist United States
Primary
Concomitant
Myocardial Ischaemia Other Serious 10/1/2006 82 Male 2/12/2007 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/5/2006 Male 191 lb 3/5/2007 United States
Primary
Concomitant
Diarrhoea Other Serious 12/28/2006 75 Male 140 lb 1/31/2007 Pharmacist United States
Primary
Concomitant
Paraesthesia 7/1/2006 Male 1/12/2007 Consumer United States
Primary
Secondary
Concomitant
Insomnia 10/10/2006 83 Female 125 lb 1/12/2007 Consumer United States
Primary
Concomitant
Insomnia 11/15/2006 74 Female 137 lb 1/12/2007 Consumer United States
Primary
Concomitant
Paradoxical Drug Reaction 9/25/2006 72 Female 150 lb 1/12/2007 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 241 lb 4/11/2007 Consumer United States
Primary
Concomitant
Throat Tightness 10/1/2006 67 Female 1/12/2007 Consumer United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 3/1/2007 78 Female 4/21/2007 United States
Primary
Concomitant
Oral Pain Required Intervention 1/22/2007 76 Male 190 lb 2/7/2007 Physician United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 9/16/2006 75 Male 222 lb 4/25/2007 Consumer United States
Primary
Concomitant
Delirium Hospitalization 1/16/2007 89 Male 240 lb 1/17/2007 Pharmacist United States
Primary
Concomitant
Treatment Failure Other Serious 6/10/2006 79 Female 107 lb 5/7/2007 Physician
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 7/4/2006 78 Female 5/8/2007 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 5/1/2007 52 Female 135 lb 5/30/2007 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 10/15/2006 71 Female 154 lb 1/14/2007 Pharmacist United States
Primary
Concomitant
Dysgeusia 3/13/2007 75 Female 152 lb 4/12/2007 Consumer United States
Primary
Concomitant
Dysgeusia 1/25/2007 70 Female 168 lb 4/12/2007 Consumer United States
Primary
Concomitant
Suicidal Ideation 1/1/2007 72 Female 157 lb 4/12/2007 Physician United States
Primary
Concomitant
Syncope Hospitalization 6/16/2004 82 Male 3/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 7/4/2006 78 Female 107 lb 5/30/2007 Consumer United States
Primary
Secondary
Concomitant
Malaise Other Serious 1/1/2004 Female 6/8/2007 Consumer Brazil
Primary
Secondary
Concomitant
Macular Oedema Other Serious 74 Female 6/11/2007 Consumer Canada
Primary
Concomitant
Thrombocytopenic Purpura Other Serious 1/1/2007 79 Female 146 lb 6/5/2007 Pharmacist United States
Primary
Concomitant
Hepatic Enzyme Increased 12/12/2006 70 Female 5/17/2007 United States
Primary
Concomitant
Hypersensitivity 10/1/2006 67 Female 4/10/2007 Physician United States
Primary
Concomitant
Back Pain 75 Female 130 lb 6/25/2007 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 65 Female 7/11/2007 Consumer United States
Primary
Concomitant
Nausea 9/1/2006 Female 7/26/2007 Consumer United States
Primary
Concomitant
Insomnia 5/27/2007 73 Female 170 lb 7/10/2007 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 65 Female 8/8/2007 Consumer United States
Primary
Concomitant
Wheezing Other Serious 12/20/2006 Male 190 lb 8/8/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 65 Female 9/4/2007 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 Female 181 lb 9/10/2007 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 2/1/2005 Female 9/13/2007 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 65 Female 276 lb 9/20/2007 Consumer United States
Primary
Concomitant
Wound Secretion Other Serious 8/13/2007 60 Female 200 lb 9/17/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 8/1/2006 Female 187 lb 9/25/2007 Physician United States
Primary
Concomitant
Hepatic Steatosis 12/1/2006 70 Female 8/16/2007 Other Health Professional United States
Primary
Concomitant
Gastric Haemorrhage Other Serious Female 9/25/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Medical Device Complication Hospitalization 9/27/2007 66 Male 121 lb 10/1/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 251 lb 10/5/2007 Physician United States
Primary
Concomitant
Eye Operation Other Serious 9/1/2007 61 Female 10/8/2007 Consumer Canada
Primary
Concomitant
Interacting
Dry Mouth 6/26/2007 72 Female 9/21/2007 Consumer United States
Primary
Concomitant
Thrombocytopenia 10/15/2007 Other Health Professional United States
Primary
Concomitant
Uterine Leiomyoma Hospitalization 7/1/2007 80 Female 119 lb 10/24/2007 Consumer United States
Primary
Secondary
Concomitant
Rash Other Serious 1/1/2007 73 Female 122 lb 11/2/2007 Consumer United States
Primary
Concomitant
Cough 4/1/2007 77 Male 11/13/2007 Consumer United States
Primary
Concomitant
Throat Tightness Other Serious Female 11/20/2007 Other Health Professional United States
Primary
Concomitant
Overdose 8/20/2007 50 Female 174 lb 11/16/2007 Physician United States
Primary
Concomitant
Food Allergy Other Serious 11/14/2007 Female 11/30/2007 Physician United States
Primary
Concomitant
Incorrect Dose Administered Other Serious 2/12/2007 55 Male 158 lb 11/14/2007 Consumer United States
Primary
Concomitant
Malaise Other Serious 64 Female 141 lb 12/14/2007 Consumer
Primary
Secondary
Concomitant
Pruritus 10/12/2007 80 Male 12/27/2007 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 8/1/2006 Female 187 lb 12/28/2007 Physician United States
Primary
Concomitant
Erectile Dysfunction 9/1/2007 64 Male 1/2/2008 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 12/26/2007 70 Female 137 lb 1/17/2008 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia 1/16/2008 65 Male 238 lb 1/23/2008 United States
Primary
Concomitant
Hypersensitivity Other Serious 11/14/2007 Female 1/21/2008 Physician United States
Primary
Concomitant
Myalgia Other Serious 12/21/2007 75 Male 238 lb 1/24/2008 Physician United States
Primary
Concomitant
Weight Increased Other Serious 12/1/2007 70 Female 137 lb 1/29/2008 Physician United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint 5/17/2007 61 Female 2/5/2008 Consumer United States
Primary
Concomitant
Visual Disturbance Other Serious 1/31/2008 78 Male 155 lb 2/11/2008 Consumer United States
Primary
Concomitant
Uterine Polyp Other Serious 1/1/2008 Female 2/20/2008 Physician United States
Primary
Concomitant
Thrombocytopenia 1/16/2008 65 Male 238 lb 2/27/2008 Pharmacist United States
Primary
Concomitant
Drug Ineffective Other Serious 2/17/2008 70 Male 220 lb 2/26/2008 Consumer Brazil
Primary
Concomitant
Muscle Spasms 1/1/2008 74 Female 117 lb 3/6/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/31/2008 78 Male 155 lb 3/5/2008 Consumer United States
Primary
Concomitant
Malignant Neoplasm Progression Death 12/23/2007 62 Male 3/24/2008 Physician United States
Primary
Concomitant
Ocular Vascular Disorder Other Serious 3/20/2008 Female 3/28/2008 Consumer United States
Primary
Concomitant
Thinking Abnormal Disability 2/4/2008 Female 126 lb 4/7/2008 Consumer United States
Primary
Concomitant
Self-injurious Ideation Other Serious Male 193 lb 4/10/2008 United States
Primary
Concomitant
Tremor 12/1/2007 63 Female 185 lb 4/4/2008 United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2005 Female 136 lb 4/10/2008 Physician United States
Primary
Concomitant
Eye Pain Other Serious 2/21/2008 Female 301 lb 4/18/2008 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2007 74 Female 4/21/2008 Consumer United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 3/1/2008 Female 4/21/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 12/1/2007 70 Female 137 lb 4/24/2008 Physician United States
Primary
Secondary
Concomitant
Dysphagia 9/1/2007 Female 4/28/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/31/2008 78 Male 155 lb 4/24/2008 Consumer United States
Primary
Concomitant
Thinking Abnormal Hospitalization 3/1/2008 Female 4/30/2008 Consumer United States
Primary
Concomitant
Visual Disturbance 4/1/2008 Male 5/7/2008 Physician Canada
Primary
Concomitant
Nausea Hospitalization Female 170 lb 4/27/2008 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/1/2005 Female 144 lb 5/15/2008 Physician United States
Primary
Concomitant
Hypotension Hospitalization 5/6/2008 82 Male 5/19/2008 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2005 Female 144 lb 5/22/2008 Physician United States
Primary
Concomitant
Musculoskeletal Discomfort 5/8/2008 72 Male 210 lb 5/30/2008 United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 12/1/2007 58 Male 6/6/2008 Consumer United States
Primary
Concomitant
Macular Degeneration Other Serious Female 6/9/2008 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2005 Female 143 lb 5/30/2008 Physician United States
Primary
Concomitant
Papillary Thyroid Cancer Hospitalization 12/14/2006 Male 177 lb 6/6/2008 Physician United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 6/1/2008 Male 220 lb 6/13/2008 Consumer Brazil
Primary
Concomitant
Headache 3/11/2008 79 Female 190 lb 6/16/2008 Consumer United States
Primary
Concomitant

Drug Data