Simvastatin combined with Vesicare

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased Other Serious 8/2/2006 82 Male 9/14/2006 Physician United Kingdom
Primary
Concomitant
Drug Ineffective 5/1/2006 73 Male 180 lb 9/12/2006 Physician United States
Primary
Secondary
Concomitant
Blood Pressure Increased 5/1/2006 73 Male 180 lb 6/1/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Incontinence 8/3/2006 60 Female 9/12/2006 United States
Primary
Concomitant
Urinary Incontinence 8/3/2006 60 Female 12/6/2006 United States
Primary
Concomitant
Muscle Spasms Other Serious 2/1/2007 59 Female 3/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sleep Paralysis Other Serious 3/29/2007 182 lb 5/4/2007 Consumer United Kingdom
Primary
Concomitant
Vision Blurred Disability 4/12/2007 71 Female 198 lb 5/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Therapeutic Response Unexpected 80 Male 6/18/2007 Consumer United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 1/1/2007 68 Female 152 lb 6/22/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 5/21/2007 68 Female 152 lb 6/29/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Dry Mouth 83 Female 9/21/2007 Consumer United States
Primary
Concomitant
Stomach Discomfort 81 Male 9/21/2007 Other Health Professional United States
Primary
Concomitant
Dry Mouth 6/26/2007 72 Female 9/21/2007 Consumer United States
Primary
Concomitant
Eczema 70 Female 9/21/2007 Other Health Professional United States
Primary
Concomitant
Diarrhoea 6/21/2007 80 Female 188 lb 9/21/2007 Physician United States
Primary
Concomitant
Dry Mouth 4/4/2007 82 Male 9/21/2007 Consumer United States
Primary
Concomitant
Pain In Extremity 85 Female 119 lb 12/21/2007 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 4/28/2007 74 Male 1/9/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/28/2007 74 Male 1/21/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Migraine Other Serious 1/1/2007 Male 220 lb 3/5/2008 Physician United States
Primary
Concomitant
Interacting
Visual Disturbance 11/8/2007 45 Female 2/4/2008 Physician United States
Primary
Concomitant
Nervousness Hospitalization 6/10/2008 80 Female 150 lb 6/25/2008 Consumer United States
Primary
Secondary
Concomitant
Nervousness Hospitalization 6/10/2008 80 Female 150 lb 7/28/2008 Consumer United States
Primary
Secondary
Concomitant
Musculoskeletal Chest Pain Other Serious 12/17/2007 71 Female 111 lb 8/4/2008 Consumer United States
Primary
Concomitant
Pleural Effusion Hospitalization 7/12/2008 Male 167 lb 9/9/2008 Japan
Primary
Secondary
Concomitant
Altered State Of Consciousness Hospitalization 7/12/2008 Male 167 lb 9/24/2008 Japan
Primary
Secondary
Concomitant
Drug Ineffective For Unapproved Indication 1/1/2006 70 Male 11/10/2008 Consumer
Primary
Concomitant
Wheezing 10/5/2008 67 Female 11/20/2008 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 2/17/2008 Female 12/3/2008 Consumer United States
Primary
Concomitant
Thalamic Infarction Hospitalization 3/1/2009 61 Male 4/9/2009 United States
Primary
Concomitant
Thalamic Infarction Hospitalization 3/1/2009 61 Male 4/10/2009 United States
Primary
Concomitant
Syncope Hospitalization 10/1/2008 87 Female 4/14/2009 Consumer Germany
Primary
Secondary
Concomitant
Application Site Pruritus Disability 9/1/2008 Female 4/22/2009 Pharmacist United States
Primary
Concomitant
Weight Decreased Required Intervention 8/11/2008 Male 172 lb 4/2/2009 Consumer United States
Primary
Concomitant
Thalamic Infarction Hospitalization 3/1/2009 61 Male 5/18/2009 United States
Primary
Concomitant
General Physical Health Deterioration Hospitalization 5/4/2009 Male 5/22/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Thalamic Infarction Hospitalization 3/1/2009 61 Male 5/27/2009 United States
Primary
Concomitant
General Physical Health Deterioration Hospitalization 5/4/2009 Male 5/28/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 4/30/2009 67 Female 6/1/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 4/30/2009 67 6/8/2009 Physician Japan
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 5/4/2009 Male 6/15/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 4/30/2009 67 Female 6/18/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Death 89 Female 6/21/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 7/1/2001 66 Female 190 lb 6/26/2009 Physician United States
Primary
Concomitant
Pollakiuria Disability 2/28/2009 57 Male 148 lb 6/30/2009 Physician United States
Primary
Concomitant
Pollakiuria Disability 2/28/2009 57 Male 148 lb 7/7/2009 Other Health Professional United States
Primary
Concomitant
Pain Death 89 Female 7/6/2009 United States
Primary
Concomitant
Pulmonary Oedema Other Serious 4/30/2009 67 7/20/2009 Physician Japan
Primary
Secondary
Concomitant
Flushing 1/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Visual Acuity Reduced 3/17/2009 Female 8/22/2009 United States
Primary
Concomitant
Urinary Tract Infection Death 89 Female 9/3/2009 United States
Primary
Concomitant
Ventricular Tachyarrhythmia Hospitalization 7/17/2009 80 Female 9/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rash Generalised Other Serious 9/1/2009 41 Female 132 lb 9/11/2009 Consumer United States
Primary
Concomitant
Rash Erythematous Other Serious 9/1/2009 41 Female 132 lb 9/11/2009 Consumer United States
Primary
Concomitant
Urinary Tract Infection Death 89 Female 9/22/2009 United States
Primary
Concomitant
Urinary Tract Infection Death 89 Female 10/10/2009 United States
Primary
Concomitant
Urinary Tract Infection Death 89 Female 10/16/2009 United States
Primary
Concomitant
Urinary Tract Infection Enterococcal Hospitalization 89 Female 11/9/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 71 Female 78 lb 11/9/2009 Norway
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 71 Female 11/12/2009 Other Health Professional Norway
Primary
Secondary
Concomitant
Urinary Tract Infection Enterococcal Hospitalization 89 Female 11/16/2009 United States
Primary
Concomitant
Stomatitis Hospitalization 7/15/2009 80 Male 168 lb 8/31/2009 Pharmacist United States
Primary
Concomitant
Unevaluable Event Hospitalization 11/6/2009 Female 12/10/2009 Consumer United States
Primary
Concomitant
Vaginal Infection Other Serious 1/1/2009 62 Female 12/11/2009 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Enterococcal Hospitalization 89 Female 12/14/2009 Consumer United States
Primary
Concomitant
Loss Of Consciousness Other Serious 9/1/2009 Female 155 lb 12/30/2009 United States
Primary
Concomitant
Fatigue Hospitalization 62 Female 132 lb 12/22/2009 Other Health Professional United States
Primary
Concomitant
Vaginal Infection Other Serious 1/1/2009 62 Female 1/7/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 9/7/2009 Female 1/6/2010 Physician Germany
Primary
Concomitant
Pain Hospitalization 9/1/2009 Female 1/15/2010 Consumer United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 89 Female 1/20/2010 United States
Primary
Concomitant
Injection Site Pain 11/1/2008 Female 175 lb 1/30/2010 Consumer United States
Primary
Concomitant
General Physical Health Deterioration Hospitalization 5/4/2009 Male 190 lb 2/10/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 12/15/2009 58 Male 181 lb 2/18/2010 Physician United Kingdom
Primary
Concomitant
White Blood Cells Urine Positive Hospitalization 89 Female 2/19/2010 United States
Primary
Concomitant
Oesophageal Spasm Hospitalization 61 Female 3/5/2010 Consumer United States
Primary
Concomitant
Visual Impairment Other Serious 1/12/2010 69 Female 107 lb 3/8/2010 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2009 Female 135 lb 3/17/2010 United States
Primary
Concomitant
Pulmonary Fibrosis Death Male 3/24/2010 Consumer United States
Primary
Concomitant
Respiratory Failure Death Male 139 lb 3/30/2010 Physician United States
Primary
Concomitant
Underdose Other Serious 68 Female 4/8/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 12/1/2009 66 Female 4/6/2010 Consumer United States
Primary
Concomitant
Incisional Hernia Other Serious 2/1/2010 64 Female 4/13/2010 Physician United States
Primary
Concomitant
Swelling Face Other Serious 2/1/2010 Female 4/20/2010 Consumer United States
Primary
Concomitant
Glycosylated Haemoglobin Increased Other Serious Male 4/26/2010 Sweden
Primary
Concomitant
Swelling Face Other Serious 2/1/2010 Female 5/17/2010 Consumer United States
Primary
Concomitant
Pain Hospitalization 9/1/2009 Female 5/20/2010 Physician United States
Primary
Secondary
Concomitant
Headache 4/15/2010 64 Female 140 lb 5/21/2010 Consumer United States
Primary
Concomitant
Nausea 3/4/2010 76 Male 174 lb 5/27/2010 Consumer United States
Primary
Concomitant
Urinary Incontinence Other Serious 10/1/2009 80 Female 135 lb 6/7/2010 Other Health Professional United States
Primary
Concomitant
Underdose Other Serious 68 Female 6/25/2010 Consumer United States
Primary
Concomitant
Parosmia 1/1/2004 78 Female 180 lb 6/29/2010 Consumer United States
Primary
Concomitant
Paranoia Other Serious 1/1/2009 54 Female 230 lb 5/18/2010 United States
Primary
Concomitant
Pneumonitis Life Threatening 5/1/2010 Female 125 lb 8/3/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pain 4/1/2008 79 Male 195 lb 8/3/2010 Consumer United States
Primary
Concomitant
Tooth Loss 8/5/2010 Consumer United States
Primary
Concomitant
Tremor Hospitalization 6/11/2010 38 Female 123 lb 8/13/2010 Physician United States
Primary
Concomitant
Pruritus 6/1/2009 59 Male 270 lb 8/28/2010 Consumer United States
Primary
Concomitant
Myalgia Other Serious 58 Female 9/2/2010 Other Health Professional United Kingdom
Primary
Concomitant
Somnolence 11/1/2009 86 Female 132 lb 9/14/2010 Consumer United States
Primary
Concomitant
Pain Disability Female 113 lb 9/14/2010 Other Health Professional United States
Primary
Concomitant
Vaginal Haemorrhage 6/1/2009 47 Female 9/17/2010 Other Health Professional United States
Primary
Concomitant
Bradycardia Hospitalization 10/12/2008 87 Female 185 lb 9/23/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/1/2010 49 Female 359 lb 9/24/2010 Physician United States
Primary
Concomitant
Pain Hospitalization 8/6/2010 60 Female 170 lb 9/24/2010 Physician United States
Primary
Concomitant
Syncope Hospitalization 10/12/2008 87 Female 185 lb 10/1/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Hypotension Hospitalization 10/12/2008 87 Female 185 lb 10/7/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Bradycardia Hospitalization 10/12/2008 87 Female 185 lb 10/7/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 10/1/2008 87 Female 10/8/2010 Consumer Germany
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 8/6/2010 60 Female 170 lb 10/8/2010 Other Health Professional United States
Primary
Concomitant
Tremor Hospitalization 1/1/2007 38 Female 123 lb 10/21/2010 Other Health Professional United States
Primary
Concomitant
Death Death 10/25/2010 Physician United States
Primary
Concomitant
Bradycardia Hospitalization 10/12/2008 87 Female 185 lb 10/29/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Urticaria Other Serious 7/1/2010 61 Female 9/1/2010 Pharmacist United States
Primary
Concomitant
Nausea 3/4/2010 76 Male 174 lb 11/9/2010 Consumer United States
Primary
Concomitant
Abscess Hospitalization 6/30/2010 66 Female 240 lb 12/6/2010 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 3/1/2010 12/9/2010 United States
Primary
Concomitant
Product Quality Issue Other Serious 76 Female 12/1/2010 Pharmacist United States
Primary
Concomitant
Death Death 12/20/2010 Physician United States
Primary
Concomitant
Injection Site Haematoma 3/1/2010 67 Female 1/30/2011 Consumer United States
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 5/23/2010 83 Female 198 lb 2/4/2011 Physician Germany
Primary
Concomitant
Angle Closure Glaucoma Hospitalization 70 Female 195 lb 2/9/2011 Physician United Kingdom
Primary
Concomitant
Angle Closure Glaucoma Hospitalization 12/20/2010 70 Female 195 lb 2/11/2011 Physician United Kingdom
Primary
Concomitant
Oedema Peripheral Other Serious 12/6/2010 53 Female 284 lb 2/1/2011 Consumer United States
Primary
Concomitant
Death Death Male 2/21/2011 United States
Primary
Concomitant
Pain Other Serious 9/1/2009 42 Female 132 lb 2/25/2011 Physician United States
Primary
Concomitant
Delirium Other Serious 12/1/2010 84 Female 104 lb 3/22/2011 Physician France
Primary
Concomitant
Gastrointestinal Stromal Tumour Death Male 3/23/2011 Consumer United States
Primary
Concomitant
Erectile Dysfunction Hospitalization 46 Male 250 lb 3/22/2011 United States
Primary
Concomitant
Osteoporotic Fracture Other Serious Female 166 lb 4/15/2011 Consumer United States
Primary
Concomitant
Osteoporotic Fracture Other Serious 2/1/2011 76 Female 166 lb 4/18/2011 Consumer United States
Primary
Concomitant
Amnesia 2/1/2011 81 Male 4/21/2011 Consumer United States
Primary
Concomitant
Constipation 4/14/2011 64 Female 190 lb 4/19/2011 Consumer United States
Primary
Concomitant
Pollakiuria 1/1/2010 69 Male 150 lb 5/2/2011 Consumer United States
Primary
Secondary
Concomitant
Dry Mouth Other Serious 1/18/2011 75 Female 141 lb 5/9/2011 Consumer United Kingdom
Primary
Concomitant
Drug Dependence Other Serious Female 162 lb 6/3/2011 Consumer United States
Primary
Concomitant
Subcutaneous Haematoma Other Serious 5/1/2009 64 Male 6/7/2011 Physician Norway
Primary
Concomitant
Pollakiuria 1/1/2010 69 Male 150 lb 6/10/2011 Consumer United States
Primary
Secondary
Depressed Level Of Consciousness Hospitalization 3/31/2011 78 Male 6/14/2011 Other Health Professional Sweden
Primary
Secondary
Concomitant
Cholecystitis Acute Hospitalization Female 185 lb 6/16/2011 Physician United States
Primary
Concomitant
Gingival Infection Death 9/24/2010 49 Female 6/22/2011 Pharmacist United States
Primary
Concomitant
Hyperphagia Other Serious Female 162 lb 6/23/2011 Consumer United States
Primary
Concomitant
Hallucination Hospitalization 11/26/2010 84 Female 104 lb 6/29/2011 Physician France
Primary
Concomitant
Odynophagia 3/7/2011 76 Female 7/7/2011 Consumer United States
Primary
Concomitant
Confusional State Hospitalization 6/2/2011 60 Female 280 lb 7/11/2011 Consumer United States
Primary
Concomitant
Musculoskeletal Pain 6/5/2011 83 Male 7/12/2011 Consumer United States
Primary
Concomitant
Confusional State Female 280 lb 7/12/2011 Consumer United States
Primary
Concomitant
Injection Site Pain 10/1/2010 61 Male 223 lb 7/11/2011 Other Health Professional United States
Primary
Concomitant
Nausea Other Serious 5/24/2011 78 Female 7/26/2011 Physician United States
Primary
Concomitant

Drug Data