Alendronate Sodium combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Breast Cancer Stage Iii Hospitalization 9/19/2005 Female 1/5/2006 Other Health Professional United Kingdom
Primary
Concomitant
Lethargy Other Serious 12/27/2005 64 Female 253 lb 12/30/2005 Pharmacist United States
Primary
Concomitant
Syncope Hospitalization 11/10/2005 Female 2/21/2006 Pharmacist United States
Primary
Concomitant
Myalgia Hospitalization 11/18/2005 Male 2/21/2006 Pharmacist United States
Primary
Concomitant
Hypoglycaemia Other Serious 11/3/2005 77 Male 174 lb 12/7/2005 Pharmacist United States
Primary
Concomitant
Psychotic Disorder 10/19/2005 74 Male 160 lb 11/1/2005 Pharmacist United States
Primary
Secondary
Concomitant
Urticaria Other Serious 12/1/2004 70 Female 137 lb 12/21/2005 Consumer United States
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 4/1/2005 69 Male 134 lb 2/14/2006 Physician United Kingdom
Primary
Concomitant
Weight Decreased Life Threatening 11/1/2005 Male 4/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Surgery Hospitalization 1/1/2002 67 Male 176 lb 4/25/2006 Lawyer United States
Primary
Concomitant
Surgery Hospitalization 1/1/2002 65 Male 176 lb 5/1/2006 Physician United States
Primary
Concomitant
Lethargy Hospitalization 4/23/2006 77 Male 208 lb 5/15/2006 Pharmacist United States
Primary
Concomitant
Wrong Drug Administered Other Serious 7/1/2005 82 Female 110 lb 5/30/2006 Physician Australia
Primary
Concomitant
Ulcer Other Serious 12/5/2005 73 Male 194 lb 12/6/2005 Other Health Professional United States
Primary
Concomitant
Fall Hospitalization 5/22/2006 85 Female 6/29/2006 Other Health Professional United Kingdom
Primary
Concomitant
Chest Pain Hospitalization 4/10/2004 69 Female 7/6/2006 Consumer Italy
Primary
Concomitant
Angioneurotic Oedema Life Threatening 6/9/2006 72 Female 144 lb 6/14/2006 Other Health Professional United States
Primary
Concomitant
Clostridium Difficile Colitis Hospitalization 7/15/2006 57 Female 212 lb 7/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/15/2006 57 Female 212 lb 7/19/2006 Pharmacist United States
Primary
Concomitant
Therapy Non-responder Other Serious 4/1/2004 75 Female 7/20/2006 Israel
Primary
Secondary
Concomitant
Constipation Required Intervention 8/1/2006 80 Male 175 lb 8/2/2006 Pharmacist United States
Primary
Secondary
Concomitant
Poor Quality Drug Administered Other Serious 7/9/2006 77 Female 8/2/2006 United States
Primary
Concomitant
Vomiting Other Serious 7/15/2005 82 Female 110 lb 8/23/2006 Physician Australia
Primary
Concomitant
Transplant Rejection Hospitalization 4/17/2006 55 Male 261 lb 5/10/2006 Pharmacist United States
Primary
Concomitant
Pulse Abnormal Other Serious 71 Female 6/6/2006 United States
Primary
Concomitant
Retroperitoneal Haemorrhage Other Serious 9/17/2004 74 Female 141 lb 8/28/2006 Australia
Primary
Secondary
Concomitant
Wound Hospitalization 7/14/2006 Male 242 lb 8/25/2006 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/10/2005 85 Female 8/25/2006 United Kingdom
Primary
Secondary
Concomitant
Poor Quality Drug Administered Other Serious 7/9/2006 77 Female 8/28/2006 United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/10/2005 85 Female 8/28/2006 United Kingdom
Primary
Secondary
Concomitant
Sepsis Life Threatening 63 Female 8/29/2006 United Kingdom
Primary
Secondary
Concomitant
Vasculitis Other Serious 11/15/2005 Female 111 lb 9/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Ischaemia Death Female 126 lb 11/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 54 Female 11/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Milk-alkali Syndrome Hospitalization 37 Female 11/29/2006
Primary
Secondary
Concomitant
Venous Pressure Jugular Increased Other Serious Female 142 lb 11/30/2006 Physician United Kingdom
Primary
Concomitant
Myalgia Hospitalization 1/1/2006 76 Female 12/27/2006 Physician France
Primary
Concomitant
Milk-alkali Syndrome Hospitalization 37 Female 12/28/2006
Primary
Secondary
Concomitant
Myalgia Hospitalization 1/1/2006 76 Female 1/4/2007 Physician France
Primary
Concomitant
Renal Impairment Hospitalization 11/8/2006 75 Male 1/8/2007
Primary
Secondary
Concomitant
Pneumonia Other Serious 7/5/2006 152 lb 1/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Venous Pressure Jugular Increased Other Serious 3/15/2006 Female 142 lb 1/24/2007 Physician United Kingdom
Primary
Concomitant
Treatment Noncompliance Hospitalization 10/6/2006 77 Male 123 lb 12/12/2006 Pharmacist United States
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Other Serious 7/5/2006 152 lb 2/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Plasma Cells Increased Other Serious 12/1/2006 74 Male 2/13/2007 Physician United States
Primary
Secondary
Concomitant
Plasma Cells Increased Other Serious 12/1/2006 74 Male 2/28/2007 Physician United States
Primary
Secondary
Concomitant
Malaise Hospitalization 9/15/2006 56 Female 4/25/2007 Consumer Australia
Primary
Concomitant
Tetany Other Serious 37 Female 4/26/2007 Other Health Professional United States
Primary
Concomitant
Tetany Other Serious 37 Female 4/26/2007 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 3/15/2007 70 Female 4/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 3/15/2007 70 Female 5/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 12/5/2006 Female 269 lb 5/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 54 Female 5/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Venous Pressure Jugular Increased Other Serious 3/15/2006 Female 146 lb 6/14/2007 Physician United Kingdom
Primary
Concomitant
Venous Pressure Jugular Increased Other Serious 3/15/2006 Female 146 lb 6/19/2007 Physician United Kingdom
Primary
Concomitant
Breast Cancer Stage Iii Hospitalization 9/19/2005 Female 212 lb 6/22/2007 Physician United Kingdom
Primary
Concomitant
Abdominal Distension 65 Male 6/29/2007 Pharmacist United States
Primary
Concomitant
Sepsis Hospitalization 6/11/2007 Male 101 lb 7/13/2007 Physician United Kingdom
Primary
Concomitant
Treatment Noncompliance Death 6/2/2007 7/13/2007 United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 7/5/2006 Male 152 lb 7/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Incision Site Infection Hospitalization Female 130 lb 7/23/2007 Canada
Primary
Concomitant
Oesophagitis 5/22/2007 73 Male 7/19/2007 Pharmacist United States
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 11/15/2006 Female 269 lb 7/27/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Musculoskeletal Chest Pain Hospitalization 12/5/2006 Female 269 lb 7/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vasculitis Other Serious 11/15/2005 Female 111 lb 8/6/2007 Physician United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 4/18/2007 Female 168 lb 8/24/2007 Physician Germany
Primary
Concomitant
Urinary Tract Infection Enterococcal Hospitalization 4/19/2007 Female 154 lb 8/24/2007 Physician Germany
Primary
Concomitant
Rib Fracture Hospitalization 7/18/2007 76 Female 238 lb 8/31/2007 Consumer United Kingdom
Primary
Concomitant
Fall Hospitalization 7/18/2007 76 Female 238 lb 9/6/2007 Consumer United Kingdom
Primary
Concomitant
Myocardial Infarction Life Threatening 8/21/2007 84 Male 119 lb 9/14/2007 Physician Australia
Primary
Concomitant
Fall Hospitalization 7/18/2007 76 Female 238 lb 9/18/2007 Physician United Kingdom
Primary
Concomitant
Blood Glucose Decreased Hospitalization 4/15/2007 75 Male 8/22/2007 Consumer United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 8/29/2007 52 Female 321 lb 9/26/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pleurisy Hospitalization 5/9/2007 Male 214 lb 10/11/2007 United Kingdom
Primary
Concomitant
Fall Hospitalization 7/18/2007 76 Female 238 lb 10/12/2007 Physician United Kingdom
Primary
Concomitant
Death Death Female 112 lb 10/31/2007 Physician Australia
Primary
Concomitant
Nodal Marginal Zone B-cell Lymphoma Other Serious 10/15/2007 Female 152 lb 11/7/2007 United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 8/15/2007 Male 196 lb 11/21/2007 United Kingdom
Primary
Concomitant
Skin Hyperpigmentation Other Serious 9/30/2007 70 Female 183 lb 12/11/2007 Physician Israel
Primary
Concomitant
Joint Swelling 8/19/2007 Male 165 lb 12/14/2007 United States
Primary
Concomitant
Nausea 9/1/2007 Female 150 lb 12/14/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/10/2004 52 Female 134 lb 1/16/2008 Other Health Professional United States
Primary
Concomitant
Respiratory Tract Infection Viral Other Serious 12/15/2007 75 Female 129 lb 1/24/2008 Greece
Primary
Concomitant
Respiratory Tract Infection Viral Other Serious 12/15/2007 75 Female 129 lb 2/1/2008 Greece
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2006 66 Female 150 lb 11/30/2007 Consumer United States
Primary
Secondary
Concomitant
Rash Hospitalization 7/1/2004 77 Female 127 lb 11/29/2007 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2003 60 Male 290 lb 11/29/2007 Consumer United States
Primary
Concomitant
Respiratory Tract Infection Viral Other Serious 12/15/2007 75 Female 129 lb 2/22/2008 Greece
Primary
Concomitant
Torsade De Pointes Hospitalization 2/8/2008 79 Female 3/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Tract Infection Viral Other Serious 12/15/2007 75 Female 129 lb 4/10/2008 Greece
Primary
Concomitant
Nodal Marginal Zone B-cell Lymphoma Other Serious 10/15/2007 Female 152 lb 5/2/2008 United States
Primary
Concomitant
Hypoglycaemia Hospitalization 3/25/2008 75 Female 5/16/2008 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/1/2008 Male 6/6/2008 Other Health Professional United Kingdom
Primary
Concomitant
Sinusitis 12/1/2007 Female 138 lb 6/13/2008 Consumer United States
Primary
Concomitant
Ischaemic Stroke Life Threatening 5/29/2008 73 Female 6/19/2008 Physician
Primary
Concomitant
Urinary Incontinence Other Serious 6/2/2000 51 Female 6/18/2008 United Kingdom
Primary
Concomitant
Hypoglycaemia Hospitalization 3/25/2008 75 Female 6/26/2008 Physician Japan
Primary
Secondary
Concomitant
Gallbladder Cancer Life Threatening 4/30/2008 Male 192 lb 6/27/2008 Physician United Kingdom
Primary
Concomitant
Syncope Hospitalization 3/30/2008 80 Male 7/23/2008 New Zealand
Primary
Concomitant
Metastases To Liver Other Serious 3/28/2008 Female 123 lb 8/7/2008 Physician United Kingdom
Primary
Concomitant
Oedema Peripheral 4/1/2008 69 Female 148 lb 7/30/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 6/13/2008 75 Female 8/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Flushing 2/1/2007 Female 95 lb 8/27/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 3/30/2008 80 Male 8/14/2008 New Zealand
Primary
Concomitant
Rheumatoid Arthritis 1/1/2008 Male 170 lb 9/12/2008 Consumer United States
Primary
Concomitant
Myalgia Other Serious 8/23/2008 87 Female 9/19/2008 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Hospitalization 5/1/2008 67 Female 9/29/2008 Physician France
Primary
Concomitant
Duodenal Ulcer Perforation Death 3/16/2008 71 Female 10/3/2008 United Kingdom
Primary
Concomitant
Visual Impairment Female 195 lb 10/19/2008 United States
Primary
Concomitant
Respiratory Distress Life Threatening 2/15/2008 61 Female 10/21/2008 Pharmacist United States
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Other Serious 10/20/2008 Female 176 lb 10/24/2008 Netherlands
Primary
Concomitant
Pneumonia Hospitalization 9/6/2008 Male 10/28/2008 Australia
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/11/2008 71 Female 10/27/2008 Consumer United Kingdom
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 9/8/2008 Female 176 lb 10/31/2008 Netherlands
Primary
Concomitant
Intestinal Obstruction Other Serious 11/6/2008 Other Health Professional United States
Primary
Secondary
Somnolence Other Serious 9/26/2008 Male 165 lb 11/7/2008 Physician United Kingdom
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 9/8/2008 Female 176 lb 11/13/2008 Netherlands
Primary
Concomitant
Scleritis Disability 89 Female 11/11/2008 United Kingdom
Primary
Concomitant
Palpitations Other Serious 10/9/2008 Female 172 lb 11/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 9/30/2008 Male 163 lb 11/24/2008 Australia
Primary
Secondary
Concomitant
Somnolence Other Serious 9/26/2008 Male 165 lb 12/5/2008 Pharmacist United Kingdom
Primary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 10/21/2008 86 Female 11/28/2008 United Kingdom
Primary
Secondary
Concomitant
Thoracic Vertebral Fracture Other Serious 4/1/2008 Female 180 lb 12/10/2008 United States
Primary
Concomitant
Accidental Exposure 10/1/2008 Female 12/12/2008 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection 11/1/2005 Female 12/12/2008 Consumer United States
Primary
Concomitant
Tremor Other Serious 10/1/2008 Female 148 lb 12/15/2008 Consumer Brazil
Primary
Concomitant
Oesophagitis Hospitalization 11/6/2008 70 Female 12/12/2008 United Kingdom
Primary
Concomitant
Oesophagitis Other Serious 10/1/2008 77 Female 1/27/2009 United Kingdom
Primary
Concomitant
Atrial Fibrillation Life Threatening 10/1/2007 65 Female 1/27/2009 United Kingdom
Primary
Concomitant
Depression Other Serious 11/4/2008 70 Female 2/12/2009 United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 1/16/2009 86 Male 202 lb 2/13/2009 Pharmacist United States
Primary
Secondary
Concomitant
Atrial Fibrillation Required Intervention 5/7/2008 85 Male 175 lb 5/8/2008 Pharmacist United States
Primary
Concomitant
Gastrointestinal Disorder Female 149 lb 2/27/2009 Physician United States
Primary
Concomitant
Lung Disorder Other Serious 1/16/2009 Female 3/11/2009 Physician United Kingdom
Primary
Concomitant
Visual Impairment Other Serious 4/15/2008 Female 3/14/2009 United Kingdom
Primary
Concomitant
Overdose Hospitalization 12/16/2008 Female 3/23/2009 Physician Denmark
Primary
Concomitant
Breast Cancer Female Other Serious 2/7/2000 Female 174 lb 3/24/2009 Lawyer United States
Primary
Secondary
Concomitant
Rash Male 3/31/2009 Consumer
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 12/1/2002 55 Male 192 lb 4/3/2009 United States
Primary
Concomitant
Lung Disorder Other Serious 1/16/2009 Female 4/8/2009 Physician United Kingdom
Primary
Concomitant
Condition Aggravated Other Serious 77 Female 4/9/2009 Consumer United States
Primary
Secondary
Concomitant
Death Death Female 4/15/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death Female 4/15/2009 Physician Slovenia
Primary
Secondary
Concomitant
Breast Cancer Female Other Serious 2/7/2000 Female 172 lb 4/22/2009 Lawyer United States
Primary
Secondary
Concomitant
Application Site Pruritus Disability 9/1/2008 Female 4/22/2009 Pharmacist United States
Primary
Concomitant
Rash Life Threatening 3/17/2009 64 Female 4/23/2009 Pharmacist United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/29/2009 77 Male 5/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
Yellow Skin Other Serious 5/1/2007 67 Male 165 lb 5/8/2009 Physician United States
Primary
Secondary
Concomitant
Blood Pressure Systolic Increased 1/1/2006 68 Male 5/8/2009 Consumer
Primary
Concomitant
Yellow Skin Other Serious 5/1/2007 67 Male 165 lb 5/11/2009 Physician United States
Primary
Secondary
Concomitant

Drug Data