Simvastatin combined with Sulfasalazine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pyrexia Hospitalization 3/1/2005 70 Male 1/12/2006 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Pleural Disorder Other Serious 9/21/2005 57 Male 216 lb 1/10/2006 Netherlands
Primary
Secondary
Concomitant
Pulmonary Fibrosis Death 8/25/2005 Female 1/20/2006 United Kingdom
Primary
Concomitant
Pleural Disorder Other Serious 9/21/2005 57 Male 216 lb 1/10/2006 Netherlands
Primary
Secondary
Concomitant
Cardiac Failure Congestive Required Intervention 1/25/2006 60 Male 281 lb 1/25/2006 Pharmacist United States
Primary
Concomitant
Peripheral Embolism Other Serious 12/15/2004 Female 1/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Life Threatening 9/23/2005 72 Male 176 lb 1/30/2006 Physician
Primary
Concomitant
Pneumonitis Death 6/1/2005 69 Male 1/30/2006 United Kingdom
Primary
Concomitant
Pneumonitis Death 6/1/2005 69 Male 2/6/2006 United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 3/1/2005 70 Male 2/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Subcutaneous Emphysema Other Serious 10/1/2003 Male 203 lb 2/9/2006 United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/1/2005 70 Male 2/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Fibrosis Death 8/25/2005 Female 148 lb 2/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 7/1/2003 67 Female 2/27/2006 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 3/1/2005 70 Male 2/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/1/2003 67 Female 190 lb 4/6/2006 Physician United States
Primary
Concomitant
Weight Decreased Life Threatening 11/1/2005 Male 4/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Osteomyelitis Hospitalization 10/15/2005 Male 176 lb 6/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Migraine Other Serious 3/10/2006 Female 155 lb 6/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Oedema Other Serious 9/4/2003 57 Female 8/21/2006 United States
Primary
Concomitant
Respiratory Failure Death 6/27/2005 Male 176 lb 9/1/2006 United Kingdom
Primary
Secondary
Concomitant
Obstruction Other Serious 6/28/2006 Female 205 lb 9/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Septic Shock Other Serious 9/25/2001 Male 10/9/2006 Physician Italy
Primary
Concomitant
Pyelonephritis Acute Other Serious 10/23/2006 46 Female 11/1/2006 Other Health Professional Thailand
Primary
Concomitant
Neoplasm Malignant Other Serious Female 205 lb 11/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Rate Increased Other Serious 10/23/2006 46 Female 11/13/2006 Other Health Professional Thailand
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 54 Female 11/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Synovitis Other Serious 9/4/2003 57 Female 11/17/2006 United States
Primary
Concomitant
Cerebral Infarction Hospitalization 5/15/2006 55 Male 216 lb 11/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 3/14/2005 Female 148 lb 12/15/2006 Consumer United Kingdom
Primary
Concomitant
Subcutaneous Emphysema Hospitalization 10/1/2003 66 Male 1/27/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Subcutaneous Emphysema Other Serious 10/1/2003 66 Male 2/1/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Femur Fracture Other Serious 10/15/2005 Female 3/2/2007 Other Health Professional Sweden
Primary
Concomitant
Joint Swelling Other Serious 11/1/2006 61 Female 269 lb 3/23/2007 United Kingdom
Primary
Secondary
Concomitant
Joint Swelling Other Serious 11/1/2006 61 Female 269 lb 3/23/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Joint Swelling Required Intervention 11/1/2006 61 Female 3/26/2007 United Kingdom
Primary
Secondary
Concomitant
Musculoskeletal Chest Pain Hospitalization 12/5/2006 Female 269 lb 5/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 1/1/2007 Female 157 lb 5/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 54 Female 5/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 12/5/2005 Female 269 lb 6/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Infection Death 2/15/2007 Male 132 lb 6/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Infection Death 2/15/2007 Male 132 lb 7/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 11/15/2006 Female 269 lb 7/27/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Musculoskeletal Chest Pain Hospitalization 12/5/2006 Female 269 lb 7/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pelvic Pain 7/27/2007 63 Female 159 lb 9/26/2007 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 4/15/2007 Male 132 lb 10/17/2007 Physician United Kingdom
Primary
Concomitant
Skin Irritation 8/1/2007 Male 12/14/2007 United States
Primary
Secondary
Concomitant
Breast Cancer Other Serious 12/10/2007 Female 161 lb 1/9/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Mass Other Serious 11/15/2007 Male 168 lb 1/18/2008 United Kingdom
Primary
Concomitant
Fall Hospitalization 4/27/2007 Male 159 lb 1/21/2008 United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 4/15/2007 Male 132 lb 3/4/2008 Physician United Kingdom
Primary
Concomitant
Swelling 10/1/2007 Female 145 lb 3/14/2008 Consumer United States
Primary
Concomitant
Tremor 12/1/2007 Female 147 lb 3/15/2008 Physician United States
Primary
Concomitant
Ear Congestion Other Serious 1/1/2008 Female 3/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Chest Pain Other Serious 3/1/2008 Female 194 lb 5/9/2008 Other Health Professional United Kingdom
Primary
Concomitant
Photophobia 1/1/2008 Female 233 lb 6/13/2008 Consumer United States
Primary
Concomitant
Pain Other Serious 11/1/2007 40 Male 7/1/2008 Physician United Kingdom
Primary
Concomitant
Neutropenic Sepsis Death 71 Female 7/4/2008 Other Health Professional United Kingdom
Primary
Concomitant
Back Pain Other Serious 11/1/2007 40 Male 7/14/2008 Physician United Kingdom
Primary
Concomitant
Neutropenic Sepsis Life Threatening 7/15/2008 57 Male 8/12/2008 Other Health Professional United Kingdom
Primary
Concomitant
Large Intestine Perforation Hospitalization Male 8/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 8/30/2007 Male 218 lb 9/19/2008 Physician United Kingdom
Primary
Concomitant
Large Intestine Perforation Hospitalization 12/1/2007 Male 9/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
Wound Infection Hospitalization 6/1/2006 Female 128 lb 9/23/2008 Consumer Brazil
Primary
Concomitant
Pancreatic Carcinoma Metastatic Life Threatening 60 Male 165 lb 10/6/2008 Other Health Professional United Kingdom
Primary
Concomitant
Bladder Transitional Cell Carcinoma Other Serious 6/19/2008 Male 240 lb 10/6/2008 United Kingdom
Primary
Concomitant
Thrombosis Other Serious 2/13/2008 63 Male 214 lb 10/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Infection Other Serious 12/1/2007 Female 300 lb 11/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 9/1/2008 77 Male 150 lb 11/17/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 65 Female 12/1/2008 United States
Primary
Secondary
Concomitant
Urinary Retention Other Serious 11/19/2008 54 Male 12/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Retention Other Serious 11/19/2008 54 Male 12/11/2008 Other Health Professional United Kingdom
Primary
Concomitant
Tendon Rupture Hospitalization 50 Male 12/11/2008 Physician Finland
Primary
Concomitant
White Blood Cell Count Increased Death 6/25/2008 Female 12/23/2008 Physician New Zealand
Primary
Secondary
Concomitant
Pelvic Mass Hospitalization 1/1/2007 Female 1/5/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/25/2008 Female 2/3/2009 Physician New Zealand
Primary
Secondary
Concomitant
Angioedema Hospitalization 1/22/2009 2/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Mass Other Serious 11/15/2007 Male 168 lb 3/31/2009 United Kingdom
Primary
Concomitant
Wound Infection Other Serious 8/1/2008 Female 4/10/2009 United Kingdom
Primary
Concomitant
Feeling Abnormal 63 Male 180 lb 4/22/2009 Pharmacist United States
Primary
Concomitant
Swollen Tongue Life Threatening 1/1/2009 62 Female 159 lb 5/11/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rhinorrhoea 3/1/2009 Female 5/21/2009 Consumer
Primary
Concomitant
Subdural Haematoma Life Threatening 4/1/2009 73 Female 5/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nasopharyngitis 4/5/2009 Female 120 lb 6/12/2009 United States
Primary
Concomitant
Injection Site Pain 5/1/2009 Female 152 lb 6/12/2009 Consumer United States
Primary
Concomitant
Knee Arthroplasty Hospitalization 4/22/2009 Female 187 lb 6/15/2009 Czech Republic
Primary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 5/7/2009 Male 274 lb 6/18/2009 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 9/1/2008 77 6/30/2009 United Kingdom
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Other Serious 4/15/2009 64 Male 7/15/2009 Physician Spain
Primary
Concomitant
Renal Cancer Other Serious 1/1/2003 Female 189 lb 7/24/2009 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 9/30/2008 54 Male 7/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2005 Female 436 lb 7/29/2009 Consumer United States
Primary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 5/7/2009 Male 274 lb 8/7/2009 Physician United States
Primary
Secondary
Concomitant
Peripheral Ischaemia Hospitalization 6/23/2009 Female 168 lb 8/11/2009 United Kingdom
Primary
Concomitant
Meningioma Hospitalization 5/15/2009 Male 245 lb 8/14/2009 United Kingdom
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 8/10/2009 United States
Primary
Concomitant
Sepsis Death 2/21/2009 Female 231 lb 8/17/2009 United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/13/2009 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/23/2009 Lawyer United States
Primary
Concomitant
Meningioma Other Serious 4/9/2009 Male 245 lb 9/3/2009 United Kingdom
Primary
Concomitant
Wound Infection Other Serious 8/1/2008 Female 9/3/2009 United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 5/18/2009 63 Female 131 lb 9/10/2009 Physician United Kingdom
Primary
Concomitant
Incorrect Dose Administered 8/30/2007 Female 196 lb 9/12/2009 Consumer United States
Primary
Concomitant
Photophobia 1/1/2008 Female 233 lb 9/12/2009 Consumer United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 9/17/2009 United States
Primary
Concomitant
Pancytopenia Hospitalization 9/1/2008 77 10/1/2009 United Kingdom
Primary
Secondary
Concomitant
Psoriatic Arthropathy Other Serious 1/1/2008 Female 244 lb 10/1/2009 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 12/11/2008 57 Female 165 lb 12/14/2009 Other Health Professional United Kingdom
Primary
Concomitant
Breast Cancer Other Serious 12/22/2009 75 Female 1/6/2010 Other Health Professional United States
Primary
Concomitant
Sepsis Life Threatening 5/12/2008 71 Female 1/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pruritus 8/1/2009 Female 145 lb 1/29/2010 Consumer United States
Primary
Concomitant
Breast Cancer In Situ Other Serious 12/22/2009 Female 117 lb 2/5/2010 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Hospitalization Male 146 lb 4/7/2010 Other Health Professional Germany
Primary
Concomitant
Sepsis Other Serious 10/1/2009 54 Female 172 lb 4/23/2010 Pharmacist United States
Primary
Concomitant
Colitis Ischaemic Hospitalization 4/1/2010 81 Female 127 lb 5/7/2010 Physician United States
Primary
Concomitant
Rheumatoid Lung Other Serious 9/1/2009 72 Female 5/14/2010 Physician Germany
Primary
Concomitant
Tuberculosis Hospitalization Male 146 lb 5/18/2010 Physician Germany
Primary
Concomitant
Respiratory Failure Hospitalization 12/1/2009 72 Male 146 lb 5/27/2010 Physician Germany
Primary
Concomitant
Pancreatitis Hospitalization 1/1/2010 54 Female 5/28/2010 Other Health Professional United States
Primary
Concomitant
Sinusitis Hospitalization 7/1/2009 48 Male 250 lb 6/18/2010 Consumer United States
Primary
Concomitant
Respiratory Failure Hospitalization 9/11/2009 72 Male 146 lb 6/9/2010 Other Health Professional Germany
Primary
Concomitant
Respiratory Failure Hospitalization 9/11/2009 72 Male 146 lb 6/24/2010 Physician Germany
Primary
Concomitant
Respiratory Failure Hospitalization 9/11/2009 72 Male 146 lb 7/12/2010 Physician Germany
Primary
Concomitant
Neutropenic Sepsis Hospitalization 3/5/2010 81 Male 187 lb 7/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Lung Other Serious 9/1/2009 72 Female 8/11/2010 Physician Germany
Primary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 5/7/2009 63 Male 274 lb 8/23/2010 Physician United States
Primary
Concomitant
Flushing Male 275 lb 8/28/2010 United States
Primary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 5/7/2009 63 Male 274 lb 9/2/2010 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 1/1/2010 77 Female 77 lb 9/9/2010 Physician Japan
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 9/10/2010 Other Health Professional Singapore
Primary
Secondary
Pain Hospitalization 6/21/2010 75 Male 9/13/2010 Physician Germany
Primary
Concomitant
Colitis Ischaemic Hospitalization 4/1/2010 81 Female 127 lb 10/28/2010 Physician United States
Primary
Concomitant
Wound Infection Hospitalization 8/31/2010 55 Male 11/18/2010 Physician United Kingdom
Primary
Concomitant
Colitis Ischaemic Hospitalization 4/1/2010 81 Female 127 lb 11/29/2010 Physician United States
Primary
Concomitant
Pseudomembranous Colitis Hospitalization 4/1/2010 81 Female 127 lb 12/13/2010 Physician United States
Primary
Concomitant
Red Blood Cell Count Decreased Hospitalization 4/1/2010 81 Female 127 lb 12/17/2010 Physician United States
Primary
Concomitant
Sinusitis 12/19/2010 Consumer United States
Primary
Concomitant
Influenza Like Illness 6/19/2010 12/22/2010 Consumer United States
Primary
Concomitant
Sinus Headache 6/4/2010 12/22/2010 Consumer United States
Primary
Concomitant
Headache Other Serious 10/30/2010 56 Female 160 lb 1/11/2011 Physician Germany
Primary
Interacting
Arthralgia 11/15/2009 60 Male 241 lb 1/28/2011 Consumer United States
Primary
Concomitant
Metabolic Acidosis Hospitalization 12/18/2010 48 Female 2/9/2011 Other Health Professional Finland
Primary
Concomitant
Off Label Use Hospitalization 12/18/2010 48 Female 2/18/2011 Other Health Professional Finland
Primary
Secondary
Concomitant
Fatigue Other Serious 1/1/2007 57 Male 3/7/2011 Consumer United States
Primary
Concomitant
Lung Infiltration Hospitalization 11/11/2009 72 Male 146 lb 3/18/2011 Other Health Professional Germany
Primary
Concomitant
Skin Cancer Other Serious 2/16/2011 83 Male 4/7/2011 Physician United States
Primary
Concomitant
Bronchopulmonary Aspergillosis Hospitalization 11/11/2009 72 Male 146 lb 4/1/2011 Other Health Professional Germany
Primary
Concomitant
Pneumonia Other Serious 2/16/2011 83 Male 4/19/2011 Physician United States
Primary
Concomitant
Leg Amputation Other Serious 1/1/2011 70 Female 4/14/2011 United States
Primary
Concomitant
Pneumonia Death 11/15/2010 82 Male 4/29/2011 Physician United States
Primary
Concomitant

Drug Data