Simvastatin combined with Valsartan

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urinary Retention Other Serious 8/15/2005 Male 1/5/2006 United Kingdom
Primary
Secondary
Concomitant
Hypersensitivity Required Intervention 11/14/2005 79 Male 208 lb 11/16/2005 Pharmacist United States
Primary
Concomitant
Lactic Acidosis Required Intervention 11/14/2005 57 Male 286 lb 1/24/2006 Pharmacist United States
Primary
Concomitant
Hypotension Hospitalization 10/3/2005 79 Male 193 lb 10/5/2005 Pharmacist United States
Primary
Secondary
Concomitant
Dizziness Postural Hospitalization 10/12/2005 Male 144 lb 10/13/2005 Pharmacist United States
Primary
Secondary
Concomitant
Somnolence 5/23/2005 79 Female 166 lb 1/5/2006 Consumer United States
Primary
Concomitant
Procedural Site Reaction Hospitalization 11/21/2005 Male 2/15/2006 Pharmacist United States
Primary
Concomitant
Headache Other Serious 1/31/2006 77 Male 199 lb 1/31/2006 Pharmacist United States
Primary
Concomitant
Speech Disorder Other Serious 10/1/2005 83 Male 174 lb 1/20/2006 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 7/26/2005 67 Male 161 lb 2/14/2006 Physician Italy
Primary
Concomitant
Transient Ischaemic Attack Other Serious 9/1/2001 70 Female 126 lb 4/14/2006 Physician Canada
Primary
Concomitant
Urinary Retention Hospitalization 8/15/2005 Male 215 lb 4/24/2006 United Kingdom
Primary
Secondary
Concomitant
Macular Degeneration Other Serious 3/1/2006 Male 209 lb 5/8/2006 Physician Denmark
Primary
Concomitant
Renal Failure Hospitalization 3/17/2006 70 Male 5/10/2006 United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Hospitalization 1/16/2006 Male 5/16/2006 Pharmacist United States
Primary
Concomitant
Headache 10/22/2005 73 Female 154 lb 4/3/2006 Consumer United States
Primary
Concomitant
Muscle Twitching 9/1/2005 81 Female 3/13/2006 Other Health Professional United States
Primary
Concomitant
Intentional Drug Misuse Other Serious 71 Male 238 lb 4/20/2006 United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 4/24/2006 67 Male 7/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Blood Potassium Increased Hospitalization 6/19/2006 67 Male 7/7/2006 Pharmacist United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 6/27/2006 56 Female 196 lb 7/14/2006 Physician Italy
Primary
Secondary
Concomitant
Thrombosis Other Serious 66 Male 7/28/2006 Pharmacist Germany
Primary
Concomitant
Blood Creatine Phosphokinase Increased 5/22/2006 65 Female 301 lb 7/6/2006 Pharmacist United States
Primary
Concomitant
Hypotension Hospitalization 6/27/2006 62 Male 8/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Life Threatening 6/9/2006 75 Male 251 lb 8/17/2006 Consumer United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 6/27/2006 56 Female 196 lb 8/11/2006 Physician Italy
Primary
Secondary
Concomitant
Pulse Abnormal Other Serious 71 Female 6/6/2006 United States
Primary
Concomitant
Urinary Retention Hospitalization 8/15/2005 Male 215 lb 9/11/2006 United Kingdom
Primary
Secondary
Concomitant
Injection Site Cellulitis Hospitalization 10/11/2005 56 Male 234 lb 9/25/2006 Physician United Kingdom
Primary
Concomitant
Rash Other Serious 7/18/2006 74 Male 341 lb 7/18/2006 Pharmacist United States
Primary
Concomitant
Hyponatraemia Other Serious 12/22/2005 71 Male 129 lb 9/28/2006 Pharmacist United States
Primary
Concomitant
Mallory-weiss Syndrome Hospitalization 8/14/2006 80 Male 10/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Cerebrovascular Accident Hospitalization 6/18/2006 87 Male 179 lb 10/4/2006 Pharmacist United States
Primary
Concomitant
Tachycardia Hospitalization 9/28/2006 76 Male 200 lb 10/17/2006 Pharmacist United States
Primary
Concomitant
Muscle Spasms Other Serious 8/2/2006 79 Male 165 lb 9/15/2006 Pharmacist United States
Primary
Concomitant
Myalgia Other Serious 8/20/2006 71 Male 155 lb 9/15/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 68 Female 11/8/2006 Other Health Professional Lebanon
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Hospitalization 52 Female 11/13/2006 Other Health Professional Israel
Primary
Secondary
Concomitant
Tremor Hospitalization 9/15/2006 61 Male 11/20/2006 Consumer United Kingdom
Primary
Concomitant
Urinary Retention Hospitalization 8/15/2005 Male 215 lb 11/28/2006 United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 3/6/2006 79 Male 11/17/2006 Physician United Kingdom
Primary
Concomitant
Hidradenitis Hospitalization 68 Female 12/15/2006 Other Health Professional Lebanon
Primary
Concomitant
Macular Degeneration Other Serious 5/1/2006 Female 12/11/2006 Brazil
Primary
Concomitant
Treatment Noncompliance Other Serious 1/1/2006 70 Male 198 lb 12/13/2006 Physician Germany
Primary
Concomitant
Hidradenitis Other Serious 68 Female 12/20/2006 Lebanon
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 9/4/2006 52 Female 154 lb 9/8/2006 United States
Primary
Concomitant
Myalgia Other Serious 12/19/2006 60 Female 199 lb 12/21/2006 Pharmacist United States
Primary
Concomitant
Hypoaesthesia Hospitalization 11/7/2006 84 Female 1/31/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 12/29/2006 66 Male 173 lb 1/26/2007 Physician United Kingdom
Primary
Secondary
Liver Function Test Abnormal Hospitalization 12/11/2006 Female 2/1/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Pancreatic Carcinoma Hospitalization 11/7/2006 84 Female 2/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Post Procedural Complication Hospitalization 2/2/2007 80 Female 146 lb 2/7/2007 Pharmacist United States
Primary
Concomitant
Hypoglycaemia Hospitalization 2/8/2007 59 Male 138 lb 2/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Rash Hospitalization 2/12/2007 Male 194 lb 2/15/2007 Pharmacist United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 2/14/2007 Male 2/22/2007 Other Health Professional United States
Primary
Concomitant
Poor Quality Drug Administered 12/14/2006 62 Female 139 lb 2/12/2007 Pharmacist United States
Primary
Concomitant
Muscle Spasms Other Serious 9/1/2006 Male 211 lb 12/15/2006 Pharmacist United States
Primary
Concomitant
Polymyalgia Rheumatica Disability 6/1/2006 55 Female 140 lb 3/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pain In Extremity Disability 6/1/2006 55 Female 140 lb 3/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rectal Haemorrhage Other Serious 12/29/2006 74 Male 251 lb 3/26/2007 United States
Primary
Secondary
Concomitant
Convulsion Other Serious 3/12/2007 Male 149 lb 3/27/2007 Consumer United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 12/29/2006 74 Male 251 lb 3/30/2007 United States
Primary
Secondary
Concomitant
Heart Rate Irregular 10/1/2006 60 Female 184 lb 1/12/2007 Consumer United States
Primary
Concomitant
Insomnia 10/1/2006 73 Female 148 lb 1/12/2007 Consumer United States
Primary
Concomitant
Middle Insomnia 10/1/2006 85 Male 172 lb 1/12/2007 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2006 74 Male 217 lb 4/11/2007 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/11/2006 Female 4/16/2007 Other Health Professional Japan
Primary
Concomitant
Interacting
Refusal Of Treatment By Patient Other Serious 1/25/2007 58 Male 247 lb 4/12/2007 United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2006 74 Male 216 lb 4/30/2007 Consumer United States
Primary
Concomitant
Delirium Hospitalization 1/16/2007 89 Male 240 lb 1/17/2007 Pharmacist United States
Primary
Concomitant
Somnolence 3/9/2007 73 Female 230 lb 5/3/2007 United States
Primary
Concomitant
Nausea 60 Female 184 lb 2/6/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 85 Male 172 lb 2/6/2007 Consumer United States
Primary
Concomitant
Convulsion Other Serious 3/12/2007 Male 149 lb 5/18/2007 Physician United States
Primary
Secondary
Concomitant
Initial Insomnia 1/1/2007 52 Female 212 lb 4/12/2007 Consumer United States
Primary
Concomitant
Insomnia 1/1/2006 55 Male 350 lb 4/12/2007 Consumer United States
Primary
Concomitant
Syncope Hospitalization 6/16/2004 82 Male 3/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo Other Serious 3/1/2007 70 Male 6/8/2007 Physician Hungary
Primary
Concomitant
Toxic Induced Encephalopathy Hospitalization 2/28/2007 Female 167 lb 6/9/2007 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 67 Male 251 lb 6/15/2007 Physician United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2006 74 Male 216 lb 6/12/2007 Consumer United States
Primary
Concomitant
Tongue Disorder Other Serious 1/1/2002 Female 154 lb 6/29/2007 Consumer Brazil
Primary
Concomitant
Rash Other Serious 2/22/2006 34 Female 290 lb 5/22/2007 Physician United States
Primary
Concomitant
Hypoglycaemia Other Serious 6/4/2007 61 Female 190 lb 7/3/2007 United Kingdom
Primary
Secondary
Concomitant
Tongue Disorder Other Serious 1/1/2002 Female 154 lb 7/13/2007 Consumer Brazil
Primary
Concomitant
Incision Site Infection Hospitalization Female 130 lb 7/23/2007 Canada
Primary
Concomitant
Pancreatic Carcinoma Hospitalization 11/7/2006 84 Female 7/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Feeling Abnormal Other Serious 6/23/2007 77 Female 182 lb 8/2/2007 Consumer United Kingdom
Primary
Concomitant
Dysgeusia 5/1/2007 52 Female 168 lb 7/10/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 6/22/2007 61 Female 181 lb 8/21/2007 Physician United States
Primary
Secondary
Concomitant
Tongue Disorder Other Serious 1/1/2002 Female 154 lb 8/27/2007 Consumer Brazil
Primary
Concomitant
Nausea 10/1/2006 74 Male 216 lb 7/11/2007 Consumer United States
Primary
Concomitant
Kidney Transplant Rejection Hospitalization 12/14/2006 26 Female 205 lb 12/18/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Life Threatening 8/9/2007 76 Female 152 lb 9/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Somnolence Other Serious 7/1/2007 Female 249 lb 9/17/2007 Physician Germany
Primary
Concomitant
Back Pain 3/1/2007 Male 291 lb 9/20/2007 Consumer United States
Primary
Concomitant
Visual Disturbance 6/13/2007 62 Female 7/5/2007 Consumer United States
Primary
Concomitant
Melaena Hospitalization 9/16/2007 69 Female 10/16/2007 Physician
Primary
Secondary
Concomitant
Feeling Abnormal Other Serious 6/23/2007 77 Female 187 lb 10/19/2007 Physician United Kingdom
Primary
Concomitant
Retinal Detachment Hospitalization 10/1/2007 63 Female 10/24/2007 Pharmacist Netherlands
Primary
Secondary
Concomitant
Angioedema Life Threatening 8/3/2007 60 Female 11/5/2007 Physician United Kingdom
Primary
Concomitant
Dizziness Male 11/13/2007 Consumer United States
Primary
Concomitant
Restlessness 10/29/2007 64 Male 220 lb 11/13/2007 Physician United States
Primary
Concomitant
Angioedema Life Threatening 8/3/2007 60 Female 11/26/2007 Physician United Kingdom
Primary
Concomitant
Oedema Hospitalization 3/15/2006 80 Male 11/26/2007 Other Health Professional France
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/29/2007 64 Male 220 lb 11/19/2007 Physician United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/10/2007 Male 11/30/2007 Physician Germany
Primary
Concomitant
Interacting
Pain Other Serious 10/18/2007 Male 12/4/2007 Pharmacist United Kingdom
Primary
Concomitant
Rectal Cancer Metastatic Hospitalization 6/1/2007 87 Male 143 lb 11/30/2007 Consumer Germany
Primary
Concomitant
Liver Disorder Other Serious 9/1/2007 Male 12/10/2007 Other Health Professional Germany
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 10/29/2007 64 Male 220 lb 12/7/2007 United States
Primary
Concomitant
Thirst Other Serious 12/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Peritonitis Bacterial 11/23/2007 75 Male 12/19/2007 Canada
Primary
Concomitant
Gastric Ulcer Hospitalization 69 Female 12/13/2007 Korea, Republic Of
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/1/2007 87 Male 143 lb 12/14/2007 Consumer Germany
Primary
Concomitant
Gout Hospitalization 10/26/2007 Male 260 lb 12/21/2007 Sweden
Primary
Concomitant
Peritonitis Bacterial 11/23/2007 75 Male 12/27/2007 Canada
Primary
Concomitant
Oedema Peripheral Other Serious 11/1/2007 74 Female 207 lb 12/28/2007 Physician United Kingdom
Primary
Concomitant
Erectile Dysfunction 9/1/2007 64 Male 1/2/2008 Other Health Professional United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 9/2/2007 Female 119 lb 1/7/2008 Physician Japan
Primary
Secondary
Retinal Detachment Hospitalization 10/1/2007 Female 2/5/2008 Pharmacist Netherlands
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 1/6/2008 79 Female 154 lb 2/10/2008 Physician Brazil
Primary
Secondary
Concomitant
Panic Attack Other Serious 1/1/2007 2/12/2008 Consumer Portugal
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 9/2/2007 Female 119 lb 2/12/2008 Physician Japan
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Life Threatening Female 2/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Memory Impairment Other Serious 2/8/2008 Male 251 lb 2/22/2008 United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 11/1/2007 Female 3/15/2008 Consumer United States
Primary
Concomitant
Tremor Other Serious 2/1/2008 Male 165 lb 3/17/2008 Physician United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 5/1/2007 87 Male 143300 lb 3/14/2008 Physician Germany
Primary
Concomitant
Respiratory Distress Required Intervention 2/1/2008 74 Male 191 lb 4/10/2008 Physician United States
Primary
Concomitant
Paraesthesia Other Serious 2/8/2008 Male 251 lb 4/16/2008 United States
Primary
Concomitant
Overdose Other Serious 1/1/2008 84 Female 4/18/2008 Physician United Kingdom
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 1/15/2008 Female 187 lb 4/24/2008 Physician United Kingdom
Primary
Concomitant
Infusion Related Reaction Hospitalization 4/1/2008 63 Male 4/30/2008 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 1/1/2006 Male 135 lb 5/8/2008 Physician United States
Primary
Concomitant
Wrong Drug Administered Hospitalization 4/23/2008 79 Female 108 lb 5/15/2008 Pharmacist United States
Primary
Concomitant
Pruritus 4/14/2008 Female 200 lb 5/28/2008 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 10/27/2007 Female 6/4/2008 Physician United Kingdom
Primary
Concomitant
Hypotonia Other Serious 5/4/2008 Female 6/9/2008 Physician United Kingdom
Primary
Concomitant
Nausea Male 6/13/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 5/1/2007 87 Male 143 lb 6/11/2008 Consumer Germany
Primary
Concomitant
Renal Neoplasm Other Serious 3/12/2008 Female 6/19/2008 United Kingdom
Primary
Concomitant
Thrombocytopenia Hospitalization 6/2/2008 41 Male 6/26/2008 Other Health Professional United Kingdom
Primary
Concomitant
Haemolytic Anaemia Other Serious 4/3/2008 Female 6/30/2008 Physician Japan
Primary
Concomitant
Death Death 76 Female 172 lb 7/3/2008 Consumer Brazil
Primary
Concomitant
Myocardial Infarction Other Serious 10/26/2007 Female 7/15/2008 Physician United Kingdom
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 1/15/2008 Female 187 lb 7/16/2008 Physician United Kingdom
Primary
Concomitant
Wheezing Hospitalization 7/22/2008 65 Female 8/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wheezing Hospitalization 7/22/2008 65 Female 8/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pruritus 9/12/2007 Female 160 lb 8/27/2008 Consumer United States
Primary
Concomitant

Drug Data