Simvastatin combined with Tiotropium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sedation Hospitalization 2/19/2005 Female 2/24/2006 Consumer Australia
Primary
Secondary
Concomitant
Simple Partial Seizures Hospitalization 5/13/2006 57 Male 7/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Headache Other Serious 6/14/2006 63 Male 255 lb 6/14/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/26/2006 72 Male 11/28/2006 Pharmacist United Kingdom
Primary
Concomitant
Abdominal Pain Other Serious 1/9/2007 69 Male 198 lb 1/17/2007 Pharmacist United States
Primary
Concomitant
Diarrhoea Other Serious 12/28/2006 75 Male 140 lb 1/31/2007 Pharmacist United States
Primary
Concomitant
Hallucination Hospitalization 1/2/2007 60 Male 5/9/2007 Pharmacist United States
Primary
Concomitant
Yellow Skin Hospitalization Male 11/19/2007 Physician Australia
Primary
Concomitant
Oedema Peripheral Hospitalization 59 5/6/2008 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious 10/27/2007 Female 6/4/2008 Physician United Kingdom
Primary
Concomitant
Oedema Peripheral Hospitalization 59 6/11/2008 Physician United States
Primary
Concomitant
Cervix Carcinoma Other Serious Female 204 lb 6/20/2008 Consumer United Kingdom
Primary
Concomitant
Sepsis Other Serious 5/2/2008 Male 212 lb 7/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Cervical Dysplasia Hospitalization 5/31/2008 Female 204 lb 7/14/2008 Consumer United Kingdom
Primary
Concomitant
Gait Disturbance Hospitalization 76 Male 1/4/2008 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Other Serious 10/26/2007 Female 7/15/2008 Physician United Kingdom
Primary
Concomitant
Swelling Face Other Serious 71 Female 7/29/2008 United States
Primary
Concomitant
Angina Pectoris Hospitalization 6/4/2008 Female 8/13/2008 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/1/2008 76 Male 9/9/2008 Consumer United Kingdom
Primary
Secondary
Lower Respiratory Tract Infection Hospitalization 1/1/2008 71 Male 10/23/2008 Consumer United Kingdom
Primary
Secondary
Feeling Abnormal Other Serious 70 Male 238 lb 11/10/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 7/1/2008 76 Male 11/17/2008 Physician United Kingdom
Primary
Secondary
Cerebellar Haemorrhage Hospitalization 3/15/2008 81 Male 168 lb 6/16/2008 United States
Primary
Concomitant
Feeling Abnormal Other Serious 70 Male 238 lb 11/25/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Failure Life Threatening 11/17/2008 53 Female 11/26/2008 Norway
Primary
Concomitant
Feeling Abnormal Other Serious Male 12/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 10/1/2004 64 Male 170 lb 12/12/2008 Pharmacist United States
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 1/1/2008 71 Male 12/18/2008 Consumer United Kingdom
Primary
Secondary
General Physical Health Deterioration Hospitalization 12/12/2008 12/24/2008 Physician Belgium
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 12/12/2008 1/2/2009 Physician Belgium
Primary
Secondary
Concomitant
Oesophagitis Other Serious 10/1/2008 77 Female 146 lb 1/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 12/12/2008 67 Female 1/21/2009 Other Health Professional Belgium
Primary
Secondary
Concomitant
Pseudoporphyria Other Serious 1/1/2007 65 Male 2/20/2009 Physician United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 1/1/2008 Male 3/30/2009 Consumer United Kingdom
Primary
Secondary
Oxygen Saturation Decreased Hospitalization 1/1/2008 Male 3/30/2009 Consumer United Kingdom
Primary
Secondary
Urinary Tract Infection Hospitalization 1/29/2009 77 Male 5/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
Somnolence Other Serious Male 6/29/2009 Consumer United States
Primary
Secondary
Concomitant
Syncope Other Serious 5/26/2009 8/6/2009 Physician Italy
Primary
Concomitant
Sepsis Hospitalization Male 8/14/2009 Physician United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 7/24/2009 85 Male 8/27/2009 Pharmacist United States
Primary
Concomitant
Rash Hospitalization 6/15/2008 63 Female 10/8/2009 United Kingdom
Primary
Concomitant
Respiratory Distress 10/29/2009 72 Male 11/27/2009 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Life Threatening 12/8/2009 Female 161 lb 12/11/2009 United States
Primary
Concomitant
Urinary Retention Hospitalization 74 Male 176 lb 1/14/2010
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 74 Male 176 lb 2/25/2010
Primary
Secondary
Concomitant
Volvulus Other Serious 1/21/2010 64 Male 4/6/2010 Pharmacist United Kingdom
Primary
Concomitant
Withdrawal Of Life Support Hospitalization 71 Female 110 lb 4/27/2010 Physician United States
Primary
Concomitant
General Physical Health Deterioration Hospitalization 12/12/2008 67 Female 150 lb 6/15/2010 Physician Belgium
Primary
Secondary
Concomitant
Delirium Hospitalization 8/18/2009 75 Female 6/25/2010 Other Health Professional Denmark
Primary
Concomitant
General Physical Health Deterioration Hospitalization 12/12/2008 67 Female 150 lb 7/2/2010 Physician Belgium
Primary
Secondary
Concomitant
Osteonecrosis Other Serious Male 7/8/2010 Pharmacist United Kingdom
Primary
Concomitant
Urine Output Decreased Hospitalization 71 Female 110 lb 7/2/2010 Physician United States
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Other Serious 4/1/2008 73 Female 7/20/2010 Lawyer United States
Primary
Concomitant
Pneumonia Hospitalization 2/1/2008 58 Male 7/22/2010 Lawyer United States
Primary
Concomitant
Respiratory Failure Required Intervention 71 Female 7/31/2010 Other Health Professional United States
Primary
Concomitant
General Physical Health Deterioration Hospitalization 12/12/2008 67 Female 150 lb 8/24/2010 Physician Belgium
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Other Serious 3/18/2008 73 Female 9/14/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 12/12/2008 67 Female 9/10/2010 Other Health Professional Belgium
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/1/2008 58 Male 9/17/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 8/9/2010 76 Female 9/23/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 8/9/2010 76 Female 9/24/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 8/9/2010 76 Female 9/28/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 8/10/2010 60 Male 209 lb 9/27/2010 Pharmacist United States
Primary
Concomitant
Chills Other Serious 71 Female 10/5/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 8/9/2010 76 Female 10/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Death 8/9/2010 76 Female 10/21/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Death 8/9/2010 76 Female 10/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Fatigue Other Serious 8/3/2009 77 Male 11/8/2010 Pharmacist United States
Primary
Concomitant
Pulmonary Arterial Pressure Increased Other Serious 77 Male 11/15/2010 Pharmacist United States
Primary
Concomitant
Gastrointestinal Viral Infection Hospitalization 7/26/2010 83 Male 176 lb 10/12/2010 Germany
Primary
Concomitant
Tremor Other Serious 71 Female 117 lb 12/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Terminal State Other Serious 9/1/2009 69 Male 165 lb 12/3/2010 Consumer Netherlands
Primary
Concomitant
Pneumonia Hospitalization 9/1/2009 69 Male 165 lb 12/13/2010 Consumer Netherlands
Primary
Concomitant
Pneumonia Hospitalization 2/1/2008 58 Male 12/20/2010 Other Health Professional United States
Primary
Concomitant
Fungal Infection Hospitalization 9/1/2009 69 Male 165 lb 1/12/2011 Consumer Netherlands
Primary
Concomitant
Pubis Fracture Hospitalization 12/23/2010 77 Female 1/28/2011 Consumer Netherlands
Primary
Concomitant
Headache Other Serious 6/21/2010 Male 2/1/2011 Physician Switzerland
Primary
Concomitant
Pericardial Effusion Hospitalization 1/22/2011 55 Female 134 lb 2/7/2011 Physician United States
Primary
Secondary
Concomitant
Spinal Compression Fracture Other Serious 12/23/2010 77 Female 3/1/2011 Consumer Netherlands
Primary
Concomitant
Constipation Hospitalization 8/1/2009 71 Female 3/1/2011 Consumer United States
Primary
Concomitant
Interacting
Pericardial Effusion Hospitalization 1/22/2011 55 Female 134 lb 3/4/2011 Physician United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 12/3/2009 75 Male 3/8/2011 Other Health Professional Switzerland
Primary
Concomitant
Cerebral Ischaemia Hospitalization 1/1/2007 68 Male 3/3/2011 Physician United States
Primary
Concomitant
Blood Alkaline Phosphatase Increased Other Serious 12/18/2010 3/12/2011 Other Health Professional United States
Primary
Concomitant
Infected Cyst Other Serious 8/1/2009 71 Female 4/4/2011 Consumer United States
Primary
Concomitant
Interacting
Anaphylactic Reaction Other Serious 3/18/2011 81 Male 3/30/2011 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 1/26/2011 63 Male 187 lb 4/14/2011 Physician United Kingdom
Primary
Concomitant
Leukocytosis Hospitalization 3/20/2011 4/20/2011 Physician United States
Primary
Concomitant
Neutropenic Infection Other Serious 12/9/2010 79 Male 170 lb 4/21/2011 Consumer United Kingdom
Primary
Concomitant
Hypoaesthesia Hospitalization 1/26/2011 63 Male 187 lb 4/27/2011 Physician United Kingdom
Primary
Concomitant
Renal Cell Carcinoma Other Serious 12/18/2010 4/29/2011 Other Health Professional United States
Primary
Concomitant
Thrombosis Other Serious 1/26/2011 63 Male 187 lb 5/26/2011 Physician United Kingdom
Primary
Concomitant
Feeling Cold Hospitalization 1/26/2011 63 Male 187 lb 5/26/2011 Physician United Kingdom
Primary
Concomitant
Fall Death 2/5/2010 77 Male 6/1/2011 Consumer United Kingdom
Primary
Concomitant
Oral Discomfort Other Serious 5/1/2011 70 Male 5/26/2011 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 75 Female 179 lb 6/2/2011 Physician United States
Primary
Secondary
Concomitant
Oral Discomfort Other Serious 5/1/2011 70 Male 6/9/2011 Pharmacist United States
Primary
Concomitant
Pubis Fracture Other Serious 12/23/2010 77 Female 6/9/2011 Physician Netherlands
Primary
Concomitant
Lymph Node Pain Other Serious 8/1/2009 71 Female 6/15/2011 Consumer United States
Primary
Concomitant
Interacting
Hepatic Congestion Death 3/20/2011 6/27/2011 Physician United States
Primary
Concomitant
Nephropathy Hospitalization 7/10/2010 67 Male 7/1/2011 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Neoplasm Malignant Death 8/9/2010 76 Female 7/13/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebral Haemorrhage Hospitalization 8/9/2010 76 Female 7/13/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nausea Hospitalization 75 Female 179 lb 8/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Hospitalization 8/1/2009 71 Female 8/1/2011 Consumer United States
Primary
Concomitant
Interacting
Osteoarthritis Other Serious Male 8/30/2011 Other Health Professional United States
Primary
Concomitant
Nasopharyngitis Hospitalization 8/1/2009 71 Female 9/5/2011 Consumer United States
Primary
Concomitant
Interacting
Hypotension Hospitalization 6/26/2011 71 Male 185 lb 8/15/2011 Pharmacist United States
Primary
Concomitant
Aortic Valve Sclerosis Other Serious Male 9/7/2011 Other Health Professional United States
Primary
Concomitant
Dermatitis Other Serious 8/15/2011 72 Female 137 lb 10/12/2011 Other Health Professional United Kingdom
Primary
Concomitant
Aortic Valve Incompetence Other Serious Male 10/28/2011 Lawyer United States
Primary
Concomitant
Atrioventricular Block Complete Hospitalization 8/15/2011 78 Male 11/11/2011 Other Health Professional Spain
Primary
Concomitant
Leukocytosis Life Threatening 82 115 lb 11/2/2011 Lawyer United States
Primary
Concomitant
Death Death 8/27/2010 82 Male 12/1/2011 Physician United Kingdom
Primary
Concomitant
Neutrophil Count Increased Hospitalization 12/11/2011 49 Female 1/11/2012 Other Health Professional United Kingdom
Primary
Concomitant
Hypophagia Other Serious 12/17/2011 88 Female 1/23/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 12/11/2011 49 Female 2/6/2012 Physician United Kingdom
Primary
Concomitant
Ventricular Hypertrophy Hospitalization Male 2/6/2012 Lawyer United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 83 Male 3/28/2012 Other Health Professional Belgium
Primary
Concomitant
Interacting
Chronic Obstructive Pulmonary Disease Hospitalization Female 3/29/2012 Consumer United States
Primary
Concomitant
Fluid Intake Reduced Hospitalization Female 4/2/2012 Consumer United States
Primary
Concomitant
Cough 2/1/2011 58 Male 222 lb 1/3/2012 Other Health Professional United States
Primary
Concomitant
Small Intestinal Resection Hospitalization 11/29/2011 84 Male 176 lb 5/10/2012 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 9/15/2011 83 Male 176 lb 5/11/2012 Physician United Kingdom
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/29/2012 81 Male 199 lb 5/18/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Hyperplasia Other Serious Male 5/28/2012 Consumer United States
Primary
Concomitant
Hyperglycaemia Hospitalization 4/30/2012 75 Male 208 lb 6/1/2012 Physician France
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 4/30/2012 75 Male 208 lb 6/12/2012 Physician France
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 4/30/2012 75 Male 208 lb 6/21/2012 Physician France
Primary
Secondary
Concomitant
Neutrophil Count Increased Hospitalization 4/1/2012 59 Female 6/25/2012 Pharmacist Australia
Primary
Concomitant
Small Intestinal Obstruction Life Threatening 6/15/2012 62 Female 149 lb 7/9/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Encephalopathy Hospitalization 2/9/2012 65 Female 187 lb 2/20/2012 Pharmacist United States
Primary
Secondary
Concomitant
Abdominal Adhesions Hospitalization 6/15/2012 62 Female 149 lb 8/22/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Emphysema Other Serious Male 8/23/2012 Other Health Professional United States
Primary
Concomitant
Hypersensitivity Other Serious 8/7/2012 63 Male 201 lb 8/24/2012 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Failure Life Threatening 2/17/2012 62 Male 200 lb 9/17/2012 Other Health Professional Gb
Primary
Concomitant
Aortic Aneurysm Rupture Death Male 9/8/2012 Physician Gb
Primary
Concomitant
Dyspnoea Disability 7/30/2012 65 Male 169 lb 9/5/2012 Other Health Professional Gb
Primary
Concomitant
Dyspnoea Disability 7/30/2012 65 Male 169 lb 9/6/2012 Physician Gb
Primary
Concomitant
Dyspnoea Disability 7/30/2012 65 Male 169 lb 9/12/2012 Physician Gb
Primary
Concomitant
Hypersensitivity Other Serious 8/7/2012 63 Male 201 lb 8/31/2012 Physician Country Not Specified
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/14/2011 75 Female 119 lb 10/8/2012 Physician Gb
Primary
Concomitant
Acute Myeloid Leukaemia Hospitalization 9/17/2012 80 Male 179 lb 11/12/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Sepsis Hospitalization 11/1/2012 75 Female 11/30/2012 Other Health Professional Gb
Primary
Concomitant
Wheezing Other Serious 11/22/2012 70 Male 12/17/2012 Other Health Professional Gb
Primary
Concomitant
Insomnia Other Serious 11/19/2012 60 Male 220 lb 12/18/2012 Pharmacist Gb
Primary
Concomitant
Toxic Encephalopathy Other Serious 11/28/2012 81 Male 12/18/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Toxic Encephalopathy Hospitalization 11/28/2012 81 Male 12/27/2012 Pharmacist Gb
Primary
Secondary
Concomitant
Wheezing Disability 11/22/2012 7 Male 12/21/2012 Physician Gb
Primary
Concomitant
Toxic Encephalopathy Hospitalization 11/28/2012 81 Male 12/27/2012 Other Health Professional Gb
Primary
Secondary
Concomitant

Drug Data