Simvastatin combined with Tramadol Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Oedema Required Intervention 12/9/2005 82 Male 272 lb 1/18/2006 Pharmacist United States
Primary
Concomitant
Dizziness Other Serious 11/18/2005 76 Male 189 lb 11/18/2005 Pharmacist United States
Primary
Concomitant
Vomiting Death 1/1/2004 Female 2/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Pyrexia Hospitalization 9/24/2005 63 Male 179 lb 2/3/2006 Physician Australia
Primary
Secondary
Concomitant
Myalgia Hospitalization 11/18/2005 Male 2/21/2006 Pharmacist United States
Primary
Concomitant
Metabolic Encephalopathy Other Serious 1/1/2005 65 Male 3/6/2006 Physician Germany
Primary
Secondary
Concomitant
Hypertension Other Serious 2/15/2006 59 Male 220 lb 3/7/2006 United Kingdom
Primary
Concomitant
Angina Pectoris Other Serious 2/11/2006 49 Female 3/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Factor V Leiden Mutation Hospitalization 2/17/2006 85 Male 187 lb 3/14/2006 Pharmacist United States
Primary
Concomitant
Pruritus 11/7/2005 85 Male 141 lb 11/9/2005 United States
Primary
Concomitant
Hypertension Other Serious 2/15/2006 59 Male 220 lb 3/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonitis Hospitalization 3/27/2006 72 Male 75 lb 4/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Hospitalization 3/27/2006 72 Male 75 lb 4/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Nervous System Disorder Hospitalization 3/14/2006 77 Female 4/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 9/26/2005 71 Female 182 lb 4/13/2006 Pharmacist United States
Primary
Concomitant
Skin Disorder Hospitalization 3/27/2006 72 Male 75 lb 4/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Disorder Hospitalization 3/27/2006 72 Male 75 lb 5/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Hospitalization 2/7/2006 65 Male 157 lb 5/2/2006 Pharmacist United States
Primary
Concomitant
Skin Disorder Death 3/1/2006 42 Male 4/27/2006 Physician United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 3/17/2006 70 Male 5/10/2006 United States
Primary
Secondary
Concomitant
Convulsion Hospitalization 1/2/2006 Male 5/17/2006 Pharmacist United States
Primary
Secondary
Concomitant
Somnolence Other Serious 55 Male 5/26/2006 Consumer United Kingdom
Primary
Concomitant
Somnolence Other Serious 55 Male 6/1/2006 Consumer United Kingdom
Primary
Concomitant
Urinary Retention Other Serious 3/20/2006 74 Male 184 lb 3/27/2006 Pharmacist United States
Primary
Concomitant
Somnolence Other Serious 55 Male 6/9/2006 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 10/30/2004 55 Male 254 lb 6/12/2006 Physician United Kingdom
Primary
Concomitant
Somnolence Other Serious 55 Male 6/21/2006 Physician United Kingdom
Primary
Concomitant
Migraine Other Serious 3/10/2006 Female 155 lb 6/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Dry Mouth Other Serious 6/21/2006 56 Male 277 lb 6/28/2006 Pharmacist United States
Primary
Concomitant
Simple Partial Seizures Hospitalization 5/13/2006 57 Male 7/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Platelet Count Increased Hospitalization 7/10/2006 76 Male 181 lb 7/21/2006 Physician Australia
Primary
Secondary
Concomitant
Platelet Count Increased Other Serious 7/10/2006 76 Male 181 lb 7/21/2006 Australia
Primary
Secondary
Concomitant
Dermatitis Other Serious 7/25/2006 77 Male 226 lb 7/25/2006 Pharmacist United States
Primary
Concomitant
Syncope Other Serious 3/1/2000 Male 8/3/2006 Physician United Kingdom
Primary
Concomitant
Thinking Abnormal 5/1/2006 64 Male 200 lb 7/12/2006 Consumer United States
Primary
Concomitant
Somnolence 2/1/2006 65 Male 7/12/2006 Consumer United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 7/10/2006 76 Male 181 lb 8/15/2006 Switzerland
Primary
Secondary
Concomitant
Blood Potassium Increased Other Serious Female 8/8/2006 Other Health Professional Denmark
Primary
Concomitant
Trigeminal Neuralgia Hospitalization 1/1/2005 52 Female 220 lb 8/11/2006 Physician Germany
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 7/10/2006 76 Male 181 lb 8/18/2006 Physician Australia
Primary
Secondary
Concomitant
Small Intestinal Haemorrhage Hospitalization 6/12/2006 64 Male 198 lb 7/14/2006 Pharmacist United States
Primary
Concomitant
Thrombosis In Device Hospitalization 6/2/2006 36 Female 334 lb 8/18/2006 Other Health Professional United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/10/2005 85 Female 8/25/2006 United Kingdom
Primary
Secondary
Concomitant
Vasculitis Hospitalization 12/15/2005 Male 9/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/10/2005 85 Female 8/28/2006 United Kingdom
Primary
Secondary
Concomitant
Helicobacter Infection Hospitalization 1/10/2005 85 Female 8/28/2006 United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2000 52 Female 143 lb 8/25/2006
Primary
Secondary
Concomitant
Mitochondrial Myopathy Other Serious 52 Female 8/31/2006 Austria
Primary
Concomitant
Neck Pain Other Serious 52 Female 143 lb 9/7/2006 Physician Austria
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/6/2006 Female 163 lb 9/13/2006 Physician United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 2/1/2006 Male 9/11/2006 Pharmacist United States
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 6/19/2006 Male 9/11/2006 Pharmacist United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/1997 52 Female 143 lb 9/7/2006 Physician Austria
Primary
Concomitant
Cardiac Arrest Death 9/13/2006 53 Female 353 lb 9/21/2006 Physician Germany
Primary
Concomitant
Thinking Abnormal Death 7/23/2004 60 Male 170 lb 9/25/2006 Consumer United States
Primary
Secondary
Concomitant
Delirium Hospitalization 66 Male 9/26/2006 Physician Switzerland
Primary
Concomitant
Tremor Other Serious 7/11/2006 80 Male 163 lb 7/11/2006 Pharmacist United States
Primary
Concomitant
Thinking Abnormal Death 7/23/2004 60 Male 170 lb 10/6/2006 Consumer United States
Primary
Secondary
Concomitant
Respiratory Arrest Death 9/13/2006 53 Female 353 lb 10/18/2006 Physician Germany
Primary
Concomitant
Myocardial Ischaemia Death 8/1/2006 66 Male 187 lb 10/4/2006 United Kingdom
Primary
Concomitant
Respiratory Arrest Death 9/13/2006 53 Female 353 lb 10/26/2006 Physician Germany
Primary
Concomitant
Therapy Non-responder Hospitalization 62 Male 10/20/2006 Physician France
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 7/1/2006 57 Male 172 lb 8/11/2006 Pharmacist United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 11/21/2005 80 Male 121 lb 11/1/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 11/21/2005 80 Male 121 lb 11/2/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Respiratory Depression Hospitalization 78 Female 11/3/2006
Primary
Secondary
Concomitant
Respiratory Depression Hospitalization 78 Female 11/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Respiratory Depression Hospitalization 78 Female 11/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Therapy Non-responder Hospitalization 9/10/2006 62 Male 176 lb 10/31/2006 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 54 Female 11/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rash Erythematous Other Serious 10/6/2006 62 Female 198 lb 11/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Other Serious 84 Female 11/16/2006 Other Health Professional Brazil
Primary
Concomitant
Rash Erythematous Disability 10/6/2006 62 Female 198 lb 11/17/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tongue Disorder Hospitalization 6/1/2006 63 Male 11/9/2006 United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 11/21/2005 80 Male 11/9/2006 United Kingdom
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Other Serious 84 Female 11/21/2006 Other Health Professional Brazil
Primary
Concomitant
Vomiting Life Threatening 11/1/2005 50 Male 209 lb 11/13/2006 United States
Primary
Concomitant
Staphylococcal Infection 7/10/2006 76 Male 181 lb 11/30/2006 Switzerland
Primary
Secondary
Concomitant
Skin Reaction Other Serious 10/6/2006 62 Female 198 lb 11/27/2006 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 10/21/2006 85 Female 12/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Infection Other Serious 7/10/2006 76 Male 181 lb 11/29/2006 Physician Australia
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 10/30/2004 Male 254 lb 12/8/2006 Physician United Kingdom
Primary
Concomitant
Skin Disorder Hospitalization 3/27/2006 72 Male 75 lb 12/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/21/2006 85 Female 12/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Somnolence Hospitalization 2/1/2005 66 Male 12/14/2006 Other Health Professional United States
Primary
Concomitant
Speech Disorder Hospitalization 66 Male 12/14/2006 Physician Switzerland
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/6/2006 Female 163 lb 12/28/2006 Physician United States
Primary
Concomitant
Cerebral Infarction Hospitalization 8/13/2005 Female 139 lb 12/29/2006 United Kingdom
Primary
Concomitant
Dysgeusia 8/1/2006 48 Female 168 lb 10/11/2006 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/1997 52 Female 143 lb 1/3/2007 Physician Austria
Primary
Concomitant
Immobile Hospitalization 10/26/2006 77 Female 1/18/2007 Other Health Professional United Kingdom
Primary
Concomitant
Cerebral Infarction Hospitalization 8/13/2005 Female 139 lb 1/24/2007 United Kingdom
Primary
Concomitant
Immobile Hospitalization 10/26/2006 77 Female 1/26/2007 United Kingdom
Primary
Secondary
Concomitant
Self Esteem Decreased 7/1/2006 73 Male 11/10/2006 Consumer United States
Primary
Concomitant
Sepsis Other Serious 4/1/2005 66 Male 2/1/2007 Singapore
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 7/5/2006 152 lb 2/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Small Intestinal Perforation Hospitalization 10/16/2006 55 Female 2/15/2007 Other Health Professional Netherlands
Primary
Concomitant
Myalgia Hospitalization 12/21/2006 81 154 lb 2/12/2007 Pharmacist United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 66 Male 2/15/2007 Other Health Professional Switzerland
Primary
Concomitant
Sepsis Other Serious 4/1/2005 66 Male 3/1/2007 Singapore
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Life Threatening 2/16/2007 72 Female 3/19/2007 Physician Switzerland
Primary
Concomitant
Myositis Other Serious 2/1/2007 64 Female 220 lb 3/14/2007 United Kingdom
Primary
Secondary
Concomitant
Nausea Other Serious 2/24/2006 50 Female 12/8/2006 Other Health Professional United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/1997 52 Female 143 lb 3/13/2007 Physician Austria
Primary
Concomitant
Weight Increased Other Serious 42 Male 11/13/2006 Physician United States
Primary
Concomitant
Pain Hospitalization 2/15/2007 85 Female 99 lb 3/23/2007 United Kingdom
Primary
Concomitant
Renal Artery Stenosis Other Serious 3/3/2006 75 Male 198 lb 4/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/9/2007 79 Female 4/4/2007 Physician
Primary
Secondary
Concomitant
Myositis Other Serious 2/16/2007 66 Male 3/28/2007 United Kingdom
Primary
Concomitant
Speech Disorder Hospitalization 11/1/2006 43 Female 179 lb 4/9/2007 Physician United Kingdom
Primary
Concomitant
Muscle Spasms Other Serious 2/1/2007 59 Female 3/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Blood Glucose Increased Other Serious 2/5/2007 39 Female 140 lb 4/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Life Threatening 2/16/2007 72 Female 4/10/2007 Physician Switzerland
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/9/2007 79 Female 4/7/2007 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/22/2007 Female 170 lb 3/30/2007 Pharmacist United States
Primary
Concomitant
Rash Hospitalization 6/6/2006 Female 163 lb 4/18/2007 Physician United States
Primary
Concomitant
Nausea Hospitalization 3/26/2007 Female 172 lb 4/19/2007
Primary
Concomitant
Renal Artery Stenosis Other Serious 3/3/2006 75 Male 198 lb 4/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Required Intervention 3/6/2007 62 4/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2004 Female 5/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Respiratory Depression Other Serious 78 Female 5/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Breast Cancer Hospitalization 2/23/2007 68 Female 251 lb 5/2/2007 Physician United Kingdom
Primary
Concomitant
Respiratory Depression Other Serious 78 Female 5/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Small Intestinal Perforation Hospitalization 10/16/2006 55 Female 5/7/2007 Other Health Professional Netherlands
Primary
Concomitant
Sepsis Other Serious 4/1/2005 76 Male 4/27/2007 Singapore
Primary
Concomitant
Vomiting Other Serious 4/1/2007 45 Female 4/26/2007 United States
Primary
Concomitant
Rash Hospitalization 6/6/2006 Female 163 lb 5/17/2007 Physician United States
Primary
Concomitant
Vision Blurred Hospitalization 45 Male 201 lb 5/14/2007 Physician United Kingdom
Primary
Concomitant
Tremor Other Serious 5/9/2007 66 Female 5/22/2007 Consumer Brazil
Primary
Concomitant
Faecaloma Hospitalization 4/20/2007 Male 160 lb 5/23/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 54 Female 5/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Spleen Disorder Death 1/8/2004 79 Female 5/24/2007 Physician
Primary
Concomitant
Spleen Disorder Hospitalization 79 Female 5/24/2007 United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 5/9/2007 66 Female 6/8/2007 Consumer Brazil
Primary
Concomitant
Vomiting Other Serious 1/1/2007 67 Male 251 lb 6/15/2007 Physician United Kingdom
Primary
Concomitant
Bladder Cancer Other Serious 3/29/2007 Male 170 lb 6/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Hypertrophy Hospitalization Female 7/3/2007 Physician United Kingdom
Primary
Concomitant
Wound Dehiscence Hospitalization 3/8/2007 Female 143 lb 7/9/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Male 7/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 7/5/2006 Male 152 lb 7/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Dizziness 73 Female 7/23/2007 Consumer United States
Primary
Concomitant
Muscular Weakness Hospitalization 6/9/2007 83 Female 7/27/2007 United Kingdom
Primary
Concomitant
Muscular Weakness Hospitalization 6/9/2007 83 Female 132 lb 7/27/2007 United Kingdom
Primary
Concomitant
Muscular Weakness Hospitalization 6/9/2007 83 Female 7/25/2007 United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 7/18/2006 Female 8/3/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 6/9/2007 83 Female 132 lb 8/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Myoclonus Disability 5/16/2007 56 Female 8/10/2007
Primary
Secondary
Concomitant
Tremor Other Serious 8/11/2006 82 Male 8/10/2007 Physician United Kingdom
Primary
Concomitant
Nausea Other Serious 2/24/2006 50 Female 196 lb 6/8/2007 Other Health Professional United States
Primary
Concomitant
Tremor Hospitalization 8/1/2006 55 Female 8/18/2007 Pharmacist United States
Primary
Secondary
Concomitant

Drug Data