Diclofenac Sodium combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pyrexia Hospitalization 9/24/2005 63 Male 179 lb 2/3/2006 Physician Australia
Primary
Secondary
Concomitant
Tachycardia Other Serious 1/1/2004 64 Male 203 lb 2/10/2006 Physician Switzerland
Primary
Secondary
Concomitant
Pneumonia Hospitalization Female 2/10/2006 United Kingdom
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 2/1/2006 64 Female 161 lb 3/2/2006 Physician Germany
Primary
Secondary
Concomitant
Vomiting Life Threatening 2/13/2006 57 Male 3/29/2006 Physician United Kingdom
Primary
Concomitant
Sepsis Hospitalization Female 4/6/2006 Consumer United Kingdom
Primary
Concomitant
Renal Impairment Life Threatening 2/13/2006 57 Male 3/29/2006 Physician United Kingdom
Primary
Concomitant
Thalamic Infarction Other Serious 2/1/2006 Female 151 lb 4/14/2006 Physician Germany
Primary
Concomitant
Vitreous Haemorrhage Other Serious 2/9/2003 84 Male 4/20/2006 United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 70 Female 5/18/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Sepsis Hospitalization 12/29/2005 Female 8/2/2006 Consumer United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 6/10/2006 Male 8/10/2006 Other Health Professional United Kingdom
Primary
Concomitant
Duodenal Ulcer Perforation Other Serious 3/4/2006 69 Female 8/8/2006 Denmark
Primary
Concomitant
Weight Decreased Hospitalization 6/10/2006 Male 8/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pain Other Serious 1/1/2003 54 Female 10/31/2006 Norway
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 9/1/2006 Female 11/7/2006 United States
Primary
Concomitant
Rash Erythematous Disability 10/6/2006 62 Female 198 lb 11/17/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 70 Female 11/21/2006
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 70 Female 11/22/2006
Primary
Concomitant
Interacting
Haemorrhage Hospitalization 6/15/2006 90 Male 11/13/2006 United Kingdom
Primary
Concomitant
Skin Reaction Other Serious 10/6/2006 62 Female 198 lb 11/27/2006 United Kingdom
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 10/30/2004 Male 254 lb 12/8/2006 Physician United Kingdom
Primary
Concomitant
Urine Ketone Body Present Other Serious 12/1/2005 Female 12/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Cerebral Infarction Hospitalization 8/13/2005 Female 139 lb 12/29/2006 United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 10/29/2006 59 Male 287 lb 12/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 7/6/2006 68 Female 1/5/2007 Physician Germany
Primary
Concomitant
Joint Swelling Hospitalization 7/15/2006 Female 159 lb 1/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Nausea Hospitalization 7/7/2006 84 Male 134 lb 10/26/2006 Pharmacist United States
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 8/13/2005 Female 139 lb 1/24/2007 United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 5/18/2006 Male 190 lb 1/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Stent Placement Life Threatening 6/18/2006 60 Male 202 lb 1/19/2007 Physician United States
Primary
Concomitant
No Adverse Effect 6/1/2006 69 Male 1/29/2007 Physician United Kingdom
Primary
Concomitant
Vitreous Haemorrhage Required Intervention 2/9/2003 83 Male 1/30/2007 United Kingdom
Primary
Concomitant
Loss Of Consciousness Other Serious 12/14/2005 Female 201 lb 2/9/2007 Physician United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 6/10/2006 Male 2/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Plasma Cells Increased Other Serious 12/1/2006 74 Male 2/13/2007 Physician United States
Primary
Secondary
Concomitant
Plasma Cells Increased Other Serious 12/1/2006 74 Male 2/28/2007 Physician United States
Primary
Secondary
Concomitant
Vitreous Haemorrhage Other Serious 83 Male 3/5/2007 United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 12/14/2005 Female 201 lb 3/14/2007 Physician United Kingdom
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 2/13/2007 54 Male 3/14/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 10/10/2006 Male 190 lb 3/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 6/10/2006 Male 3/28/2007 Physician United Kingdom
Primary
Concomitant
Mineral Deficiency Other Serious 9/1/2006 65 Female 184 lb 3/29/2007 Consumer United Kingdom
Primary
Concomitant
Rash Generalised Hospitalization 11/24/2006 89 Male 4/6/2007 United Kingdom
Primary
Secondary
Concomitant
Swelling Hospitalization 11/24/2006 89 Male 187 lb 4/3/2007 United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 11/24/2006 89 Male 3/29/2007 United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious 6/1/2006 73 Female 3/27/2007 United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 11/24/2006 89 Male 187 lb 4/3/2007 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 6/10/2006 Male 4/27/2007 Physician United Kingdom
Primary
Concomitant
Osteoarthritis Required Intervention 9/13/2006 71 Male 231 lb 4/26/2007 Germany
Primary
Concomitant
Hallucination Other Serious 3/24/2007 79 Female 117 lb 6/7/2007 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 3/1/2007 53 Female 141 lb 6/15/2007 Pharmacist Germany
Primary
Concomitant
Osteoarthritis Required Intervention 4/1/2006 71 Male 231 lb 4/26/2007 Consumer Germany
Primary
Concomitant
Pulmonary Oedema Other Serious 6/1/2006 71 Male 229 lb 6/20/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Paraesthesia Other Serious 6/10/2007 69 Female 168 lb 7/9/2007 United Kingdom
Primary
Concomitant
Synovitis Hospitalization 7/15/2006 Female 159 lb 7/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 1/1/1997 Female 7/20/2007 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Musculoskeletal Chest Pain Hospitalization 11/15/2006 Female 269 lb 7/27/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Musculoskeletal Chest Pain Hospitalization 12/5/2006 Female 269 lb 7/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 3/1/2006 Male 183 lb 9/10/2007 United Kingdom
Primary
Concomitant
Tachyarrhythmia Life Threatening 1/1/2007 63 Male 216 lb 10/11/2007 Physician Germany
Primary
Concomitant
Pleurisy Hospitalization 5/9/2007 Male 214 lb 10/11/2007 United Kingdom
Primary
Concomitant
Serotonin Syndrome Required Intervention 7/23/2007 60 Female 183 lb 10/28/2007 Other Health Professional United States
Primary
Concomitant
Muscle Spasms Other Serious 9/20/2007 11/5/2007 Consumer United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 6/10/2006 Male 12/21/2007 Physician United Kingdom
Primary
Concomitant
Motor Dysfunction Disability 11/6/2007 71 Female 12/31/2007 Other Health Professional United Kingdom
Primary
Concomitant
Swelling Face Other Serious 11/22/2007 63 Female 143 lb 12/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective 8/1/2007 69 Male 1/9/2008 Consumer United States
Primary
Concomitant
Serotonin Syndrome Other Serious 7/23/2007 Female 183 lb 1/24/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Male 2/13/2008 Other Health Professional Netherlands
Primary
Concomitant
Urticaria Disability 68 Female 132 lb 2/19/2008 United Kingdom
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Other Serious 11/29/2007 46 Female 2/21/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Hypothermia Other Serious 10/16/2007 Male 121 lb 2/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Swollen Tongue Other Serious 2/13/2008 Female 174 lb 2/26/2008 Consumer United States
Primary
Concomitant
Urticaria Disability 68 Female 2/15/2008 United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2007 Female 162 lb 10/15/2007 Pharmacist United States
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 9/4/2007 Female 2/28/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Productive Cough Other Serious 1/31/2008 71 Male 176 lb 2/29/2008 Physician United Kingdom
Primary
Concomitant
Urine Output Decreased Other Serious 70 Female 154 lb 3/1/2008 United Kingdom
Primary
Concomitant
Hyperkalaemia Hospitalization 9/4/2007 3/5/2008 Consumer Canada
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Other Serious 1/31/2008 71 Male 176 lb 3/1/2008 United Kingdom
Primary
Concomitant
Stent Occlusion Hospitalization 2/28/2008 69 Female 3/6/2008 Other Health Professional United States
Primary
Concomitant
Urticaria Other Serious 68 Female 132 lb 3/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 70 Female 154 lb 3/9/2008 United Kingdom
Primary
Concomitant
Orthostatic Hypotension Other Serious 1/31/2008 3/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Male 3/11/2008 Other Health Professional Netherlands
Primary
Concomitant
Glossodynia Hospitalization 3/3/2008 56 Female 3/27/2008 France
Primary
Concomitant
Glossodynia Other Serious 3/3/2008 56 Female 4/4/2008 France
Primary
Concomitant
Glossodynia Other Serious 3/3/2008 Female 4/17/2008 France
Primary
Concomitant
Cerebral Infarction Hospitalization 8/13/2005 Female 139 lb 4/25/2008 United Kingdom
Primary
Concomitant
Tachypnoea Death 63 Male 5/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Other Serious 11/29/2007 46 Female 6/6/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Oedema Peripheral Other Serious 3/5/2008 70 Female 190 lb 6/20/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 195 lb 6/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
Tracheal Haemorrhage Hospitalization 63 Male 6/16/2008
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/14/2007 Female 172 lb 6/25/2008 United Kingdom
Primary
Concomitant
Vaginal Haemorrhage Other Serious 4/10/2005 50 Female 6/26/2008 Other Health Professional Venezuela
Primary
Secondary
Concomitant
Panic Attack Hospitalization 1/1/2007 Male 230 lb 7/1/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 2/26/2008 Male 248 lb 7/7/2008 Consumer United Kingdom
Primary
Concomitant
Somnolence 4/1/2007 66 Female 7/24/2008 Consumer United States
Primary
Concomitant
Hepatic Cyst Hospitalization 4/25/2008 Female 187 lb 7/24/2008 United Kingdom
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/1999 Male 7/28/2008 Physician United Kingdom
Primary
Concomitant
Loss Of Consciousness Other Serious 7/8/2008 67 Male 140 lb 7/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Tachyarrhythmia Hospitalization 3/10/2008 75 Female 7/29/2008 Other Health Professional Germany
Primary
Concomitant
Prostate Cancer Hospitalization 3/23/2005 76 Male 187 lb 7/28/2008 United Kingdom
Primary
Concomitant
Interacting
International Normalised Ratio Increased 9/20/2007 68 Male 7/29/2008 Consumer United States
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 7/7/2008 Female 125 lb 8/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 7/8/2008 67 Male 140 lb 7/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Prostate Cancer Hospitalization 3/23/2005 76 Male 187 lb 8/1/2008 United Kingdom
Primary
Concomitant
Interacting
Syncope Hospitalization 3/23/2005 76 Male 187 lb 8/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/23/2005 76 Male 187 lb 8/8/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 3/15/2008 Male 245 lb 8/11/2008 United Kingdom
Primary
Concomitant
Prostate Cancer Hospitalization 76 Male 8/1/2008 United Kingdom
Primary
Secondary
Concomitant
Musculoskeletal Pain Other Serious 3/4/2006 69 Female 10/22/2008 Denmark
Primary
Concomitant
Vitreous Haemorrhage Required Intervention 2/9/2003 84 Male 10/22/2008 Denmark
Primary
Concomitant
Gastric Ulcer Perforation Other Serious 6/6/2006 48 Female 10/22/2008 Denmark
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2007 Male 10/31/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/11/2003 47 Female 260 lb 11/10/2008 United States
Primary
Concomitant
Alopecia Other Serious 9/4/2008 38 Female 11/11/2008 Other Health Professional United Kingdom
Primary
Concomitant
Encephalopathy Hospitalization 8/7/2008 Female 286 lb 11/18/2008 United States
Primary
Secondary
Concomitant
Stress Fracture Hospitalization 64 Female 11/19/2008 Netherlands
Primary
Concomitant
Hypoglycaemic Unconsciousness Other Serious 12/14/2005 Female 201 lb 11/25/2008 Physician United Kingdom
Primary
Concomitant
Ventricular Tachycardia Other Serious 6/13/2008 Female 12/2/2008 Pharmacist United Kingdom
Primary
Concomitant
Osteonecrosis Other Serious 7/1/2007 82 Female 11/26/2008 Physician United States
Primary
Concomitant
Skin Laceration 72 Female 12/16/2008 Consumer United States
Primary
Concomitant
Encephalopathy Hospitalization 7/7/2008 Female 286 lb 12/22/2008 Physician United States
Primary
Secondary
Concomitant
Encephalopathy Hospitalization 7/7/2008 Female 286 lb 1/5/2009 Physician United States
Primary
Secondary
Concomitant
Tremor Hospitalization 11/3/2005 Female 1/12/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Acute Myocardial Infarction Life Threatening 12/2/2008 1/28/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 12/21/2008 82 Male 1/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 2/10/2009 Pharmacist United Kingdom
Primary
Secondary
International Normalised Ratio Increased Hospitalization 2/25/2009 Other Health Professional United Kingdom
Primary
Secondary
Agranulocytosis Other Serious 11/5/2008 Female 176 lb 2/19/2009 Physician Germany
Primary
Secondary
Concomitant
Lung Disorder Other Serious 1/16/2009 Female 3/11/2009 Physician United Kingdom
Primary
Concomitant
Pulmonary Thrombosis Other Serious 9/1/2008 Male 215 lb 3/26/2009 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 3/31/2009 Other Health Professional United Kingdom
Primary
Secondary
Lung Disorder Other Serious 1/16/2009 Female 4/8/2009 Physician United Kingdom
Primary
Concomitant
Pulmonary Thrombosis Other Serious 9/1/2008 Male 215 lb 4/9/2009 Consumer United States
Primary
Concomitant
Death Death Female 4/15/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 3/9/2009 4/17/2009 Pharmacist Netherlands
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 3/9/2009 Male 176 lb 4/16/2009 Pharmacist Netherlands
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 1/1/1998 51 Male 214 lb 5/20/2009 United States
Primary
Concomitant
General Physical Health Deterioration Hospitalization 5/4/2009 Male 5/22/2009 Physician United Kingdom
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 5/4/2009 Male 5/28/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting 4/21/2009 Male 235 lb 5/29/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 7/8/2008 67 Male 140 lb 5/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 7/8/2008 67 Male 140 lb 5/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Administered At Inappropriate Site 4/1/2009 Female 245 lb 6/2/2009 Consumer United States
Primary
Concomitant
Staphylococcal Infection Other Serious 2/16/2009 Male 222 lb 6/3/2009 Consumer United Kingdom
Primary
Concomitant
Loss Of Consciousness Other Serious 7/8/2008 67 Male 140 lb 6/3/2009 Other Health Professional United Kingdom
Primary
Secondary

Drug Data