Metoprolol Tartrate combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Coronary Artery Disease Hospitalization 5/1/2005 56 Male 1/5/2006 Consumer United States
Primary
Concomitant
Pleural Disorder Other Serious 9/21/2005 57 Male 216 lb 1/10/2006 Netherlands
Primary
Secondary
Concomitant
Stent Occlusion Hospitalization 7/25/2005 64 Male 183 lb 1/12/2006 Poland
Primary
Secondary
Concomitant
Quadruple Vessel Bypass Graft Hospitalization 5/1/2005 56 Male 1/20/2006 Consumer United States
Primary
Concomitant
Pleural Disorder Other Serious 9/21/2005 57 Male 216 lb 1/10/2006 Netherlands
Primary
Secondary
Concomitant
Fat Tissue Increased Hospitalization 12/15/2003 53 Female 1/25/2006 Netherlands
Primary
Concomitant
Hypersensitivity Required Intervention 11/14/2005 79 Male 208 lb 11/16/2005 Pharmacist United States
Primary
Concomitant
Dizziness Other Serious 11/18/2005 76 Male 189 lb 11/18/2005 Pharmacist United States
Primary
Concomitant
Lethargy Other Serious 12/27/2005 64 Female 253 lb 12/30/2005 Pharmacist United States
Primary
Concomitant
Venous Thrombosis Other Serious 11/11/2004 Male 225 lb 2/7/2006 Physician United States
Primary
Concomitant
Faeces Discoloured Hospitalization 10/24/2005 72 Male 296 lb 10/25/2005 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/1/2005 82 Male 172 lb 11/1/2005 Pharmacist United States
Primary
Concomitant
Tachycardia Other Serious 1/1/2004 64 Male 203 lb 2/10/2006 Physician Switzerland
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 11/13/2005 Male 171 lb 11/18/2005 Pharmacist United States
Primary
Secondary
Concomitant
Syncope Hospitalization 10/14/2005 63 Male 359 lb 12/2/2005 Pharmacist United States
Primary
Secondary
Concomitant
Radiculopathy Hospitalization 11/1/2003 Male 231 lb 2/15/2006 Physician New Zealand
Primary
Concomitant
Vertigo Other Serious 1/17/2002 72 Male 198 lb 2/17/2006 Physician United States
Primary
Concomitant
Myalgia Other Serious 1/31/2006 61 Male 233 lb 1/31/2006 Pharmacist United States
Primary
Concomitant
Nonspecific Reaction Other Serious 12/9/2005 55 Male 211 lb 1/31/2006 Pharmacist United States
Primary
Concomitant
Ulcer Haemorrhage Life Threatening 7/18/2003 61 Male 2/23/2006 Other Health Professional Norway
Primary
Concomitant
Coma Death 3/15/2004 77 Male 2/15/2006 United Kingdom
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Hospitalization 8/29/2004 75 Female 170 lb 12/29/2005 Other Health Professional United States
Primary
Concomitant
Vitreous Haemorrhage Hospitalization 7/18/2002 49 Male 12/29/2005 United States
Primary
Secondary
Concomitant
Respiratory Disorder Hospitalization 10/1/2004 58 Male 184 lb 12/21/2005 Physician United States
Primary
Concomitant
Hyperhidrosis Hospitalization 3/18/2006 67 Male 230 lb 3/22/2006 Pharmacist United States
Primary
Concomitant
Swollen Tongue Other Serious 2/12/2006 71 Male 3/9/2006 Consumer United Kingdom
Primary
Concomitant
Pneumonitis Hospitalization 3/27/2006 72 Male 75 lb 4/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Coronary Artery Stenosis Hospitalization 10/4/2005 70 Male 159 lb 3/31/2006 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Wound Infection Hospitalization 3/27/2006 72 Male 75 lb 4/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Gait Disturbance 1/18/2006 61 Male 4/7/2006 Pharmacist United States
Primary
Concomitant
Myalgia Other Serious 8/4/2005 73 Male 209 lb 4/13/2006 Physician United States
Primary
Concomitant
Myalgia Other Serious 7/22/2005 51 Male 227 lb 4/13/2006 Pharmacist United States
Primary
Concomitant
Skin Disorder Hospitalization 3/27/2006 72 Male 75 lb 4/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rhinorrhoea Other Serious 12/19/2005 67 Male 235 lb 4/14/2006 Pharmacist United States
Primary
Concomitant
Hypoaesthesia Other Serious 1/6/2006 88 Male 182 lb 4/14/2006 Pharmacist United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 2/9/2003 84 Male 4/20/2006 United Kingdom
Primary
Secondary
Concomitant
Respiratory Rate Increased Hospitalization 4/14/2006 84 Male 165 lb 4/19/2006 Pharmacist United States
Primary
Concomitant
Myalgia Other Serious 3/2/2006 64 Male 180 lb 3/2/2006 Pharmacist United States
Primary
Concomitant
Postoperative Infection Hospitalization 5/14/2003 51 Male 4/27/2006 Norway
Primary
Concomitant
Tachycardia Hospitalization 12/1/2001 63 Male 4/28/2006 Norway
Primary
Concomitant
Skin Disorder Hospitalization 3/27/2006 72 Male 75 lb 5/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 11/8/2005 71 Male 143 lb 5/1/2006 Poland
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 2/26/2006 Male 258 lb 5/2/2006 Pharmacist United States
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 2/27/2006 Male 258 lb 5/2/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 3/1/2004 60 Male 181 lb 5/9/2006 Physician Canada
Primary
Concomitant
Vision Blurred Hospitalization 4/29/2006 84 Male 172 lb 5/9/2006 Pharmacist United States
Primary
Secondary
Concomitant
Rash Maculo-papular Required Intervention 9/24/2005 76 Female 159 lb United States
Primary
Concomitant
Chest Pain Life Threatening 2/16/2006 84 Female 2/17/2006 Pharmacist United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 3/1/2004 60 Male 181 lb 5/12/2006 Physician Canada
Primary
Concomitant
Rhabdomyolysis Life Threatening 2/23/2006 Male 5/16/2006 Pharmacist United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Hospitalization 1/16/2006 Male 5/16/2006 Pharmacist United States
Primary
Concomitant
Loss Of Consciousness Life Threatening 4/6/2006 61 Male 213 lb 5/19/2006 Other Health Professional Puerto Rico
Primary
Secondary
Concomitant
Vascular Pseudoaneurysm Hospitalization 3/27/2006 Male 5/17/2006 Pharmacist United States
Primary
Concomitant
Hallucination 1/17/2006 Male 121 lb 5/18/2006 Pharmacist United States
Primary
Concomitant
Convulsion Hospitalization 1/2/2006 Male 5/17/2006 Pharmacist United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 5/21/2006 77 Male 211 lb 5/25/2006 Pharmacist United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 4/19/2006 Male 148 lb 5/31/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Initial Insomnia 2/17/2006 81 Male 215 lb 4/3/2006 Consumer United States
Primary
Concomitant
Drug Effect Decreased 1/1/2006 80 Male 150 lb 4/3/2006 Consumer United States
Primary
Concomitant
Middle Insomnia 11/29/2005 76 Male 185 lb 4/3/2006 Consumer United States
Primary
Concomitant
Non-cardiac Chest Pain Hospitalization 9/20/2005 48 Male 161 lb 5/30/2006 United Kingdom
Primary
Secondary
Concomitant
Thrombosis Other Serious 56 Male 290 lb 6/2/2006 Pharmacist United States
Primary
Concomitant
Rash Erythematous Other Serious 12/13/2005 Male 164 lb 3/3/2006 Physician United States
Primary
Concomitant
Angioneurotic Oedema Required Intervention 6/2/2006 62 Male 158 lb 6/13/2006 Pharmacist United States
Primary
Concomitant
Rash Required Intervention 2/6/2006 48 Male 208 lb 3/6/2006 Pharmacist United States
Primary
Concomitant
Hypotension Required Intervention 6/8/2006 80 Male 201 lb 6/8/2006 Pharmacist United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 11/8/2005 71 Male 143 lb 6/12/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Haematoma Hospitalization 5/17/2006 50 Female 176 lb 6/12/2006 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 4/19/2006 79 Male 148 lb 6/12/2006 United States
Primary
Secondary
Concomitant
Nausea 6/7/2006 58 Male 160 lb 6/15/2006 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Other Serious 6/14/2006 47 Male 297 lb 6/19/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Death 3/23/2006 Male 154 lb 6/23/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Hospitalization 6/9/2006 75 Male 251 lb 6/26/2006 Consumer United States
Primary
Concomitant
Oral Intake Reduced Hospitalization 12/5/2005 61 Female 6/16/2006 Physician Netherlands
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 80 Female 6/29/2006 Other Health Professional Australia
Primary
Concomitant
Nausea Hospitalization 5/1/2006 60 Male 128 lb 5/4/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Death 6/28/2006 58 Male 172 lb 6/29/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Other Serious 3/3/2006 66 Female 6/20/2006 Canada
Primary
Concomitant
Coronary Artery Stenosis Hospitalization 12/13/2005 55 Male 6/27/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
International Normalised Ratio Fluctuation Other Serious 54 Male 143 lb 7/6/2006 Other Health Professional United States
Primary
Concomitant
Interacting
Ventricular Fibrillation Life Threatening 4/19/2006 79 Male 148 lb 6/28/2006 United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 4/13/2006 67 Male 6/29/2006 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 4/24/2006 67 Male 7/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 6/23/2006 57 Male 192 lb 7/4/2006 Pharmacist United States
Primary
Concomitant
Simple Partial Seizures Hospitalization 5/13/2006 57 Male 7/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vision Blurred Disability 1/23/2006 Male 184 lb 6/26/2006 Pharmacist United States
Primary
Concomitant
Wheezing Hospitalization 5/1/2006 37 Male 260 lb 7/7/2006 Pharmacist United States
Primary
Concomitant
Lethargy Hospitalization 5/5/2006 70 Male 7/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Fluctuation Other Serious 54 Male 143 lb 6/30/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 5/10/2006 Male 150 lb 7/13/2006 Physician United Kingdom
Primary
Concomitant
Urticaria Other Serious 8/26/2005 76 Male 176 lb 7/17/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Post Procedural Complication Hospitalization 9/1/2005 39 Male 7/10/2006 Norway
Primary
Secondary
Concomitant
Perinephric Effusion Other Serious 1/1/2003 49 Male 7/6/2006 Physician United States
Primary
Concomitant
Rash Hospitalization 5/29/2006 81 Male 243 lb 7/14/2006 Pharmacist United States
Primary
Concomitant
Hyperthyroidism Hospitalization 12/1/2005 43 Male 168 lb 7/14/2006 United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 7/20/2006 Other Health Professional Sweden
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 11/8/2005 71 Male 143 lb 7/18/2006 Physician Poland
Primary
Secondary
Concomitant
Prostate Cancer Hospitalization 5/15/2006 66 Male 237 lb 7/17/2006 Physician United States
Primary
Concomitant
Hyperhidrosis Required Intervention 7/11/2006 54 Male 165 lb 7/19/2006 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 4/27/2006 72 Male 177 lb 5/15/2006 Pharmacist United States
Primary
Secondary
Concomitant
Bradycardia Hospitalization 6/5/2006 71 Male Pharmacist United States
Primary
Concomitant
Heart Rate Irregular Hospitalization 5/21/2006 64 Male 224 lb 5/23/2006 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 1/1/2001 59 Female 7/20/2006 Czech Republic
Primary
Concomitant
Insomnia 6/9/2006 82 Female 106 lb 7/12/2006 Consumer United States
Primary
Concomitant
Dizziness 3/1/2006 85 Male 175 lb 7/12/2006 Consumer United States
Primary
Concomitant
Supraventricular Tachycardia Other Serious 3/3/2006 66 Female 7/21/2006 Canada
Primary
Concomitant
Thrombocytopenia Hospitalization 7/19/2006 77 Male 8/3/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Sinus Operation Hospitalization 9/1/2005 39 Male 7/28/2006 Norway
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 8/4/2006 Other Health Professional Sweden
Primary
Concomitant
Therapeutic Response Decreased 11/1/2005 Male 143 lb 8/9/2006 Physician United States
Primary
Concomitant
Hypotension Hospitalization 6/27/2006 62 Male 8/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 4/17/2000 77 Male 8/15/2006 France
Primary
Concomitant
Myocardial Infarction Hospitalization 12/14/2000 72 Female 8/15/2006 France
Primary
Concomitant
Myocardial Ischaemia Hospitalization 3/30/2000 70 Male 8/15/2006 France
Primary
Concomitant
Coronary Artery Disease Hospitalization 9/9/2001 71 Male 176 lb 8/15/2006 France
Primary
Concomitant
Subdural Haematoma Hospitalization 12/27/2005 44 Female 8/9/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/25/2006 67 Male 8/18/2006 Physician United Kingdom
Primary
Concomitant
Nightmare 5/1/2006 Male 500 lb 8/16/2006 Pharmacist United States
Primary
Concomitant
Supraventricular Tachycardia Other Serious 3/3/2006 66 Female 8/11/2006 Canada
Primary
Concomitant
Ventricular Fibrillation Life Threatening 4/19/2006 79 Male 148 lb 8/16/2006 United Kingdom
Primary
Secondary
Concomitant
Hyperthyroidism Hospitalization 12/1/2005 43 Male 168 lb 8/16/2006 Poland
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/25/2006 52 Male 198 lb 8/16/2006 Romania
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/25/2006 52 Male 198 lb 8/17/2006 Other Health Professional Romania
Primary
Secondary
Concomitant
Neoplasm Progression Life Threatening 6/2/2006 Male 8/23/2006
Primary
Concomitant
Retching Hospitalization 5/14/2006 74 Male 243 lb 6/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 5/13/2006 49 Male 250 lb 6/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization Male 159 lb 6/20/2006 Pharmacist United States
Primary
Secondary
Concomitant
Anaphylactic Reaction Other Serious 8/3/2006 76 Male 8/25/2006 Pharmacist United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 8/25/2006 Other Health Professional Sweden
Primary
Concomitant
Neoplasm Progression Life Threatening 6/2/2006 Male 8/30/2006
Primary
Secondary
Concomitant
Sedation 2/1/2006 83 Male 9/6/2006 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 9/8/2006 Other Health Professional Sweden
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 9/8/2006 Other Health Professional Sweden
Primary
Concomitant
Nausea Other Serious 4/3/2006 Female 9/6/2006 United Kingdom
Primary
Concomitant
Glycogen Storage Disease Type V Other Serious 62 Male 9/7/2006 Greece
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/6/2006 Female 163 lb 9/13/2006 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 5/22/2006 60 Male 9/8/2006 Netherlands
Primary
Concomitant
Ultrasound Abdomen Abnormal Other Serious 70 Male 9/12/2006 Physician Switzerland
Primary
Concomitant
Ventricular Hypertrophy Other Serious 7/25/2006 52 Male 198 lb 9/20/2006 United States
Primary
Secondary
Concomitant
Coronary Artery Thrombosis Hospitalization 8/21/2006 57 Male 176 lb 9/20/2006 United States
Primary
Secondary
Concomitant
Post Procedural Haematoma Hospitalization 5/8/2006 65 Female 154 lb 9/20/2006 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 4/25/2006 Male 203 lb 4/26/2006 Pharmacist United States
Primary
Concomitant
Post Procedural Complication Hospitalization 9/12/2006 68 Male 173 lb 9/21/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pruritus Required Intervention 9/21/2006 64 Male 171 lb 9/21/2006 Pharmacist United States
Primary
Concomitant
Rash Generalised Other Serious 9/15/2006 53 Male 172 lb 9/25/2006 Other Health Professional United States
Primary
Concomitant
Blood Lactic Acid Increased Other Serious 7/11/2006 63 Male 250 lb 7/13/2006 Pharmacist United States
Primary
Concomitant
Coronary Artery Stenosis Hospitalization 5/8/2006 65 Female 154 lb 9/13/2006 United States
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Other Serious 11/2/2005 63 Male 189 lb 9/28/2006 Pharmacist United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 1/24/2006 Male 176 lb 10/5/2006 Other Health Professional United States
Primary
Concomitant
Red Blood Cell Count Decreased Hospitalization 5/23/2006 73 Male 176 lb 10/3/2006 Poland
Primary
Secondary
Concomitant

Drug Data