Lactulose combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Breast Cancer Stage Iii Hospitalization 9/19/2005 Female 1/5/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rales Life Threatening 11/11/2005 85 Female 1/23/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 1/12/2006 76 Male 2/14/2006 Physician Netherlands
Primary
Concomitant
Haemorrhage Hospitalization 9/5/2005 85 Female 100 lb 11/21/2005 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 2/24/2006 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 3/2/2006 Physician United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Other Serious 9/1/2001 70 Female 126 lb 4/14/2006 Physician Canada
Primary
Concomitant
Weight Decreased Life Threatening 11/1/2005 Male 4/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 6/22/2005 45 Female 150 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2005 Male 5/15/2006 Physician Canada
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 3/1/2006 61 Male 5/19/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Muscle Haemorrhage Hospitalization 10/1/2004 74 Female 123 lb 5/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Disorder Other Serious 1/16/2006 60 Female 6/8/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/14/2006 Male 157 lb 6/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Cerebrovascular Accident Death Male 157 lb 6/21/2006 Consumer United Kingdom
Primary
Concomitant
Hypotension Hospitalization 6/22/2006 86 Male 220 lb 7/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 10/3/2005 42 Male 1/25/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/26/2005 53 Female 132 lb 2/8/2006 United States
Primary
Concomitant
Urinary Retention Other Serious 6/12/2006 56 Male 162 lb 6/12/2006 Pharmacist United States
Primary
Concomitant
Pneumonia Hospitalization 8/29/2006 70 Female 9/18/2006 Physician Sweden
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 5/11/2006 79 Female 154 lb 10/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 79 Female 154 lb 9/29/2006 United Kingdom
Primary
Concomitant
Tremor Hospitalization 8/28/2006 Male 10/23/2006 Pharmacist United States
Primary
Concomitant
Sarcoidosis Other Serious 4/1/2004 69 Female 10/26/2006 United Kingdom
Primary
Concomitant
Hypercholesterolaemia Death Male 157 lb 11/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Platelet Count Decreased Hospitalization 6/8/2006 81 Female 11/7/2006 Consumer United Kingdom
Primary
Concomitant
Tremor Hospitalization 10/20/2006 64 Male 131 lb 11/3/2006 Other Health Professional United States
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 8/7/2006 85 Female 164 lb 11/11/2006 Physician Germany
Primary
Concomitant
Skin Lesion Other Serious 7/23/2006 72 Female 11/10/2006 United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/20/2006 64 Male 131 lb 11/10/2006 Other Health Professional United States
Primary
Concomitant
Gout Disability 3/1/2006 86 Female 120 lb 12/5/2006 United Kingdom
Primary
Concomitant
Hyponatraemia Hospitalization 8/29/2006 76 Female 12/6/2006
Primary
Secondary
Concomitant
Vomiting Other Serious 10/21/2006 85 Female 12/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Hospitalization 10/20/2006 64 Male 131 lb 11/29/2006 Other Health Professional United States
Primary
Concomitant
Neutropenia Required Intervention 9/6/2006 75 Male 144 lb 10/2/2006 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 10/20/2006 64 Male 132 lb 12/6/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 10/21/2006 85 Female 12/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Hospitalization 10/20/2006 64 Male 132 lb 12/13/2006 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Hospitalization 10/20/2006 Male 129 lb 1/2/2007 United States
Primary
Concomitant
Urticaria Other Serious 7/23/2006 72 Female 154 lb 12/28/2006 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/5/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/8/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Septic Shock Death 12/21/2006 79 Female 126 lb 1/5/2007 Other Health Professional Germany
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/14/2006 Male 157 lb 1/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Required Intervention 9/1/2006 54 Male 1/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 93 Female 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 12/27/2006 84 Male 1/24/2007 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/26/2007 United Kingdom
Primary
Secondary
Concomitant
Viral Infection Hospitalization 11/19/2006 70 Female 2/7/2007 Physician Sweden
Primary
Concomitant
Vomiting Hospitalization 2/12/2007 74 Male 152 lb 2/15/2007 Physician United States
Primary
Secondary
Concomitant
Cough Disability Female 2/13/2007 United Kingdom
Primary
Concomitant
Hypotension Hospitalization 2/13/2007 84 Male 3/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Wound Other Serious 8/14/2006 Female 137 lb 3/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hypotension Hospitalization 2/13/2007 84 Male 3/19/2007 United Kingdom
Primary
Concomitant
Pain Hospitalization 2/15/2007 85 Female 99 lb 3/23/2007 United Kingdom
Primary
Concomitant
Urine Output Decreased Hospitalization 2/26/2007 85 Male 204 lb 3/29/2007 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/1/2006 75 Male 163 lb 4/27/2007 Netherlands
Primary
Concomitant
Throat Irritation Other Serious 12/19/2006 62 Female 190 lb 3/15/2007 Pharmacist United States
Primary
Concomitant
Vision Blurred Hospitalization 45 Male 201 lb 5/14/2007 Physician United Kingdom
Primary
Concomitant
Pallor Hospitalization 5/11/2006 79 Female 154 lb 5/18/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 9/1/2006 75 Male 163 lb 5/29/2007 Netherlands
Primary
Concomitant
Death Death 12/21/2006 Female 126 lb 6/5/2007 Physician Germany
Primary
Concomitant
Insomnia Other Serious 3/15/2007 6/7/2007 Consumer United Kingdom
Primary
Concomitant
Vomiting Hospitalization 3/1/2007 53 Female 141 lb 6/15/2007 Pharmacist Germany
Primary
Concomitant
Tendonitis Disability 10/1/2006 81 Female 148 lb 6/12/2007 United Kingdom
Primary
Concomitant
Breast Cancer Stage Iii Hospitalization 9/19/2005 Female 212 lb 6/22/2007 Physician United Kingdom
Primary
Concomitant
Tendonitis Disability 10/1/2006 81 Female 148 lb 6/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Supraventricular Tachycardia Other Serious 12/1/2004 Female 7/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Supraventricular Tachycardia Other Serious 12/1/2004 Female 7/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Supraventricular Tachycardia Other Serious 12/1/2004 Female 7/7/2007 United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Male 7/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hepatic Failure Life Threatening 5/30/2007 62 Female 7/17/2007 Other Health Professional France
Primary
Concomitant
Syncope Hospitalization 5/22/2006 Male 201 lb 7/24/2007 Germany
Primary
Concomitant
Troponin Increased Other Serious Male 159 lb 7/24/2007 Physician Australia
Primary
Concomitant
Speech Disorder Hospitalization 3/27/2006 68 Male 150 lb 9/27/2007
Primary
Secondary
Concomitant
Fracture Other Serious 94 Female 9/28/2007 Physician United Kingdom
Primary
Concomitant
Speech Disorder Hospitalization 3/27/2006 68 Male 150 lb 9/28/2007
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 3/27/2006 68 Male 150 lb 10/1/2007
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 6/23/2007 67 Male 223 lb 10/23/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Azotaemia Life Threatening 8/1/2007 Male 10/25/2007 Denmark
Primary
Concomitant
Drug Ineffective Hospitalization 10/14/2007 84 Female 11/20/2007 United Kingdom
Primary
Concomitant
Epistaxis Hospitalization 9/5/2007 Female 11/29/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Hepatic Encephalopathy Life Threatening 11/18/2007 62 Male 12/5/2007 Physician United States
Primary
Concomitant
Rectal Cancer Metastatic Hospitalization 6/1/2007 87 Male 143 lb 11/30/2007 Consumer Germany
Primary
Concomitant
Hepatic Encephalopathy Life Threatening 11/18/2007 62 Male 12/7/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 5/27/2006 89 Male 12/3/2007 Pharmacist United Kingdom
Primary
Concomitant
Hepatic Encephalopathy Life Threatening 11/18/2007 62 Male 12/11/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 5/27/2006 89 Male 12/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/27/2006 89 Male 12/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Peritonitis Bacterial 11/23/2007 75 Male 12/19/2007 Canada
Primary
Concomitant
Vomiting Hospitalization 6/1/2007 87 Male 143 lb 12/14/2007 Consumer Germany
Primary
Concomitant
Overdose Hospitalization 10/14/2007 84 Female 12/14/2007 Pharmacist Denmark
Primary
Concomitant
Peritonitis Bacterial 11/23/2007 75 Male 12/27/2007 Canada
Primary
Concomitant
Overdose Hospitalization 10/14/2007 84 Female 12/20/2007 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 9/1/2006 75 Male 163 lb 1/29/2008 Netherlands
Primary
Concomitant
Pyrexia Hospitalization 7/16/2006 Male 293 lb 2/6/2008 United Kingdom
Primary
Concomitant
Rash Hospitalization 7/17/2006 Male 293 lb 2/26/2008 United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/19/2008 83 Male 2/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 1/1/2007 80 Female 96 lb 3/12/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 5/1/2007 87 Male 143300 lb 3/14/2008 Physician Germany
Primary
Concomitant
Sepsis Death 7/11/2007 Female 154 lb 3/31/2008 United Kingdom
Primary
Concomitant
Sepsis Death 7/11/2007 Female 154 lb 4/8/2008 United Kingdom
Primary
Concomitant
Self-injurious Ideation Other Serious Male 193 lb 4/10/2008 United States
Primary
Concomitant
Malaise Other Serious Male 179 lb 4/11/2008 Physician Germany
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 6/26/2006 59 Female 240 lb 4/15/2008 Physician United States
Primary
Secondary
Concomitant
Spinal Disorder Other Serious Male 179 lb 4/22/2008 Physician Germany
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 6/26/2006 59 Female 240 lb 4/25/2008 Physician United States
Primary
Secondary
Concomitant
Depression Life Threatening 9/5/2005 5/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Hospitalization 10/20/2006 Male 130 lb 5/21/2008 United States
Primary
Concomitant
Syncope Vasovagal Hospitalization 6/26/2006 59 Female 240 lb 5/13/2008 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 3/1/2007 45 Male 5/28/2008 Consumer Canada
Primary
Secondary
Concomitant
Renal Failure Hospitalization 5/1/2007 87 Male 143 lb 6/11/2008 Consumer Germany
Primary
Concomitant
Subarachnoid Haemorrhage Hospitalization 5/25/2008 81 Male 6/26/2008 Consumer Norway
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 3/27/2006 68 Male 150 lb 6/30/2008 Physician United States
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 3/27/2006 Male 7/1/2008 Physician United States
Primary
Secondary
Concomitant
Self-injurious Ideation Other Serious 12/1/2007 Male 193 lb 7/1/2008 United States
Primary
Concomitant
Petit Mal Epilepsy Hospitalization 5/25/2008 81 Male 7/1/2008 Physician Norway
Primary
Secondary
Concomitant
Petit Mal Epilepsy Hospitalization 5/25/2008 81 Male 7/1/2008 Physician Norway
Primary
Secondary
Concomitant
Bone Disorder Required Intervention 3/26/2008 59 Female 4/8/2008 Physician United States
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Hospitalization 5/25/2008 81 Male 7/3/2008 Other Health Professional Norway
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Death 7/1/2008 Male 7/9/2008 Canada
Primary
Concomitant
Vascular Occlusion Hospitalization 6/23/2007 71 Male 7/18/2008 Consumer Germany
Primary
Concomitant
Prostate Cancer Death 7/1/2008 Male 7/25/2008 Canada
Primary
Concomitant
Speech Disorder Hospitalization 3/27/2006 68 Male 150 lb 7/29/2008 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 3/30/2008 80 Male 7/23/2008 New Zealand
Primary
Concomitant
Self-injurious Ideation Other Serious 12/1/2007 Male 193 lb 8/6/2008 United States
Primary
Concomitant
Psychotic Disorder Hospitalization 3/27/2006 68 Male 150 lb 7/31/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Prostate Cancer Hospitalization 76 Male 8/1/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 10/21/2006 85 Female 8/9/2008 United Kingdom
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 6/1/2008 75 Male 161 lb 8/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Psoriasis Other Serious 3/1/2008 81 Female 8/12/2008 United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/23/2007 71 Male 8/25/2008 Physician Germany
Primary
Concomitant
Vomiting Hospitalization 3/30/2008 80 Male 8/14/2008 New Zealand
Primary
Concomitant
Cardiac Failure Other Serious 1/1/2008 Female 183 lb 9/10/2008 Physician Germany
Primary
Concomitant
Arrhythmia Death 6/30/2008 64 Male 9/11/2008 Physician Philippines
Primary
Secondary
Concomitant
Psoriasis Other Serious 3/1/2008 81 Female 9/9/2008 United Kingdom
Primary
Concomitant
Bone Disorder Hospitalization 3/26/2008 59 Female 9/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Confusional State Death 80 Male 123 lb 10/29/2008 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 8/10/2008 71 Male 11/6/2008 Netherlands
Primary
Concomitant
Troponin Increased Life Threatening 6/11/2008 59 Male 174 lb 11/10/2008 Physician Germany
Primary
Secondary
Concomitant

Drug Data