Pioglitazone combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Insomnia 1/1/2006 59 Female 10/11/2006 Consumer United States
Primary
Concomitant
Dysgeusia 8/8/2006 64 Female 196 lb 10/11/2006 Consumer
Primary
Concomitant
Heart Rate Irregular 10/1/2006 60 Female 184 lb 1/12/2007 Consumer United States
Primary
Concomitant
Insomnia 9/28/2006 55 Male 245 lb 1/12/2007 Consumer United States
Primary
Concomitant
Haemorrhagic Stroke Hospitalization 3/27/2007 74 4/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Other Serious 1/1/2000 49 Male 348 lb 4/20/2007 United States
Primary
Concomitant
Wound Necrosis Death 47 Female 5/18/2007 United States
Primary
Concomitant
Urticaria Other Serious 1/1/2007 38 Female 4/13/2007 Pharmacist United States
Primary
Concomitant
Urticaria Other Serious 6/11/2007 Female 270 lb 6/13/2007 Other Health Professional United States
Primary
Concomitant
Epilepsy Other Serious 6/6/2007 56 Female 190 lb 7/31/2007 Physician United Kingdom
Primary
Concomitant
Feeling Abnormal Other Serious 6/23/2007 77 Female 182 lb 8/2/2007 Consumer United Kingdom
Primary
Concomitant
Vomiting Other Serious 7/3/2007 67 Female 377 lb 10/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Feeling Abnormal Other Serious 6/23/2007 77 Female 187 lb 10/19/2007 Physician United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 59 Male 11/1/2007 United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 3/1/2007 59 Male 11/2/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 7/19/2007 Male 11/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Drug Ineffective 7/1/2007 Female 435 lb 11/29/2007 Consumer United States
Primary
Concomitant
Throat Cancer Other Serious 10/26/2007 60 Male 289 lb 12/4/2007 United Kingdom
Primary
Concomitant
Joint Swelling Other Serious 1/1/2007 46 Male 12/14/2007 Pharmacist Germany
Primary
Concomitant
Interacting
Herpes Zoster 9/21/2007 Female 158 lb 12/14/2007 United States
Primary
Concomitant
Myositis Life Threatening 11/14/2007 46 Male 12/28/2007
Primary
Secondary
Concomitant
Throat Cancer Other Serious 10/26/2007 60 Male 289 lb 1/18/2008 United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 1/23/2008 47 Female 256 lb 2/19/2008 Physician United Kingdom
Primary
Concomitant
Throat Cancer Other Serious 10/26/2007 60 Male 289 lb 2/19/2008 Physician United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/23/2008 47 Female 256 lb 2/22/2008 Physician United Kingdom
Primary
Concomitant
Respiratory Arrest Hospitalization 2/15/2008 66 Male 3/4/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Arrest Hospitalization 2/15/2008 66 Male 3/12/2008 Physician United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 2/1/2006 47 Female 4/8/2008 Pharmacist United States
Primary
Secondary
Concomitant
Hot Flush 6/5/2008 Male 8/27/2008 United States
Primary
Concomitant
Flushing 6/1/2008 Female 8/27/2008 United States
Primary
Concomitant
Muscular Weakness 7/16/2008 Male 250 lb 8/29/2008 United States
Primary
Concomitant
Tremor Hospitalization 8/14/2008 80 Male 160 lb 8/29/2008 Pharmacist United States
Primary
Secondary
Injection Site Pain 1/23/2007 Female 280 lb 9/13/2008 United States
Primary
Concomitant
Blood Potassium Increased Hospitalization 9/4/2008 Female 9/17/2008 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 8/4/2008 80 Female 110 lb 10/6/2008 Pharmacist United States
Primary
Concomitant
Swollen Tongue Life Threatening 9/30/2008 72 Male 10/16/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Blood Potassium Increased Required Intervention 9/4/2008 60 Female 10/8/2008 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 7/29/2008 Female 11/26/2008 United States
Primary
Concomitant
Muscular Weakness 7/16/2008 Male 250 lb 11/26/2008 United States
Primary
Concomitant
Treatment Noncompliance Life Threatening 10/14/2008 43 Female 12/3/2008 Other Health Professional United States
Primary
Concomitant
Injection Site Pain 10/1/2008 Male 321 lb 12/12/2008 Physician United States
Primary
Concomitant
Completed Suicide Death 1/1/2007 50 Male 12/19/2008 Physician United States
Primary
Secondary
Completed Suicide Death 50 Male 12/29/2008 Pharmacist United States
Primary
Secondary
Rhabdomyolysis Hospitalization 10/11/2008 86 Female 148 lb 1/13/2009 Pharmacist United States
Primary
Concomitant
Completed Suicide Death 1/23/2009 Other Health Professional United States
Primary
Secondary
Poisoning Deliberate Death 50 Male 1/19/2009 Physician United States
Primary
Secondary
Death Death 1/1/2007 50 Male 2/3/2009 Pharmacist United States
Primary
Secondary
Weight Decreased Other Serious 1/1/2005 Female 283 lb 2/17/2009 Consumer United States
Primary
Concomitant
Histoplasmosis Other Serious 75 Female 3/13/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious Male 256 lb 3/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Myalgia Other Serious 1/1/2006 56 Male 4/6/2009 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 4/1/2005 69 Male 12/4/2008 United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 4/16/2009 62 Male 4/24/2009 Physician South Africa
Primary
Concomitant
Pancreatitis Other Serious 55 Male 304 lb 6/2/2009 Physician United Kingdom
Primary
Concomitant
Pancreatitis Other Serious 4/16/2009 Male 6/10/2009 Physician South Africa
Primary
Concomitant
Swollen Tongue Other Serious 3/25/2009 54 Female 260 lb 6/16/2009 Physician United Kingdom
Primary
Concomitant
Muscle Disorder Other Serious 67 Male 6/25/2009 Other Health Professional France
Primary
Secondary
Concomitant
Androgenetic Alopecia Disability 1/1/2008 55 8/5/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Androgenetic Alopecia Disability 1/1/2008 50 Female 180 lb 8/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Life Threatening 7/11/2009 39 Male 260 lb 8/7/2009 Physician United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 6/1/2009 79 Male 8/7/2009 Physician Germany
Primary
Secondary
Concomitant
Pancreatitis Acute Life Threatening Male 266 lb Physician United States
Primary
Secondary
Concomitant
Pruritus 9/16/2008 Female 8/22/2009 United States
Primary
Concomitant
Androgenetic Alopecia Disability 1/1/2008 50 Female 180 lb 8/25/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Left Ventricular Failure Other Serious 4/9/2009 76 Male 8/20/2009 United Kingdom
Primary
Concomitant
Androgenetic Alopecia Disability 1/1/2008 50 Female 8/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Emotional Distress Disability 1/1/2008 50 Female 180 lb 8/26/2009
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process 10/1/2008 Male 321 lb 9/12/2009 Physician United States
Primary
Concomitant
Urine Odour Abnormal Other Serious Male 9/29/2009 Canada
Primary
Concomitant
Renal Impairment Other Serious 5/21/2009 59 Female 183 lb 10/27/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 9/1/2009 69 Male 168 lb 9/8/2009 Pharmacist United States
Primary
Concomitant
Myositis Life Threatening 11/14/2007 4 Male 10/23/2009 United Kingdom
Primary
Concomitant
Muscle Spasms 9/1/2008 66 Male 11/13/2009 Consumer United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 3/1/2007 59 Male 11/17/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 3/1/2007 59 Male 11/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Androgenetic Alopecia Disability 1/1/2008 Male 180 lb 11/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Androgenetic Alopecia Disability 1/1/2008 55 Female 180 lb 11/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 3/1/2007 59 Male 11/24/2009
Primary
Secondary
Concomitant
Androgenetic Alopecia Disability 1/1/2008 55 Female 180 lb 12/9/2009 United Kingdom
Primary
Secondary
Concomitant
Androgenetic Alopecia Disability 1/1/2008 50 Female 180 lb 12/4/2009 Consumer
Primary
Secondary
Concomitant
Uveitis Other Serious 11/1/2008 Male 175 lb 12/15/2009 Consumer United States
Primary
Concomitant
Urticaria Other Serious 8/4/2009 50 Female 243 lb 12/28/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urticaria Other Serious 8/4/2009 50 Female 243 lb 12/31/2009 United Kingdom
Primary
Concomitant
Urticaria Other Serious 8/4/2009 50 Female 12/30/2009 United Kingdom
Primary
Concomitant
Androgenetic Alopecia Disability 1/1/2008 Male 180 lb 1/11/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Toxicity Death 34 Male 1/11/2010 Other Health Professional United States
Primary
Secondary
Androgenetic Alopecia Disability 1/1/2008 55 Female 180 lb 1/11/2010 United Kingdom
Primary
Secondary
Concomitant
Uveitis Other Serious 2/5/2008 Male 175 lb 1/11/2010 Consumer United States
Primary
Concomitant
Pancytopenia Other Serious 12/7/2009 82 Male 187 lb 1/15/2010 Physician United States
Primary
Secondary
Concomitant
Androgenetic Alopecia Disability 1/1/2008 Female 180 lb 1/21/2010 United Kingdom
Primary
Secondary
Concomitant
Drug Toxicity Death 33 Female 1/26/2010 United States
Primary
Secondary
Renal Impairment Other Serious 12/24/2007 60 Male 1/27/2010 Lawyer United States
Primary
Concomitant
Somnolence Other Serious 11/25/2009 82 Male 187 lb 1/26/2010 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 10/29/2007 60 Male 2/2/2010 Lawyer United States
Primary
Concomitant
Poisoning Death 1/1/2008 33 Female 2/1/2010 Physician United States
Primary
Secondary
High Density Lipoprotein Decreased Other Serious 3/13/2002 71 Male 2/11/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Poisoning Death 1/1/2008 34 Male 2/2/2010 Physician United States
Primary
Secondary
Poisoning Death 1/1/2008 34 Male 2/1/2010 Physician United States
Primary
Secondary
Acute Myocardial Infarction Death 10/30/2009 Male 2/15/2010 Physician United Kingdom
Primary
Concomitant
Treatment Noncompliance Other Serious 8/12/2009 Female 129 lb Pharmacist United States
Primary
Concomitant
Completed Suicide Death 33 Female 2/26/2010 Other Health Professional United States
Primary
Secondary
Somnolence Other Serious 11/25/2009 82 Male 187 lb 2/19/2010 Physician United States
Primary
Secondary
Concomitant
Completed Suicide Death 3/4/2010 Physician United States
Primary
Secondary
Intentional Drug Misuse Death 3/5/2010 Physician United States
Primary
Secondary
Blood Glucose Increased Other Serious 1/1/2010 Male 214 lb 3/11/2010 Consumer United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/30/2010 70 Male 3/12/2010 Physician Germany
Primary
Concomitant
Death Death 1/1/2008 34 Male 3/25/2010 Other Health Professional United States
Primary
Secondary
Death Death 1/1/2008 33 Female 3/25/2010 Other Health Professional United States
Primary
Secondary
Weight Decreased Other Serious 1/1/2008 Male 175 lb 3/29/2010 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 10/22/2007 63 Female 4/7/2010 Other Health Professional United States
Primary
Concomitant
Poisoning Death 1/1/2008 34 Male 4/6/2010 Physician United States
Primary
Secondary
Spinal Cord Injury Cervical Life Threatening 10/30/2009 66 Male 229 lb 4/13/2010 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 11/25/2009 82 Male 187 lb 4/8/2010 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 12/1/2007 60 Male 4/21/2010 United States
Primary
Concomitant
Myalgia Other Serious 72 Female 213 lb 4/21/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Spinal Cord Injury Cervical Life Threatening 10/30/2009 66 Male 229 lb 4/22/2010 Physician United States
Primary
Secondary
Concomitant
Myalgia Other Serious 6/1/2006 72 Female 214 lb 4/22/2010 Germany
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 10/29/2007 60 Male 4/26/2010 Lawyer United States
Primary
Concomitant
Myalgia Other Serious 72 Female 213 lb 4/23/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Dizziness Other Serious 3/25/2010 62 Male 227 lb 4/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Myalgia Other Serious 72 Female 213 lb 5/4/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 2/23/2008 60 Female 150 lb 5/5/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Myalgia Other Serious 6/1/2006 72 Female 213 lb 5/5/2010 United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 11/25/2009 82 Male 187 lb 5/5/2010 Physician United States
Primary
Secondary
Concomitant
Myalgia Other Serious 72 Female 212 lb 5/4/2010 United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 11/25/2009 82 Male 187 lb 5/13/2010 Physician United States
Primary
Secondary
Concomitant
Somnolence Other Serious 11/25/2009 82 Male 187 lb 5/18/2010 Physician United States
Primary
Secondary
Concomitant
Myalgia Other Serious 6/1/2006 72 Female 214 lb 5/27/2010 Germany
Primary
Secondary
Concomitant
Myalgia Other Serious 72 Female 213 lb 5/27/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 11/25/2009 82 Male 187 lb 5/25/2010 Physician United States
Primary
Secondary
Concomitant
Myalgia Other Serious 6/1/2006 72 Female 214 lb 6/11/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Myalgia Other Serious 72 Female 212 lb 6/5/2010 United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Other Serious 10/1/2008 60 Male 205 lb 6/15/2010 Lawyer United States
Primary
Secondary
Concomitant
Uveitis Disability 4/2/2010 69 Male 174 lb 6/16/2010 Physician United Kingdom
Primary
Concomitant
Myalgia Other Serious 72 Female 213 lb 6/17/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Swelling Face Life Threatening 6/21/2010 64 Male 7/16/2010 Consumer United States
Primary
Secondary
Concomitant
Sedation Hospitalization 4/26/2010 84 Male 211 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Swelling Face Life Threatening 6/21/2010 64 Male 8/10/2010 Consumer United States
Primary
Secondary
Concomitant
Swelling Face Life Threatening 6/21/2010 64 Male 8/16/2010 Consumer United States
Primary
Secondary
Concomitant
Myalgia Other Serious 6/1/2006 72 Female 214 lb 8/17/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Spinal Cord Injury Cervical Life Threatening 10/30/2009 66 Male 229 lb 8/27/2010 Physician United States
Primary
Secondary
Concomitant
Intestinal Dilatation Hospitalization 7/21/2010 72 Male 8/30/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Intestinal Dilatation Hospitalization 7/21/2010 72 Male 9/2/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 6/14/2010 54 Male 230 lb 8/31/2010 Physician United Kingdom
Primary
Concomitant
Intestinal Dilatation Hospitalization 7/21/2010 72 Male 9/10/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Intestinal Dilatation Hospitalization 7/21/2010 72 Male 9/21/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pancreatic Carcinoma Other Serious 10/1/2009 43 Male 185 lb 9/20/2010 Other Health Professional United Kingdom
Primary
Concomitant
Left Ventricular Dysfunction Other Serious 7/20/2010 60 Female 9/27/2010 Pharmacist United Kingdom
Primary
Concomitant
Weight Increased Other Serious 74 Male 10/7/2010 Other Health Professional Brazil
Primary
Secondary
Rash Pruritic Other Serious 9/8/2010 82 Male 430 lb 10/21/2010 United States
Primary
Concomitant

Drug Data