Alfacalcidol combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Somnolence Hospitalization 6/28/2005 62 Male 141 lb 1/24/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Acute Myocardial Infarction Death 2/25/2006 62 Male 256 lb 3/30/2006 Physician Australia
Primary
Concomitant
Pulmonary Embolism Life Threatening 2/21/2006 74 Female 168 lb 4/12/2006 Physician Israel
Primary
Concomitant
Palpitations Hospitalization 6/1/2006 56 Female 115 lb 6/16/2006 Physician Japan
Primary
Concomitant
Therapy Cessation Other Serious 5/20/2006 67 Female 163 lb 8/7/2006 Physician Austria
Primary
Concomitant
Vomiting Hospitalization 7/25/2002 80 Male 10/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Troponin Increased Other Serious 91 Male 10/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vocal Cord Thickening Hospitalization 8/28/2003 Male 172 lb 3/23/2007 Physician United Kingdom
Primary
Concomitant
Swollen Tongue Other Serious 2/27/2007 82 Male 186 lb 4/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Peritonitis 3/15/2007 41 Female 4/25/2007 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 3/1/2007 53 Female 141 lb 6/15/2007 Pharmacist Germany
Primary
Concomitant
Reticulocyte Count Decreased Other Serious 5/3/2007 Male 190 lb 10/11/2007 Physician Germany
Primary
Concomitant
Polyomavirus-associated Nephropathy Hospitalization 5/15/2007 Male 192 lb 10/18/2007 Consumer Sweden
Primary
Concomitant
Sleep Disorder Hospitalization 6/1/2005 62 Male 10/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sleep Disorder Hospitalization 6/1/2005 62 Male 10/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Reticulocyte Count Decreased Other Serious 5/3/2007 Male 190 lb 10/29/2007 Physician Germany
Primary
Concomitant
Sleep Disorder Hospitalization 6/1/2005 62 Male 11/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Reticulocyte Count Decreased Other Serious 5/3/2007 Male 190 lb 11/19/2007 Physician Germany
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 73 Male 12/7/2007 United Kingdom
Primary
Concomitant
Polyomavirus-associated Nephropathy Hospitalization 5/15/2007 Male 192 lb 12/21/2007 Consumer Sweden
Primary
Secondary
Concomitant
Polyomavirus-associated Nephropathy Hospitalization 3/22/2007 Male 192 lb 1/3/2008 Consumer Sweden
Primary
Secondary
Concomitant
Fungal Peritonitis Hospitalization 3/3/2008 61 Female 4/21/2008 Other Health Professional
Primary
Secondary
Concomitant
Drug Interaction Life Threatening 2/7/2007 54 Male 4/25/2008 Other Health Professional Netherlands
Primary
Concomitant
Interacting
Loss Of Consciousness Life Threatening 4/16/2008 87 Female 5/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Peritonitis Bacterial Other Serious 5/2/2008 29 Female 143 lb 6/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neurotoxicity Other Serious 6/11/2008 6/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Neurotoxicity Other Serious 6/11/2008 72 Male 7/10/2008 Consumer United Kingdom
Primary
Concomitant
Respiratory Tract Infection Other Serious 4/11/2004 Female 7/15/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Hot Flush Other Serious 5/24/2008 Male 181 lb 8/14/2008 Physician Germany
Primary
Concomitant
Blood Parathyroid Hormone Increased Other Serious 9/5/2006 Female 159 lb 9/25/2008 Germany
Primary
Concomitant
Blood Parathyroid Hormone Increased Other Serious 9/5/2006 Female 159 lb 10/1/2008 Germany
Primary
Concomitant
Hot Flush Other Serious 5/24/2008 Male 181 lb 11/24/2008 Physician Germany
Primary
Concomitant
Vertigo Other Serious 1/1/2005 Female 128 lb 11/25/2008 Physician Germany
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 5/15/2008 63 Male 172 lb 2/11/2009 Physician Germany
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 67 Male 3/5/2009 United Kingdom
Primary
Concomitant
Paralysis Other Serious 58 Male 4/14/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Paralysis Other Serious 12/1/2008 58 Male 4/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 44 Female 5/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Arrhythmia Life Threatening 44 Female 6/5/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 5/10/2009 78 6/10/2009 Pharmacist Canada
Primary
Secondary
Concomitant
Hypokalaemia Life Threatening 44 Female 6/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 44 Female 6/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 44 Female 6/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 6/3/2009 Female 7/8/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Life Threatening 6/8/2009 Female 7/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 12/1/2008 Male 8/6/2009 Physician United Kingdom
Primary
Concomitant
Hallucination, Visual Other Serious 8/1/2009 77 Male 189 lb 9/8/2009 Physician United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 12/1/2008 73 Female 106 lb 9/14/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vertigo Hospitalization 8/31/2009 Female 151 lb 10/27/2009 Physician Germany
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 6/1/2008 75 Male 10/23/2009 United Kingdom
Primary
Concomitant
Paralysis Other Serious 58 Male 11/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vertigo Hospitalization 8/31/2009 Female 151 lb 11/18/2009 Physician Germany
Primary
Concomitant
Respiratory Distress Life Threatening 2/1/2009 Female 196 lb 11/23/2009 Physician United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 72 Male 12/14/2009 Consumer United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 4/23/2009 Female 12/15/2009 Physician Denmark
Primary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 4/23/2009 Female 12/15/2009 Denmark
Primary
Concomitant
Vertigo Hospitalization 8/31/2009 Female 151 lb 12/22/2009 Physician Germany
Primary
Concomitant
Hypokalaemia Life Threatening 44 Female 1/19/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Aortic Stenosis Death 11/13/2009 1/19/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 4/23/2009 Female 2/1/2010 Physician Denmark
Primary
Concomitant
Interacting
Hypokalaemia Life Threatening 44 Female 2/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vertigo Hospitalization 8/31/2009 Female 146 lb 3/31/2010 Physician Germany
Primary
Concomitant
Rhabdomyolysis Life Threatening 46 Female 6/24/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 5/26/2010 79 Male 6/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 5/26/2010 79 Male 7/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 46 Female 7/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 46 Female 7/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 46 Female 7/9/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 46 Female 7/2/2010 Other Health Professional
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 46 Female 6/18/2010 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 46 Female 6/30/2010 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 46 Female 7/6/2010 United Kingdom
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 65 Male 7/21/2010 Pharmacist Canada
Primary
Concomitant
Interacting
Pneumonitis Other Serious 8/1/2009 61 Male 217 lb 7/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Disorder Other Serious 8/1/2009 61 Male 217 lb 7/26/2010 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 46 Female 8/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 59 Male 8/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 59 Male 8/30/2010
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 59 Male 9/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 46 Female 9/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 9/29/2010 59 Female 110 lb 10/8/2010 Consumer Singapore
Primary
Secondary
Concomitant
Death Death 10/17/2010 55 Male 143 lb 10/25/2010 Physician Greece
Primary
Concomitant
Vomiting Life Threatening 9/29/2010 59 Female 110 lb 10/27/2010 Consumer Singapore
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 65 Male 10/28/2010 Other Health Professional France
Primary
Concomitant
Interacting
Viith Nerve Paralysis Hospitalization 10/23/2010 12/8/2010 Physician Japan
Primary
Concomitant
Viith Nerve Paralysis Hospitalization 10/23/2010 12/13/2010 Physician Japan
Primary
Concomitant
Chorioretinopathy Other Serious 1/1/2010 50 Male 12/22/2010 Physician United Kingdom
Primary
Concomitant
Vision Blurred Hospitalization 10/23/2010 12/23/2010 Physician Japan
Primary
Concomitant
Vision Blurred Hospitalization 10/23/2010 63 Female 108 lb 2/7/2011 Other Health Professional Japan
Primary
Concomitant
Sudden Death Death 61 Female 319 lb 2/15/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatitis Acute Hospitalization 2/24/2011 73 Female 146 lb 3/4/2011 Physician Greece
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 2/24/2011 73 Female 146 lb 3/8/2011 Physician Greece
Primary
Secondary
Concomitant
Toxicity To Various Agents Hospitalization 2/20/2011 3/10/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxicity To Various Agents Hospitalization 2/20/2011 67 Female 116 lb 3/11/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 2/20/2011 67 Female 116 lb 3/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 2/24/2011 73 Female 146 lb 3/29/2011 Physician Greece
Primary
Secondary
Concomitant
Nausea Hospitalization 2/20/2011 3/30/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/20/2011 67 Female 116 lb 3/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 12/27/2010 75 Male 196 lb 4/20/2011 Physician United Kingdom
Primary
Concomitant
Bronchopneumonia Death 69 Male 172 lb 4/25/2011 Other Health Professional Germany
Primary
Concomitant
Pancreatitis Acute Hospitalization 2/24/2011 73 Female 146 lb 4/28/2011 Physician Greece
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 4/22/2011 5/3/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 12/27/2010 75 Male 196 lb 5/3/2011 Physician United Kingdom
Primary
Concomitant
Circulatory Collapse Other Serious 3/30/2011 81 Male 256 lb 5/5/2011 Other Health Professional Netherlands
Primary
Concomitant
Renal Failure Disability 70 Male 174 lb 5/25/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Disability 70 Male 5/26/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Disability 70 Male 174 lb 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Disability 70 Male 174 lb 6/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 1/1/2011 25 Female 97 lb 6/2/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 4/22/2011 6/10/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemodialysis Disability 70 Male 174 lb 6/2/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 6/23/2011 77 Female 176 lb 7/20/2011 Physician Greece
Primary
Concomitant
Disease Progression Other Serious 7/28/2011 Male 148 lb 9/2/2011 Physician United Kingdom
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 7/28/2011 Male 148 lb 10/6/2011 Other Health Professional United Kingdom
Primary
Concomitant
Agranulocytosis Hospitalization 9/26/2011 77 Female 282 lb 11/2/2011 Physician Netherlands
Primary
Secondary
Concomitant
Agranulocytosis Hospitalization 9/26/2011 77 Female 282 lb 11/17/2011 Physician Netherlands
Primary
Secondary
Concomitant
Lobar Pneumonia Hospitalization 3/10/2011 81 Female 123 lb 11/24/2011 Other Health Professional United Kingdom
Primary
Concomitant
Fall Hospitalization 12/27/2010 75 Male 196 lb 11/30/2011 United Kingdom
Primary
Concomitant
Cardiac Arrest Hospitalization 12/27/2010 75 Male 196 lb 12/15/2011 Physician United Kingdom
Primary
Concomitant
Hypoglycaemia Hospitalization 12/27/2010 75 Male 196 lb 1/20/2012 Physician United Kingdom
Primary
Concomitant
Hypocalcaemia Other Serious 2/2/2012 79 Female 2/20/2012 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 1/17/2012 75 Male 134 lb 3/19/2012 Physician Germany
Primary
Concomitant
Abdominal Discomfort Death Male 3/23/2012 Physician United Kingdom
Primary
Concomitant
Eye Haemorrhage Other Serious 3/9/2012 46 Male 5/10/2012 Physician United Kingdom
Primary
Concomitant
Personality Change Other Serious 1/16/2012 69 Female 154 lb 5/15/2012 Consumer Canada
Primary
Concomitant
Acute Myocardial Infarction Death 5/6/2012 64 Male 5/18/2012 Other Health Professional Portugal
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 5/17/2012 83 Female 6/11/2012 Other Health Professional United Kingdom
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 5/17/2012 83 Female 6/12/2012 Other Health Professional United Kingdom
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 5/17/2012 83 Female 6/15/2012 Other Health Professional Israel
Primary
Concomitant
Noninfectious Peritonitis Other Serious 4/8/2012 78 Male 6/18/2012 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/7/2012 56 Male 110 lb 7/3/2012 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Hernia Hospitalization 6/20/2012 66 Female 7/19/2012 Consumer United Kingdom
Primary
Concomitant
Urosepsis Hospitalization 4/8/2012 78 Male 7/27/2012 Physician Netherlands
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 5/17/2012 83 Female 10/1/2012 Other Health Professional Il
Primary
Concomitant
Systemic Inflammatory Response Syndrome Death 2/15/2012 69 Male 211 lb 10/3/2012 Physician De
Primary
Concomitant
Cerebrovascular Accident Disability 11/9/2010 75 Male 196 lb 9/4/2012 Physician Gb
Primary
Secondary
Concomitant
Pain Other Serious 8/10/2012 56 Male 185 lb 9/28/2012 Consumer Country Not Specified
Primary
Concomitant
Sudden Death Death 61 Female 319 lb 9/18/2012 Other Health Professional Gb
Primary
Concomitant
Meningitis Hospitalization 6/2012 79 Female 9/25/2012 Physician Gb
Primary
Concomitant
Rhabdomyolysis Other Serious 8/28/2012 89 Male 9/26/2012 Other Health Professional Gb
Primary
Concomitant
Interacting
Rash Erythematous Other Serious 9/1/2012 57 Female 9/27/2012 Us
Primary
Concomitant
Rhabdomyolysis Disability 8/28/2012 89 Male 10/1/2012 Pharmacist Gb
Primary
Concomitant
Interacting
Rhabdomyolysis Disability 8/28/2012 89 Male 10/2/2012 Pharmacist Gb
Primary
Secondary
Concomitant
Rhabdomyolysis Disability 8/28/2012 89 Male 10/3/2012 Pharmacist Gb
Primary
Concomitant
Interacting
Urinary Tract Infection Other Serious Male 154 lb 12/6/2012 Other Health Professional Country Not Specified
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 2012 Male 1/15/2013 Physician Country Not Specified
Primary
Concomitant
Renal Failure Acute Disability 1/1/2009 64 Female 252 lb 3/11/2013 Physician Gb
Primary
Concomitant
Renal Failure Acute Disability 1/1/2009 64 Female 252 lb 3/14/2013 Physician Gb
Primary
Concomitant
Renal Cyst Death 9/19/2012 75 Male 200 lb 3/20/2013 Consumer Gb
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious Female 4/16/2013 Physician Gb
Primary
Concomitant

Drug Data