Paclitaxel combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Spleen Disorder Hospitalization 12/21/2005 77 Male 2/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 3/27/2006 72 Male 75 lb 4/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Hospitalization 3/27/2006 72 Male 75 lb 4/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Disorder Hospitalization 3/27/2006 72 Male 75 lb 4/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Disorder Hospitalization 3/27/2006 72 Male 75 lb 5/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence 1/1/2006 70 Female 158 lb 4/3/2006 Consumer United States
Primary
Concomitant
Headache Hospitalization 6/19/2006 63 Female 159 lb 6/29/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatic Lesion Hospitalization 5/25/2006 64 Female 6/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 6/27/2006 56 Female 196 lb 7/14/2006 Physician Italy
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 6/27/2006 56 Female 196 lb 8/11/2006 Physician Italy
Primary
Secondary
Concomitant
Rash Other Serious 7/4/2006 68 Female 126 lb 9/7/2006 Pharmacist Netherlands
Primary
Concomitant
Febrile Neutropenia Hospitalization 9/9/2006 74 Female 137 lb 9/21/2006 Other Health Professional Belgium
Primary
Secondary
Concomitant
Productive Cough Hospitalization 9/1/2006 64 Male 11/14/2006 New Zealand
Primary
Secondary
Concomitant
Skin Disorder Hospitalization 3/27/2006 72 Male 75 lb 12/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 9/1/2006 64 Male 12/20/2006 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Regurgitation Hospitalization 4/15/2007 82 Female 144 lb 4/18/2007 United States
Primary
Secondary
Concomitant
Regurgitation Hospitalization 4/15/2007 82 Female 5/9/2007 Physician United States
Primary
Secondary
Concomitant
Vitamin K Deficiency Hospitalization 4/12/2007 68 Male 4/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Regurgitation Hospitalization 4/15/2007 82 Female 5/18/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/25/2007 66 Male 9/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/25/2007 66 Male 9/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/25/2007 66 Male 10/1/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/25/2007 66 Male 10/16/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Anaemia Hospitalization 11/2/2007 Female 157 lb 11/15/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/25/2007 66 Male 141 lb 12/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 10/15/2007 Female 132 lb 2/7/2008 Physician United Kingdom
Primary
Concomitant
Febrile Neutropenia Hospitalization 4/18/2007 70 Female 110 lb 3/4/2008 Physician Brazil
Primary
Secondary
Concomitant
Oral Intake Reduced Male 324 lb 3/5/2008 Physician United States
Primary
Secondary
Concomitant
Anaemia Hospitalization 11/2/2007 Female 157 lb 4/9/2008 Physician United States
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 4/10/2008 69 Female 207 lb 4/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
General Physical Health Deterioration Hospitalization 10/15/2007 Female 132 lb 4/29/2008 Physician United Kingdom
Primary
Concomitant
Disease Progression Death 69 Female 208 lb 5/2/2008 Consumer United Kingdom
Primary
Concomitant
Cardio-respiratory Arrest Death 69 Female 4/30/2008 United Kingdom
Primary
Concomitant
Cardio-respiratory Arrest Death 4/10/2008 69 Female 208 lb 4/29/2008 United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/9/2008 Male 199 lb 7/24/2008 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 7/9/2008 Male 199 lb 8/1/2008 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 6/20/2008 Female 9/5/2008 Other Health Professional France
Primary
Concomitant
Interacting
International Normalised Ratio Increased Other Serious 6/20/2008 Female 9/8/2008 Other Health Professional France
Primary
Concomitant
Interacting
Vomiting Hospitalization 12/30/2008 Female 108 lb 1/29/2009 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 8/3/2008 63 Male 4/6/2009 Spain
Primary
Secondary
Concomitant
Dizziness Other Serious 4/11/2009 Female 4/29/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Dizziness Other Serious 4/11/2009 Female 5/28/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/30/2008 Female 108 lb 7/2/2009 Physician United States
Primary
Secondary
Concomitant
Fatigue Life Threatening 10/23/2008 60 Female 220 lb 7/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 5/28/2009 Female 8/7/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 5/28/2009 Female 8/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 8/27/2009 Male 166 lb 9/10/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 8/27/2009 Male 166 lb 9/15/2009 Physician United States
Primary
Secondary
Concomitant
Anaemia Hospitalization 9/25/2009 Female 176 lb 10/1/2009 Physician Germany
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 8/27/2009 Male 166 lb 10/5/2009 Physician United States
Primary
Secondary
Concomitant
Anaemia Hospitalization 9/23/2009 Female 176 lb 10/15/2009 Physician Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Required Intervention 3/26/2009 64 Male 192 lb 4/8/2009 Pharmacist United States
Primary
Secondary
Anaemia Hospitalization 10/1/2009 Female 121 lb 11/17/2009 Physician Germany
Primary
Secondary
Concomitant
Spleen Disorder Hospitalization 12/21/2005 77 Male 11/10/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Distress 10/29/2009 72 Male 11/27/2009 Pharmacist United States
Primary
Concomitant
Headache Hospitalization 12/1/2009 Female 12/28/2009 Physician Netherlands
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2009 Female 161 lb 1/12/2010 Physician Austria
Primary
Concomitant
Deep Vein Thrombosis Other Serious 12/30/2009 Male 1/14/2010 Physician United States
Primary
Secondary
Concomitant
Infarction Life Threatening 1/9/2010 Male 95 lb 1/15/2010 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/25/2009 69 Female 2/19/2010 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/25/2009 69 Female 3/5/2010 Physician Germany
Primary
Secondary
Concomitant
Infarction Life Threatening 1/9/2010 Male 95 lb 3/8/2010 Consumer United States
Primary
Secondary
Concomitant
Emphysema Hospitalization 2/18/2010 Male 165 lb 3/11/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/25/2009 69 Female 3/18/2010 Physician Germany
Primary
Secondary
Concomitant
Tooth Loss Other Serious 1/1/2001 62 Male 4/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Confusional State Life Threatening 3/1/2010 67 Female 267 lb 4/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Confusional State Life Threatening 3/1/2010 67 Female 267 lb 4/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 2/18/2010 66 Male 165 lb 4/23/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/21/2010 72 Male 5/25/2010 Other Health Professional United States
Primary
Secondary
Pancreatitis Hospitalization 4/27/2010 48 Male 5/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 5/17/2010 72 Male 6/4/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious Male 6/9/2010 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 72 Male 6/10/2010 Other Health Professional United States
Primary
Secondary
Sepsis Hospitalization 6/7/2010 86 Male 6/21/2010 Physician United States
Primary
Secondary
Concomitant
Pneumothorax Other Serious 4/28/2010 64 Male 112 lb 7/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3/25/2010 54 Male 192 lb 7/13/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/8/2010 74 Female 152 lb 7/14/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumothorax Other Serious 4/28/2010 64 Male 112 lb 7/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/21/2010 69 Female 139 lb 7/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/28/2010 77 Male 7/22/2010 Physician United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 7/10/2010 79 Male 7/23/2010 Physician United States
Primary
Secondary
Concomitant
Klebsiella Test Positive Hospitalization 7/7/2010 82 Female 7/31/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/28/2010 64 Male 112 lb 8/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 7/8/2010 74 Female 152 lb 8/9/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/9/2010 69 Female 139 lb 8/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/9/2010 69 Female 139 lb 8/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Haemarthrosis Hospitalization 7/22/2010 79 Male 8/19/2010 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 8/2/2010 77 Male 8/24/2010 Physician United States
Primary
Secondary
Concomitant
Pneumothorax Other Serious 4/28/2010 64 Male 112 lb 8/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Hospitalization 7/1/2010 73 Female 9/1/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3/25/2010 54 Male 192 lb 9/8/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3/25/2010 54 Male 192 lb 9/13/2010 Physician United States
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Life Threatening 6/24/2008 75 Female 9/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 5/15/2010 59 Male 209 lb 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Confusional State Life Threatening 3/1/2010 67 Female 267 lb 10/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 9/20/2010 65 Male 375 lb 10/12/2010 Physician United States
Primary
Secondary
Concomitant
Faecaloma Hospitalization 7/29/2010 71 Female 10/21/2010 Physician Germany
Primary
Secondary
Concomitant
Panic Attack Hospitalization 8/15/2010 57 Female 121 lb 10/25/2010 Other Health Professional United States
Primary
Concomitant
Oesophagitis Hospitalization 9/20/2010 65 Male 375 lb 10/25/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 8/23/2010 49 Male 154 lb 10/27/2010 Physician United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 5/10/2010 81 Female 10/28/2010 Physician United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 9/20/2010 65 Male 375 lb 11/4/2010 Physician United States
Primary
Secondary
Concomitant
Vena Cava Thrombosis Other Serious 9/21/2010 36 Female 183 lb 11/10/2010 Physician United States
Primary
Secondary
Concomitant
Subileus Hospitalization 7/29/2010 71 Female 11/23/2010 Physician Germany
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 4/5/2009 84 Male 207 lb 11/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 3/25/2010 11/29/2010 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 9/23/2010 73 Male 214 lb 12/1/2010 Physician United States
Primary
Secondary
Concomitant
Faecaloma Hospitalization 4/5/2009 84 Male 207 lb 12/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tumour Compression Hospitalization 9/20/2010 65 Male 170 lb 12/3/2010 Physician United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 11/21/2010 56 Male 12/9/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/19/2010 53 Female 137 lb 12/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 12/1/2010 57 Male 210 lb 12/27/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 9/21/2010 36 Female 183 lb 1/11/2011 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/19/2010 53 Female 138 lb 1/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Faecaloma Hospitalization 4/5/2009 84 Male 207 lb 1/30/2011 Consumer United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 4/27/2010 48 Male 2/10/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Hospitalization 1/17/2011 75 Male 2/17/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cystitis Other Serious 6/9/2010 69 Female 139 lb 3/9/2011 Consumer United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 4/27/2010 48 Male 3/24/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/19/2010 53 Female 138 lb 4/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Fall Hospitalization 1/7/2011 70 Male 3/30/2011 Other Health Professional Denmark
Primary
Concomitant
Alanine Aminotransferase Increased Hospitalization 3/24/2010 70 Female 3/31/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 1/14/2011 Female 3/31/2011 Other Health Professional Denmark
Primary
Concomitant
Haemoglobin Decreased Hospitalization 4/4/2011 66 Female 146 lb 4/7/2011 United States
Primary
Secondary
Concomitant
Syncope Hospitalization 5/24/2010 81 Male 120 lb 5/18/2011 Pharmacist United States
Primary
Secondary
Concomitant
Abdominal Pain Hospitalization 12/1/2010 57 Male 210 lb 7/20/2011 Physician United States
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 10/25/2010 64 Male 181 lb 9/4/2011 Consumer United States
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 9/29/2010 70 Male 181 lb 9/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Chest Pain 8/18/2011 60 Male 238 lb 8/30/2011 Physician United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 9/5/2011 66 Male 136 lb 9/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Urosepsis Hospitalization 9/5/2011 66 Male 137 lb 9/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Urosepsis Hospitalization 9/5/2011 66 Male 137 lb 9/16/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 7/8/2010 74 Female 152 lb 9/26/2011 Consumer United States
Primary
Secondary
Concomitant
Drug Dose Omission Hospitalization 9/5/2011 66 Male 136 lb 9/16/2011 Consumer United States
Primary
Secondary
Concomitant
Disease Progression Hospitalization 9/5/2011 66 Male 134 lb 9/28/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/5/2011 66 Male 132 lb 10/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Eosinophilia 6/30/2011 78 Female 141 lb 10/16/2011 Physician Germany
Primary
Secondary
Concomitant
Decreased Appetite Other Serious 1/1/2001 62 Male 10/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Metabolic Encephalopathy Hospitalization 9/5/2011 66 Male 137 lb 10/25/2011 Physician United States
Primary
Secondary
Concomitant
Diarrhoea Other Serious 5/14/2011 61 Female 191 lb 10/25/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Metabolic Encephalopathy Hospitalization 9/5/2011 66 Male 137 lb 11/8/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Fatigue Hospitalization 8/28/2011 58 Female 11/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cholecystitis Hospitalization 3/31/2011 64 Female 137 lb 11/28/2011 Physician Brazil
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 10/1/2011 57 Female 92 lb 12/28/2011 United States
Primary
Secondary
Concomitant
Device Related Infection Hospitalization 11/21/2010 41 Female 123 lb 2/28/2012 Physician Brazil
Primary
Secondary
Concomitant
Back Pain Hospitalization 1/1/2001 62 Male 3/6/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/25/2011 68 Female 165 lb 3/13/2012 Physician United States
Primary
Secondary
Concomitant
Cough Hospitalization 12/7/2010 51 Female 179 lb 3/27/2012 Physician Brazil
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 2/16/2012 56 Female 119 lb 3/28/2012 Physician United States
Primary
Secondary
Concomitant
Ischaemic Cerebral Infarction Hospitalization 3/30/2012 77 Male 4/6/2012 Physician Spain
Primary
Concomitant

Drug Data