Clozaril combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cardiomyopathy Hospitalization 3/17/2006 45 Male 192 lb 3/31/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Disorder Other Serious 1/16/2006 60 Female 6/8/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Somnolence Other Serious 11/16/2006 53 Female 12/27/2006 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10/1/2006 45 Male 1/3/2007 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/28/2006 44 Male 2/21/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/2/2007 42 Male 5/21/2007 Other Health Professional Australia
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 1/25/2007 38 Male 106 lb 5/31/2007 Pharmacist United Kingdom
Primary
Concomitant
Otorhinolaryngological Surgery Hospitalization 5/24/2007 48 Male 7/6/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Other Serious 1/25/2007 38 Male 106 lb 7/23/2007 Pharmacist United Kingdom
Primary
Concomitant
Vision Blurred Other Serious 6/5/2007 51 Male 8/14/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 2/26/2003 54 Male 9/20/2007 Physician Australia
Primary
Concomitant
Vomiting Other Serious 2/26/2003 54 Male 11/14/2007 Physician Australia
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 53 Female 11/21/2007 Pharmacist United Kingdom
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 12/2/2007 67 Male 1/26/2008 Pharmacist United Kingdom
Primary
Concomitant
Ventricular Extrasystoles Other Serious 12/2/2007 67 Male 2/6/2008 Pharmacist United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 3/5/2008 Male 5/27/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Other Serious 2/1/2008 Male 5/27/2008 Pharmacist United Kingdom
Primary
Concomitant
Vomiting Other Serious 11/17/2006 28 Male 6/3/2008 Physician United Kingdom
Primary
Concomitant
Interacting
Urinary Tract Infection Other Serious 3/5/2008 Male 6/11/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Other Serious 2/1/2008 Male 6/13/2008 Pharmacist United Kingdom
Primary
Concomitant
Malaise Other Serious Male 6/25/2008 Physician United Kingdom
Primary
Concomitant
Tachycardia Other Serious 4/4/2008 Male 6/25/2008 Physician United Kingdom
Primary
Concomitant
Renal Failure Other Serious 2/1/2008 Male 7/7/2008 Pharmacist United Kingdom
Primary
Concomitant
Vomiting Hospitalization 7/20/2008 Male 8/27/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/1/2008 Male 8/28/2008 Pharmacist United Kingdom
Primary
Concomitant
Urinary Incontinence Hospitalization 6/8/2007 Female 9/17/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 7/20/2008 Male 9/17/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious Male 11/6/2008 Physician United Kingdom
Primary
Concomitant
Somnolence Other Serious 9/26/2008 Male 165 lb 11/7/2008 Physician United Kingdom
Primary
Concomitant
Pulmonary Haematoma Other Serious 9/1/2008 Male 183 lb 12/1/2008 Other Health Professional New Zealand
Primary
Concomitant
Sudden Death Other Serious 11/14/2008 Male 12/1/2008 Other Health Professional United Kingdom
Primary
Concomitant
Somnolence Other Serious 9/26/2008 Male 165 lb 12/5/2008 Pharmacist United Kingdom
Primary
Concomitant
Tremor Other Serious 11/18/2008 Female 12/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Obesity Other Serious Male 12/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Hypothyroidism Other Serious 9/5/2008 Male 1/6/2009 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/29/2008 Male 1/28/2009 Other Health Professional United Kingdom
Primary
Concomitant
High Density Lipoprotein Increased Other Serious 12/30/2008 Male 1/29/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/19/2009 Male 2/13/2009 Physician United Kingdom
Primary
Concomitant
Tachycardia Other Serious 11/1/2008 Male 200 lb 2/17/2009 Pharmacist United Kingdom
Primary
Concomitant
Neutropenia Other Serious 1/15/2009 Male 3/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
Overdose Hospitalization 2/17/2009 Male 3/4/2009 Pharmacist United Kingdom
Primary
Secondary
Unresponsive To Stimuli Death 10/4/2008 44 Female 225 lb 2/9/2009 Pharmacist United States
Primary
Concomitant
Overdose Hospitalization 39 Male 3/16/2009 Pharmacist United Kingdom
Primary
Concomitant
Vomiting Other Serious Male 256 lb 3/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hypothyroidism Other Serious 9/5/2008 Male 3/23/2009 Physician United Kingdom
Primary
Concomitant
Platelet Count Decreased Other Serious 3/23/2009 Male 4/22/2009 Pharmacist United Kingdom
Primary
Concomitant
Overdose Other Serious 2/17/2009 Male 5/13/2009 Pharmacist United Kingdom
Primary
Secondary
Vulvovaginal Pruritus Other Serious 12/1/2003 43 Female 134 lb 5/20/2009 United States
Primary
Concomitant
Overdose Other Serious 2/17/2009 Male 5/25/2009 Pharmacist United Kingdom
Primary
Secondary
White Blood Cell Count Increased Other Serious 3/23/2009 Male 6/1/2009 Pharmacist United Kingdom
Primary
Concomitant
Neuropathy Peripheral Other Serious 5/5/2006 59 Male 257 lb 6/2/2009 United States
Primary
Concomitant
Multiple Drug Overdose Other Serious 2/17/2009 39 Male 5/28/2009 Physician
Primary
Concomitant
Petechiae Other Serious 4/27/2009 Male 194 lb 6/3/2009 Physician United Kingdom
Primary
Concomitant
Multiple Drug Overdose Other Serious 2/17/2009 39 Male 6/5/2009 Physician United Kingdom
Primary
Concomitant
Tachycardia Other Serious 3/1/2009 Male 6/16/2009 Pharmacist United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 5/16/2009 Male 6/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/23/2009 Male 6/29/2009 Pharmacist United Kingdom
Primary
Concomitant
Overdose Hospitalization 1/15/2009 Male 7/1/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Overdose Other Serious 6/6/2008 Male 7/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 6/23/2009 Female 7/16/2009 Pharmacist United Kingdom
Primary
Concomitant
Traumatic Lung Injury Life Threatening 7/6/2009 Male 7/23/2009 Pharmacist United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1998 41 Male 303 lb 7/30/2009 United States
Primary
Concomitant
Vomiting Other Serious 1/5/2009 Female 7/31/2009 Pharmacist United Kingdom
Primary
Concomitant
Malaise Hospitalization Female 280 lb 8/5/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/1/2009 Male 8/14/2009 Pharmacist United Kingdom
Primary
Concomitant
Sepsis Hospitalization Male 8/14/2009 Physician United Kingdom
Primary
Concomitant
Urinary Incontinence Other Serious 3/1/2008 Male 220 lb 8/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 3/23/2009 Male 8/21/2009 Pharmacist United Kingdom
Primary
Concomitant
Platelet Count Increased Other Serious 4/21/2009 Female 8/28/2009 Physician United Kingdom
Primary
Concomitant
Treatment Noncompliance Other Serious 6/6/2009 Male 9/4/2009 Pharmacist United Kingdom
Primary
Concomitant
Deep Vein Thrombosis Death Female 9/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/1/2000 45 Male 258 lb 9/23/2009 United States
Primary
Concomitant
Diabetes Mellitus Other Serious 1/1/2002 32 Female 319 lb 9/23/2009 United States
Primary
Concomitant
Postictal State Other Serious 7/13/2006 42 Female 9/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Cellulitis Hospitalization 8/6/2009 Male 9/24/2009 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/1/2009 Male 9/29/2009 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/1/2009 Male 10/16/2009 Pharmacist United Kingdom
Primary
Concomitant
Respiratory Failure Hospitalization 1/12/2009 55 Male 287 lb 10/19/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization Female 10/19/2009 Pharmacist United Kingdom
Primary
Concomitant
Peptic Ulcer Other Serious 12/3/2008 55 Male 10/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Overdose Hospitalization 1/15/2009 61 Male 10/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Peptic Ulcer Hospitalization 12/3/2008 55 Male 10/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 6/1/2008 20 Female 10/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 10/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 6/1/2008 20 10/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 10/26/2009 Pharmacist Germany
Primary
Secondary
Vomiting Hospitalization 7/20/2008 35 Male 10/26/2009 Physician United Kingdom
Primary
Concomitant
Overdose Hospitalization 1/15/2009 61 Male 10/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Breast Cancer Stage Ii Other Serious Female 10/27/2009 Physician United Kingdom
Primary
Concomitant
Respiratory Failure Hospitalization 1/12/2009 55 Male 287 lb 10/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Overdose Hospitalization 1/15/2009 61 Male 10/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 6/1/2008 20 Female 10/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 6/1/2008 20 Female 10/22/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 10/22/2009 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 10/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Multiple Drug Overdose Hospitalization 1/13/2009 61 Male 10/29/2009 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 10/30/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Peptic Ulcer Haemorrhage Other Serious 12/3/2008 55 Male 10/27/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Self Injurious Behaviour Other Serious 6/1/2008 20 Female 10/27/2009
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/30/2009 Male 11/4/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 10/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Peptic Ulcer Hospitalization 12/3/2008 55 Male 11/6/2009 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/6/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/10/2009 Pharmacist Germany
Primary
Secondary
White Blood Cell Count Increased Other Serious 3/1/2009 Male 11/11/2009 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/5/2009 United Kingdom
Primary
Secondary
Concomitant
Overdose Hospitalization 61 Male 11/5/2009 United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 20 Female 11/5/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/5/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/16/2009 Other Health Professional United Kingdom
Primary
Secondary
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/10/2009 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Peptic Ulcer Hospitalization 12/3/2008 55 Male 11/19/2009 United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Other Serious 1/1/2007 Female 11/19/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 Male 11/19/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 Male 11/19/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Peptic Ulcer Other Serious 12/3/2008 55 Male 11/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 9/30/2009 Male 11/20/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/16/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 Male 11/24/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 Male 11/24/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Respiratory Disorder Hospitalization 69 Female 11/30/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/1/2009 Pharmacist Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 39 Male 11/25/2009 Physician
Primary
Concomitant
Swelling Hospitalization Male 12/2/2009 Pharmacist United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 10/13/2009 Male 12/2/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/27/2009 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 11/17/2006 28 Male 12/1/2009 Physician United Kingdom
Primary
Concomitant
Interacting
Urinary Tract Infection Other Serious 11/10/2009 Male 12/8/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 69 Female 12/3/2009 United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/10/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Disorder Other Serious 69 Female 12/4/2009 Consumer
Primary
Secondary
Concomitant
Peptic Ulcer Other Serious 12/3/2008 55 Male 12/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 10/1/2009 Female 12/14/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 3/1/2009 Male 12/11/2009 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/15/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Ear Pain Other Serious Female 12/18/2009 Pharmacist United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/19/2008 52 Male 12/21/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/21/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 11/24/2009 Female 12/22/2009 Pharmacist United Kingdom
Primary
Concomitant
Respiratory Disorder Other Serious 69 Female 12/23/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 2/17/2009 39 Male 12/23/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/24/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 10/1/2009 57 Female 12/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant

Drug Data