Bisoprolol combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Life Threatening 9/2/2003 Male 1/4/2006 Finland
Primary
Concomitant
Sinus Bradycardia Hospitalization 12/6/2005 81 Male 154 lb 1/4/2006 United States
Primary
Secondary
Concomitant
Coronary Artery Surgery Hospitalization 4/12/2005 46 Male 192 lb 1/4/2006 United Kingdom
Primary
Secondary
Concomitant
Coronary Artery Stenosis Hospitalization 10/4/2005 70 Male 159 lb 1/12/2006 Czech Republic
Primary
Secondary
Concomitant
Sepsis Death 12/1/2005 60 Male 187 lb 1/26/2006 United Kingdom
Primary
Secondary
Concomitant
Feeling Drunk Other Serious 1/3/2005 59 Male 2/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Life Threatening 1/12/2006 76 Male 2/14/2006 Physician Netherlands
Primary
Concomitant
Sinus Bradycardia Hospitalization 12/6/2005 81 Male 154 lb 2/15/2006 Poland
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/19/2005 77 Female 115 lb 2/16/2006 Poland
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 5/9/2005 77 Male 220 lb 2/21/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Troponin Increased Hospitalization 5/9/2005 77 Male 220 lb 2/28/2006 Poland
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 1/30/2006 71 Female 3/10/2006 Pharmacist United Kingdom
Primary
Concomitant
Coronary Artery Thrombosis Life Threatening 5/19/2004 73 Male 176 lb 3/14/2006 Consumer Finland
Primary
Concomitant
Vitreous Haemorrhage Hospitalization 9/3/2005 74 Male 3/14/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Skin Cancer Life Threatening 5/9/2005 77 Male 220 lb 3/10/2006 Poland
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 76 Female 130 lb 3/24/2006 Physician Canada
Primary
Concomitant
Interacting
Renal Osteodystrophy Other Serious 1/1/2005 Female 187 lb 3/27/2006 Physician Germany
Primary
Concomitant
Cerebral Infarction Hospitalization 3/1/2006 57 Male 3/30/2006 Physician Sweden
Primary
Secondary
Concomitant
Renal Disorder Other Serious 1/1/2005 Female 187 lb 4/5/2006 Physician Germany
Primary
Concomitant
Oesophagitis Disability 1/1/2003 56 Male 198 lb 3/30/2006 United Kingdom
Primary
Secondary
Concomitant
Coronary Artery Stenosis Hospitalization 10/4/2005 70 Male 159 lb 3/31/2006 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 76 Female 130 lb 4/12/2006 Physician Canada
Primary
Concomitant
Interacting
Pre-existing Disease Other Serious 56 Male 3/30/2006 United Kingdom
Primary
Secondary
Concomitant
Nausea Hospitalization 3/20/2006 58 Female 121 lb 4/14/2006 United Kingdom
Primary
Secondary
Concomitant
Aortic Thrombosis Hospitalization 1/1/2005 65 Male 5/3/2006 Pharmacist Germany
Primary
Concomitant
Qrs Axis Abnormal Hospitalization 11/4/2005 72 Female 165 lb 5/1/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Rash Hospitalization 7/26/2004 77 Male 161 lb 5/3/2006 United States
Primary
Secondary
Concomitant
Subclavian Vein Thrombosis Hospitalization 1/25/2006 Female 141 lb 5/9/2006 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 4/2/2004 66 Female 5/5/2006 Poland
Primary
Secondary
Concomitant
Nausea Hospitalization 3/20/2006 58 Female 121 lb 5/8/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 6/27/2005 42 Male 176 lb 5/12/2006 Poland
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 12/31/2005 60 Male 165 lb 5/11/2006 United States
Primary
Secondary
Concomitant
Lacunar Infarction Hospitalization 3/1/2006 57 Male 6/8/2006 Consumer Sweden
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 11/19/2005 78 Male 196 lb 6/13/2006 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/4/2006 72 Male 176 lb 6/7/2006 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/4/2006 72 Male 176 lb 6/7/2006 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Other Serious 5/14/2006 74 Male 190 lb 6/28/2006 Consumer Netherlands
Primary
Concomitant
Cholelithiasis Hospitalization 1/14/2007 80 Male 2/19/2007 United Kingdom
Primary
Concomitant
Muscular Weakness Disability 1/19/2007 80 2/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myositis Life Threatening 6/1/2006 75 Male 139 lb 3/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Sepsis Hospitalization 12/31/2005 60 Male 165 lb 3/2/2007 Poland
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 12/5/2006 70 Male 183 lb 3/15/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Night Sweats Hospitalization 12/3/2006 70 Male 3/19/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/1997 52 Female 143 lb 3/13/2007 Physician Austria
Primary
Concomitant
Syncope Hospitalization 1/1/2007 64 Male 3/30/2007 Physician Germany
Primary
Secondary
Concomitant
Interacting
Tremor Hospitalization 3/1/2007 77 Female 3/23/2007 Physician Germany
Primary
Concomitant
Night Sweats Hospitalization 12/3/2006 70 Male 4/6/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 12/5/2006 70 Male 183 lb 4/10/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 3/7/2007 72 Male 4/4/2007 Physician United Kingdom
Primary
Concomitant
Thyroid Operation Other Serious 1/1/2005 Male 179 lb 5/7/2007 Physician Germany
Primary
Secondary
Concomitant
Vitamin B12 Decreased Other Serious 1/1/2006 78 Male 5/4/2007 Physician Finland
Primary
Concomitant
Death Hospitalization 7/13/2006 Male 159 lb 5/9/2007 United Kingdom
Primary
Concomitant
Overdose Disability 80 Female 6/29/2007 Physician United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 3/1/2005 81 Female 6/27/2007 United Kingdom
Primary
Concomitant
Urinary Retention Hospitalization 4/23/2007 Female 7/5/2007 Other Health Professional Netherlands
Primary
Concomitant
Interacting
Pleural Effusion Other Serious 6/1/2006 7/11/2007 Consumer United Kingdom
Primary
Concomitant
Ventricular Fibrillation Hospitalization 12/4/2006 Female 198 lb 7/12/2007 Physician Germany
Primary
Secondary
Concomitant
Tremor Hospitalization 75 Female 7/16/2007
Primary
Secondary
Concomitant
Inflammation Hospitalization 6/1/2007 73 Male 8/9/2007 Germany
Primary
Concomitant
Incorrect Dose Administered Hospitalization 78 Female 8/3/2007 Ireland
Primary
Secondary
Concomitant
Renal Failure Hospitalization 58 Male 8/16/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 58 Male 8/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 78 Female 8/21/2007 Ireland
Primary
Secondary
Interacting
Vitreous Haemorrhage Other Serious 12/27/2006 76 Female 148 lb 8/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Other Serious 58 Male 8/24/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Guillain-barre Syndrome Other Serious 58 Male 8/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 58 Male 8/30/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Death 8/1/2007 65 Female 8/31/2007 Other Health Professional Belgium
Primary
Concomitant
Septic Shock Hospitalization 8/15/2007 Female 170 lb 9/6/2007 United Kingdom
Primary
Concomitant
Dyspnoea Death 8/1/2007 65 Female 9/7/2007 Other Health Professional Belgium
Primary
Concomitant
Renal Failure Hospitalization 58 Male 9/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nausea Hospitalization 6/27/2005 42 Male 176 lb 8/30/2007 Other Health Professional Poland
Primary
Secondary
Concomitant
Coronary Artery Stenosis Hospitalization 11/4/2005 72 Female 165 lb 8/30/2007 Other Health Professional Poland
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 3/9/2007 79 Male 9/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 3/1/2006 Male 183 lb 9/10/2007 United Kingdom
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 3/20/2006 58 Female 121 lb 9/7/2007 United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 12/31/2005 60 Male 165 lb 9/7/2007 United States
Primary
Concomitant
Prostatic Specific Antigen Increased Hospitalization 7/7/2007 72 Male 9/7/2007 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 58 Male 9/13/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Inflammation Hospitalization 5/1/2007 Male 192 lb 9/13/2007 Germany
Primary
Concomitant
Renal Failure Other Serious 58 Male 9/14/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Somnolence Other Serious 7/1/2007 Female 249 lb 9/17/2007 Physician Germany
Primary
Concomitant
Alopecia Other Serious 3/7/2007 9/18/2007 Consumer United Kingdom
Primary
Concomitant
Psoriasis Other Serious 3/29/2007 Male 9/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Exertional Disability 7/27/2007 60 Male 163 lb 9/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Skin Infection Hospitalization 7/5/2007 Male 9/27/2007 Other Health Professional Germany
Primary
Concomitant
Rhabdomyolysis Life Threatening 7/5/2007 64 Male 9/27/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 58 Male 9/28/2007 United Kingdom
Primary
Concomitant
Interacting
Intra-abdominal Haematoma Other Serious 8/14/2007 58 Male 280 lb 9/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Thyroid Operation Other Serious 1/1/2005 Male 179 lb 10/2/2007 Pharmacist Germany
Primary
Secondary
Concomitant
Myocardial Ischaemia Death 10/31/2007 Female 183 lb 12/12/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Spinal Fusion Surgery Hospitalization 1/1/2007 70 Male 209 lb 12/18/2007 Physician Germany
Primary
Concomitant
Erythema Multiforme Other Serious 10/21/2007 79 12/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Psychosomatic Disease Hospitalization 1/1/2007 Female 176 lb 12/19/2007 Physician Germany
Primary
Concomitant
Respiratory Distress Life Threatening 5/14/2007 12/20/2007 Physician Sweden
Primary
Concomitant
Gout Hospitalization 10/26/2007 Male 260 lb 12/21/2007 Sweden
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 78 Female 12/21/2007 Ireland
Primary
Secondary
Interacting
Staphylococcal Infection Other Serious 10/1/2007 61 Female 12/27/2007 Consumer Ireland
Primary
Concomitant
Hypovolaemic Shock Other Serious 11/13/2007 85 Female 12/28/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Incorrect Dose Administered Hospitalization 78 Female 12/27/2007 Ireland
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/1999 Male 1/8/2008 Physician United Kingdom
Primary
Concomitant
Renal Failure Life Threatening 3/14/2007 Male 198 lb 1/10/2008 Physician
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 10/1/2007 61 Female 2/4/2008 Consumer Ireland
Primary
Concomitant
Musculoskeletal Discomfort Hospitalization 1/5/2008 55 Male 216 lb 2/1/2008 Physician United Kingdom
Primary
Concomitant
Loss Of Consciousness Death 1/24/2008 68 Female 154 lb 2/5/2008 Physician Russian Federation
Primary
Concomitant
Acute Myeloid Leukaemia Hospitalization 10/6/2006 Male 375 lb 5/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Tachypnoea Other Serious 63 Male 6/19/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Retinal Artery Occlusion Disability 1/7/2008 75 Male 9/14/2008 United Kingdom
Primary
Concomitant
Retinal Artery Occlusion Disability 7/1/2008 75 Male 9/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Multiple Drug Overdose Intentional Other Serious 3/9/2008 12 Female 9/29/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2008 Female 276 lb 10/6/2008 Physician Belgium
Primary
Concomitant
Interacting
Systemic Inflammatory Response Syndrome Life Threatening Male 10/13/2008 Physician Germany
Primary
Concomitant
Febrile Neutropenia Hospitalization 7/30/2007 74 Male 1/14/2009 Physician Belgium
Primary
Secondary
Concomitant
Mean Cell Volume Increased Hospitalization 9/18/2008 63 Male 176 lb 1/16/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/25/2008 74 Male 1/16/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 10/1/2008 Male 152 lb 1/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Cardiac Arrest Life Threatening 12/14/2008 Male 132 lb 1/20/2009 Pharmacist
Primary
Concomitant
Weight Decreased Other Serious 1/10/2009 Male 194 lb 1/22/2009 Physician United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Life Threatening 11/23/2008 88 Male 176 lb 1/22/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Life Threatening 11/23/2008 88 Male 176 lb 1/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/10/2009 Male 194 lb 1/23/2009 Physician United Kingdom
Primary
Concomitant
Syncope Life Threatening 5/26/2008 1/23/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/10/2009 Male 194 lb 1/23/2009 Physician United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Other Serious 11/23/2008 88 Male 1/19/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Other Serious 58 Male 1/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 1/1/2007 Male 172 lb 1/26/2009 Physician Germany
Primary
Concomitant
Renal Failure Other Serious 58 Male 1/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 12/10/2008 77 Male 1/21/2009 Netherlands
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious Female 1/27/2009 Consumer Switzerland
Primary
Concomitant
Renal Failure Other Serious 1/1/2002 1/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Interacting
Pruritus Hospitalization 7/28/2008 75 Female 144 lb 1/29/2009 Physician United Kingdom
Primary
Concomitant
Encephalitis Hospitalization 7/19/2008 1/30/2009 Other Health Professional Sweden
Primary
Concomitant
Pulmonary Embolism Life Threatening 1/21/2009 Female 2/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting 1/29/2009 Female 2/3/2009 Consumer
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2009 Male 194 lb 2/4/2009 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 8/14/2008 Female 2/4/2009 Other Health Professional France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2009 Male 194 lb 2/12/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 1/1/2008 Male 201 lb 2/12/2009 Physician Germany
Primary
Concomitant
Oedema Hospitalization 1/7/2009 65 Male 2/6/2009 Physician Finland
Primary
Concomitant
Myocardial Infarction Other Serious Male 152 lb 2/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 12/6/2008 Female 2/13/2009 Consumer United Kingdom
Primary
Concomitant
Pulmonary Embolism Life Threatening 1/21/2009 Female 2/13/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2009 Male 194 lb 2/16/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 12/10/2008 Female 187 lb 2/17/2009 Physician Germany
Primary
Concomitant
Platelet Count Decreased Hospitalization 1/16/2009 2/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 9/1/2008 69 Male 2/19/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 86 Female 2/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Non-cardiac Chest Pain Hospitalization 12/10/2008 77 Male 2/16/2009 Physician Netherlands
Primary
Secondary
Concomitant
Oedema Hospitalization 1/7/2009 65 Male 2/17/2009 Physician Finland
Primary
Concomitant
Pulmonary Embolism Life Threatening 1/21/2009 Female 2/24/2009 Consumer United Kingdom
Primary
Secondary
Concomitant

Drug Data