Simvastatin combined with Timolol Maleate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Myalgia Other Serious 43 Male 172 lb 4/12/2006 Consumer Brazil
Primary
Concomitant
Rectal Haemorrhage Required Intervention 3/23/2006 60 Male 145 lb 4/16/2006 Pharmacist United States
Primary
Concomitant
Platelet Count Increased Hospitalization 7/10/2006 76 Male 181 lb 7/21/2006 Physician Australia
Primary
Secondary
Concomitant
Platelet Count Increased Other Serious 7/10/2006 76 Male 181 lb 7/21/2006 Australia
Primary
Secondary
Concomitant
Prostatic Operation Other Serious 12/1/2002 72 Male 7/26/2006 Brazil
Primary
Concomitant
Staphylococcal Infection Hospitalization 7/10/2006 76 Male 181 lb 8/15/2006 Switzerland
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 7/10/2006 76 Male 181 lb 8/18/2006 Physician Australia
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/19/2006 77 Male 8/23/2006 Other Health Professional France
Primary
Concomitant
Lactic Acidosis Hospitalization 77 Male 8/22/2006 United Kingdom
Primary
Concomitant
Lactic Acidosis Hospitalization 77 Male 8/23/2006 United Kingdom
Primary
Concomitant
Pulmonary Calcification Hospitalization 8/2/2006 Female 165 lb 9/11/2006 Other Health Professional Romania
Primary
Secondary
Concomitant
Knee Arthroplasty Hospitalization 8/24/2006 76 Female 9/1/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Other Serious 6/14/2006 Male 9/11/2006 Pharmacist United States
Primary
Concomitant
Myocardial Ischaemia Death Female 126 lb 11/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Infection 7/10/2006 76 Male 181 lb 11/30/2006 Switzerland
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 7/10/2006 76 Male 181 lb 11/29/2006 Physician Australia
Primary
Secondary
Concomitant
Occult Blood Positive Hospitalization 12/4/2006 72 Male 291 lb 1/10/2007 Pharmacist United States
Primary
Secondary
Concomitant
Eyelids Pruritus Other Serious 10/14/2006 82 Male 162 lb 10/16/2006 Other Health Professional United States
Primary
Concomitant
Rash Other Serious 11/21/2006 81 Male 214 lb 11/24/2006 Pharmacist United States
Primary
Concomitant
Joint Swelling Other Serious 11/1/2006 61 Female 269 lb 3/23/2007 United Kingdom
Primary
Secondary
Concomitant
Joint Swelling Other Serious 11/1/2006 61 Female 269 lb 3/23/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Joint Swelling Required Intervention 11/1/2006 61 Female 3/26/2007 United Kingdom
Primary
Secondary
Concomitant
Delirium Other Serious 3/13/2007 70 Male 169 lb 3/28/2007 Pharmacist United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 76 Female 5/1/2007
Primary
Concomitant
Weight Decreased Other Serious 9/1/2003 87 Male 5/9/2007 Physician United States
Primary
Concomitant
Respiratory Arrest Other Serious 82 Female 7/6/2007 Other Health Professional Norway
Primary
Secondary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Hospitalization 82 Female 8/29/2007 Norway
Primary
Secondary
Concomitant
Blindness Unilateral Other Serious 12/1/2006 69 Male 218 lb 10/11/2007 Consumer United States
Primary
Concomitant
Weight Increased 8/1/2006 69 Female 11/14/2007 Consumer United States
Primary
Concomitant
Blindness Unilateral Other Serious 12/1/2006 69 Male 218 lb 11/20/2007 Physician United States
Primary
Concomitant
Joint Stiffness 8/1/2007 59 Female 150 lb 12/14/2007 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 82 Female 12/21/2007 Norway
Primary
Secondary
Concomitant
Interacting
Procedural Complication Life Threatening 10/1/2007 64 Male 2/22/2008 Physician Canada
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 92 Female 3/13/2008 Pharmacist Canada
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 4/11/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pollakiuria Other Serious 11/1/2007 Male 250 lb 6/18/2008 Consumer United States
Primary
Concomitant
Total Lung Capacity Decreased Other Serious 2/21/2008 Male 161 lb 6/30/2008 Physician Israel
Primary
Secondary
Concomitant
Total Lung Capacity Decreased Other Serious 2/21/2008 Male 161 lb 7/24/2008 Physician Israel
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 7/8/2006 91 Female 7/22/2008 Physician United States
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious Male 8/26/2008 United Kingdom
Primary
Concomitant
Aplasia Pure Red Cell Hospitalization 1/25/2009 Male 2/23/2009 Physician Hong Kong
Primary
Concomitant
Respiratory Failure Hospitalization 2/1/2009 Female 213 lb 3/5/2009 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 2/1/2009 Female 213 lb 3/13/2009 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 3/20/2009 Male 181 lb 4/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Drug Ineffective Other Serious 3/20/2009 Male 181 lb 4/22/2009 Consumer United Kingdom
Primary
Concomitant
Blood Pressure Increased Other Serious 3/20/2009 Male 4/22/2009 Other Health Professional United Kingdom
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 1/25/2009 Male 4/30/2009 Physician Hong Kong
Primary
Concomitant
Eyelid Ptosis Other Serious 8/4/2008 Female 134 lb 5/5/2009 Other Health Professional United States
Primary
Concomitant
Headache 3/5/2009 77 Female 5/15/2009 United States
Primary
Concomitant
Death Death 5/27/2009 Male 240 lb 6/3/2009 Physician United States
Primary
Concomitant
Coronary Artery Disease Death 5/27/2009 Male 240 lb 6/10/2009 Physician United States
Primary
Concomitant
Tremor Other Serious 5/1/2006 58 Female 6/12/2009 Other Health Professional Finland
Primary
Concomitant
Interacting
Dyspnoea 1/1/2006 Male 6/19/2009 Consumer
Primary
Concomitant
Myopathy Life Threatening 4/30/2009 77 Male 6/19/2009 United Kingdom
Primary
Concomitant
Muscle Necrosis Life Threatening 4/30/2009 77 Male 168 lb 6/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Myopathy Life Threatening 4/30/2009 77 Male 168 lb 6/22/2009
Primary
Concomitant
Urticaria Other Serious 1/18/2009 Male 202 lb 6/30/2009 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 10/11/2008 Male 7/8/2009 Other Health Professional Switzerland
Primary
Concomitant
Urine Odour Abnormal Other Serious 7/1/2009 Female 190 lb 8/21/2009 Consumer United States
Primary
Concomitant
Prostate Cancer Other Serious 65 Male 190 lb 12/15/2009 Consumer United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 12/3/2009 Female 12/29/2009 Other Health Professional United States
Primary
Concomitant
Inappropriate Schedule Of Drug Administration Hospitalization 10/26/2009 89 Female 12/21/2009 Pharmacist Canada
Primary
Concomitant
No Adverse Event 65 Male 190 lb 1/19/2010 Physician United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 12/3/2009 Female 1/27/2010 Other Health Professional United States
Primary
Concomitant
Death Hospitalization 1/11/2010 Female 218 lb 1/27/2010 Physician United States
Primary
Concomitant
Injection Site Haematoma 12/15/2008 74 Female 134 lb 2/17/2010 Other Health Professional United States
Primary
Concomitant
Hypotension Hospitalization 2/19/2010 28 Female 119 lb 6/14/2010 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 2/19/2010 27 Female 112 lb 7/1/2010 Consumer United States
Primary
Secondary
Concomitant
Vertebroplasty Other Serious 4/19/2001 81 Male 165 lb 7/7/2010 United States
Primary
Concomitant
Vertebroplasty Other Serious 4/19/2001 81 Male 165 lb 8/5/2010 United States
Primary
Concomitant
Ulcer Haemorrhage Hospitalization 1/1/2009 67 Male 229 lb 8/25/2010 Consumer United States
Primary
Concomitant
Intraocular Pressure Increased Other Serious Female 187 lb 8/20/2010 Other Health Professional Germany
Primary
Concomitant
Syncope Other Serious 8/1/2010 59 Female 125 lb 9/16/2010 Consumer United States
Primary
Concomitant
Device Issue Male 160 lb 9/20/2010 Consumer United States
Primary
Secondary
Concomitant
Tremor Other Serious 5/1/2006 58 Female 10/12/2010 Other Health Professional Finland
Primary
Concomitant
Interacting
Vertebroplasty Other Serious 4/19/2001 81 Male 165 lb 11/5/2010 United States
Primary
Concomitant
Retching Other Serious 8/1/2007 82 Female 139 lb 11/23/2010 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 11/1/2010 63 Female 100 lb 12/21/2010 Consumer United States
Primary
Concomitant
Hyperkalaemia Other Serious 1/1/2010 83 Male 2/7/2011 Physician United States
Primary
Concomitant
Hypernatraemia Hospitalization 1/26/2011 69 Male 3/15/2011 Consumer Germany
Primary
Secondary
Concomitant
Joint Dislocation Other Serious Female 178 lb 3/25/2011 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected Other Serious 12/1/2010 68 Female 3/15/2011 Consumer United States
Primary
Concomitant
Multiple Sclerosis Relapse Other Serious 12/1/2010 68 Female 105 lb 4/4/2011 Consumer United States
Primary
Concomitant
Lung Infiltration Death 79 Female 4/19/2011 United States
Primary
Concomitant
No Adverse Event 4/1/2010 79 Female 134 lb 5/4/2011 Consumer United States
Primary
Concomitant
Diarrhoea Hospitalization 1/26/2011 69 Male 5/13/2011 Consumer Germany
Primary
Secondary
Concomitant
Chest Pain 3/1/2011 79 Female 5/16/2011 Consumer United States
Primary
Concomitant
Electrolyte Imbalance Hospitalization 1/26/2011 69 Male 5/18/2011 Consumer Germany
Primary
Secondary
Concomitant
Diabetes Mellitus Other Serious Female 5/20/2011 Consumer United States
Primary
Concomitant
Pancreatitis Other Serious Female 268 lb 5/19/2011 Consumer United States
Primary
Concomitant
Hypotension Hospitalization 5/11/2011 81 Female 5/18/2011 Physician Italy
Primary
Secondary
Concomitant
Feeling Hot 11/14/2010 78 Male 6/3/2011 Physician United States
Primary
Concomitant
Nausea Hospitalization 5/11/2011 81 Female 5/20/2011 Physician Italy
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 90 Female 6/16/2011 Other Health Professional Switzerland
Primary
Concomitant
Gastritis Hospitalization 4/19/2001 81 Male 165 lb 6/20/2011 Other Health Professional United States
Primary
Concomitant
Abdominal Pain Upper 3/25/2011 84 Male 6/24/2011 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 79 Female 6/20/2011 Lawyer United States
Primary
Concomitant
Hypersensitivity Other Serious 1/1/1996 44 Female 7/12/2011 Consumer Brazil
Primary
Secondary
Concomitant
Asthenia 1/24/2011 68 Female 7/28/2011 Consumer United States
Primary
Concomitant
Proctalgia Hospitalization 4/12/2011 8/25/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Osteoarthritis Other Serious Male 8/30/2011 Other Health Professional United States
Primary
Concomitant
Aortic Valve Sclerosis Other Serious Male 9/7/2011 Other Health Professional United States
Primary
Concomitant
Mediastinal Mass Other Serious 1/1/2011 68 Male 10/12/2011 Consumer United States
Primary
Concomitant
Platelet Count Decreased Other Serious 4/21/2011 55 Female 223 lb 10/18/2011 Physician United Kingdom
Primary
Concomitant
Ischaemic Stroke Hospitalization 9/11/2011 91 Female 10/21/2011 Physician Israel
Primary
Concomitant
Asthenia Death 4/19/2001 81 Male 165 lb 10/24/2011 Physician United States
Primary
Concomitant
Neutropenic Sepsis Hospitalization 9/12/2011 68 Male 10/12/2011 Physician United Kingdom
Primary
Concomitant
Aortic Valve Incompetence Other Serious Male 10/28/2011 Lawyer United States
Primary
Concomitant
Sick Sinus Syndrome Other Serious 70 Female 11/1/2011 Physician United States
Primary
Concomitant
Erectile Dysfunction 6/1/2010 63 Male 11/1/2011 Other Health Professional United States
Primary
Concomitant
Subdural Haematoma Hospitalization 9/13/2011 91 Female 11/2/2011 Physician Israel
Primary
Concomitant
Headache 7/25/2011 75 Female 128 lb 11/3/2011 Physician United States
Primary
Concomitant
Sinus Bradycardia Other Serious 70 Female 11/11/2011 Physician United States
Primary
Concomitant
Product Quality Issue Hospitalization 3/31/2011 78 Male 156 lb 11/10/2011 Physician United States
Primary
Concomitant
Erosive Duodenitis Life Threatening 11/9/2011 67 Male 150 lb 11/28/2011 Physician Peru
Primary
Secondary
Concomitant
Acute Myocardial Infarction Hospitalization 10/11/2011 66 Male 168 lb 11/28/2011 Physician Germany
Primary
Concomitant
Muscular Weakness Hospitalization 10/3/2011 11/29/2011 Physician United States
Primary
Concomitant
Sick Sinus Syndrome Other Serious 70 Female 11/23/2011 Other Health Professional United States
Primary
Concomitant
Erosive Duodenitis Hospitalization 11/9/2011 67 Male 150 lb 12/2/2011 Physician Peru
Primary
Secondary
Concomitant
Brain Injury Hospitalization 4/28/2011 70 Female 159 lb 12/13/2011 Physician United States
Primary
Secondary
Concomitant
Pain Disability 3/31/2011 78 Male 156 lb 12/16/2011 United States
Primary
Concomitant
Carpal Tunnel Syndrome Other Serious 10/15/2011 74 Female 130 lb 12/21/2011 Consumer Brazil
Primary
Concomitant
Transmission Of An Infectious Agent Via A Medicinal Product Disability 3/31/2011 78 Male 156 lb 12/28/2011 United States
Primary
Concomitant
Blood Chloride Increased Hospitalization 12/1/2011 74 Female 972 lb 12/28/2011 United States
Primary
Secondary
Concomitant
Skin Disorder 3/1/2011 75 Male 165 lb 10/31/2011 Other Health Professional United States
Primary
Concomitant
Dry Mouth 1/1/2006 83 Female 1/3/2012 Consumer United States
Primary
Concomitant
Pancreatitis Other Serious Female 268 lb 11/17/2011 Lawyer United States
Primary
Concomitant
Drug Eruption Hospitalization 6/16/2011 66 Male 1/16/2012 Pharmacist United States
Primary
Concomitant
Dizziness Other Serious 68 Male 179 lb 1/19/2012 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Peripheral Death 10/4/2011 89 Male 1/20/2012 Physician Australia
Primary
Concomitant
Nocturia Disability 68 Male 180 lb 1/24/2012 Other Health Professional United Kingdom
Primary
Concomitant
Micturition Urgency Disability 68 Male 180 lb 1/17/2012 Other Health Professional United Kingdom
Primary
Concomitant
Dizziness Disability 68 Male 180 lb 1/25/2012 Other Health Professional United Kingdom
Primary
Concomitant
Back Pain Other Serious 1/16/2012 74 Female 126 lb 1/26/2012 Consumer United States
Primary
Concomitant
Nocturia Disability 68 Male 180 lb 1/17/2012 Other Health Professional
Primary
Concomitant
Muscle Twitching Disability 68 Male 1/23/2012 Other Health Professional Denmark
Primary
Concomitant
General Physical Health Deterioration Hospitalization 5/5/2011 77 Female 1/30/2012 Physician Italy
Primary
Secondary
Concomitant
Injection Site Pain 11/7/2011 63 Female 1/29/2012 Consumer United States
Primary
Concomitant
Injection Site Pain 8/1/2011 57 Female 1/28/2012 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization 10/4/2011 89 Male 1/31/2012 Physician Australia
Primary
Concomitant
Ventricular Hypertrophy Hospitalization Male 2/6/2012 Lawyer United States
Primary
Concomitant
Dyspnoea Hospitalization 1/9/2012 Female 2/7/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/9/2012 68 Female 154 lb 2/16/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Malignant Pleural Effusion Hospitalization 1/9/2012 68 Female 2/19/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 8/26/2011 77 Female 170 lb 3/2/2012 Physician Netherlands
Primary
Secondary
Concomitant
Anxiety Other Serious 1/9/2012 68 Female 3/2/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Respiratory Failure Hospitalization 1/9/2012 68 Female 154 lb 3/14/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Malignant Pleural Effusion Hospitalization 1/9/2012 68 Female 3/16/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Gastric Ulcer Hospitalization 1/9/2012 68 Female 154 lb 3/27/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Malignant Pleural Effusion Hospitalization 1/9/2012 68 Female 3/29/2012 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data