Capecitabine combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Loss Of Consciousness Life Threatening 1/5/2006 Female 139 lb 2/3/2006 Portugal
Primary
Concomitant
Loss Of Consciousness Life Threatening 1/5/2006 Female 139 lb 2/17/2006 Portugal
Primary
Concomitant
Tremor Life Threatening 1/5/2006 Female 139 lb 2/17/2006 Other Health Professional Portugal
Primary
Concomitant
Myocardial Infarction Hospitalization 2/5/2006 Male 2/24/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 2/16/2006 61 Female 139 lb 2/27/2006 Physician Australia
Primary
Secondary
Concomitant
Necrosis Hospitalization 2/20/2006 65 Female 152 lb 3/8/2006 Physician Austria
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/16/2006 61 Female 139 lb 3/20/2006 Physician Australia
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 65 Female 152 lb 5/12/2006 Physician Austria
Primary
Secondary
Concomitant
Troponin Increased Hospitalization 2/5/2006 Male 5/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Myocardial Infarction Death 4/28/2006 62 Female 5/30/2006 Physician Sweden
Primary
Secondary
Concomitant
Pulmonary Oedema Death 6/3/2006 75 8/3/2006 Consumer United Kingdom
Primary
Concomitant
Vomiting Life Threatening 5/13/2006 71 Female 8/8/2006 Other Health Professional Germany
Primary
Concomitant
Vomiting Hospitalization 5/5/2006 64 Male 9/18/2006 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/5/2006 64 Male 9/18/2006 Physician Netherlands
Primary
Secondary
Concomitant
Rash Hospitalization 9/22/2006 77 Female 128 lb 10/5/2006 Physician Australia
Primary
Secondary
Concomitant
Rash Hospitalization 9/22/2006 77 Male 128 lb 10/11/2006 Physician Australia
Primary
Secondary
Concomitant
Rash Hospitalization 9/22/2006 77 Male 128 lb 10/25/2006 Physician Australia
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/16/2006 Male 10/31/2006 Physician Netherlands
Primary
Secondary
Concomitant
Thrombocytopenia Death 10/16/2006 73 Male 11/6/2006 Physician Netherlands
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 5/6/2005 60 Female 11/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Lethargy Other Serious 11/6/2006 76 Female 12/13/2006 Pharmacist United Kingdom
Primary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 11/16/2006 69 Male 170 lb 3/5/2007 Physician Denmark
Primary
Secondary
Concomitant
Lethargy Hospitalization 1/30/2007 74 Male 227 lb 3/29/2007 Physician United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/30/2007 Male 4/3/2007 Physician United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/30/2007 74 Male 227 lb 4/20/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/30/2007 Male 4/25/2007 Physician United States
Primary
Secondary
Concomitant
Renal Tubular Acidosis Hospitalization 53 Male 4/30/2007 Physician United Kingdom
Primary
Concomitant
Death Death 5/2/2007 62 Male 151 lb 5/9/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death 5/2/2007 Male 151 lb 5/9/2007 Physician United States
Primary
Secondary
Concomitant
Nephrotic Syndrome Other Serious 2/20/2007 Male 5/15/2007 Physician Germany
Primary
Secondary
Concomitant
Death Death 5/2/2007 Male 151 lb 5/21/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 5/2/2007 62 Male 151 lb 5/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 65 Female 152 lb 7/12/2007 Physician Austria
Primary
Secondary
Concomitant
Septic Shock Life Threatening 7/1/2007 69 Male 132 lb 7/12/2007 Physician Spain
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 Female 152 lb 7/18/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Septic Shock Hospitalization 7/1/2007 69 Male 132 lb 7/27/2007 Physician Spain
Primary
Secondary
Concomitant
Septic Shock Hospitalization 7/1/2007 69 Male 132 lb 8/9/2007 Physician Spain
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 65 Female 152 lb 8/17/2007 Physician Austria
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 Female 152 lb 8/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 7/18/2007 Male 8/17/2007 Consumer United Kingdom
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 65 Female 152 lb 8/23/2007 Physician Austria
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 8/31/2007 74 Male 144 lb 9/14/2007 Physician United Kingdom
Primary
Secondary
Cerebral Infarction Hospitalization 11/16/2006 69 Male 170 lb 9/19/2007 Physician Denmark
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 8/31/2007 74 Male 144 lb 9/24/2007 Physician United Kingdom
Primary
Secondary
Urinary Retention Hospitalization 9/11/2004 75 Female 9/24/2007 Netherlands
Primary
Secondary
Concomitant
Sudden Death Death 9/14/2007 Male 172 lb 9/28/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 8/31/2007 Male 144 lb 9/28/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 11/16/2006 69 Male 170 lb 10/1/2007 Physician Denmark
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 8/31/2007 74 Male 144 lb 10/8/2007 Physician United Kingdom
Primary
Secondary
Pancreatitis Hospitalization 8/31/2007 Male 144 lb 10/10/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 9/14/2007 Male 172 lb 10/15/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 8/31/2007 74 Male 144 lb 10/18/2007 Physician United Kingdom
Primary
Secondary
Pancreatitis Hospitalization 8/31/2007 Male 144 lb 10/22/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Septic Shock Hospitalization 7/1/2007 69 Male 132 lb 11/2/2007 Physician Spain
Primary
Secondary
Concomitant
Fall Hospitalization 10/12/2007 74 Female 137 lb 11/12/2007 Physician Austria
Primary
Concomitant
Fall Hospitalization 10/12/2007 74 Female 137 lb 11/16/2007 Physician Austria
Primary
Concomitant
Small Intestinal Haemorrhage Death 9/14/2007 Male 172 lb 12/10/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 11/29/2007 63 Male 238 lb 12/13/2007 Physician United Kingdom
Primary
Secondary
Fall Hospitalization 10/12/2007 74 Female 137 lb 12/28/2007 Physician Austria
Primary
Concomitant
Pancreatitis Life Threatening 11/29/2007 63 Male 238 lb 2/6/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 53 Male 2/29/2008 Physician United Kingdom
Primary
Concomitant
Dehydration Hospitalization 3/7/2008 Female 4/9/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Dehydration Hospitalization 3/7/2008 Female 4/11/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Cerebral Haemorrhage Other Serious 4/16/2008 80 Male 142 lb 5/5/2008 Other Health Professional United Kingdom
Primary
Concomitant
Cheilitis Disability 4/4/2008 Female 7/1/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 5/10/2008 85 Female 163 lb 7/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intestinal Obstruction Life Threatening 6/23/2008 Female 198 lb 7/7/2008 Physician Hungary
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 5/10/2008 85 Female 7/11/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 6/26/2008 Male 7/14/2008 Physician United Kingdom
Primary
Concomitant
Diarrhoea Hospitalization 6/26/2008 Male 7/25/2008 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Hospitalization 6/18/2008 Female 130 lb 8/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Life Threatening 6/23/2008 Female 198 lb 9/2/2008 Physician Hungary
Primary
Concomitant
Thrombocytopenia Hospitalization 6/18/2008 Female 130 lb 9/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 8/24/2008 Male 9/11/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/18/2008 Female 9/12/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Sudden Death Death 8/24/2008 Male 10/7/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Acute Death 8/24/2008 Male 10/24/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2007 Male 10/31/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 9/21/2008 Male 282 lb 11/17/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 9/21/2008 Male 282 lb 12/1/2008 Physician United States
Primary
Secondary
Concomitant
Sudden Death Death 11/19/2008 Male 150 lb 12/3/2008 Physician Spain
Primary
Secondary
Concomitant
Sudden Death Death 11/19/2008 Male 150 lb 12/4/2008 Physician Spain
Primary
Secondary
Concomitant
Dyspnoea Death 11/19/2008 Male 150 lb 12/9/2008 Physician Spain
Primary
Secondary
Concomitant
Chest Pain Death 11/19/2008 Male 12/9/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 11/19/2008 Male 12/9/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Death 11/19/2008 Male 12/9/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 10/1/2008 Female 140 lb 12/22/2008 Physician United States
Primary
Concomitant
Mucosal Inflammation Death 77 Male 1/5/2009 Other Health Professional United Kingdom
Primary
Concomitant
Angina Pectoris Hospitalization 1/1/2007 Male 172 lb 1/26/2009 Physician Germany
Primary
Concomitant
Mucosal Inflammation Other Serious 77 Male 2/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
Skin Exfoliation Other Serious Female 152 lb 2/11/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 2/26/2009 73 Male 3/12/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/5/2009 52 Male 206 lb 3/10/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 2/26/2009 73 Male 3/26/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/15/2008 80 Male 127 lb 4/23/2009 Physician United States
Primary
Secondary
Concomitant
Acute Myocardial Infarction Other Serious 4/10/2009 65 Male 258 lb 5/5/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Metastases To Liver Other Serious Male 145 lb 5/8/2009 Consumer United States
Primary
Concomitant
Metastases To Abdominal Cavity Hospitalization 9/11/2004 Female 5/20/2009 Physician Netherlands
Primary
Secondary
Concomitant
Febrile Infection Hospitalization 4/24/2009 Male 5/21/2009 Physician United Kingdom
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 5/4/2009 Male 5/22/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Disease Progression Other Serious Male 145 lb 5/26/2009 Consumer United States
Primary
Concomitant
Dysaesthesia Pharynx Other Serious 1/9/2008 67 Female 5/27/2009 United Kingdom
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 5/4/2009 Male 5/28/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Nausea Hospitalization 1/1/2009 Male 6/1/2009 Consumer Canada
Primary
Concomitant
Percutaneous Coronary Intervention Hospitalization 3/23/2009 Male 6/2/2009 Consumer United States
Primary
Secondary
Concomitant
Dysaesthesia Pharynx Other Serious 1/9/2008 67 Female 6/2/2009 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/17/2008 185 lb 6/15/2009 Physician Netherlands
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 5/4/2009 Male 6/15/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 3/23/2009 Male 6/16/2009 Consumer United States
Primary
Secondary
Concomitant
Dysaesthesia Pharynx Other Serious 1/8/2008 67 Female 6/23/2009 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/17/2008 185 lb 6/25/2009 Physician Netherlands
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 6/21/2009 Male 6/30/2009 Physician Netherlands
Primary
Secondary
Concomitant
Ileus Hospitalization 9/14/2008 76 Male 194 lb 6/30/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/8/2009 Male 7/2/2009 Physician United States
Primary
Secondary
Concomitant
Febrile Infection Hospitalization 4/24/2009 Male 7/2/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 6/21/2009 68 Male 7/6/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 6/21/2009 Male 7/3/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Renal Salt-wasting Syndrome Hospitalization 7/1/2008 Male 112 lb 7/7/2009 Physician Singapore
Primary
Secondary
Concomitant
Ileus Hospitalization 9/14/2008 76 Male 194 lb 7/8/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 6/21/2009 Male 7/10/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 6/21/2009 68 Male 7/13/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Septic Shock Death 2/18/2008 Male 179 lb 7/14/2009 Consumer United Kingdom
Primary
Concomitant
Diarrhoea Hospitalization 7/4/2007 61 Female 121 lb 7/14/2009 Physician Germany
Primary
Concomitant
Ventricular Fibrillation Death 6/21/2009 Male 7/14/2009 Physician Netherlands
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 6/21/2009 68 Male 7/21/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/8/2009 Male 7/24/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 3/24/2009 Female 8/11/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 3/24/2009 Female 8/31/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Salt-wasting Syndrome Hospitalization 7/1/2008 Male 112 lb 9/1/2009 Physician Singapore
Primary
Secondary
Concomitant
Colitis Hospitalization 8/22/2009 Female 123 lb 9/14/2009 Physician Spain
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 9/10/2009 Male 250 lb 9/22/2009 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 12/18/2008 181 lb 9/24/2009 Physician Netherlands
Primary
Secondary
Concomitant
Large Intestine Perforation Life Threatening 8/22/2009 Female 123 lb 10/27/2009 Physician Spain
Primary
Secondary
Concomitant
Volvulus Life Threatening 8/22/2009 Female 123 lb 11/5/2009 Physician Spain
Primary
Secondary
Concomitant
Myocardial Infarction Death 7/27/2008 Male 199 lb 11/17/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 1/1/2007 Male 172 lb 12/1/2009 Physician Germany
Primary
Concomitant
Volvulus Hospitalization 8/22/2009 Female 123 lb 12/4/2009 Physician Spain
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Disability 8/25/2009 Female 12/14/2009 Physician Netherlands
Primary
Secondary
Concomitant
Volvulus Hospitalization 8/22/2009 Female 123 lb 12/21/2009 Physician Spain
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 12/5/2009 Female 146 lb 12/22/2009 Physician Belgium
Primary
Secondary
Concomitant
Volvulus Hospitalization 8/22/2009 Female 123 lb 12/24/2009 Physician Spain
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/5/2009 Female 146 lb 12/31/2009 Physician Belgium
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 9/24/2008 51 Male 12/22/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Volvulus Life Threatening 8/22/2009 Female 123 lb 1/6/2010 Physician Spain
Primary
Secondary
Concomitant
Encephalopathy Hospitalization 79 Male 1/11/2010 Physician United States
Primary
Concomitant
Oesophagitis Hospitalization 12/5/2009 Female 146 lb 1/19/2010 Physician Belgium
Primary
Secondary
Concomitant
Anal Abscess Life Threatening 10/29/2009 79 Male 173 lb 1/18/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Anal Abscess Life Threatening 10/29/2009 79 Male 173 lb 1/29/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Phlebitis Other Serious 6/6/2009 Female 150 lb 2/8/2010 Consumer United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 12/5/2009 Female 146 lb 2/8/2010 Physician Belgium
Primary
Secondary
Concomitant

Drug Data