Simvastatin combined with Vincristine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Coronary Artery Disease Life Threatening 12/14/2004 61 Female 198 lb 6/2/2006 Other Health Professional South Africa
Primary
Secondary
Concomitant
Oral Candidiasis Hospitalization 7/18/2003 62 Male 175 lb 6/20/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/20/2003 62 Male 6/16/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/18/2003 62 Male 175 lb 6/16/2006 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/18/2003 62 Male 6/20/2006 Physician United States
Primary
Secondary
Concomitant
Coronary Artery Disease Life Threatening 12/14/2004 61 Female 198 lb 7/5/2006 Physician South Africa
Primary
Secondary
Concomitant
Hypoaesthesia Hospitalization 8/9/2006 69 Male 155 lb 8/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Polyneuropathy Hospitalization 67 Male 168 lb 11/7/2006 Physician France
Primary
Concomitant
Pneumonia Hospitalization 1/3/2007 53 Male 179 lb 2/12/2007 Physician Israel
Primary
Secondary
Concomitant
Septic Shock Other Serious 73 Female 4/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 73 Female 5/3/2007
Primary
Secondary
Concomitant
White Blood Cell Count Decreased 4/28/2007 69 Female 4/29/2007 United States
Primary
Concomitant
Septic Shock Hospitalization 73 Female 11/6/2007 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 2/11/2008 Female 2/29/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/8/2007 Female 120 lb 3/25/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 11/28/2007 Female 120 lb 3/25/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 11/8/2007 Female 120 lb 4/11/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/28/2007 Female 120 lb 4/11/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 12/21/2007 Female 265 lb 4/11/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Stomatitis Hospitalization 11/8/2007 Female 120 lb 4/25/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/8/2007 Female 120 lb 7/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/11/2008 Female 8/6/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/28/2007 Female 120 lb 8/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Vision Blurred Other Serious 8/24/2008 76 Female 10/20/2008 Other Health Professional Belgium
Primary
Concomitant
Respiratory Distress Other Serious 9/17/2008 63 Male 168 lb 10/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vision Blurred Other Serious 8/24/2008 76 Female 11/25/2008 Other Health Professional Belgium
Primary
Concomitant
Panic Attack Other Serious Male 12/22/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 12/10/2008 62 Male 116 lb 1/22/2009 Physician United States
Primary
Secondary
Concomitant
Leukoencephalopathy Death Female 2/27/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Leukoencephalopathy Death 5/1/2008 64 Female 3/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Lacunar Infarction Other Serious 8/24/2008 76 Female 3/19/2009 Other Health Professional Belgium
Primary
Concomitant
Infection Hospitalization 3/18/2009 Female 4/3/2009 Physician United Kingdom
Primary
Concomitant
Pain Hospitalization 3/27/2009 Female 163 lb 4/8/2009 Physician
Primary
Secondary
Concomitant
Pain Hospitalization 3/27/2009 84 Female 163 lb 4/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Hospitalization 3/27/2009 Female 164 lb 4/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 3/27/2009 Female 163 lb 4/27/2009 Physician
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2009 84 Female 163 lb 4/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Hospitalization 3/27/2009 Female 164 lb 5/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Infection Hospitalization 3/18/2009 Female 5/18/2009 Physician United Kingdom
Primary
Concomitant
Dehydration Hospitalization 5/20/2009 Male 6/18/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Infection Hospitalization 3/18/2009 Female 7/2/2009 Physician United Kingdom
Primary
Concomitant
Panic Attack Other Serious Male 7/24/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Panic Attack Other Serious Male 8/11/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 9/1/2009 Female 145 lb 9/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Life Threatening 9/3/2009 Female 10/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Urticaria Other Serious 9/1/2009 Male 10/28/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 9/1/2009 Female 145 lb 10/28/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiomyopathy Other Serious 2/6/2008 Female 11/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiomyopathy Other Serious 2/6/2008 Female 143 lb 12/22/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Dehydration Hospitalization 5/20/2009 Male 180 lb 2/19/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 3/31/2010 80 Male 154 lb 5/14/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/26/2010 77 Male 160 lb 5/25/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 9/27/2009 75 Male 201 lb 6/3/2010 Physician
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 8/1/2001 63 Male 6/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vitamin B12 Deficiency Other Serious 1/16/2004 59 Male 6/11/2010 United States
Primary
Concomitant
General Physical Health Deterioration Hospitalization 3/31/2010 80 Male 154 lb 6/18/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 8/1/2001 63 Male 6/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 1/1/2009 73 Female 7/2/2010 Physician Finland
Primary
Concomitant
Interacting
Death Death 6/11/2010 69 Female 207 lb 7/7/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypotension Hospitalization 6/11/2010 69 Female 207 lb 7/14/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Vitamin B12 Deficiency Other Serious 1/16/2004 59 Male 7/14/2010 United States
Primary
Concomitant
White Blood Cell Count Abnormal Other Serious 12/9/2008 51 Male 7/15/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Dehydration Hospitalization 6/12/2010 56 Male 141 lb 7/15/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Hypotension Hospitalization 6/11/2010 69 Female 207 lb 8/3/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/1/1998 52 Female 8/5/2010 United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/1/1998 52 Female 8/20/2010 United States
Primary
Secondary
Concomitant
Vertigo Other Serious 7/4/2010 60 Female 150 lb 9/14/2010 Physician United States
Primary
Secondary
Concomitant
Sudden Death Death 9/5/2010 74 Male 185 lb 9/17/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 8/18/2010 67 Male 9/22/2010 Physician Germany
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 8/18/2010 67 Male 190 lb 9/24/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/1/1998 52 Female 9/29/2010 United States
Primary
Secondary
Concomitant
Neutropenic Infection Death 9/25/2010 84 Male 19 lb 10/8/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Other Serious 9/25/2010 84 Male 187 lb 10/12/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vertigo Other Serious 7/4/2010 60 Female 150 lb 10/19/2010 Physician United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 4/26/2010 10/27/2010 United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 4/26/2010 73 Female 174 lb 10/29/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Vertigo Other Serious 7/4/2010 60 Female 150 lb 11/5/2010 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Death 9/25/2010 84 Male 19 lb 11/8/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 9/25/2010 84 Male 187 lb 11/8/2010 Physician United Kingdom
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/1/1998 52 Female 11/9/2010 United States
Primary
Secondary
Concomitant
Pneumonia Life Threatening 9/28/2010 78 Male 194 lb 11/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Neurotoxicity Hospitalization 6/1/2007 56 Female 11/9/2010 Physician Germany
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 10/1/2010 73 Male 207 lb 11/18/2010 Physician United Kingdom
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/25/1998 52 Female 11/29/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/12/2010 56 Male 141 lb 12/15/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/25/1998 52 Female 12/21/2010 United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 9/25/2010 84 Male 187 lb 12/23/2010 Physician United Kingdom
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/25/1998 52 Female 12/30/2010 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 9/27/2010 73 Male 185 lb 1/7/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 6/12/2010 56 Male 141 lb 1/7/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 9/27/2010 73 Male 185 lb 1/26/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Infection Disability 10/6/2010 72 Female 143 lb 2/11/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Life Threatening 10/1/2010 73 Male 207 lb 2/23/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Epistaxis Hospitalization 12/25/2010 64 Male 237 lb 1/25/2011 Pharmacist United States
Primary
Concomitant
Pancytopenia Death 9/25/2010 84 Male 19 lb 2/28/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Otitis Media Chronic Hospitalization 1/25/1998 52 Female 3/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 1/25/1998 52 Female 3/29/2011 Lawyer United States
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 10/6/2010 72 Female 143 lb 4/29/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
T-cell Lymphoma Other Serious 2/15/2011 64 Male 222 lb 6/9/2011 Physician United States
Primary
Secondary
Concomitant
T-cell Lymphoma Hospitalization 2/15/2011 64 Male 222 lb 6/29/2011 Consumer United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 8/7/2004 60 Male 7/5/2011 Consumer United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 4/29/2010 70 Female 183 lb 7/12/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 2/15/2011 64 Male 222 lb 7/21/2011 Physician United States
Primary
Secondary
Concomitant
Proctalgia Hospitalization 4/12/2011 8/25/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 4/29/2010 70 Female 183 lb 8/25/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Petechiae Other Serious 1/1/2011 87 Male 238 lb 9/20/2011 Physician United States
Primary
Concomitant
Fall Other Serious Male 9/21/2011 Physician United States
Primary
Secondary
Concomitant
Aortic Aneurysm Other Serious 11/1/2008 83 Male 9/21/2011 Lawyer United States
Primary
Concomitant
Angina Unstable Other Serious Male 11/2/2011 Physician United States
Primary
Secondary
Concomitant
Stasis Dermatitis Other Serious 1/1/2011 88 Male 238 lb 11/8/2011 Other Health Professional United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 11/1/2008 83 Male 11/10/2011 Lawyer United States
Primary
Concomitant
Ejection Fraction Decreased Other Serious Male 11/17/2011 Lawyer United States
Primary
Secondary
Concomitant
Oral Cavity Fistula Hospitalization 1/25/1998 52 Female 11/17/2011 Physician United States
Primary
Secondary
Concomitant
Petechiae Other Serious 1/1/2011 88 Male 238 lb 11/21/2011 Physician United States
Primary
Concomitant
Arteriovenous Fistula Site Complication Disability 1/25/1998 52 Female 11/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 9/1/2011 68 Female 195 lb 11/23/2011 Physician United States
Primary
Concomitant
Dysaesthesia Other Serious Male 12/2/2011 Lawyer United States
Primary
Secondary
Concomitant
Myeloma Recurrence Disability 1/25/1998 52 Female 12/2/2011 Consumer United States
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 11/4/2011 69 Male 12/1/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Atelectasis Other Serious 71 Male 12/14/2011 Lawyer United States
Primary
Concomitant
Spinal Deformity Hospitalization 9/21/2011 73 Female 192 lb 12/29/2011 United Kingdom
Primary
Secondary
Concomitant
Musculoskeletal Chest Pain Hospitalization 11/1/2008 83 Male 1/30/2012 Physician United States
Primary
Concomitant
Fall Hospitalization 3/27/2009 84 Female 154 lb 2/13/2012 Physician United States
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 8/18/2008 78 Male 198 lb 2/15/2012 Germany
Primary
Secondary
Concomitant
Oral Candidiasis Hospitalization 1/30/2012 78 Female 141 lb 2/17/2012 Physician Denmark
Primary
Secondary
Concomitant
Fatigue Death 11/1/2008 83 Male 2/20/2012 Physician United States
Primary
Concomitant
Oral Candidiasis Hospitalization 1/30/2012 78 Female 141 lb 2/21/2012 Physician Denmark
Primary
Secondary
Concomitant
Fall Hospitalization 9/11/2011 86 Female 154 lb 2/23/2012 United States
Primary
Secondary
Concomitant
Enterocolitis Haemorrhagic Hospitalization 12/13/2011 79 Female 170 lb 2/23/2012 Physician Germany
Primary
Concomitant
Oral Candidiasis Hospitalization 1/30/2012 78 Female 141 lb 2/24/2012 Physician Denmark
Primary
Secondary
Concomitant
Oral Candidiasis Hospitalization 1/30/2012 78 Female 141 lb 2/27/2012 Denmark
Primary
Secondary
Concomitant
Dehydration Hospitalization 1/16/2012 78 Female 141 lb 2/27/2012 Denmark
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/30/2012 78 Female 141 lb 2/28/2012 Physician Denmark
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/30/2012 78 Female 141 lb 2/29/2012 Physician Denmark
Primary
Secondary
Concomitant
Infection Hospitalization 2/14/2012 Male 2/29/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Dehydration Hospitalization 1/16/2012 78 Female 141 lb 2/29/2012 Physician Denmark
Primary
Secondary
Concomitant
Femoral Neck Fracture Hospitalization 3/27/2009 84 Female 154 lb 3/2/2012 Physician United States
Primary
Secondary
Concomitant
Oral Candidiasis Hospitalization 1/30/2012 78 Female 141 lb 3/2/2012 Physician Denmark
Primary
Secondary
Concomitant
Infection Hospitalization 2/14/2012 Male 3/12/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/30/2012 78 Female 141 lb 3/12/2012 Physician Denmark
Primary
Secondary
Concomitant
Cough Hospitalization 2/28/2012 3/13/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Dehydration Hospitalization 1/16/2012 78 Female 141 lb 3/16/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant
Femoral Neck Fracture Hospitalization 9/11/2011 86 Female 154 lb 3/16/2012 United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 1/25/1998 52 Female 3/16/2012 Consumer United States
Primary
Secondary
Concomitant
Oral Candidiasis Hospitalization 1/30/2012 78 Female 141 lb 3/19/2012 Physician Denmark
Primary
Secondary
Concomitant
Dehydration Hospitalization 1/16/2012 78 Female 141 lb 3/20/2012 Physician Denmark
Primary
Secondary
Concomitant
Back Pain Hospitalization 11/1/2008 83 Male 3/22/2012 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 2/28/2012 3/23/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Cataract Disability 1/25/1998 52 Female 3/26/2012 Lawyer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/16/2012 78 Female 141 lb 3/27/2012 Physician Denmark
Primary
Secondary
Concomitant

Drug Data