Avandia combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Respiratory Disorder Other Serious 79 Male 156 lb 1/20/2006 Physician Canada
Primary
Secondary
Concomitant
Oral Discomfort Other Serious 11/1/2005 47 Female 150 lb 1/31/2006 Consumer Brazil
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/28/2005 Male 197 lb 2/1/2006 United States
Primary
Secondary
Concomitant
Swelling 7/1/2004 60 Female 115 lb 1/25/2006 Other Health Professional United States
Primary
Concomitant
Dysgeusia 12/3/2005 76 Female 130 lb 1/5/2006 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 81 Male 3/6/2006 Consumer Germany
Primary
Concomitant
Visual Acuity Reduced Other Serious 81 Male 3/17/2006 Physician Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 6/27/2005 76 Female 3/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Other Serious 1/1/2005 78 Male 170 lb 3/2/2006 United States
Primary
Concomitant
Oral Discomfort Other Serious 11/1/2005 47 Female 150 lb 3/22/2006 Physician Brazil
Primary
Secondary
Concomitant
Thrombocytopenia Death 3/15/2005 62 Male 3/27/2006 Physician Canada
Primary
Secondary
Concomitant
Portal Hypertensive Gastropathy Hospitalization 1/1/2006 62 Female 3/29/2006 Consumer Denmark
Primary
Concomitant
Oedema Other Serious 5/25/2005 Male 4/3/2006 Physician Sweden
Primary
Concomitant
Psychotic Disorder Other Serious 8/30/2004 70 Male 4/5/2006 Physician Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/1/2003 67 Female 190 lb 4/6/2006 Physician United States
Primary
Concomitant
Visual Disturbance Other Serious 48 Male 240 lb 4/27/2006 Physician United Kingdom
Primary
Concomitant
Myocardial Infarction Death 87 Male 5/3/2006 Pharmacist Canada
Primary
Concomitant
Myocardial Infarction Death 87 Male 5/3/2006 Pharmacist Canada
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 9/1/2005 68 Male 4/27/2006 Brazil
Primary
Secondary
Concomitant
Myocardial Infarction Death 87 Male 5/5/2006 Consumer Canada
Primary
Concomitant
Myocardial Infarction Death 87 Male 5/5/2006 Consumer Canada
Primary
Concomitant
Varicella Hospitalization 8/29/2000 62 Female 5/11/2006 Consumer Denmark
Primary
Concomitant
Oedema Other Serious 3/13/2006 80 Male 162 lb 5/17/2006 Physician Canada
Primary
Concomitant
Varicella Hospitalization 8/29/2000 62 Female 5/25/2006 Consumer Denmark
Primary
Concomitant
White Blood Cell Disorder Other Serious 1/16/2006 60 Female 6/8/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Neuropathy Other Serious 79 Male 162 lb 4/20/2006 United States
Primary
Secondary
Concomitant
Normochromic Normocytic Anaemia Other Serious 1/1/2006 70 Male 6/19/2006 Physician Spain
Primary
Secondary
Concomitant
Panic Attack 3/1/2006 56 Female 5/23/2006 Consumer United States
Primary
Concomitant
Influenza Like Illness 12/1/2005 70 Male 7/21/2006 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 8/1/2005 78 Male 7/21/2006 Consumer United States
Primary
Concomitant
Thrombosis In Device Hospitalization 6/2/2006 36 Female 334 lb 8/18/2006 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Other Serious 7/20/2006 70 Male 335 lb 9/7/2006 Consumer United States
Primary
Concomitant
Hyperhidrosis 5/31/2006 62 Male 284 lb 7/19/2006 Consumer United States
Primary
Concomitant
Pulmonary Granuloma Life Threatening 1/1/2006 40 Male 10/25/2006 Physician Iceland
Primary
Secondary
Concomitant
Weight Increased Hospitalization 9/21/2006 78 Male 212 lb 11/2/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/12/2006 58 Female 205 lb 11/20/2006 Physician United States
Primary
Secondary
Concomitant
Sarcoidosis Life Threatening 1/1/2006 40 Male 11/27/2006 Physician Switzerland
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Disability 7/24/2006 43 Male 148 lb 12/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Macular Degeneration Other Serious 5/1/2006 Female 12/11/2006 Brazil
Primary
Concomitant
Middle Insomnia 5/1/2005 69 Male 176 lb 10/11/2006 Consumer United States
Primary
Concomitant
Sick Sinus Syndrome Other Serious 8/14/2006 Female 199 lb 1/10/2007 Physician United States
Primary
Concomitant
Syncope Hospitalization 9/1/2006 67 Male 153 lb 1/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Insomnia 1/1/2006 77 Female 174 lb 10/24/2006 United States
Primary
Concomitant
Respiratory Disorder Other Serious 79 Male 1/15/2007 Physician Canada
Primary
Secondary
Concomitant
Respiratory Disorder Other Serious 79 Male 1/16/2007 Physician Canada
Primary
Secondary
Concomitant
Rash Hospitalization 7/14/2006 63 Male 181 lb 10/20/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased 1/1/2005 72 Male 182 lb 10/16/2006 Consumer United States
Primary
Secondary
Concomitant
Blindness Other Serious 12/1/2006 Male 1/29/2007 Consumer United States
Primary
Concomitant
Urticaria Hospitalization 3/1/2006 65 Male 241 lb 2/9/2007 Physician United States
Primary
Secondary
Concomitant
Waist Circumference Increased Hospitalization 1/22/2007 82 Male 3/1/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Nodule Other Serious 71 Male 3/27/2007 Physician Brazil
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 241 lb 4/11/2007 Consumer United States
Primary
Concomitant
Multiple Fractures Hospitalization 12/1/2006 71 Female 154 lb 4/6/2007 Physician Germany
Primary
Concomitant
Upper Limb Fracture Required Intervention 70 Female 143 lb 4/6/2007 Physician Germany
Primary
Concomitant
Weight Decreased 11/1/2006 61 Female 198 lb 1/12/2007 Consumer United States
Primary
Secondary
Concomitant
Urticaria Life Threatening 3/1/2006 65 Male 241 lb 4/25/2007 Physician United States
Primary
Secondary
Concomitant
Radius Fracture Other Serious 3/24/2007 57 Female 212 lb 5/8/2007 Physician Germany
Primary
Concomitant
Respiratory Disorder Other Serious 9/1/2005 79 Male 5/14/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Pancreatitis Relapsing Hospitalization 4/21/2007 71 Male 229 lb 5/15/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 71 Male 5/16/2007 Physician United Kingdom
Primary
Concomitant
Spinal Fracture Hospitalization 66 Male 5/25/2007 Consumer United States
Primary
Concomitant
Muscle Spasms 5/1/2006 63 Male 3/13/2007 Consumer United States
Primary
Concomitant
Pulmonary Oedema Other Serious 6/1/2006 71 Male 229 lb 5/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rales Other Serious 5/8/2007 75 Male 159 lb 6/4/2007 Physician United Kingdom
Primary
Concomitant
Pneumonia Other Serious 10/1/2004 76 Male 6/11/2007 Consumer United States
Primary
Concomitant
Macular Oedema Other Serious 74 Female 6/11/2007 Consumer Canada
Primary
Concomitant
Pulmonary Hypertension Other Serious 6/1/2002 63 Male 269 lb 6/12/2007 Consumer United States
Primary
Concomitant
Urticaria Other Serious 5/18/2007 Male 6/18/2007 Physician Finland
Primary
Concomitant
Pulmonary Oedema Other Serious 6/1/2006 71 Male 229 lb 6/20/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Erythematous Other Serious 1/11/2007 Male 211 lb 6/26/2007 Physician United States
Primary
Concomitant
Hypoglycaemia Other Serious 3/11/2007 73 Female 4/26/2007 United States
Primary
Secondary
Concomitant
Mobility Decreased Other Serious 1/19/2007 73 Male 211 lb 4/26/2007 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/8/2007 71 Male 142 lb 6/28/2007 Physician United Kingdom
Primary
Concomitant
Hypoglycaemia Life Threatening 1/6/2007 51 Female 191 lb 4/26/2007 Physician United States
Primary
Secondary
Concomitant
Rash Other Serious 2/22/2006 34 Female 290 lb 5/22/2007 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 65 Female 7/11/2007 Consumer United States
Primary
Concomitant
Paraesthesia Other Serious 6/3/2007 59 Female 160 lb 7/9/2007 Consumer United States
Primary
Concomitant
Urticaria Other Serious 5/18/2007 Male 7/16/2007 Physician Finland
Primary
Concomitant
Therapeutic Response Unexpected Male 220 lb 7/23/2007 Physician United States
Primary
Concomitant
Sinus Operation 3/1/2006 Male 7/23/2007 Consumer United States
Primary
Concomitant
Weight Increased Disability 58 Male 327 lb 7/23/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 82 7/23/2007 Consumer United States
Primary
Concomitant
Weight Increased 1/1/2006 80 Male 7/23/2007 Consumer United States
Primary
Concomitant
Dizziness 73 Female 7/23/2007 Consumer United States
Primary
Concomitant
Palpitations Female 7/23/2007 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 1/1/2006 88 Female 7/23/2007 Consumer United States
Primary
Concomitant
Temperature Intolerance Other Serious 6/3/2007 59 Female 160 lb 7/20/2007 Consumer United States
Primary
Concomitant
Stomach Discomfort 10/17/2006 Female 262 lb 7/26/2007 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 65 Female 8/8/2007 Consumer United States
Primary
Concomitant
Percutaneous Coronary Intervention Hospitalization 7/26/2007 72 Male 164 lb 8/14/2007 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 6/22/2007 30 Female 176 lb 8/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 1/1/2007 73 Female 8/24/2007 Consumer United States
Primary
Concomitant
Stent Placement Hospitalization Male 8/24/2007 Consumer United States
Primary
Concomitant
Cardiac Failure Acute Death 65 Female 190 lb 8/30/2007 Consumer United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 65 Female 9/4/2007 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 6/16/2007 84 Female 9/5/2007 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Death 4/1/2007 68 Female 190 lb 8/28/2007 Pharmacist United States
Primary
Concomitant
Orthopnoea Hospitalization 1/1/2006 88 Female 106 lb 9/11/2007 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 65 Female 276 lb 9/20/2007 Consumer United States
Primary
Concomitant
Pelvic Pain 7/27/2007 63 Female 159 lb 9/26/2007 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 6/18/2007 83 Female 187 lb 9/27/2007 Physician United States
Primary
Concomitant
Skin Exfoliation Other Serious 5/17/2007 57 Male 209 lb 9/27/2007 Norway
Primary
Concomitant
Faeces Discoloured Other Serious Male 10/4/2007 Pharmacist United Kingdom
Primary
Concomitant
Weight Decreased 61 Female 198 lb 10/4/2007 Consumer United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 5/1/2007 68 Male 198 lb 10/5/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 251 lb 10/5/2007 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 5/1/2007 68 Male 198 lb 10/22/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/1/2004 76 Male 10/23/2007 Consumer United States
Primary
Concomitant
Insomnia Death 3/20/2007 71 Male 10/26/2007 Consumer Netherlands
Primary
Concomitant
Rectal Haemorrhage Other Serious 12/1/2006 69 Male 11/5/2007 Physician United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 11/1/2005 77 Female 11/5/2007 Consumer United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 6/13/2006 Female 11/6/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 44 Male 11/8/2007 Pharmacist Korea, Republic Of
Primary
Concomitant
Myocardial Infarction Hospitalization 6/13/2006 Female 11/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 6/13/2006 Female 11/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Intracardiac Thrombus Life Threatening 8/19/2007 58 Male 11/27/2007 Consumer Denmark
Primary
Concomitant
Myocardial Infarction Hospitalization 4/29/2007 24 Female 243 lb 12/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased 1/1/2006 52 Female 197 lb 10/9/2007 Consumer United States
Primary
Concomitant
Pleural Effusion Hospitalization 1/1/2007 72 Male 12/13/2007 Consumer United Kingdom
Primary
Concomitant
Weight Decreased 1/1/2005 72 Male 182 lb 10/9/2007 Consumer United States
Primary
Concomitant
Pleural Effusion Other Serious 8/31/2007 71 Female 12/18/2007 Physician Finland
Primary
Concomitant
Rectal Haemorrhage Other Serious 12/1/2006 69 Male 204 lb 12/20/2007 Physician United Kingdom
Primary
Concomitant
Pleural Effusion Other Serious 8/1/2007 71 Female 12/21/2007 Physician Finland
Primary
Concomitant
Oedema Peripheral Other Serious 11/1/2007 74 Female 207 lb 12/28/2007 Physician United Kingdom
Primary
Concomitant
Pulmonary Oedema Death 7/1/2007 84 Male 220 lb 1/17/2008 Physician United Kingdom
Primary
Concomitant
Palpitations Hospitalization 8/4/2007 79 Male 1/23/2008 Physician United States
Primary
Concomitant
Oesophageal Pain Other Serious 1/29/2008 Male 250 lb 2/5/2008 Pharmacist United States
Primary
Concomitant
Hepatic Steatosis Hospitalization 10/1/2007 53 Male 194 lb 2/7/2008 Consumer France
Primary
Secondary
Concomitant
Ischaemia Death 12/16/2007 67 Male 231 lb 2/14/2008 Physician United Kingdom
Primary
Concomitant
Sepsis Death 10/13/2007 83 Female 159 lb 2/20/2008 Physician Belgium
Primary
Concomitant
Pollakiuria Required Intervention 1/1/2000 Male 2/21/2008 United States
Primary
Secondary
Concomitant
Weight Decreased 1/1/2005 72 Male 182 lb 1/10/2008 Consumer United States
Primary
Concomitant
Vitamin D Deficiency 1/1/2007 58 Female 1/10/2008 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/8/2008 50 Female 216 lb 3/7/2008 Physician United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 3/4/2008 64 Female 3/19/2008 Consumer Norway
Primary
Concomitant
Blood Glucose Increased Other Serious 3/24/2008 Female 144 lb 4/8/2008 United States
Primary
Concomitant
Renal Pain Hospitalization Female 4/17/2008 Consumer United States
Primary
Concomitant
Suicidal Ideation Other Serious 3/24/2008 Female 145 lb 4/21/2008 United States
Primary
Concomitant
Weight Increased Hospitalization 66 Female 4/29/2008 Consumer United States
Primary
Concomitant
Chromaturia Other Serious 1/7/2008 58 Female 205 lb 5/5/2008 Consumer United States
Primary
Secondary
Concomitant
Nausea Other Serious 2/19/2008 80 Female 163 lb 5/16/2008 Physician Germany
Primary
Concomitant
Sudden Death Death 74 Male 5/23/2008 Consumer Norway
Primary
Concomitant
Suicidal Ideation Other Serious 3/24/2008 Female 148 lb 5/30/2008 United States
Primary
Secondary
Concomitant
Vision Blurred 4/1/2008 67 Female 156 lb 5/5/2008 Physician United States
Primary
Concomitant
Nausea 3/7/2008 73 Male 4/10/2008 Consumer United States
Primary
Concomitant
Hypoaesthesia 3/14/2008 58 Female 4/10/2008 Consumer United States
Primary
Concomitant
Suicidal Ideation Other Serious 3/24/2008 Female 148 lb 6/16/2008 United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1/1/2001 Male 326 lb 6/17/2008 Other Health Professional United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 8/25/2006 59 Male 6/18/2008 Physician United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 1/1/2002 61 Male 6/19/2008 Physician United States
Primary
Concomitant

Drug Data