Lamotrigine combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tremor Hospitalization 2/7/2006 65 Male 157 lb 5/2/2006 Pharmacist United States
Primary
Concomitant
Post Procedural Complication Hospitalization 3/29/2006 66 Male 5/5/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Hospitalization 3/29/2006 66 Male 5/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypoaesthesia Hospitalization 1/31/2006 48 Male 268 lb 2/7/2006 Pharmacist United States
Primary
Secondary
Disorientation Other Serious 7/10/2005 77 Male 5/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 3/29/2006 67 Female 6/14/2006 Other Health Professional Denmark
Primary
Concomitant
Death Death 3/29/2006 67 Female 6/28/2006 Other Health Professional Denmark
Primary
Concomitant
Urine Ketone Body Present Other Serious 12/1/2005 Female 12/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatitis Hospitalization 12/7/2006 47 Female 191 lb 1/18/2007 Pharmacist United States
Primary
Concomitant
Mania Hospitalization 1/1/1994 Male 3/5/2007 Consumer France
Primary
Concomitant
Mania Hospitalization 1/1/1994 Male 3/14/2007 Physician France
Primary
Concomitant
Vomiting Hospitalization 11/1/2005 49 Female 160 lb 1/18/2007 Physician United States
Primary
Concomitant
Tremor Other Serious 9/14/2007 75 Male 146 lb 11/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Homicide Other Serious 8/24/2007 Male 11/14/2007 Physician United Kingdom
Primary
Concomitant
Tremor Life Threatening 9/14/2007 75 Male 146 lb 11/15/2007 Pharmacist United Kingdom
Primary
Concomitant
Interacting
Obstructive Airways Disorder Life Threatening 9/14/2007 75 Male 146 lb 11/16/2007 United Kingdom
Primary
Secondary
Concomitant
Tremor Life Threatening 9/14/2007 75 Male 11/16/2007 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/15/2008 Female 2/27/2008 Physician Germany
Primary
Secondary
Vomiting Hospitalization 2/15/2008 Female 3/3/2008 Physician Germany
Primary
Secondary
Withdrawal Syndrome Other Serious 45 Male 2/29/2008 United States
Primary
Concomitant
Pain 1/1/2008 Female 118 lb 6/12/2008 Consumer United States
Primary
Concomitant
Malaise Other Serious Male 6/25/2008 Physician United Kingdom
Primary
Concomitant
Withdrawal Syndrome Other Serious 45 Male 6/27/2008 United States
Primary
Concomitant
Personality Change Hospitalization 2/22/2003 54 Male 8/8/2008 Consumer Denmark
Primary
Secondary
Concomitant
Vomiting Life Threatening 5/12/2008 46 Female 8/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Personality Change Hospitalization 2/22/2003 54 Male 8/13/2008 Consumer Denmark
Primary
Secondary
Concomitant
Immobile Other Serious 11/15/2007 Female 8/15/2008 Physician France
Primary
Concomitant
Vomiting Life Threatening 46 Female 8/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Burning Sensation 7/16/2008 Female 8/29/2008 United States
Primary
Concomitant
Personality Change Hospitalization 2/22/2003 54 Male 9/4/2008 Consumer Denmark
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/25/2008 76 Female 118 lb 9/4/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 8/24/2008 76 Female 118 lb 9/10/2008 Physician United States
Primary
Concomitant
Somnolence Hospitalization 10/2/2004 50 Male 9/10/2008 Denmark
Primary
Concomitant
Myocardial Infarction Hospitalization 8/1/2005 69 Male 127 lb 9/26/2008 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Hospitalization 8/1/2005 69 Male 127 lb 9/29/2008 Other Health Professional United States
Primary
Concomitant
Rash Hospitalization 10/10/2007 53 Male 10/6/2008 Consumer Denmark
Primary
Secondary
Concomitant
Rash Hospitalization 10/10/2007 53 Male 10/13/2008 Consumer Denmark
Primary
Secondary
Concomitant
Malaise Life Threatening 10/7/2008 79 Female 126 lb 11/14/2008 Consumer United Kingdom
Primary
Concomitant
Swelling Face Other Serious 11/28/2008 Female 12/18/2008 Consumer United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/1/2008 48 Male 205 lb 12/19/2008 Pharmacist United States
Primary
Secondary
Concomitant
Malaise Life Threatening 10/7/2008 79 Female 126 lb 1/29/2009 Consumer United Kingdom
Primary
Concomitant
Increased Tendency To Bruise Other Serious 10/7/2008 79 Female 2/13/2009 United Kingdom
Primary
Concomitant
Rash Pruritic 11/1/2008 47 Female 2/27/2009 Consumer United States
Primary
Concomitant
Vomiting 7/1/2007 Female 238 lb 3/12/2009 Pharmacist United States
Primary
Concomitant
Aplasia Pure Red Cell Hospitalization 3/29/2006 Male 3/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Scar Other Serious 49 Female 150 lb 3/27/2009 United States
Primary
Concomitant
Aplasia Pure Red Cell Hospitalization 3/29/2006 Male 4/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vulvovaginal Candidiasis Hospitalization 1/19/2001 33 Female 295 lb 4/15/2009 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 2/2/2006 Male 5/1/2009 France
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/1998 51 Male 214 lb 5/20/2009 United States
Primary
Concomitant
Petechiae Other Serious 4/27/2009 Male 194 lb 6/3/2009 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 2/2/2006 Male 6/5/2009 France
Primary
Concomitant
Purpura Other Serious 6/7/2009 48 Male 7/6/2009 Germany
Primary
Secondary
Concomitant
Confusional State Other Serious 5/6/2009 71 7/14/2009 Other Health Professional Spain
Primary
Concomitant
Somnolence Other Serious Male 6/29/2009 Consumer United States
Primary
Secondary
Concomitant
Road Traffic Accident Other Serious 5/1/2008 49 Female 7/16/2009 Consumer United States
Primary
Concomitant
Hypoglycaemia Other Serious 4/7/2004 54 Male 251 lb 7/17/2009 United States
Primary
Concomitant
Tremor Other Serious 1/1/2009 Female 181 lb 7/17/2009 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 8/1/2005 69 Male 127 lb 7/24/2009 Other Health Professional United States
Primary
Concomitant
Lacunar Infarction Other Serious 4/1/2009 46 Male 8/7/2009 Other Health Professional United Kingdom
Primary
Concomitant
Confusional State Other Serious 5/6/2009 71 8/25/2009 Other Health Professional Spain
Primary
Concomitant
Convulsion Other Serious Male 9/2/2009 Consumer United States
Primary
Concomitant
Skin Papilloma Female 127 lb 9/18/2009 Consumer United States
Primary
Concomitant
Road Traffic Accident Hospitalization 2/23/2001 59 Male 190 lb 9/23/2009 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 12/16/2003 50 Female 164 lb 9/23/2009 United States
Primary
Concomitant
Sleep Apnoea Syndrome Male 9/24/2009 Physician United States
Primary
Concomitant
Simple Partial Seizures Other Serious 7/23/2009 Male 174 lb 9/30/2009 Consumer Portugal
Primary
Concomitant
International Normalised Ratio Decreased Other Serious 6/1/2009 80 Male 10/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Decreased Other Serious 6/1/2009 80 Male 10/6/2009 United Kingdom
Primary
Concomitant
International Normalised Ratio Decreased Other Serious 6/1/2009 80 Male 10/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
International Normalised Ratio Decreased Other Serious 6/1/2009 80 Male 10/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 8/1/2009 59 Male 183 lb 10/20/2009 Consumer Germany
Primary
Secondary
Vertigo Hospitalization 9/28/2009 Female 10/22/2009 Physician Sweden
Primary
Secondary
Concomitant
International Normalised Ratio Decreased Other Serious 6/1/2009 80 Male 10/16/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 12/8/2009 Female 161 lb 12/11/2009 United States
Primary
Concomitant
Medication Error 11/12/2009 Female 12/21/2009 Consumer
Primary
Concomitant
Oesophagectomy Hospitalization 12/1/2009 Female 12/22/2009 Physician United States
Primary
Concomitant
Rash Erythematous Hospitalization 12/18/2009 83 Male 211 lb 2/3/2010 Consumer United Kingdom
Primary
Concomitant
Rash Erythematous Hospitalization 12/18/2009 83 Male 211 lb 2/5/2010 Other Health Professional United Kingdom
Primary
Concomitant
Swelling Face Hospitalization 1/16/2010 75 Female 102 lb 2/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Ear Pain Other Serious Female 2/15/2010 Pharmacist United Kingdom
Primary
Concomitant
Swelling Face Other Serious 1/16/2010 75 Female 102 lb 2/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swelling Face Other Serious 1/16/2010 75 Female 102 lb 2/18/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stomatitis Hospitalization 11/19/2008 27 Female 471 lb 2/26/2010 Consumer United States
Primary
Concomitant
Troponin Increased 4/13/2009 72 Male 160 lb 4/21/2009 Pharmacist United States
Primary
Concomitant
Swelling Face Hospitalization 1/16/2010 75 Female 102 lb 3/2/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 1/5/2010 Female 140 lb 3/4/2010 Consumer United States
Primary
Secondary
Concomitant
Hypoaesthesia Oral 10/22/2009 49 Female 3/2/2010 Pharmacist United States
Primary
Concomitant
Hypoaesthesia Oral Female 3/2/2010 Pharmacist United States
Primary
Concomitant
Renal Impairment Other Serious 1/1/2005 Male 3/19/2010 Other Health Professional United Kingdom
Primary
Concomitant
Eye Pruritus Female 4/6/2010 Other Health Professional United States
Primary
Concomitant
Drug Level Increased Life Threatening 3/3/2010 40 Male 254 lb 4/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Drug Level Increased Life Threatening 3/3/2010 40 Male 254 lb 5/3/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Suicidal Ideation Hospitalization Male 5/6/2010 Physician United Kingdom
Primary
Concomitant
Fall Other Serious 64 Female 5/3/2010 Other Health Professional United States
Primary
Concomitant
Suicide Attempt Life Threatening 2/1/2010 53 Female 158 lb 2/4/2010 Pharmacist United States
Primary
Concomitant
Complex Partial Seizures Other Serious 4/26/2010 32 Female 5/11/2010 Physician Germany
Primary
Concomitant
Fall Other Serious 64 Female 5/5/2010 United States
Primary
Concomitant
Vomiting Hospitalization 44 Male 95 lb 5/27/2010 Consumer United Kingdom
Primary
Concomitant
Vomiting Hospitalization 6/2/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 44 Male 95 lb 6/3/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 44 Male 95 lb 6/3/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 44 Male 95 lb 6/7/2010 Consumer United Kingdom
Primary
Concomitant
Vomiting Hospitalization 5/11/2010 6/9/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 44 Male 6/10/2010 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 44 Male 95 lb 6/28/2010 Consumer United Kingdom
Primary
Concomitant
Vomiting Hospitalization 44 Male 6/24/2010 United Kingdom
Primary
Concomitant
Nystagmus Other Serious 1/1/2009 66 7/9/2010 Consumer Sweden
Primary
Secondary
Concomitant
Vomiting Hospitalization 44 Male 95 lb 7/12/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 44 Male 95 lb 7/12/2010 Other Health Professional United Kingdom
Primary
Concomitant
Nystagmus Other Serious 11/1/2009 67 Female 7/7/2010 Sweden
Primary
Secondary
Concomitant
Myoclonus Hospitalization 6/18/2010 97 Male 7/15/2010 Physician United Kingdom
Primary
Concomitant
Vomiting 11/1/2007 60 Female 110 lb 7/17/2010 Consumer United States
Primary
Concomitant
Headache 11/13/2007 60 Female 110 lb 7/17/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 44 Male 7/15/2010 United Kingdom
Primary
Concomitant
Myoclonus Hospitalization 6/18/2010 97 Male 7/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Encephalopathy Hospitalization 6/18/2010 97 Male 7/27/2010 Other Health Professional United Kingdom
Primary
Concomitant
Encephalopathy Hospitalization 6/18/2010 97 Male 7/27/2010 Other Health Professional United Kingdom
Primary
Concomitant
Myoclonus Hospitalization 6/18/2010 97 Male 7/27/2010 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 6/16/2010 43 Female 7/28/2010 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 50 Female 120 lb 7/26/2010 Consumer United States
Primary
Secondary
Concomitant
Myoclonus Hospitalization 6/18/2010 97 Male 7/31/2010 United Kingdom
Primary
Concomitant
Myoclonus Hospitalization 6/18/2010 97 Male 8/11/2010 United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 50 Female 120 lb 8/13/2010 Consumer United States
Primary
Secondary
Concomitant
Flushing 8/14/2009 57 Male 200 lb 8/27/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 50 Female 120 lb 9/2/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 6/16/2010 43 Female 9/3/2010 Physician United Kingdom
Primary
Concomitant
Paraparesis Hospitalization 11/4/2009 54 Female 110 lb 9/7/2010 Physician Germany
Primary
Concomitant
Drug Level Increased Life Threatening 3/3/2010 40 Male 254 lb 9/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Paraparesis Hospitalization 11/4/2009 54 Female 110 lb 9/17/2010 Physician Germany
Primary
Concomitant
Post-traumatic Stress Disorder Other Serious 8/1/2010 63 Male 190 lb 9/23/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 50 Female 120 lb 9/23/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 2/19/2010 57 Male 172 lb 9/30/2010 Pharmacist United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 9/13/2010 58 Male 176 lb 10/11/2010 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 9/13/2010 58 Male 176 lb 10/12/2010 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 9/13/2010 58 Male 176 lb 10/12/2010 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 9/13/2010 10/13/2010 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 50 Female 120 lb 10/13/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 50 Female 120 lb 10/15/2010 Consumer United States
Primary
Secondary
Concomitant
Tremor Hospitalization Male 10/15/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/13/2010 58 Male 176 lb 10/15/2010 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 9/13/2010 58 Male 176 lb 10/11/2010 Other Health Professional
Primary
Concomitant
Renal Failure Acute Hospitalization 9/13/2010 58 Male 176 lb 10/15/2010 United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 9/13/2010 58 Male 176 lb 10/19/2010 Other Health Professional
Primary
Concomitant
Renal Failure Acute Other Serious 9/13/2010 58 Male 10/19/2010 Physician
Primary
Concomitant
Renal Failure Acute Hospitalization 9/13/2010 58 Male 176 lb 11/11/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vision Blurred Hospitalization 9/17/2010 72 Male 180 lb 11/2/2010 United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 9/13/2010 58 Male 176 lb 11/15/2010 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 9/13/2010 58 Male 176 lb 11/15/2010 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 9/13/2010 58 Male 11/10/2010 Physician
Primary
Concomitant

Drug Data