Nexium combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rash Vesicular Other Serious 43 Male 2/2/2006 United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Other Serious Female 154 lb 2/13/2006 Physician Ireland
Primary
Concomitant
Interacting
Spleen Disorder Hospitalization 12/21/2005 77 Male 2/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Insomnia 8/1/2005 73 Female 1/5/2006 Consumer United States
Primary
Concomitant
Insomnia 1/1/2005 52 Male 175 lb 1/5/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious Female 154 lb 2/23/2006 Physician Ireland
Primary
Concomitant
Interacting
Pruritus Generalised 9/13/2005 66 Female 222 lb 1/5/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious Female 154 lb 3/16/2006 Physician Ireland
Primary
Concomitant
Interacting
Renal Failure Acute Hospitalization 6/27/2005 76 Female 3/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Portal Hypertensive Gastropathy Hospitalization 1/1/2006 62 Female 3/29/2006 Consumer Denmark
Primary
Concomitant
Vomiting Hospitalization 12/23/2005 86 Female 4/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vascular Access Complication Hospitalization 9/1/2005 Male 175 lb 4/26/2006 Consumer United States
Primary
Concomitant
Macular Degeneration Other Serious 3/1/2006 Male 209 lb 5/8/2006 Physician Denmark
Primary
Concomitant
Middle Insomnia 11/1/2005 76 Male 230 lb 4/3/2006 Consumer United States
Primary
Concomitant
Sunburn Other Serious 1/10/2006 69 Male 248 lb 2/21/2006 Physician United States
Primary
Concomitant
Ulcer Other Serious 12/5/2005 73 Male 194 lb 12/6/2005 Other Health Professional United States
Primary
Concomitant
Intentional Drug Misuse Other Serious 71 Male 238 lb 4/20/2006 United States
Primary
Concomitant
Tooth Extraction Other Serious 3/1/2006 71 Female 114 lb 6/22/2006 Other Health Professional United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2001 Female 111 lb 6/29/2006 Physician United States
Primary
Concomitant
Rash Death 5/1/2006 83 Male 176 lb 6/29/2006 Physician South Africa
Primary
Secondary
Rash Death 5/1/2006 83 Male 7/5/2006 Physician South Africa
Primary
Secondary
Orthostatic Hypotension 6/1/2003 75 Male 5/24/2006 Consumer United States
Primary
Concomitant
Viral Infection Other Serious 6/16/2006 66 Male 7/12/2006 Physician Australia
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/16/2006 66 Male 7/19/2006 Physician Australia
Primary
Secondary
Concomitant
Dizziness 3/1/2006 85 Male 175 lb 7/12/2006 Consumer United States
Primary
Concomitant
Nausea 4/25/2006 69 Female 200 lb 7/12/2006 Consumer United States
Primary
Concomitant
Dysgeusia 79 Female 135 lb 5/24/2006 Consumer United States
Primary
Concomitant
Skin Fissures Disability 1/1/2006 49 Female 8/3/2006 Physician United States
Primary
Concomitant
Somnolence 2/1/2006 65 Male 7/12/2006 Consumer United States
Primary
Concomitant
Gastritis Hospitalization 2/25/2006 Female 154 lb 8/21/2006 Physician Denmark
Primary
Secondary
Concomitant
Stress Death 74 Male 8/23/2006 Physician Ireland
Primary
Concomitant
Tooth Extraction Other Serious 1/12/2006 71 Female 114 lb 9/9/2006 Other Health Professional United States
Primary
Concomitant
Knee Arthroplasty Hospitalization 8/24/2006 76 Female 9/1/2006 Pharmacist United States
Primary
Concomitant
Stress Death 74 Male 9/18/2006 Physician Ireland
Primary
Concomitant
Pneumonia Hospitalization 1/1/2006 71 Male 9/13/2006 Physician Norway
Primary
Concomitant
Pneumonia Hospitalization 1/1/2006 71 Male 9/21/2006 Physician Norway
Primary
Concomitant
Serotonin Syndrome Other Serious 9/23/2006 38 Female 225 lb 9/28/2006 Pharmacist United States
Primary
Concomitant
Upper Limb Fracture Required Intervention 9/13/2006 62 Female 214 lb 9/28/2006 Physician Germany
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 10/25/2004 73 Male 250 lb 10/18/2006 United States
Primary
Concomitant
Serotonin Syndrome Other Serious 9/23/2006 38 Female 11/3/2006 Physician United States
Primary
Concomitant
Peritonitis Other Serious Male 11/2/2006 Denmark
Primary
Concomitant
Spinal Osteoarthritis Other Serious 4/1/2005 70 Male 245 lb 11/6/2006 Physician United States
Primary
Concomitant
Vomiting Required Intervention 9/13/2006 62 Female 214 lb 10/31/2006 Physician Germany
Primary
Concomitant
Rectal Haemorrhage Hospitalization 10/17/2006 66 Male 134 lb 11/14/2006 Physician France
Primary
Concomitant
Wheezing Hospitalization 9/15/2006 65 Male 256 lb 12/1/2006 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 8/27/2006 65 Male 256 lb 12/1/2006 Physician United States
Primary
Concomitant
Stent Placement Death 5/1/2006 83 Male 176 lb 12/4/2006 Physician South Africa
Primary
Secondary
Staphylococcal Infection Other Serious 9/23/2006 38 Female 219 lb 11/30/2006 Physician United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Disability 7/24/2006 43 Male 148 lb 12/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 1/1/2006 70 Male 198 lb 12/13/2006 Physician Germany
Primary
Concomitant
Cholestasis Hospitalization 10/2/2006 Female 12/27/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Tooth Loss Other Serious 1/14/2007 87 Female 138 lb 1/19/2007 United States
Primary
Concomitant
Vomiting Other Serious 10/25/2006 56 Female 132 lb 1/22/2007 Physician Germany
Primary
Concomitant
Weight Increased Other Serious 11/1/2003 Female 10/10/2006 Consumer United States
Primary
Concomitant
Death Death 1/1/2007 Male 192 lb 1/31/2007 Australia
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 9/15/2006 65 Male 256 lb 2/1/2007 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 8/27/2006 65 Male 256 lb 2/1/2007 Physician United States
Primary
Concomitant
Necrosis Other Serious 2/1/2006 83 Male 375 lb 2/1/2007 Germany
Primary
Concomitant
Subdural Haematoma Death 1/8/2007 60 Male 119 lb 2/6/2007 Other Health Professional France
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 1/3/2007 Female 148 lb 2/6/2007 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/21/2007 Male 230 lb 2/9/2007 Consumer United States
Primary
Concomitant
Rhabdomyolysis Other Serious 57 Male 2/28/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 5/1/2006 77 Male 3/2/2007 Physician Germany
Primary
Concomitant
Rash Disability 1/1/2006 49 Female 3/1/2007 Physician United States
Primary
Concomitant
Rhabdomyolysis Other Serious 9/14/2006 51 Male 272 lb 3/6/2007 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 12/9/2006 74 Male 3/15/2007 Consumer France
Primary
Secondary
Concomitant
Death Death 1/1/2007 Male 192 lb 3/16/2007 Australia
Primary
Concomitant
Death Death 64 Female 3/12/2007 Physician Sweden
Primary
Concomitant
Type Ii Hypersensitivity Hospitalization 2/13/2007 77 Female 3/12/2007 Physician Switzerland
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 12/9/2006 75 Male 3/21/2007 Other Health Professional France
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2003 46 Male 145 lb 3/22/2007 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 12/9/2006 75 Male 3/26/2007 Other Health Professional France
Primary
Secondary
Concomitant
Death Death 1/1/2007 Male 192 lb 3/30/2007 Australia
Primary
Concomitant
Rhabdomyolysis Hospitalization 1/1/2006 72 Female 3/31/2007 Physician Denmark
Primary
Secondary
Concomitant
Sluggishness 9/7/2006 Male 289 lb 1/12/2007 Consumer United States
Primary
Concomitant
Asthma 1/1/2005 53 Female 249 lb 1/23/2007 Other Health Professional United States
Primary
Concomitant
Insomnia 7/1/2006 77 Male 180 lb 1/12/2007 Consumer United States
Primary
Concomitant
Urticaria Generalised Hospitalization 8/1/2006 71 Female 4/6/2007 Other Health Professional France
Primary
Secondary
Concomitant
Death Death Female 4/9/2007 Physician Sweden
Primary
Concomitant
Rhabdomyolysis Hospitalization 6/9/2006 72 Female 3/31/2007 Physician Denmark
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 11/1/2006 72 Male 185 lb 4/12/2007 Consumer Norway
Primary
Concomitant
Weight Decreased Hospitalization 12/9/2006 75 Male 4/22/2007 Physician France
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 3/1/2007 78 Female 4/21/2007 United States
Primary
Concomitant
Weight Decreased Hospitalization 12/9/2006 74 Male 4/23/2007 Consumer France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/1/2006 63 Female 180 lb 4/24/2007 Consumer United States
Primary
Concomitant
Toothache 75 Male 185 lb 4/30/2007 United States
Primary
Concomitant
Toxic Epidermal Necrolysis Death 8/16/2006 71 Female 4/30/2007 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/1/2005 49 Female 160 lb 1/18/2007 Physician United States
Primary
Concomitant
Tachycardia Hospitalization 4/1/2007 78 Male 5/3/2007 Physician Germany
Primary
Concomitant
Death Death 1/1/2007 Male 192 lb 5/4/2007 Australia
Primary
Concomitant
Urticaria Generalised Hospitalization 9/30/2005 71 Female 5/4/2007 Other Health Professional France
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 8/16/2006 71 Female 5/8/2007 Other Health Professional France
Primary
Secondary
Concomitant
Urticaria Generalised Hospitalization 8/15/2006 71 Female 5/14/2007 Other Health Professional France
Primary
Secondary
Concomitant
Necrosis Other Serious 2/1/2006 83 Male 375 lb 5/15/2007 Germany
Primary
Concomitant
Heart Rate Irregular Other Serious 4/1/2007 Male 5/16/2007 Physician United States
Primary
Concomitant
Thyroiditis Hospitalization 2/28/2007 Male 5/24/2007 Other Health Professional France
Primary
Concomitant
Visual Disturbance Other Serious Female 5/26/2007 United States
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 12/1/2002 75 Male 201 lb 5/25/2007 Physician United States
Primary
Concomitant
Oedema Peripheral Hospitalization 2/1/2007 84 Female 5/30/2007 Physician United States
Primary
Concomitant
Dysgeusia 1/25/2007 70 Female 168 lb 4/12/2007 Consumer United States
Primary
Concomitant
Hepatic Enzyme Increased 12/12/2006 70 Female 5/17/2007 United States
Primary
Concomitant
Unevaluable Event Other Serious 1/1/2007 Male 184 lb 6/13/2007 Consumer United States
Primary
Concomitant
Fall Hospitalization 11/11/2006 76 Female 6/19/2007 Other Health Professional France
Primary
Concomitant
Interacting
Rhabdomyolysis Other Serious 3/6/2007 48 Male 179 lb 6/20/2007 Germany
Primary
Secondary
Traumatic Haematoma Death 11/1/2005 Female 6/27/2007 Physician Norway
Primary
Secondary
Concomitant
Vomiting Other Serious 6/1/2007 Female 150 lb 6/29/2007 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization 1/1/2003 55 Female 7/5/2007 Physician France
Primary
Secondary
Concomitant
Rash Generalised 5/4/2007 61 Male 7/6/2007 Consumer United States
Primary
Concomitant
Peritoneal Haematoma Death 11/1/2005 Female 7/10/2007 Physician Norway
Primary
Secondary
Concomitant
Hypoacusis Other Serious 80 Female 141 lb 7/12/2007 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious 1/1/2007 84 Female 169 lb 7/14/2007 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 7/8/2004 Male 7/25/2007 Physician Switzerland
Primary
Secondary
Concomitant
Hypoacusis Other Serious 80 Female 141 lb 7/27/2007 Consumer United States
Primary
Concomitant
Staphylococcal Sepsis Other Serious 2/1/2006 83 Male 375 lb 7/31/2007 Germany
Primary
Concomitant
Vision Blurred Other Serious 7/8/2004 Male 7/31/2007 Physician Switzerland
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/24/2007 63 Male 7/25/2007 Norway
Primary
Concomitant
Urobilin Urine Present Hospitalization 6/24/2007 63 Male 8/6/2007 Other Health Professional Norway
Primary
Concomitant
Urine Colour Abnormal Other Serious 5/15/2007 78 Male 8/6/2007 Physician United States
Primary
Secondary
Concomitant
Death Death 1/1/2007 Male 192 lb 8/22/2007 Australia
Primary
Concomitant
Retroperitoneal Haemorrhage Hospitalization 3/23/2006 73 Female 8/27/2007 Other Health Professional Australia
Primary
Secondary
Pemphigoid Hospitalization 5/26/2007 81 Male 9/4/2007 Physician Sweden
Primary
Concomitant
Hyponatraemia Hospitalization 1/4/2006 82 Female 9/4/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 12/9/2006 75 Male 9/14/2007 Physician France
Primary
Secondary
Concomitant
Somnolence Other Serious 7/1/2007 Female 249 lb 9/17/2007 Physician Germany
Primary
Concomitant
Hepatic Steatosis 12/1/2006 70 Female 8/16/2007 Other Health Professional United States
Primary
Concomitant
Hypoacusis Other Serious 80 Female 141 lb 9/26/2007 Consumer United States
Primary
Concomitant
Pelvic Pain 7/27/2007 63 Female 159 lb 9/26/2007 Consumer United States
Primary
Concomitant
Speech Disorder Hospitalization 3/27/2006 68 Male 150 lb 9/27/2007
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 3/27/2006 68 Male 150 lb 9/28/2007
Primary
Secondary
Concomitant
Optic Neuritis Other Serious 7/8/2004 Male 9/28/2007 Physician Switzerland
Primary
Secondary
Concomitant
Renal Failure Hospitalization 70 Female 84 lb 9/25/2007 Consumer Germany
Primary
Secondary
Concomitant
Gastric Haemorrhage Other Serious Female 9/25/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 3/27/2006 68 Male 150 lb 10/1/2007
Primary
Secondary
Concomitant
Urine Colour Abnormal Other Serious 5/15/2007 78 Male 8/6/2007 Physician United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 12/1/2002 75 Male 201 lb 10/8/2007 Physician United States
Primary
Concomitant
Haematoma Other Serious 67 Male 10/9/2007 Physician Germany
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 1/1/2007 Female 199 lb 10/10/2007 Consumer United States
Primary
Concomitant
Tachycardia Other Serious 6/16/2006 66 Male 10/8/2007 Physician Australia
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 79 Male 10/17/2007 Physician Switzerland
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 149 lb 10/24/2007 Consumer United States
Primary
Concomitant
Oral Pain 71 Female 10/24/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 9/1/2007 56 Male 10/25/2007 Other Health Professional United States
Primary
Concomitant
Haematoma Other Serious 67 Male 10/30/2007 Physician Germany
Primary
Secondary
Concomitant
Serotonin Syndrome Required Intervention 7/23/2007 60 Female 183 lb 10/28/2007 Other Health Professional United States
Primary
Concomitant
Rash Other Serious 1/1/2007 73 Female 122 lb 11/2/2007 Consumer United States
Primary
Concomitant
Urinary Bladder Haemorrhage Hospitalization 5/23/2007 48 Female 10/31/2007 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2007 Female 160 lb 11/7/2007 Consumer United States
Primary
Concomitant
Blood Glucose Increased 46 Male 11/14/2007 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 11/8/2007 66 Female 174 lb 11/14/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Life Threatening 9/1/2007 58 Male 171 lb 11/16/2007 Other Health Professional United States
Primary
Concomitant

Drug Data