Levofloxacin combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Increased Hospitalization 10/14/2004 46 Male 188 lb 1/12/2006 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Hospitalization 11/6/2005 53 Male 12/27/2005 Consumer United States
Primary
Concomitant
Hypophosphataemia Life Threatening 8/31/2005 61 Female 4/20/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypophosphataemia Life Threatening 8/31/2005 61 Female 5/1/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 3/23/2006 Male 154 lb 6/23/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 5/15/2006 69 Female 6/22/2006 Physician Hong Kong
Primary
Concomitant
Weight Increased Hospitalization 4/13/2006 67 Male 6/29/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 5/15/2006 69 Female 7/14/2006 Physician Hong Kong
Primary
Concomitant
Clostridium Difficile Colitis Hospitalization 7/15/2006 57 Female 212 lb 7/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 3/29/2006 66 Female 9/26/2006 Pharmacist United States
Primary
Secondary
Clostridial Infection Hospitalization 10/11/2006 83 Male 158 lb 10/13/2006 Pharmacist United States
Primary
Concomitant
Viral Infection Hospitalization 10/10/2006 70 Female 11/6/2006 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Required Intervention 9/1/2006 60 Female 182 lb 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Pneumonia Aspiration Death 2/26/2003 Male 230 lb 2/6/2007 Pharmacist United States
Primary
Concomitant
Interacting
Electrocardiogram Qt Prolonged Other Serious 11/6/2006 55 Male 164 lb 1/15/2007 Pharmacist United States
Primary
Concomitant
Hypophosphataemia Life Threatening 8/31/2005 61 Female 3/16/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Tendon Rupture Hospitalization 3/18/2007 84 Male 5/8/2007 United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/15/2006 71 Female 154 lb 1/14/2007 Pharmacist United States
Primary
Concomitant
Megakaryocytes Increased 3/27/2007 63 Male 196 lb 5/29/2007 Pharmacist United States
Primary
Concomitant
Unevaluable Event Other Serious 1/1/2007 Male 184 lb 6/13/2007 Consumer United States
Primary
Concomitant
Malaise Other Serious 3/22/2007 75 Female 6/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hypophosphataemia Life Threatening 8/31/2005 61 Female 6/27/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 6/1/2007 Male 163 lb 7/10/2007 United States
Primary
Concomitant
Throat Tightness Other Serious 6/5/2007 84 Female 8/31/2007 Physician United States
Primary
Concomitant
White Blood Cells Urine Positive Hospitalization 6/1/2007 Female 219 lb 10/5/2007 Physician United States
Primary
Secondary
Concomitant
Nodal Marginal Zone B-cell Lymphoma Other Serious 10/15/2007 Female 152 lb 11/7/2007 United States
Primary
Concomitant
Troponin I Increased Other Serious 6/19/2007 45 Male 11/9/2007 Physician China
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/14/2004 46 Male 188 lb 11/20/2007 Physician Germany
Primary
Secondary
Concomitant
Chest Pain Hospitalization 9/27/2007 Male 12/6/2007 Pharmacist United States
Primary
Concomitant
Pulmonary Embolism Other Serious 8/24/2007 67 Female 1/9/2008 Other Health Professional United States
Primary
Concomitant
Upper Respiratory Tract Infection Death 2/3/2008 69 Male 2/4/2008 Other Health Professional United States
Primary
Concomitant
Hypophosphataemia Life Threatening 8/31/2005 61 Female 3/18/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 1/17/2007 Female 182 lb 4/10/2008 United States
Primary
Concomitant
Pyrexia Hospitalization 4/6/2008 77 Male 4/23/2008 Japan
Primary
Concomitant
Nodal Marginal Zone B-cell Lymphoma Other Serious 10/15/2007 Female 152 lb 5/2/2008 United States
Primary
Concomitant
Pyrexia Hospitalization 4/6/2008 77 Male 6/1/2008 Japan
Primary
Concomitant
Thrombophlebitis Superficial Hospitalization 8/11/2008 74 Female 145 lb 9/22/2008 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 4/14/2008 Female 250 lb 10/1/2008 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 4/14/2008 Female 250 lb 11/6/2008 Physician United States
Primary
Concomitant
Respiratory Failure Life Threatening 6/24/2008 Female 163 lb 6/29/2008 Pharmacist United States
Primary
Concomitant
Pneumonia Hospitalization 4/14/2008 Female 250 lb 11/24/2008 Physician United States
Primary
Concomitant
Pulmonary Haemorrhage Other Serious 7/25/2007 69 Male 11/28/2008 China
Primary
Concomitant
Pneumonia Hospitalization 4/14/2008 Female 250 lb 12/18/2008 Physician United States
Primary
Concomitant
Panic Attack Other Serious Male 12/22/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Troponin Increased Other Serious 1/1/2003 78 Male 140 lb 1/8/2009 United States
Primary
Concomitant
Pneumonia Cryptococcal Hospitalization 11/22/2008 Male 220 lb 2/9/2009 United States
Primary
Secondary
Concomitant
Injection Site Pruritus Other Serious 7/17/2008 76 Female 155 lb 2/15/2009 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 7/1/2008 Male 207 lb 3/9/2009 Pharmacist
Primary
Concomitant
Troponin Increased Other Serious 1/1/2003 78 Male 140 lb 4/14/2009 United States
Primary
Concomitant
Pain In Extremity Other Serious 59 Male 5/28/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Toxicity Other Serious 62 Male 5/29/2009
Primary
Secondary
Concomitant
Shock Haemorrhagic Life Threatening 1/13/2004 Female 196 lb 6/23/2009 Physician Israel
Primary
Secondary
Concomitant
Pyrexia Life Threatening 7/29/2004 Male 218 lb 6/23/2009 Physician Israel
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 10/14/2004 Male 188 lb 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Urinary Retention Other Serious 10/14/2004 Male 7/2/2009 Physician Germany
Primary
Secondary
Concomitant
Agranulocytosis Life Threatening 5/24/2009 76 Male 198 lb 7/10/2009 Pharmacist United States
Primary
Concomitant
Panic Attack Other Serious Male 7/24/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Shock Haemorrhagic Life Threatening 1/13/2004 50 Female 7/31/2009 Physician Israel
Primary
Secondary
Concomitant
Panic Attack Other Serious Male 8/11/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Haemoptysis Death Male 163 lb 8/27/2009 Consumer Brazil
Primary
Concomitant
Respiratory Rate Increased Disability 8/26/2009 78 Female 96 lb 8/27/2009 Pharmacist United States
Primary
Concomitant
Febrile Neutropenia Other Serious 8/31/2009 54 Female 110 lb 9/8/2009 Physician United States
Primary
Secondary
Concomitant
Ovarian Cancer Death 10/10/2008 64 Female 9/10/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 8/31/2009 54 Female 110 lb 9/11/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/20/2009 77 Male 165 lb 9/28/2009 Physician United States
Primary
Secondary
Concomitant
Somnambulism Other Serious 10/3/2009 53 Male 160 lb 10/7/2009 Pharmacist United States
Primary
Concomitant
Tubulointerstitial Nephritis Hospitalization 67 Male 10/16/2009 Other Health Professional Spain
Primary
Concomitant
Blood Pressure Increased Hospitalization 10/1/2009 67 Male 11/13/2009 Consumer United Kingdom
Primary
Concomitant
Pancreatic Necrosis Hospitalization 12/1/2008 63 Female 11/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anaphylactic Reaction Other Serious 72 Female 12/1/2009 Physician United States
Primary
Concomitant
Renal Failure Other Serious 2/13/2007 61 Male 214 lb 12/9/2009 Lawyer United States
Primary
Secondary
Concomitant
Stress Other Serious 10/11/2007 56 Female 98 lb 12/31/2009 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Other Serious 10/11/2007 56 Female 98 lb 1/20/2010 Physician Japan
Primary
Secondary
Concomitant
Vasculitis Other Serious 1/31/2010 66 Male 325 lb 2/8/2010 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/20/2009 77 Male 165 lb 2/11/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 10/1/2007 61 Male 214 lb 3/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tendonitis Other Serious 1/1/2010 66 Male 3/9/2010 Other Health Professional Japan
Primary
Concomitant
Weight Decreased Other Serious 10/24/2006 Male 3/12/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 10/24/2006 Male 3/24/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 10/24/2006 81 Male 4/11/2010 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2007 69 Female 4/19/2010 United States
Primary
Secondary
Concomitant
Vascular Insufficiency Other Serious 1/1/1995 57 Male 5/11/2010 United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 6/7/2010 Other Health Professional Israel
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization Female 6/10/2010 Other Health Professional Israel
Primary
Secondary
Weight Increased Other Serious 1/1/1995 57 Male 6/15/2010 United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization Female 6/16/2010 Physician France
Primary
Secondary
Thrombocytopenia Hospitalization 70 Female 6/18/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization Female 6/21/2010 Physician France
Primary
Secondary
Toxic Epidermal Necrolysis Hospitalization 70 Female 6/22/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 6/22/2010 Other Health Professional France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 70 Female 6/23/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 6/29/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Depression 36 Female 6/29/2010 Consumer United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 6/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 7/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 1/1/2007 69 Female 148 lb 7/1/2010 Lawyer United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 10/16/2009 67 Male 168 lb 7/6/2010 Physician Canada
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization Female 7/7/2010 Other Health Professional Israel
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 7/7/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/24/2006 81 Male 7/7/2010 United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 7/9/2010 Physician United Kingdom
Primary
Secondary
Toxic Epidermal Necrolysis Hospitalization 70 Female 7/9/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 7/9/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/12/2010 Physician Israel
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 7/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Required Intervention 70 Female 7/2/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 7/13/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization Female 7/13/2010 Other Health Professional Israel
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 7/6/2010 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 7/8/2010 United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/21/2010 69 Female 139 lb 7/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 7/18/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 7/19/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/20/2010 Physician Israel
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 7/19/2010 United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 70 Female 7/13/2010 Israel
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 7/14/2010 Other Health Professional Denmark
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 7/21/2010 Other Health Professional Israel
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 7/21/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/4/2007 69 Female 326 lb 7/19/2010 Lawyer United States
Primary
Secondary
Concomitant
Drug Interaction Other Serious 12/30/2009 84 Female 159 lb 7/26/2010 Pharmacist Germany
Primary
Concomitant
Interacting
Drug Interaction Hospitalization 12/30/2009 84 Female 159 lb 7/28/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Drug Interaction Hospitalization 12/30/2009 84 Female 159 lb 7/26/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Drug Interaction Hospitalization 12/30/2009 84 Female 8/4/2010 Other Health Professional Japan
Primary
Concomitant
Interacting
Weight Increased Other Serious 1/1/1995 57 Male 8/6/2010 United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 12/1/2009 84 Female 159 lb 8/9/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Thrombocytopenia Other Serious 6/9/2010 69 Female 139 lb 8/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Interaction Other Serious 12/30/2009 84 Female 159 lb 8/13/2010 Pharmacist Germany
Primary
Concomitant
Interacting
Drug Interaction Hospitalization 12/30/2009 84 Female 159 lb 8/17/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Thrombocytopenia Other Serious 6/9/2010 69 Female 139 lb 8/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/7/2006 81 Male 8/23/2010 United States
Primary
Concomitant
Drug Interaction Hospitalization 12/30/2009 84 Female 8/31/2010 Other Health Professional Japan
Primary
Concomitant
Interacting
Loss Of Consciousness Life Threatening 3/29/2010 71 Male 9/8/2010 Other Health Professional Japan
Primary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 9/17/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 8/31/2008 75 Female 9/17/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 5/15/2010 59 Male 209 lb 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 11/29/2008 69 Male 11/16/2010 Physician Germany
Primary
Secondary
Concomitant
Hepatitis Acute Other Serious 77 Male 128 lb 11/22/2010 Other Health Professional Portugal
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 1/31/2010 66 Male 325 lb 10/28/2010 Pharmacist
Primary
Concomitant
Pneumonia Hospitalization 12/8/2010 61 Female 182 lb 12/17/2010 Consumer United States
Primary
Secondary
Concomitant
Drug Screen Negative Hospitalization 12/1/2010 92 Male 1/5/2011 Pharmacist United States
Primary
Concomitant
Syncope Hospitalization 1/13/2011 65 Male 132 lb 1/19/2011 Physician Germany
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 1/22/2011 55 Female 134 lb 2/7/2011 Physician United States
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 1/22/2011 55 Female 134 lb 2/10/2011 Consumer United States
Primary
Secondary
Concomitant
Tendonitis Other Serious 1/11/2011 57 Male 139 lb 2/9/2011 Pharmacist United States
Primary
Concomitant
Pericardial Effusion Hospitalization 1/22/2011 55 Female 134 lb 2/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 1/22/2011 55 Female 134 lb 3/1/2011 Consumer United States
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 1/22/2011 55 Female 134 lb 3/4/2011 Physician United States
Primary
Secondary
Concomitant
Cystitis Other Serious 6/9/2010 69 Female 139 lb 3/9/2011 Consumer United States
Primary
Secondary
Concomitant
Cerebral Ischaemia Hospitalization 1/1/2007 68 Male 3/3/2011 Physician United States
Primary
Concomitant

Drug Data