Celebrex combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Oesophageal Carcinoma Death Male 195 lb 1/3/2006 Physician United States
Primary
Concomitant
Iron Deficiency Anaemia Other Serious 9/21/2005 83 Male 207 lb 1/24/2006 Consumer United Kingdom
Primary
Concomitant
Hypersensitivity 9/1/2005 50 Female 1/5/2006 Physician United States
Primary
Concomitant
Dehydration Other Serious Male 209 lb 2/1/2006 Physician New Zealand
Primary
Secondary
Concomitant
Nitritoid Crisis Life Threatening 10/18/2004 74 Male 2/20/2006 United Kingdom
Primary
Concomitant
Interacting
Pneumonia Hospitalization 1/1/2004 84 Male 130 lb 4/11/2005 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 6/8/2005 76 Female 3/1/2006 Physician Norway
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2004 53 Female 3/10/2006 Other Health Professional Norway
Primary
Concomitant
Drug Interaction Other Serious Male 209 lb 3/27/2006 Physician New Zealand
Primary
Secondary
Concomitant
Hypernatraemia Other Serious 1/1/2006 69 Male 196 lb 4/19/2006 Physician France
Primary
Concomitant
Myocardial Infarction Death 87 Male 5/3/2006 Pharmacist Canada
Primary
Concomitant
Myocardial Infarction Death 87 Male 5/3/2006 Pharmacist Canada
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 69 Female 196 lb 5/1/2006 Physician France
Primary
Concomitant
Myocardial Infarction Death 87 Male 5/5/2006 Consumer Canada
Primary
Concomitant
Myocardial Infarction Death 87 Male 5/5/2006 Consumer Canada
Primary
Concomitant
Somnolence 1/1/2006 70 Female 158 lb 4/3/2006 Consumer United States
Primary
Concomitant
Middle Insomnia 11/1/2005 76 Male 230 lb 4/3/2006 Consumer United States
Primary
Concomitant
Insomnia 3/3/2006 82 Male 180 lb 4/3/2006 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 51 Male 215 lb 6/7/2006 United States
Primary
Secondary
Concomitant
Angioneurotic Oedema Life Threatening 6/9/2006 72 Female 144 lb 6/14/2006 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Hospitalization 5/28/2006 68 Male 198 lb 7/26/2006 United Kingdom
Primary
Secondary
Concomitant
Erythema Multiforme Hospitalization 5/6/2006 74 Male 8/10/2006 Other Health Professional France
Primary
Secondary
Concomitant
Peptic Ulcer Haemorrhage Other Serious 1/1/2005 Male 155 lb 7/5/2006 Physician United States
Primary
Secondary
Concomitant
Trigeminal Neuralgia Hospitalization 1/1/2005 52 Female 220 lb 8/11/2006 Physician Germany
Primary
Secondary
Concomitant
Lymphangioma Other Serious 1/1/2006 Female 8/18/2006 Physician Germany
Primary
Concomitant
Stomach Discomfort Other Serious 1/1/2004 62 Male 250 lb 9/11/2006 United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 51 Male 215 lb 9/13/2006 United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 51 Male 215 lb 9/22/2006 United States
Primary
Secondary
Concomitant
Rash Hospitalization 5/6/2006 74 Male 10/5/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2003 54 Female 10/31/2006 Norway
Primary
Secondary
Concomitant
Intervertebral Disc Protrusion Other Serious Female 143 lb 11/13/2006 United States
Primary
Concomitant
Skin Exfoliation Other Serious 10/1/2006 Female 11/16/2006 Brazil
Primary
Concomitant
Asthenia Other Serious 1/1/2006 73 Female 12/8/2006 Physician Portugal
Primary
Secondary
Trismus Other Serious 12/1/2005 35 Female 165 lb 12/13/2006 Physician Germany
Primary
Concomitant
Drug Ineffective Hospitalization 1/3/2007 Female 148 lb 2/6/2007 Consumer United States
Primary
Secondary
Concomitant
Cardiac Arrest Hospitalization 3/20/2007 74 Male 4/3/2007 Other Health Professional United States
Primary
Concomitant
Insomnia 10/1/2006 79 Male 187 lb 1/12/2007 Consumer United States
Primary
Concomitant
Dysgeusia 11/4/2006 76 Female 260 lb 1/12/2007 Consumer United States
Primary
Concomitant
Nervousness Other Serious 1/27/2003 Male 164 lb 4/6/2007 Lawyer United States
Primary
Concomitant
Melaena Hospitalization 80 Male 4/6/2007 Physician France
Primary
Concomitant
Interacting
Melaena Hospitalization 80 Male 4/16/2007 Physician France
Primary
Secondary
Concomitant
Interacting
Pyrexia Other Serious 4/13/2007 73 Male 5/7/2007 Physician Germany
Primary
Concomitant
Melaena Other Serious 3/16/2007 Male 187 lb 5/9/2007 Physician France
Primary
Concomitant
Interacting
Pyrexia Other Serious 4/13/2007 73 Male 5/10/2007 Physician Germany
Primary
Concomitant
Pyrexia Other Serious 4/13/2007 73 Male 5/17/2007 Physician Germany
Primary
Concomitant
Lymphangioma Other Serious 12/1/2005 Female 165 lb 5/18/2007 Physician Germany
Primary
Concomitant
Pyrexia Other Serious 4/13/2007 73 Male 5/22/2007 Physician Germany
Primary
Concomitant
Pyrexia Other Serious 4/13/2007 73 Male 5/24/2007 Physician Germany
Primary
Concomitant
Cardiac Arrest Hospitalization 3/20/2007 74 Male 7/9/2007 Other Health Professional United States
Primary
Concomitant
Diarrhoea Other Serious 5/1/2007 Male 238 lb 7/20/2007 Physician United States
Primary
Concomitant
Urine Colour Abnormal Other Serious 5/15/2007 78 Male 8/6/2007 Physician United States
Primary
Secondary
Concomitant
Drug Effect Decreased 6/1/2007 85 Male 165 lb 7/10/2007 Consumer United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 Female 181 lb 9/10/2007 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective 3/5/2007 79 Male 7/5/2007 Consumer United States
Primary
Concomitant
Urine Colour Abnormal Other Serious 5/15/2007 78 Male 8/6/2007 Physician United States
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 3/1/2007 66 Female 10/17/2007 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2007 Female 160 lb 11/7/2007 Consumer United States
Primary
Concomitant
Spinal Laminectomy Other Serious 1/1/1999 Male 180 lb 11/14/2007 Consumer United States
Primary
Concomitant
Chest Pain Hospitalization 9/27/2007 Male 12/6/2007 Pharmacist United States
Primary
Concomitant
Hospitalisation Hospitalization 1/1/2008 74 Female 1/22/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 10/1/2007 Male 244 lb 2/22/2008 Consumer United States
Primary
Secondary
Concomitant
Epistaxis 1/28/2007 73 Male 194 lb 2/1/2007 Consumer United States
Primary
Secondary
Concomitant
Scar 63 Male 204 lb 3/12/2008 United States
Primary
Concomitant
Type I Hypersensitivity Hospitalization 1/22/2008 68 Female 154 lb 4/4/2008 Physician Switzerland
Primary
Concomitant
Palpitations Other Serious 12/1/2007 Female 297 lb 4/7/2008 United States
Primary
Concomitant
Thinking Abnormal Disability 2/4/2008 Female 126 lb 4/7/2008 Consumer United States
Primary
Concomitant
Dysphonia 80 Female 160 lb 4/29/2008 Consumer United States
Primary
Concomitant
Hypertension Hospitalization 10/24/2007 Female 154 lb 5/15/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Macular Degeneration Other Serious Female 6/9/2008 Consumer United States
Primary
Concomitant
Reproductive Tract Disorder Other Serious 51 Female 6/12/2008 Physician United States
Primary
Secondary
Weight Decreased 12/1/2007 60 Male 295 lb 4/10/2008 Consumer United States
Primary
Concomitant
Viral Pharyngitis 5/1/2008 Female 7/22/2008 Consumer United States
Primary
Concomitant
Sinusitis 8/1/2007 64 Female 219 lb 4/10/2008 Consumer United States
Primary
Concomitant
Mental Impairment Other Serious 7/1/2008 Male 271 lb 7/31/2008 United States
Primary
Concomitant
Surgery Other Serious 1/1/2008 74 Female 181 lb 8/19/2008 Pharmacist Australia
Primary
Concomitant
Hypertension Other Serious Male 196 lb 8/22/2008 Consumer United States
Primary
Concomitant
Palpitations Other Serious 1/1/2008 63 Female 297 lb 8/22/2008 United States
Primary
Concomitant
No Adverse Event 7/1/2008 Male 271 lb 9/22/2008 United States
Primary
Concomitant
Oesophageal Pain Other Serious Female 161 lb 9/23/2008 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 4/14/2008 Female 250 lb 10/1/2008 Physician United States
Primary
Concomitant
Hot Flush Other Serious 1/1/2008 Female 10/9/2008 Consumer United States
Primary
Concomitant
Oesophageal Pain Other Serious Female 161 lb 10/27/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 9/18/2008 Female 200 lb 11/3/2008 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2008 Female 174 lb 11/5/2008 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 4/14/2008 Female 250 lb 11/6/2008 Physician United States
Primary
Concomitant
Myalgia 8/22/2008 75 Female 87 lb 10/20/2008 Other Health Professional United States
Primary
Concomitant
Fluid Retention Other Serious 7/1/2008 80 Male 190 lb 11/21/2008 Pharmacist United States
Primary
Concomitant
Pneumonia Hospitalization 4/14/2008 Female 250 lb 11/24/2008 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2008 Female 174 lb 12/11/2008 Consumer United States
Primary
Concomitant
Swollen Tongue Other Serious 12/1/2008 Female 12/16/2008 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/14/2008 Female 250 lb 12/18/2008 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2008 Female 174 lb 12/24/2008 Consumer United States
Primary
Concomitant
Rectal Neoplasm Other Serious 9/25/2007 Female 12/30/2008 Belgium
Primary
Secondary
Concomitant
Cervical Dysplasia Hospitalization 5/6/2008 Female 1/7/2009 Belgium
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2008 Female 174 lb 1/9/2009 Consumer United States
Primary
Concomitant
Dermatitis Allergic Other Serious 1/12/2009 1/14/2009 Pharmacist Greece
Primary
Concomitant
Vomiting Hospitalization 12/1/2008 Female 126 lb 1/23/2009 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 6/1/1999 47 Male 160 lb 1/30/2009 Consumer United States
Primary
Concomitant
Oral Disorder Other Serious 10/1/2004 Male 2/2/2009 Consumer United States
Primary
Concomitant
Erythrodermic Psoriasis Death 8/15/2008 Male 209 lb 2/9/2009 United Kingdom
Primary
Concomitant
Oesophageal Obstruction Hospitalization 2/8/2009 82 Female 156 lb 2/11/2009 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2002 2/14/2009 Physician United States
Primary
Secondary
Concomitant
Tooth Disorder Hospitalization 8/1/2008 Female 2/17/2009 Consumer United States
Primary
Concomitant
Urticaria 9/13/2008 Male 2/24/2009 United States
Primary
Concomitant
Liver Function Test Abnormal 12/5/2008 Male 2/24/2009 United States
Primary
Concomitant
Swollen Tongue Other Serious 12/1/2008 Female 3/2/2009 Physician United States
Primary
Secondary
Concomitant
Asthenia 10/31/2008 68 Male 3/4/2009 Consumer United States
Primary
Concomitant
Tendon Disorder Other Serious 1/1/2005 72 Female 139 lb 3/9/2009 Physician United States
Primary
Concomitant
Oral Disorder Other Serious 10/1/2004 Male 3/13/2009 Consumer United States
Primary
Concomitant
Suicide Attempt Hospitalization 7/1/2008 48 Female 201 lb 3/5/2009 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2006 68 Male 165 lb 3/16/2009 Consumer United States
Primary
Concomitant
Tendon Disorder Other Serious 1/1/2005 72 Female 139 lb 3/26/2009 Physician United States
Primary
Concomitant
Pulmonary Thrombosis Other Serious 9/1/2008 Male 215 lb 3/26/2009 Consumer United States
Primary
Concomitant
Tendon Disorder Other Serious 1/1/2005 72 Female 139 lb 3/31/2009 Physician United States
Primary
Concomitant
Chest Pain Other Serious 49 Male 4/1/2009 Consumer Canada
Primary
Concomitant
Dermatitis Allergic Other Serious 1/12/2009 4/2/2009 Pharmacist Greece
Primary
Concomitant
Pulmonary Thrombosis Other Serious 9/1/2008 Male 215 lb 4/9/2009 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 5/19/1999 47 Female 160 lb 4/14/2009 United States
Primary
Concomitant
Somnolence 1/1/2009 Female 4/23/2009 Consumer
Primary
Concomitant
Lymphangioma Other Serious 7/1/2005 4/24/2009 Other Health Professional Germany
Primary
Concomitant
Erythrodermic Psoriasis Death 8/15/2008 Male 209 lb 4/29/2009 United Kingdom
Primary
Concomitant
Viral Infection Hospitalization Female 105 lb 4/30/2009 Consumer United States
Primary
Concomitant
Trigeminal Neuralgia Other Serious 7/1/2005 5/6/2009 Other Health Professional Germany
Primary
Concomitant
Diplopia Hospitalization 2/26/2009 70 5/15/2009 Physician Italy
Primary
Concomitant
Flushing Other Serious 4/1/2009 Male 199 lb 5/19/2009 United States
Primary
Concomitant
Vulvovaginal Pruritus Other Serious 12/1/2003 43 Female 134 lb 5/20/2009 United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2002 5/20/2009 Physician United States
Primary
Secondary
Concomitant
Blood Glucose Abnormal Female 5/27/2009 United States
Primary
Concomitant
Trigeminal Neuralgia Other Serious 7/1/2005 35 6/4/2009 Physician Germany
Primary
Concomitant
Diplopia Hospitalization 2/26/2009 70 6/5/2009 Physician Italy
Primary
Concomitant
Drug Dose Omission 5/12/2009 Female 240 lb 6/12/2009 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 11/25/2007 Female 6/12/2009 Belgium
Primary
Secondary
Concomitant
Tremor Other Serious 1/1/2009 Female 181 lb 6/16/2009 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization 1/26/2009 89 Female 148 lb 6/12/2009 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 11/25/2007 Female 6/26/2009 Belgium
Primary
Secondary
Concomitant
Diplopia Hospitalization 2/26/2009 70 7/1/2009 Physician Italy
Primary
Concomitant
Trigeminal Neuralgia Other Serious 7/1/2005 35 7/10/2009 Physician Germany
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 6/1/2009 87 Female 195 lb 7/14/2009 Consumer United States
Primary
Concomitant
Toxic Encephalopathy Hospitalization 5/20/2009 50 Female 7/16/2009 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 50 Female 170 lb 7/16/2009 United States
Primary
Concomitant
Tremor Other Serious 1/1/2009 Female 181 lb 7/17/2009 Physician United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 6/1/2009 87 Female 195 lb 7/24/2009 Consumer United States
Primary
Concomitant
Pancreatitis Other Serious 6/24/2009 Male 7/27/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2002 41 Male 332 lb 7/30/2009 United States
Primary
Concomitant
Vomiting Hospitalization 72 Female 7/22/2009 Lawyer United States
Primary
Concomitant
Toxic Encephalopathy Hospitalization 5/20/2009 50 Female 8/7/2009 Other Health Professional United States
Primary
Concomitant
Sepsis Other Serious 6/29/2009 Male 8/7/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 12/6/2007 72 Female 8/5/2009 United States
Primary
Concomitant
Faeces Discoloured 8/1/2009 Female 8/21/2009 Consumer
Primary
Concomitant
Flushing Female 8/22/2009 United States
Primary
Concomitant

Drug Data