Depakote combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cardiomyopathy Hospitalization 3/17/2006 45 Male 192 lb 3/31/2006 Pharmacist United States
Primary
Concomitant
Agitation Hospitalization 4/1/2006 Male 280 lb 4/14/2006 Physician United States
Primary
Concomitant
Refusal Of Treatment By Patient Hospitalization 4/1/2006 Male 280 lb 4/26/2006 Physician United States
Primary
Concomitant
Agitation Hospitalization 4/1/2006 Male 280 lb 6/15/2006 Physician United States
Primary
Concomitant
Urticaria Required Intervention 6/27/2006 61 Male 160 lb 6/28/2006 Pharmacist United States
Primary
Concomitant
Pneumonia 1/1/2006 54 Female 166 lb 7/12/2006 Consumer United States
Primary
Concomitant
Agitation Hospitalization 4/1/2006 Male 280 lb 8/16/2006 Physician United States
Primary
Concomitant
Oral Mucosal Blistering Hospitalization 8/29/2006 48 Male 202 lb 9/7/2006 Pharmacist United States
Primary
Concomitant
Skin Exfoliation Hospitalization 8/29/2006 48 Male 202 lb 9/28/2006 Pharmacist United States
Primary
Concomitant
Myocardial Ischaemia Death 8/1/2006 66 Male 187 lb 10/4/2006 United Kingdom
Primary
Concomitant
Convulsion Other Serious 8/1/2006 42 Male 11/2/2006 Consumer United States
Primary
Concomitant
Feeling Abnormal Other Serious 11/7/2006 52 Female 175 lb 11/22/2006 United States
Primary
Concomitant
Drug Ineffective Hospitalization 1/3/2007 Female 148 lb 2/6/2007 Consumer United States
Primary
Secondary
Concomitant
Sedation Other Serious 9/1/2006 46 Male 225 lb 2/6/2007 Pharmacist United States
Primary
Concomitant
Respiratory Failure Other Serious 1/1/2005 62 Male 3/27/2007 Physician United States
Primary
Concomitant
Insomnia 6/1/2006 52 Female 1/12/2007 Pharmacist United States
Primary
Concomitant
Repetitive Speech Other Serious 1/3/2007 80 Female 6/4/2007 Other Health Professional France
Primary
Concomitant
Vision Blurred Other Serious 6/5/2007 51 Male 8/14/2007 Physician United Kingdom
Primary
Concomitant
Tremor 1/1/2007 50 Male 189 lb 9/5/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 7/5/2007 53 Female 177 lb 8/31/2007 Physician United States
Primary
Concomitant
Malaise Other Serious 6/12/2007 40 Male 9/10/2007 United Kingdom
Primary
Secondary
Concomitant
Malaise Other Serious 1/1/2007 40 Male 9/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Malaise Other Serious 1/1/2007 40 Male 9/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 7/1/2007 Female 9/19/2007 Consumer United States
Primary
Concomitant
Malaise Other Serious 1/1/2007 40 Male 10/4/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 2/4/2006 Male 10/5/2007 United States
Primary
Secondary
Concomitant
Tremor Hospitalization 1/1/2007 Female 187 lb 10/30/2007 Consumer United States
Primary
Secondary
Concomitant
Tremor Hospitalization 1/1/2007 Female 187 lb 11/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 9/1/2007 Female 190 lb 1/17/2008 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 9/1/2007 Female 190 lb 2/15/2008 Consumer United States
Primary
Concomitant
Neutropenia Hospitalization 1/8/2008 Female 117 lb 2/25/2008 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 2/1/2008 Male 214 lb 2/27/2008 Consumer United States
Primary
Concomitant
Metastatic Neoplasm Hospitalization 2/22/2008 Female 153 lb 3/13/2008 Other Health Professional United States
Primary
Concomitant
Tremor Other Serious 1/1/2005 Male 168 lb 4/4/2008 Physician United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 9/1/2007 Female 190 lb 4/10/2008 Physician United States
Primary
Concomitant
Somnolence Other Serious 12/1/2006 Male 225 lb 6/27/2008 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 6/1/2008 Male 230 lb 6/30/2008 Physician United States
Primary
Concomitant
Interacting
Vision Blurred Other Serious 6/1/2008 Male 230 lb 7/2/2008 Physician United States
Primary
Concomitant
Interacting
Scrotal Swelling Other Serious 11/1/2007 Male 8/15/2008 Consumer United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 7/24/2008 72 Male 8/22/2008 Other Health Professional United States
Primary
Concomitant
Sepsis Hospitalization 8/28/2008 Female 270 lb 9/12/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 250 lb 9/19/2008 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 5/1/2008 67 Female 9/29/2008 Physician France
Primary
Concomitant
Pain Hospitalization 8/28/2008 51 Female 145 lb 9/19/2008 Other Health Professional United States
Primary
Concomitant
Urine Sodium Decreased Hospitalization 3/15/2008 Female 10/1/2008 Other Health Professional France
Primary
Secondary
Concomitant
Myocardial Infarction Death Male 9/29/2008 Pharmacist United States
Primary
Concomitant
Respiratory Distress Life Threatening 8/20/2008 51 236 lb 10/6/2008 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 9/1/2008 Female 195 lb 10/23/2008 Consumer United States
Primary
Concomitant
Interacting
Vomiting Other Serious 9/1/2008 Female 195 lb 10/24/2008 Consumer United States
Primary
Concomitant
Interacting
Nausea 1/1/2008 68 Female 9/2/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Death 11/21/2008 88 Male 148 lb 12/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Poisoning Hospitalization 8/16/2008 Male 189 lb 11/25/2008 Other Health Professional United States
Primary
Concomitant
Sepsis Hospitalization 8/28/2008 Female 270 lb 12/31/2008 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation Other Serious 58 Female 1/28/2009 Physician United Kingdom
Primary
Concomitant
Suicidal Ideation Hospitalization 58 Female 2/5/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization 58 Female 2/5/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 1/1/2008 58 Female 2/11/2009 Other Health Professional France
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization 58 Female 2/5/2009 Physician United Kingdom
Primary
Concomitant
Suicidal Ideation Hospitalization 58 Female 2/5/2009 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Death 11/21/2008 88 Male 148 lb 12/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Hospitalization Female 2/27/2009 Consumer United States
Primary
Concomitant
Vomiting 7/1/2007 Female 238 lb 3/12/2009 Pharmacist United States
Primary
Concomitant
Medication Residue Male 3/12/2009 Pharmacist United States
Primary
Concomitant
Parkinson's Disease 10/1/2005 3/12/2009 Other Health Professional United States
Primary
Concomitant
Vision Blurred 12/6/2008 Female 130 lb 3/12/2009 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious 3/3/2009 60 Female 3/23/2009 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 2/11/2009 Female 173 lb 3/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 6/11/2004 53 Male 204 lb 4/1/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/5/2002 47 Male 195 lb 4/3/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 5/19/1999 47 Female 160 lb 4/14/2009 United States
Primary
Concomitant
Wound Other Serious 4/6/2009 54 Female 143 lb 5/18/2009 Other Health Professional United States
Primary
Concomitant
Pancreatitis Hospitalization 3/25/2009 54 Female 143 lb 5/18/2009 Other Health Professional United States
Primary
Concomitant
Viral Upper Respiratory Tract Infection Hospitalization 4/26/2000 35 Male 230 lb 5/20/2009 United States
Primary
Concomitant
Agranulocytosis Life Threatening 1/7/2009 45 Male 2/18/2009 Other Health Professional United States
Primary
Concomitant
Volvulus Hospitalization 1/1/2008 Female 270 lb 7/14/2009 Other Health Professional United States
Primary
Concomitant
Pancreatitis Other Serious 9/11/2002 39 Female 107 lb 7/22/2009 United States
Primary
Concomitant
Traumatic Brain Injury Other Serious 1/1/2003 40 Male 209 lb 7/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1998 41 Male 303 lb 7/30/2009 United States
Primary
Concomitant
Hyperhidrosis Female 8/22/2009 United States
Primary
Concomitant
Parkinson's Disease Required Intervention 4/13/2009 46 Female 260 lb 8/28/2009 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 2/1/2009 Female 214 lb 9/3/2009 Consumer United States
Primary
Concomitant
Pallor Hospitalization 5/21/2009 58 Male 9/10/2009 Physician United Kingdom
Primary
Concomitant
Pallor Hospitalization 5/21/2009 58 Male 9/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pain Hospitalization 67 Male 9/8/2009 United States
Primary
Concomitant
Somnolence Other Serious 3/29/2009 29 Male 9/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization 12/10/2007 58 Female 9/15/2009 United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious Male 210 lb 9/23/2009 United States
Primary
Concomitant
Vision Blurred Other Serious 10/1/2005 51 Female 194 lb 9/23/2009 United States
Primary
Concomitant
Obesity Other Serious 1/1/2000 50 Male 246 lb 9/30/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 3/22/2005 53 Female 196 lb 10/1/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 67 Male 9/24/2009 United States
Primary
Concomitant
Tardive Dyskinesia Other Serious 12/29/2006 59 Male 303 lb 10/8/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2001 44 Male 262 lb 10/14/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 51 Male 286 lb 10/15/2009 United States
Primary
Concomitant
Pain Hospitalization 67 Male 10/9/2009 United States
Primary
Concomitant
Vomiting Required Intervention 8/29/2008 58 Female 11/6/2009 Lawyer United States
Primary
Concomitant
Rib Fracture Hospitalization 67 Male 11/18/2009 United States
Primary
Concomitant
Syncope Hospitalization 5/1/2008 67 Female 12/1/2009 Physician France
Primary
Concomitant
Suicidal Ideation Other Serious 58 Female 12/1/2009 Physician United Kingdom
Primary
Concomitant
Myalgia 8/1/2009 68 Male 190 lb 12/9/2009 Consumer United States
Primary
Concomitant
Uterine Polyp Other Serious 7/29/1998 37 Female 182 lb 12/17/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 41 Male 12/30/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 3/1/2008 61 Male 224 lb 1/22/2010 United States
Primary
Concomitant
Somnolence Other Serious 3/25/2009 29 Male 1/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2002 56 Male 224 lb 1/25/2010 United States
Primary
Concomitant
Postictal State Other Serious 12/7/2008 Male 1/22/2010 Physician United States
Primary
Secondary
Concomitant
Vascular Anomaly Other Serious 56 Male 180 lb 2/4/2010 Physician United States
Primary
Secondary
Concomitant
Vascular Anomaly Other Serious 56 Male 180 lb 2/10/2010 Consumer United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2002 56 Male 224 lb 2/11/2010 United States
Primary
Concomitant
Postictal State Other Serious 12/7/2008 Male 2/5/2010 Physician United States
Primary
Secondary
Concomitant
Mania Hospitalization 12/24/2009 Female 260 lb 2/23/2010 Consumer United States
Primary
Concomitant
Haematuria Life Threatening 10/28/2009 68 Male 199 lb 2/16/2010 Physician United States
Primary
Concomitant
Delirium 2/20/2009 76 Male 148 lb 3/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Mania Hospitalization 12/24/2009 Female 260 lb 3/2/2010 Consumer United States
Primary
Concomitant
Mania Hospitalization 12/24/2009 Female 260 lb 3/3/2010 Consumer United States
Primary
Concomitant
High Density Lipoprotein Decreased 2/1/2010 210 lb 3/16/2010 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2003 Female 220 lb 3/30/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 12/29/1997 46 Female 214 lb 3/29/2010 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2003 56 Female 220 lb 4/5/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/13/2003 66 Male 174 lb 4/14/2010 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2003 57 Female 220 lb 4/15/2010 Consumer United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 41 Male 4/19/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2003 57 Female 220 lb 4/20/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2003 57 Female 220 lb 4/27/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2003 57 Female 220 lb 4/27/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/13/2003 66 Male 174 lb 5/3/2010 United States
Primary
Concomitant
Weight Increased Hospitalization 12/29/1997 46 Female 214 lb 6/1/2010 Physician United States
Primary
Concomitant
Wheezing Hospitalization 81 Male 6/2/2010 United States
Primary
Concomitant
Viral Infection Other Serious 3/1/2010 40 Female 185 lb 6/11/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/13/2003 66 Male 174 lb 6/15/2010 United States
Primary
Concomitant
High Density Lipoprotein Decreased 2/1/2010 56 210 lb 6/16/2010 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 5/27/2003 38 Male 215 lb 6/17/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/13/2003 66 Male 174 lb 6/23/2010 United States
Primary
Concomitant
Granulocytopenia Other Serious 5/7/2009 51 Female 6/24/2010 United States
Primary
Concomitant
Granulocytopenia Other Serious 10/6/2009 47 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Off Label Use Other Serious 12/1/2008 56 Male 7/1/2010 Physician Switzerland
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 41 Male 246 lb 7/2/2010 United States
Primary
Concomitant
Overdose Other Serious Male 6/25/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2003 57 Female 220 lb 7/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor 1/1/2007 65 Female 145 lb 7/7/2010 Consumer United States
Primary
Secondary
Concomitant
Nausea 1/1/2007 50 Female 7/16/2010 Consumer United States
Primary
Concomitant
Fatigue Female 180 lb 7/17/2010 Consumer United States
Primary
Concomitant
Vomiting 11/1/2007 60 Female 110 lb 7/17/2010 Consumer United States
Primary
Concomitant
Headache 11/13/2007 60 Female 110 lb 7/17/2010 Consumer United States
Primary
Concomitant
Mood Swings 12/1/2007 59 Male 230 lb 7/17/2010 Consumer United States
Primary
Concomitant
Vomiting 1/1/2008 71 Male 260 lb 7/19/2010 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 9/11/2002 39 Female 107 lb 7/26/2010 United States
Primary
Concomitant
Wound Other Serious 3/13/2003 66 Male 174 lb 7/28/2010 United States
Primary
Concomitant
Nervousness Other Serious 1/1/2010 54 Female 134 lb 7/30/2010 Consumer Brazil
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 9/11/2002 39 Female 107 lb 8/5/2010 United States
Primary
Concomitant

Drug Data