Estradiol combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ventricular Extrasystoles Other Serious 3/8/2005 Female 1/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Headache Other Serious 2/10/2006 49 Female 170 lb 3/15/2006 United Kingdom
Primary
Secondary
Concomitant
Headache Other Serious 2/10/2006 49 Female 170 lb 3/15/2006 United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 9/1/2001 70 Female 126 lb 4/14/2006 Physician Canada
Primary
Concomitant
Myocardial Infarction Hospitalization 4/1/2003 63 Female 168 lb 5/11/2006 Lawyer United States
Primary
Concomitant
Therapy Cessation Other Serious 68 Female 7/13/2006 United States
Primary
Secondary
Concomitant
Respiratory Disorder Other Serious 53 Female 132 lb 12/12/2006 United Kingdom
Primary
Concomitant
Tachycardia Hospitalization 10/16/2006 55 Female 12/13/2006 Other Health Professional Netherlands
Primary
Concomitant
Insomnia 8/1/2005 57 Female 120 lb 10/11/2006 Consumer United States
Primary
Concomitant
Mood Swings 9/1/2006 45 Female 11/10/2006 Consumer United States
Primary
Concomitant
Small Intestinal Perforation Hospitalization 10/16/2006 55 Female 2/15/2007 Other Health Professional Netherlands
Primary
Concomitant
Hypotrichosis 1/1/2006 66 Female 132 lb 1/12/2007 Consumer United States
Primary
Concomitant
Insomnia 1/1/2006 81 Female 125 lb 1/12/2007 Consumer United States
Primary
Secondary
Concomitant
Small Intestinal Perforation Hospitalization 10/16/2006 55 Female 5/7/2007 Other Health Professional Netherlands
Primary
Concomitant
Vomiting Other Serious 4/1/2007 45 Female 4/26/2007 United States
Primary
Concomitant
Vision Blurred Other Serious 5/1/2007 52 Female 135 lb 5/30/2007 Consumer United States
Primary
Concomitant
Nasal Congestion Hospitalization 4/13/2007 52 Female 210 lb 6/12/2007 Other Health Professional United States
Primary
Concomitant
Nasal Congestion Hospitalization 4/13/2007 52 Female 210 lb 6/12/2007 Other Health Professional United States
Primary
Concomitant
Nipple Exudate Bloody Other Serious 1/1/2004 Female 180 lb 9/17/2007 Consumer United States
Primary
Secondary
Concomitant
Vaginal Haemorrhage Other Serious 57 Female 148 lb 10/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Small Intestinal Perforation Hospitalization 10/16/2006 55 Female 10/10/2007 Other Health Professional Netherlands
Primary
Concomitant
Therapeutic Response Decreased 5/17/2007 60 Female 243 lb 10/24/2007 Physician United States
Primary
Secondary
Concomitant
Food Allergy Other Serious 11/14/2007 Female 11/30/2007 Physician United States
Primary
Concomitant
Pruritus 8/13/2007 Female 12/14/2007 Physician United States
Primary
Concomitant
Throat Irritation Female 12/28/2007 Consumer United States
Primary
Concomitant
Hypersensitivity Other Serious 11/14/2007 Female 1/21/2008 Physician United States
Primary
Concomitant
Polyuria Disability 9/1/2006 2/21/2008 Other Health Professional United Kingdom
Primary
Concomitant
Polyuria Disability 9/1/2006 48 Female 245 lb 2/16/2008 United Kingdom
Primary
Concomitant
Low Density Lipoprotein Increased Hospitalization 3/1/2007 50 Female 150 lb 3/7/2008 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 4/7/2008 Female 141 lb 4/25/2008 Physician United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 4/7/2008 Female 141 lb 5/1/2008 Physician United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 4/7/2008 Female 141 lb 5/21/2008 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 1/1/2005 Female 144 lb 5/15/2008 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2005 Female 144 lb 5/22/2008 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 4/7/2008 Female 141 lb 6/4/2008 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2005 Female 143 lb 5/30/2008 Physician United States
Primary
Concomitant
Injection Site Vesicles Female 6/12/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/7/2008 Female 141 lb 6/18/2008 Physician United Kingdom
Primary
Concomitant
Condition Aggravated Female 8/1/2008 Consumer United States
Primary
Concomitant
Rash Papular 2/1/2008 Female 137 lb 9/12/2008 United States
Primary
Concomitant
Urticaria Other Serious 1/19/2008 41 Female 218 lb 9/10/2008 Other Health Professional United States
Primary
Concomitant
Urticaria Other Serious 1/19/2008 41 Female 218 lb 9/10/2008 Other Health Professional United States
Primary
Concomitant
Paraesthesia Hospitalization 10/11/2007 49 Female 12/10/2007 Physician United States
Primary
Concomitant
Wheezing Other Serious 4/12/2008 62 Female 138 lb 10/10/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 10/8/2008 65 Female 130 lb 10/20/2008 Other Health Professional United States
Primary
Concomitant
Pain 9/30/2008 67 Female 10/31/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 10/8/2008 65 Female 130 lb 11/4/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 10/8/2008 65 Female 130 lb 11/6/2008 Physician United States
Primary
Concomitant
Pancreatitis Other Serious 1/1/1981 Female 140 lb 11/22/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 10/8/2008 65 Female 130 lb 11/19/2008 Physician United States
Primary
Concomitant
Arthralgia Female 182 lb 11/26/2008 United States
Primary
Concomitant
Injection Site Irritation Female 12/15/2008 Pharmacist United States
Primary
Concomitant
Streptococcal Infection Life Threatening Female 12/29/2008 Physician United States
Primary
Concomitant
Somnolence Other Serious 1/1/2009 72 Female 132 lb 5/15/2009 Consumer United States
Primary
Concomitant
Weight Increased 3/1/2009 Female 188 lb 6/12/2009 United States
Primary
Concomitant
Urinary Tract Infection 10/1/2008 264 lb 6/12/2009 United States
Primary
Concomitant
Somnolence Other Serious 1/1/2009 72 Female 132 lb 6/19/2009 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/28/2009 Female 265 lb 8/13/2009 Physician United States
Primary
Secondary
Concomitant
Nervousness 1/1/2009 84 Female 86 lb 8/17/2009 Physician United States
Primary
Secondary
Therapeutic Agent Toxicity Hospitalization 68 Female 8/13/2009 Consumer United States
Primary
Concomitant
Oedema Peripheral Female 8/21/2009 United States
Primary
Concomitant
Sinus Tachycardia Female 134 lb 8/22/2009 Consumer United States
Primary
Concomitant
Skin Burning Sensation Female 8/22/2009 United States
Primary
Concomitant
Sensory Disturbance 5/1/2009 Female 160 lb 8/22/2009 United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/28/2009 Female 265 lb 8/25/2009 Physician United States
Primary
Secondary
Concomitant
Rash Generalised 8/1/2008 Female 169 lb 8/25/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 62 Female 8/25/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/23/2009 Lawyer United States
Primary
Concomitant
Swelling 7/7/2009 59 Female 219 lb 8/7/2009 Consumer United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 9/17/2009 United States
Primary
Concomitant
Vomiting Hospitalization 56 Female 9/17/2009 United States
Primary
Concomitant
Vomiting Hospitalization 53 Female 9/24/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 4/23/2007 54 Female 258 lb 9/24/2009 United States
Primary
Concomitant
Nervousness 1/1/2009 84 Female 86 lb 10/6/2009 Physician United States
Primary
Secondary
Glossodynia 9/21/2009 60 Female 251 lb 10/22/2009 Consumer United States
Primary
Concomitant
Anaphylactic Reaction Other Serious 10/11/2007 62 Female 10/23/2009 United Kingdom
Primary
Concomitant
Vomiting Other Serious 2/21/2008 69 Female 150 lb 10/29/2009 Lawyer United States
Primary
Concomitant
Throat Irritation 9/1/2009 71 Female 110 lb 11/2/2009 Consumer United States
Primary
Concomitant
Rhabdomyolysis Other Serious 11/3/2009 Female 190 lb 11/5/2009 United States
Primary
Concomitant
Vomiting Hospitalization 53 Female 11/4/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 4/23/2007 54 Female 258 lb 11/18/2009 United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2005 Female 143 lb 12/1/2009 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/28/2009 Female 265 lb 12/15/2009 Physician United States
Primary
Secondary
Concomitant
Uterine Polyp Other Serious 7/29/1998 37 Female 182 lb 12/17/2009 United States
Primary
Concomitant
Rash Erythematous Female 1/11/2010 United States
Primary
Concomitant
Skin Cancer Other Serious 2/1/2008 Female 137 lb 1/28/2010 United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 8/1/2009 Female 198 lb 3/12/2010 Physician Denmark
Primary
Concomitant
Interstitial Lung Disease Hospitalization 8/1/2009 Female 198 lb 3/10/2010 Physician Denmark
Primary
Concomitant
Syncope Other Serious 5/1/2006 Female 206 lb 3/17/2010 Physician United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 8/1/2009 Female 198 lb 3/23/2010 Other Health Professional Denmark
Primary
Concomitant
Weight Increased Other Serious 7/1/1999 Female 3/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/1/1999 60 Female 4/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 2/21/2008 69 Female 150 lb 4/13/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 53 Female 4/15/2010 United States
Primary
Concomitant
Weight Increased Other Serious 7/1/1999 60 Female 4/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 2/21/2008 69 Female 150 lb 5/5/2010 Other Health Professional United States
Primary
Concomitant
Product Quality Issue Other Serious 61 Female 5/10/2010 Consumer United States
Primary
Concomitant
Product Quality Issue Other Serious 61 Female 5/14/2010 Consumer United States
Primary
Concomitant
Laboratory Test Abnormal Female 210 lb 5/17/2010 United States
Primary
Concomitant
Pain In Extremity Other Serious 85 Female 135 lb 5/18/2010 Consumer United States
Primary
Concomitant
Syncope Other Serious 5/1/2010 67 Female 122 lb 5/20/2010 Consumer United States
Primary
Concomitant
Reaction To Drug Excipients Other Serious 11/1/2009 65 Female 168 lb 5/19/2010 Consumer United States
Primary
Concomitant
Tongue Coated Female 5/28/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 29 Female 143 lb 6/4/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process 6/16/2010 54 Female 214 lb 6/28/2010 Consumer United States
Primary
Concomitant
Syncope Other Serious 5/1/2006 36 Female 206 lb 6/29/2010 Physician United States
Primary
Concomitant
Tremor 1/1/2009 55 Female 154 lb 7/7/2010 Physician United States
Primary
Concomitant
Toothache Other Serious 1/1/2008 38 Female 175 lb 7/9/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 7/1/1999 60 Female 7/12/2010 United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 9/26/2008 56 Female 150 lb 7/16/2010 Consumer United States
Primary
Secondary
Concomitant
Product Quality Issue Other Serious 61 Female 7/16/2010 Consumer United States
Primary
Concomitant
Nausea Female 170 lb 7/17/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 12/10/2009 42 Female 174 lb 7/20/2010 Consumer United Kingdom
Primary
Concomitant
Nausea 3/19/2008 49 Female 130 lb 7/21/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 12/10/2009 42 Female 174 lb 7/30/2010 Physician United Kingdom
Primary
Concomitant
Pain 5/1/2009 78 Female 145 lb 7/31/2010 Consumer United States
Primary
Secondary
Concomitant
Skin Warm 5/12/2007 58 Female 156 lb 8/2/2010 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 2/21/2008 69 Female 150 lb 8/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Dry Mouth 10/1/2007 Female 8/2/2010 Consumer United States
Primary
Concomitant
Suicide Attempt Other Serious 6/14/2007 44 Female 8/4/2010 Lawyer United States
Primary
Concomitant
Impaired Work Ability Disability 7/21/2010 61 Female 120 lb 8/5/2010 Consumer United States
Primary
Concomitant
Pain In Extremity Other Serious 9/26/2008 56 Female 150 lb 8/11/2010 Consumer United States
Primary
Secondary
Concomitant
Syncope Other Serious 5/1/2010 67 Female 122 lb 8/11/2010 Consumer United States
Primary
Concomitant
Syncope Other Serious 5/1/2006 36 Female 206 lb 8/17/2010 Physician United States
Primary
Concomitant
Vertigo Other Serious 62 Female 182 lb 8/16/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 7/1/1999 60 Female 8/25/2010 United States
Primary
Secondary
Concomitant
Vision Blurred 12/4/2009 75 Female 195 lb 8/28/2010 Consumer United States
Primary
Concomitant
Pruritus 6/16/2010 51 Female 200 lb 8/29/2010 Consumer United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/1998 65 Female 104 lb 9/7/2010 Consumer United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 45 Female 257 lb 9/8/2010 Other Health Professional United States
Primary
Concomitant
Low Density Lipoprotein Increased Hospitalization 3/1/2007 50 Female 150 lb 9/9/2010 Consumer United States
Primary
Secondary
Concomitant
Tinnitus 3/1/2009 60 Female 170 lb 9/9/2010 Physician United States
Primary
Secondary
Concomitant
Sedation Other Serious 7/21/2010 61 Female 120 lb 9/10/2010 Physician United States
Primary
Concomitant
Death Death 9/1/2010 59 Female 239 lb 9/14/2010 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 4/30/2010 74 Male 9/16/2010 Physician United States
Primary
Concomitant
Skin Ulcer Hospitalization 7/14/2010 81 Female 215 lb 9/29/2010 Other Health Professional Sweden
Primary
Concomitant
Viral Infection Other Serious 50 Female 10/1/2010 United Kingdom
Primary
Secondary
Concomitant
Contusion Other Serious Female 125 lb 9/29/2010 United States
Primary
Concomitant
Vomiting Other Serious 7/1/1999 60 Female 10/12/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3/10/2010 67 Female 10/19/2010 Consumer United States
Primary
Concomitant
Viral Infection Other Serious 50 Female 10/18/2010 United Kingdom
Primary
Secondary
Concomitant
Headache 1/1/2010 55 Female 181 lb 10/28/2010 Physician United States
Primary
Concomitant
Prolonged Expiration Other Serious 7/22/2010 57 Female 124 lb 10/14/2010 Pharmacist United States
Primary
Secondary
Concomitant
Drug Effect Decreased 81 Female 112 lb 10/29/2010 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 11/29/2006 63 Female 210 lb 11/9/2010 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 10/21/2010 71 Female 165 lb 11/15/2010 Physician Germany
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 2/21/2008 69 Female 150 lb 12/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 8/4/2010 70 Female 159 lb 12/15/2010 United States
Primary
Concomitant
Nervous System Disorder Other Serious Female 12/15/2010 Consumer United States
Primary
Concomitant
Nasal Congestion 11/23/2009 12/15/2010 Consumer United States
Primary
Concomitant

Drug Data