Simvastatin combined with Tasigna

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Stent Placement Hospitalization 5/1/2006 64 Male 176 lb 4/23/2008 Physician Germany
Primary
Concomitant
Stent Placement Hospitalization 5/1/2006 64 Male 176 lb 5/15/2008 Physician Germany
Primary
Concomitant
Vision Blurred 4/1/2008 67 Female 156 lb 5/5/2008 Physician United States
Primary
Concomitant
Rhabdomyolysis Other Serious 1/1/2009 Female 4/9/2009 Physician Austria
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/1/2009 Female 4/17/2009 Physician Austria
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious 1/27/2009 64 Male 4/27/2009 Physician Oman
Primary
Concomitant
Rhabdomyolysis Other Serious 1/1/2009 Female 132 lb 4/30/2009 Physician Austria
Primary
Secondary
Concomitant
Troponin T Increased Hospitalization 8/1/2008 Male 152 lb 5/28/2009 Physician France
Primary
Concomitant
Medication Error Hospitalization Male 6/18/2009 Pharmacist United States
Primary
Concomitant
Death Death 4/14/2009 Male 6/30/2009 United States
Primary
Concomitant
Malignant Neoplasm Progression Death 4/14/2009 Male 7/10/2009 United States
Primary
Concomitant
Medication Error Other Serious Male 8/20/2009 United States
Primary
Concomitant
Tubulointerstitial Nephritis Hospitalization 7/1/2009 Female 10/9/2009 Other Health Professional Netherlands
Primary
Concomitant
Tubulointerstitial Nephritis Hospitalization 7/1/2009 Female 10/30/2009 Other Health Professional Netherlands
Primary
Concomitant
Urine Output Decreased Hospitalization 7/1/2009 Female 165 lb 11/13/2009 Other Health Professional Netherlands
Primary
Concomitant
Pain Life Threatening 8/1/2009 Male 11/26/2009 Physician Sweden
Primary
Concomitant
Renal Cancer Hospitalization Male 220 lb 12/29/2009 Physician France
Primary
Concomitant
Pain Life Threatening 8/1/2009 Male 3/8/2010 Physician Sweden
Primary
Concomitant
Pain Life Threatening 8/1/2009 Male 3/31/2010 Physician Sweden
Primary
Concomitant
Renal Cancer Other Serious 1/1/2008 66 Male 4/9/2010 Physician France
Primary
Secondary
Concomitant
Renal Cancer Hospitalization Male 220 lb 4/13/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Cancer Hospitalization Male 220 lb 4/13/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Cancer Hospitalization 6/1/2009 Male 220 lb 6/17/2010 Physician France
Primary
Secondary
Concomitant
Neutropenia Female 176 lb 7/22/2010 Physician United Kingdom
Primary
Concomitant
Supraventricular Extrasystoles Hospitalization 7/17/2009 60 Female 7/23/2010 Physician Japan
Primary
Concomitant
Gastric Ph Increased 3/11/2008 74 Male 8/17/2010 United States
Primary
Concomitant
Renal Cancer Hospitalization 6/1/2009 66 Male 220 lb 9/16/2010 Other Health Professional France
Primary
Secondary
Concomitant
Syncope Other Serious 9/1/2010 56 Male 9/21/2010 Physician United States
Primary
Concomitant
Renal Cancer Hospitalization 6/1/2009 Male 220 lb 9/21/2010 Physician France
Primary
Secondary
Concomitant
Sudden Death Death Male 280 lb 10/5/2010 Physician Brazil
Primary
Concomitant
Percutaneous Coronary Intervention Other Serious 4/7/2010 81 Female 10/6/2010 Physician Austria
Primary
Concomitant
Sudden Death Other Serious 9/29/2010 60 Male 280 lb 10/13/2010 Physician Brazil
Primary
Concomitant
Sudden Death Other Serious 9/29/2010 60 Male 280 lb 10/19/2010 Physician Brazil
Primary
Concomitant
Sudden Death Other Serious 9/29/2010 60 Male 280 lb 10/21/2010 Physician Brazil
Primary
Concomitant
Sudden Death Other Serious 9/29/2010 60 Male 280 lb 11/1/2010 Physician Brazil
Primary
Concomitant
Supraventricular Extrasystoles Hospitalization 7/17/2009 60 Female 11/15/2010 Physician Japan
Primary
Concomitant
Peripheral Arterial Occlusive Disease Other Serious 10/29/2010 76 Male 209 lb 12/29/2010 Physician Austria
Primary
Concomitant
Toe Amputation Other Serious 4/1/2010 78 Male 218 lb 12/31/2010 Physician France
Primary
Concomitant
Dry Skin Hospitalization 10/1/2009 72 Female 143 lb 1/25/2011 Physician Germany
Primary
Concomitant
Weight Decreased Hospitalization 1/12/2011 91 Male 143 lb 3/1/2011 Physician United Kingdom
Primary
Concomitant
Diabetic Complication Hospitalization Female 3/21/2011 Physician United States
Primary
Concomitant
Coronary Artery Stenosis Other Serious 4/7/2010 81 Female 139 lb 3/22/2011 Physician Austria
Primary
Concomitant
Fall Hospitalization Female 4/5/2011 Physician United States
Primary
Concomitant
Coronary Artery Stenosis Other Serious 4/7/2010 81 Female 139 lb 4/18/2011 Physician Austria
Primary
Concomitant
Headache Male 4/21/2011 United States
Primary
Concomitant
Arteriosclerosis Coronary Artery Other Serious 4/7/2010 81 Female 139 lb 5/2/2011 Physician Austria
Primary
Concomitant
Conjunctivitis 9/30/2010 59 Male 5/3/2011 Physician United States
Primary
Concomitant
Headache Other Serious 4/11/2011 67 Male 220 lb 5/6/2011 Consumer United States
Primary
Concomitant
Flatulence Other Serious 2/27/2010 80 Female 137 lb 5/20/2011 Physician New Zealand
Primary
Concomitant
Dyspnoea Hospitalization Male 5/24/2011 United States
Primary
Concomitant
Anaemia Hospitalization 8/22/2010 79 Male 6/1/2011 Physician United Kingdom
Primary
Concomitant
Dysphagia Hospitalization 8/22/2010 79 Male 6/13/2011 Physician United Kingdom
Primary
Concomitant
Bone Pain Male 196 lb 6/13/2011 Physician Netherlands
Primary
Concomitant
Dizziness Male 6/27/2011 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 6/20/2011 78 Male 337 lb 7/1/2011 Physician United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious Female 7/11/2011 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious 6/7/2011 71 Male 260 lb 7/15/2011 Physician Germany
Primary
Concomitant
Constipation 7/1/2011 70 Male 205 lb 7/19/2011 United States
Primary
Concomitant
Rash 6/12/2011 7/21/2011 United States
Primary
Concomitant
Liver Function Test Abnormal 7/6/2011 71 Male 7/25/2011 United States
Primary
Concomitant
Myocardial Ischaemia Other Serious 1/25/2011 54 Female 181 lb 7/27/2011 Physician Brazil
Primary
Concomitant
Fatigue Other Serious Female 7/29/2011 Physician United States
Primary
Concomitant
Diarrhoea 2/18/2011 52 Female 143 lb 7/29/2011 Physician United States
Primary
Concomitant
Arterial Disorder Hospitalization Female 139 lb 8/2/2011 Physician France
Primary
Concomitant
Acute Myocardial Infarction Other Serious 9/29/2010 60 Male 280 lb 8/2/2011 Physician Brazil
Primary
Concomitant
Liver Function Test Abnormal 7/6/2011 71 Male 8/3/2011 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected Male 8/4/2011 United States
Primary
Secondary
Concomitant
Concomitant Disease Aggravated Other Serious Male 8/9/2011 Other Health Professional Italy
Primary
Concomitant
Platelet Count Decreased Other Serious Female 8/22/2011 Physician United States
Primary
Concomitant
Drug Interaction Other Serious 7/25/2011 69 Female 165 lb 9/6/2011 Physician Denmark
Primary
Interacting
Therapeutic Response Unexpected Male 9/6/2011 United States
Primary
Secondary
Concomitant
Acute Myocardial Infarction Other Serious 9/29/2010 60 Male 280 lb 9/7/2011 Physician Brazil
Primary
Concomitant
Atrial Fibrillation Hospitalization 7/25/2011 69 Female 165 lb 9/6/2011 Physician
Primary
Secondary
Concomitant
Myalgia Other Serious 1/25/2011 68 Male 229 lb 9/20/2011 Physician Germany
Primary
Concomitant
Acute Myocardial Infarction Death 9/29/2010 60 Male 280 lb 9/29/2011 Physician Brazil
Primary
Concomitant
Hypertrophy Other Serious 6/7/2011 71 Male 260 lb 9/30/2011 Physician Germany
Primary
Concomitant
Alopecia Female 10/10/2011 United States
Primary
Concomitant
Diarrhoea 9/30/2010 59 Male 10/11/2011 Physician United States
Primary
Concomitant
Intention Tremor 9/1/2011 75 Male 10/19/2011 Physician Spain
Primary
Concomitant
Drug Hypersensitivity Female 148 lb 10/21/2011 Physician United States
Primary
Concomitant
Lipids Increased Other Serious Male 11/2/2011 Consumer United States
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 10/14/2011 66 Female 142 lb 11/2/2011 Physician United Kingdom
Primary
Concomitant
Condition Aggravated Hospitalization 6/16/2011 69 Female 139 lb 11/4/2011 Physician France
Primary
Concomitant
Arterial Disorder Other Serious 6/16/2011 69 Female 139 lb 11/8/2011 Physician France
Primary
Concomitant
Blood Sodium Abnormal Other Serious 6/21/2011 69 Female 165 lb 11/11/2011 Other Health Professional Denmark
Primary
Interacting
Blood Creatine Phosphokinase Increased Hospitalization 10/14/2011 66 Female 142 lb 11/11/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Arterial Disorder Disability 11/24/2010 69 Female 139 lb 11/15/2011 Physician France
Primary
Concomitant
Blood Sodium Decreased Hospitalization 6/21/2011 69 Female 165 lb 11/10/2011 Physician
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 6/21/2011 69 Female 165 lb 11/22/2011 Physician
Primary
Secondary
Concomitant
Dyspnoea Other Serious Male 12/5/2011 United States
Primary
Secondary
Concomitant
Abdominal Pain Hospitalization 8/1/2011 68 Female 12/7/2011 Other Health Professional United States
Primary
Concomitant
Lipids Increased Other Serious Male 12/8/2011 Consumer United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 11/23/2011 84 Male 12/13/2011 Physician United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 4/6/2011 70 Male 150 lb 12/14/2011 Physician Germany
Primary
Concomitant
Intermittent Claudication Other Serious 1/1/2010 59 Female 106 lb 12/15/2011 Other Health Professional Netherlands
Primary
Concomitant
Rash 7/1/2011 70 Male 205 lb 12/16/2011 United States
Primary
Concomitant
Blood Bilirubin Increased Hospitalization 11/23/2011 84 Male 12/20/2011 United States
Primary
Concomitant
Arteriosclerosis Other Serious 12/15/2010 62 Female 12/29/2011 Physician Germany
Primary
Concomitant
Peripheral Ischaemia Other Serious 9/1/2011 64 Male 229 lb 12/31/2011 Physician New Zealand
Primary
Concomitant
Pancytopenia 11/18/2009 68 Male 158 lb 1/2/2012 Physician United Kingdom
Primary
Concomitant
Liver Function Test Abnormal 2/1/2011 66 Male 179 lb 1/3/2012 Consumer Germany
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 12/20/2011 Male 1/9/2012 Physician Tunisia
Primary
Concomitant
Blood Creatinine Increased Disability 11/10/2011 73 Male 172 lb 1/10/2012 Physician Netherlands
Primary
Concomitant
Pruritus 12/1/2011 63 Female 1/20/2012 United States
Primary
Concomitant
Drug Ineffective Other Serious 11/18/2009 68 Male 158 lb 1/18/2012 Physician United Kingdom
Primary
Concomitant
Chest Pain Other Serious 11/16/2010 86 Male 161 lb 1/23/2012 Physician Germany
Primary
Concomitant
Septic Shock Hospitalization 12/17/2011 66 Male 1/30/2012 Consumer United States
Primary
Concomitant
Muscle Spasms 1/1/2012 64 Female 150 lb 2/6/2012 Consumer United States
Primary
Concomitant
Peripheral Ischaemia Other Serious 9/1/2011 64 Male 229 lb 2/7/2012 Physician New Zealand
Primary
Concomitant
Blood Glucose Increased Other Serious Male 2/8/2012 Consumer United States
Primary
Concomitant
Nausea 58 Female 2/16/2012 Consumer United States
Primary
Concomitant
Dry Skin Hospitalization 10/1/2009 72 Female 143 lb 2/21/2012 Physician Germany
Primary
Concomitant
Abdominal Pain Female 2/21/2012 Other Health Professional United States
Primary
Concomitant
Angina Pectoris Other Serious Female 2/23/2012 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 5/14/2011 46 Female 2/24/2012 Physician United States
Primary
Concomitant
Left Ventricular Hypertrophy Hospitalization 2/8/2011 80 Female 240 lb 2/29/2012 Physician United States
Primary
Concomitant
Pain Hospitalization 10/1/2009 72 Female 146 lb 3/1/2012 Other Health Professional Germany
Primary
Concomitant
Dyspnoea Other Serious Male 3/2/2012 Consumer United States
Primary
Concomitant
Dyspnoea Exertional Hospitalization 2/13/2012 70 Male 225 lb 3/6/2012 Physician Germany
Primary
Concomitant
Fluid Retention Other Serious 7/1/2011 Female 3/9/2012 Other Health Professional Denmark
Primary
Interacting
Tongue Disorder 2/21/2012 82 Male 3/9/2012 Physician Spain
Primary
Concomitant
Rhabdomyolysis Other Serious 57 Male 3/21/2012 Physician Germany
Primary
Concomitant
Blood Cholesterol Increased Female 126 lb 4/2/2012 Other Health Professional United Kingdom
Primary
Concomitant
Atrial Fibrillation Other Serious 2/14/2012 82 Male 167 lb 4/3/2012 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious Female 260 lb 4/4/2012 Consumer United States
Primary
Concomitant
Bundle Branch Block Left Other Serious Female 4/5/2012 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization Female 4/13/2012 Physician United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious Female 2/7/2012 Consumer United States
Primary
Concomitant
Pruritus 3/28/2012 79 Female 4/20/2012 Consumer United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious Female 2/7/2012 Physician United States
Primary
Concomitant
Abdominal Pain Hospitalization 8/1/2011 68 Female 2/7/2012 Other Health Professional United States
Primary
Concomitant
Pancreatitis Other Serious 65 Male 2/7/2012 Consumer United States
Primary
Secondary
Concomitant
Hangover Other Serious 4/11/2011 67 Male 220 lb 2/7/2012 Physician United States
Primary
Concomitant
Death Death 4/17/2012 81 Male 4/27/2012 Consumer United States
Primary
Concomitant
Vomiting Other Serious 4/11/2012 66 Female 146 lb 4/27/2012 Physician Germany
Primary
Concomitant
Cardiac Disorder Death Male 5/4/2012 Consumer United States
Primary
Concomitant
Tachyarrhythmia Hospitalization 2/23/2012 5/7/2012 Physician Germany
Primary
Concomitant
Rash 66 Male 5/8/2012 Physician Sweden
Primary
Concomitant
Necrosis Ischaemic Other Serious 1/1/2008 68 Male 187 lb 5/16/2012 Consumer France
Primary
Secondary
Concomitant
Concomitant Disease Progression Hospitalization 2/8/2011 80 Female 240 lb 5/10/2012 Other Health Professional United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 2/8/2011 80 Female 240 lb 5/17/2012 Other Health Professional United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 2/3/2011 70 Male 196 lb 5/21/2012 Physician Germany
Primary
Concomitant
Tachyarrhythmia Hospitalization 2/23/2012 5/25/2012 Physician Germany
Primary
Concomitant
Fluid Retention Female 5/25/2012 Physician United States
Primary
Concomitant
Cardiac Disorder Death Male 5/25/2012 Consumer United States
Primary
Concomitant
Cardiac Disorder Death Male 5/29/2012 Consumer United States
Primary
Concomitant
Anaphylactic Reaction Hospitalization 4/6/2011 70 Male 132 lb 5/31/2012 Physician Germany
Primary
Concomitant
Vomiting Hospitalization 4/11/2012 66 Female 146 lb 6/4/2012 Physician Germany
Primary
Concomitant
Dyspnoea Hospitalization 11/16/2010 86 Male 165 lb 6/5/2012 Physician Germany
Primary
Concomitant
Rash 4/19/2012 71 Female 6/6/2012 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data