Doxycycline combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Overdose Death 69 Female 4/24/2006 United Kingdom
Primary
Secondary
Treatment Noncompliance Hospitalization 2/26/2006 Male 258 lb 5/2/2006 Pharmacist United States
Primary
Secondary
Concomitant
Intentional Overdose Death 69 Female 5/5/2006 United Kingdom
Primary
Secondary
Concomitant
Therapeutic Response Decreased Hospitalization 1/27/2006 53 Male 218 lb 2/23/2006 Pharmacist United States
Primary
Concomitant
Infection Hospitalization 6/5/2006 86 Male 160 lb 8/21/2006 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 9/7/2006 46 Male 1/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urine Output Decreased Hospitalization 2/26/2007 85 Male 204 lb 3/29/2007 Pharmacist United States
Primary
Secondary
Concomitant
Nipple Pain 12/1/2006 66 Male 154 lb 4/12/2007 Consumer United States
Primary
Concomitant
Rhabdomyolysis Life Threatening Male 7/11/2007 Pharmacist United States
Primary
Secondary
Concomitant
Hepatitis Life Threatening 4/27/2007 77 Male 7/20/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Mouth Ulceration Disability 5/8/2007 89 Female 9/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Male 9/19/2007 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Life Threatening 7/5/2007 72 Male 273 lb 10/31/2007 Consumer United Kingdom
Primary
Concomitant
Pharmaceutical Product Complaint 5/17/2007 61 Female 2/5/2008 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 2/5/2008 Female 176 lb 4/18/2008 Physician Netherlands
Primary
Secondary
Concomitant
Osteomyelitis Life Threatening 1/1/2008 63 Male 10/15/2008 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 8/22/2008 Female 210 lb 12/12/2008 United States
Primary
Concomitant
Constipation 1/1/2009 Male 1/23/2009 Consumer
Primary
Concomitant
Oedema Peripheral 2/10/2009 Female 193 lb 2/10/2009 Physician United States
Primary
Concomitant
Overdose Hospitalization 12/1/2008 Female 216 lb 2/27/2009 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 1/26/2009 90 Male 3/5/2009 Other Health Professional United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Other Serious 1/26/2009 90 Male 3/11/2009 Other Health Professional United Kingdom
Primary
Concomitant
Psychotic Disorder Hospitalization 6/11/2004 53 Male 204 lb 4/1/2009 United States
Primary
Secondary
Concomitant
Hyperhidrosis Hospitalization 3/1/2009 Female 210 lb 5/26/2009 Consumer United Kingdom
Primary
Concomitant
Tooth Extraction Other Serious 9/5/2006 Female 6/9/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 261 lb 7/17/2009 Consumer United States
Primary
Concomitant
Tongue Oedema Hospitalization 4/29/2009 62 Female 7/14/2009 Other Health Professional Sweden
Primary
Concomitant
Weight Increased Life Threatening 57 Female 8/3/2009 United States
Primary
Concomitant
Weight Increased Life Threatening 57 Female 8/11/2009 United States
Primary
Concomitant
Wound Infection Other Serious 1/1/2009 60 Female 8/21/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 62 Female 8/25/2009 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 67 Female 9/2/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 61 Female 9/2/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 61 Female 9/2/2009 Lawyer United States
Primary
Concomitant
Respiratory Distress Hospitalization 71 Male 9/8/2009 United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 2/12/2009 59 Female 9/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Other Serious 2/12/2009 59 Female 9/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Perforated Duodenal Ulcer Repair Hospitalization 8/25/2009 61 Male 9/17/2009 Physician United Kingdom
Primary
Concomitant
Duodenal Ulcer Perforation Hospitalization 8/25/2009 61 Male 9/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus 1/1/2004 49 Male 144 lb 9/23/2009 United States
Primary
Concomitant
Vomiting Hospitalization 56 Female 9/17/2009 United States
Primary
Concomitant
Vomiting Hospitalization 53 Female 9/24/2009 United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 6/24/2007 Male 209 lb 10/6/2009 Consumer United States
Primary
Concomitant
Ill-defined Disorder Disability Male 319 lb 10/15/2009 Other Health Professional United States
Primary
Concomitant
Tooth Extraction Other Serious 9/5/2006 Female 10/19/2009 Other Health Professional United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 6/24/2007 Male 209 lb 10/27/2009 Consumer United States
Primary
Concomitant
Spinal Osteoarthritis Hospitalization 71 Male 10/22/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 53 Female 11/4/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 71 Male 11/4/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 61 Female 11/4/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 61 Female 11/17/2009 Lawyer United States
Primary
Concomitant
Wound Hospitalization 71 Male 11/19/2009 United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 50 Male 11/18/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 261 lb 12/1/2009 Consumer United States
Primary
Concomitant
Thrombocytopenia Life Threatening 9/18/2009 Female 154 lb 12/8/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 9/7/2009 55 Female 12/1/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 53 Female 12/10/2009 United States
Primary
Concomitant
Vomiting Life Threatening 11/19/2009 Female 12/29/2009 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 10/1/2007 74 Female 172 lb 12/30/2009 Physician United States
Primary
Concomitant
Infarction Life Threatening 1/9/2010 Male 95 lb 1/15/2010 Consumer United States
Primary
Secondary
Concomitant
Wound Hospitalization 71 Male 1/11/2010 United States
Primary
Concomitant
Skin Exfoliation 8/30/2009 67 Male 1/29/2010 Consumer United States
Primary
Secondary
Concomitant
Pain Other Serious 51 Male 1/22/2010 United States
Primary
Concomitant
Wound Hospitalization 71 Male 1/22/2010 Lawyer United States
Primary
Concomitant
Renal Impairment Other Serious 12/22/2009 73 Female 2/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Life Threatening 11/19/2009 Female 2/4/2010 Physician United States
Primary
Concomitant
Pulmonary Fibrosis Hospitalization 12/3/2009 73 Male 163 lb 2/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 12/22/2009 73 Female 2/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Life Threatening 11/19/2009 Female 2/10/2010 Physician United States
Primary
Concomitant
Renal Impairment Life Threatening 12/22/2009 73 Female 2/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Parkinson's Disease Other Serious 2/1/2010 80 Female 182 lb 2/8/2010 Physician United States
Primary
Concomitant
Renal Impairment Other Serious 12/22/2009 73 Female 2/15/2010 Other Health Professional
Primary
Secondary
Vomiting Life Threatening 11/19/2009 Female 2/15/2010 Physician United States
Primary
Concomitant
Renal Impairment Other Serious 73 Female 2/8/2010 United Kingdom
Primary
Secondary
Toxic Epidermal Necrolysis Other Serious 6/24/2007 Male 209 lb 3/1/2010 Consumer United States
Primary
Concomitant
Suicide Attempt Other Serious 12/18/2007 61 Male 141 lb 3/1/2010 United Kingdom
Primary
Concomitant
Infarction Life Threatening 1/9/2010 Male 95 lb 3/8/2010 Consumer United States
Primary
Secondary
Concomitant
Skin Laceration Other Serious 1/2/2010 81 Male 207 lb 3/3/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 9/5/2006 Female 3/15/2010 Other Health Professional United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 9/5/2006 Female 3/23/2010 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 9/5/2006 Female 3/31/2010 Physician United States
Primary
Concomitant
Haemoglobin Decreased Other Serious 1/2/2010 81 Male 207 lb 4/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vascular Anomaly Other Serious 1/1/2003 4/6/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 58 Female 4/8/2010 Physician United States
Primary
Concomitant
Product Adhesion Issue Other Serious 1/1/1996 40 Female 147 lb 4/14/2010 Physician United States
Primary
Concomitant
Vascular Anomaly Other Serious 1/1/2003 4/15/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 4/2/2001 4/15/2010 United States
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 11/1/2007 53 Male 170 lb 4/15/2010 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 53 Female 4/15/2010 United States
Primary
Concomitant
Vascular Anomaly Other Serious 1/1/2003 4/26/2010 United States
Primary
Concomitant
Spirometry Abnormal Other Serious 11/6/2008 40 Male 4/26/2010 Other Health Professional Switzerland
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 58 Female 4/27/2010 Physician United States
Primary
Concomitant
Vascular Anomaly Other Serious 1/1/2003 4/28/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 58 Female 5/3/2010 Physician United States
Primary
Concomitant
Vascular Anomaly Other Serious 1/1/2003 5/4/2010 United States
Primary
Concomitant
Rash Other Serious 10/1/2008 54 Male 176 lb 5/5/2010 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Other Serious 4/2/2001 5/6/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2003 5/10/2010 United States
Primary
Concomitant
Neutropenia Hospitalization 4/1/2010 59 Male 231 lb 5/14/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2003 5/27/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2003 6/4/2010 United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/2/2001 6/9/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2003 6/10/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2003 6/16/2010 United States
Primary
Concomitant
Weight Increased Other Serious 4/2/2001 6/16/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2003 6/22/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 58 Female 6/24/2010 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 5/26/2010 79 Male 7/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Wound Drainage Other Serious 4/2/2001 7/13/2010 United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2008 54 Female 7/15/2010 Lawyer United States
Primary
Concomitant
Pruritus 11/1/2007 68 Female 139 lb 7/17/2010 Consumer United States
Primary
Secondary
Concomitant
Product Adhesion Issue Other Serious 1/1/1996 40 Female 147 lb 8/2/2010 Physician United States
Primary
Concomitant
X-ray Abnormal Other Serious 1/1/1998 52 Female 8/5/2010 United States
Primary
Secondary
Concomitant
Vertigo Other Serious 62 Female 182 lb 8/16/2010 Lawyer United States
Primary
Concomitant
X-ray Abnormal Other Serious 1/1/1998 52 Female 8/20/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2003 8/24/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/11/2006 69 Male 202 lb 8/25/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/11/2006 69 Male 202 lb 8/28/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 58 Female 8/30/2010 Physician United States
Primary
Concomitant
No Adverse Event 8/8/2010 64 Male 220 lb 9/8/2010 Consumer United States
Primary
Concomitant
Respiratory Failure Other Serious 1/1/2008 54 Female 84 lb 9/8/2010 Other Health Professional United States
Primary
Concomitant
Platelet Count Decreased Other Serious 5/7/2010 72 Male 214 lb 9/9/2010 United States
Primary
Concomitant
Vomiting Hospitalization 4/1/2010 50 Female 9/9/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 58 Female 9/9/2010 Physician United States
Primary
Concomitant
Vomiting Hospitalization 4/1/2010 50 Female 9/13/2010 Consumer United States
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 6/17/2010 66 Male 284 lb 9/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious Female 185 lb 9/20/2010 Consumer United States
Primary
Concomitant
Suicidal Ideation Other Serious 9/1/2007 42 Male 9/22/2010 Lawyer United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 9/5/2006 63 Female 9/22/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 58 Female 9/24/2010 Physician United States
Primary
Concomitant
Pneumonia Fungal Other Serious 5/7/2010 72 Male 214 lb 9/27/2010 United States
Primary
Concomitant
X-ray Abnormal Other Serious 1/1/1998 52 Female 9/29/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 58 Female 10/15/2010 Physician United States
Primary
Concomitant
Thrombosis Other Serious 10/1/2007 74 Female 172 lb 10/15/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 58 Female 10/20/2010 Physician United States
Primary
Concomitant
Blood Glucose Decreased 2/25/2010 55 Female 249 lb 10/25/2010 Consumer United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/1/1998 52 Female 11/9/2010 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 10/24/2010 52 Male 157 lb 11/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/3/2007 78 Female 150 lb 11/18/2010 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Other Serious 1/1/2008 54 Female 84 lb 11/19/2010 Other Health Professional United States
Primary
Concomitant
X-ray Abnormal Other Serious 1/25/1998 52 Female 11/29/2010 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 10/24/2010 52 Male 157 lb 11/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Dysphonia 9/1/2010 81 Female 12/9/2010 Consumer
Primary
Concomitant
Vomiting Other Serious 11/14/2010 80 Female 119 lb 12/9/2010 Other Health Professional United Kingdom
Primary
Concomitant
Rash 12/13/2010 Consumer United States
Primary
Concomitant
Rash Generalised Other Serious 12/1/2009 12/19/2010 Consumer United States
Primary
Concomitant
X-ray Abnormal Other Serious 1/25/1998 52 Female 12/21/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 50 Male 12/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Subdural Haemorrhage Death 11/21/2010 76 Male 12/14/2010 Other Health Professional United States
Primary
Concomitant
X-ray Abnormal Other Serious 1/25/1998 52 Female 12/30/2010 United States
Primary
Secondary
Concomitant

Drug Data